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  1. Evidence based medicine depends on unbiased selection of completed randomized controlled trials. For completeness it is important to publish all trials. This report describes the first large randomised control...

    Authors: Bart J Veldt, Johannes T Brouwer, Michael Adler, Frederik Nevens, Peter Michielsen, Jean Delwaide, Bettina E Hansen and Solko W Schalm
    Citation: BMC Gastroenterology 2003 3:24
    Content type: Research article Published on:

  2. Anal sphincter defects have been shown to increase pressure asymmetry within the anal canal in patients with fecal incontinence. However, this correlation is far from perfect, and other factors may play a role...

    Authors: Henri Damon, Luc Henry, Sabine Roman, Xavier Barth and François Mion
    Citation: BMC Gastroenterology 2003 3:23
    Content type: Research article Published on:

  3. Since esophageal variceal bleeding is associated with a high mortality rate, prevention of bleeding might be expected to result in improved survival. The first trials to evaluate prophylactic sclerotherapy fou...

    Authors: Henk R van Buuren, Marijke C Rasch, Piet L Batenburg, Clemens JM Bolwerk, Jan J Nicolai, Sjoerd DJ van der Werf, Joost Scherpenisse, Lidia R Arends, Jan van Hattum, Erik AJ Rauws and Solko W Schalm
    Citation: BMC Gastroenterology 2003 3:22
    Content type: Research article Published on:

  5. In this study, we evaluated the prevalence of primary resistance of Brazilian H. pylori isolates to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone. In addition, the vacA, iceA, cagA an...

    Authors: Anita Paula Ortiz Godoy, Marcelo Lima Ribeiro, Yune Helena Borges Benvengo, Lea Vitiello, Maira de Carvalho Bueno Miranda, Sergio Mendonça and José Pedrazzoli Jr
    Citation: BMC Gastroenterology 2003 3:20
    Content type: Research article Published on:

  6. Hepatocellular carcinoma (HCC) is one of the most common malignancies in South East Asia. Although activation of the MEK-MAPK is often associated with cellular growth, the role of MEK-MAPK in growth and surviv...

    Authors: Hung Huynh, Thi Thanh Tuyen Nguyen, Kah-Hoe Kah-Pierce Chow, Puay Hoon Tan, Khee Chee Soo and Evelyne Tran
    Citation: BMC Gastroenterology 2003 3:19
    Content type: Research article Published on:

  7. Although endometriosis with sigmoid serosal involvement is not uncommon in women of childbearing age, the mucosal involvement is rare and differential diagnosis from colon cancer may be difficult due to the la...

    Authors: Philippos Dimoulios, Ioannis E Koutroubakis, Maria Tzardi, Pavlos Antoniou, Ioannis M Matalliotakis and Elias A Kouroumalis
    Citation: BMC Gastroenterology 2003 3:18
    Content type: Case report Published on:

  8. We previously identified eight known and novel genes differentially expressed in the small intestines of wild type and W/W V mice, which have greatly reduced populations of ...

    Authors: Yataro Daigo, Ichiro Takayama, Bruce AJ Ponder, Carlos Caldas, Sean M Ward, Kenton M Sanders and Masayuki A Fujino
    Citation: BMC Gastroenterology 2003 3:17
    Content type: Research article Published on:

  10. Endoscopic colorectal cancer (CRC) screening is currently implemented in many countries. Since endoscopes cannot be sterilised, the transmission of infectious agents through endoscopes has been a matter of con...

    Authors: Michael Bretthauer, Anita Jørgensen, Bjørn Erik Kristiansen, Bjørn Hofstad and Geir Hoff
    Citation: BMC Gastroenterology 2003 3:15
    Content type: Research article Published on:

  11. The muscle layers of murine gastric fundus have no interstitial cells of Cajal at the level of the myenteric plexus and only possess intramuscular interstitial cells and this tissue does not generate electric ...

    Authors: Yataro Daigo, Ichiro Takayama, Bruce AJ Ponder, Carlos Caldas, Sean M Ward, Kenton M Sanders and Masayuki A Fujino
    Citation: BMC Gastroenterology 2003 3:14
    Content type: Research article Published on:

  12. Phytobezoar may be a cause of bowel obstruction in patients with previous gastric surgery. Most bezoars are concretions of poorly digested food, which are usually formed initially in the stomach. Intestinal ob...

    Authors: Michail Pitiakoudis, Alexandra Tsaroucha, Konstantinos Mimidis, Theodoros Constantinidis, Stavros Anagnostoulis, George Stathopoulos and Constantinos Simopoulos
    Citation: BMC Gastroenterology 2003 3:13
    Content type: Case report Published on:

  13. Most of the previous studies regarding the effects of gel-forming fibres have considered the gastric emptying of liquid or solid meals after the addition of pectin or guar gum. The influence of locust bean gum...

    Authors: Gassan Darwiche, Ola Björgell and Lars-olof Almér
    Citation: BMC Gastroenterology 2003 3:12
    Content type: Research article Published on:

  14. Since its introduction in the early 1980s, percutaneous endoscopic gastrostomy has become the most popular method for performing a gastrostomy for long-term enteral feeding. It has been associated, however, wi...

    Authors: Kalliopi Papakonstantinou, Athanasios Karagiannis, Maria Tsirantonaki, Anastasios Konstantinidis, Spiros Spirou, Ion Skottis and Andreas Karabinis
    Citation: BMC Gastroenterology 2003 3:11
    Content type: Case report Published on:

  16. Various causes of malabsorption syndrome (MAS) are associated with intestinal stasis that may cause small intestinal bacterial overgrowth (SIBO). Frequency, nature and antibiotic sensitivity of SIBO in patient...

    Authors: Ujjala Ghoshal, Uday C Ghoshal, Piyush Ranjan, Subhash R Naik and Archana Ayyagari
    Citation: BMC Gastroenterology 2003 3:9
    Content type: Research article Published on:

  17. Celiac disease may manifest with a variety of symptoms which can result in delays in diagnosis. Celiac disease is associated with a number of other medical conditions. The last national survey of members of th...

    Authors: Ann Cranney, Marion Zarkadas, Ian D Graham and Connie Switzer
    Citation: BMC Gastroenterology 2003 3:8
    Content type: Research article Published on:

  18. The aim of this study was to assess the prognostic accuracy of Child-Pugh and APACHE II and III scoring systems in predicting short-term, hospital mortality of patients with liver cirrhosis.

    Authors: Constantinos Chatzicostas, Maria Roussomoustakaki, Georgios Notas, Ioannis G Vlachonikolis, Demetrios Samonakis, John Romanos, Emmanouel Vardas and Elias A Kouroumalis
    Citation: BMC Gastroenterology 2003 3:7
    Content type: Research article Published on:

  19. Gastric tuberculosis is rare, and usually associated with pulmonary tuberculosis or an immunodeficient state. Here, we report five cases of gastric tuberculosis in immunocompetent patients without evidence of ...

    Authors: Deepak N Amarapurkar, Nikhil D Patel and Anjali D Amarapurkar
    Citation: BMC Gastroenterology 2003 3:6
    Content type: Case report Published on:

  20. Proper histomorphological interpretation of intestinal acute graft versus host disease (A-GVHD) associated with allogeneic bone marrow transplantation (BMT) is critical for clinical managaement. However, studi...

    Authors: Vinod B Shidham, Chung-Che Chang, Ganesh Shidham, Farrukh Ghazala, Paul F Lindholm, Bal Kampalath, Varghese George and Richard Komorowski
    Citation: BMC Gastroenterology 2003 3:5
    Content type: Research article Published on:

  21. The peculiar anatomy of pancreatic ducts in pancreas divisum (PD) may interfere with the development of acute chronic pancreatitis. In the presented case, PD influenced the evolution of lesions after pancreati...

    Authors: Evangelia G Chryssou, Panos Prassopoulos, John Mouzas, Thomas G Maris and Nicholas Gourtsoyiannis
    Citation: BMC Gastroenterology 2003 3:4
    Content type: Case report Published on:

  22. Enhanced expression of MAdCAM-1 (mucosal addressin cell adhesion molecule-1) is associated with the onset and progression of inflammatory bowel disease. The clinical significance of elevated MAdCAM-1 expressio...

    Authors: Makoto Sasaki, Paul Jordan, Jeff Houghton, Xianmin Meng, Makoto Itoh, Takashi Joh and J Steven Alexander
    Citation: BMC Gastroenterology 2003 3:3
    Content type: Research article Published on:

  23. Dieulafoy's lesion is an uncommon but important cause of recurrent upper gastrointestinal bleeding. Extragastric location of Dieulafoy's lesion is rare. We report two cases of Dieulafoy's lesion of the duodenu...

    Authors: Mohammed Ibrarullah and Gajanan D Wagholikar
    Citation: BMC Gastroenterology 2003 3:2
    Content type: Case report Published on:

  25. In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model system for gallbladder epithelium, were examined for their...

    Authors: Christopher E Savard, Thane A Blinman, Ho-Soon Choi, Sung-Koo Lee, Stephen J Pandol and Sum P Lee
    Citation: BMC Gastroenterology 2002 2:23
    Content type: Research article Published on:

  26. Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide synthase plays a part in this mechanism has however not yet...

    Authors: Ferdinand Serracino-Inglott, Ioannis T Virlos, Nagy A Habib, Robin CN Williamson and Robert T Mathie
    Citation: BMC Gastroenterology 2002 2:22
    Content type: Research article Published on:

  28. The cytotoxin associated gene A (cagA), and the vacuolating cytotoxin gene A (vacA) of Helicobacter pylori have been associated to phenotypic characteristics of virulence. The objectives of this study were to det...

    Authors: Gustavo Faundez, Miriam Troncoso and Guillermo Figueroa
    Citation: BMC Gastroenterology 2002 2:20
    Content type: Research article Published on:

  29. It has been suggested that intrasphincteric injection of botulinum toxin (BTX) may represent an alternative therapy to balloon dilatation in achalasia. The aim of the present study was to test the effectivenes...

    Authors: M Storr, P Born, E Frimberger, N Weigert, T Rösch, A Meining, M Classen and HD Allescher
    Citation: BMC Gastroenterology 2002 2:19
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Gastroenterology 2003 3:32

  31. Gastric ulcers are a frequent problem in the United States. Proton pump inhibitors have been shown to increase healing rates and improve clinical symptoms. The objective of this study is to compare gastric ulc...

    Authors: Maribel Salas, Alexandra Ward and Jaime Caro
    Citation: BMC Gastroenterology 2002 2:17
    Content type: Research article Published on:

  32. Cathepsin B is thought to play a central role in intrapancreatic trypsinogen activation and the onset of pancreatitis. A recent investigation of the cathepsin B mediated activability of wildtype trypsinogen an...

    Authors: Niels Teich, Hans Bödeker and Volker Keim
    Citation: BMC Gastroenterology 2002 2:16
    Content type: Research article Published on:

  33. Bouveret's syndrome is an unusual presentation of duodenal obstruction caused by the passage of a large gallstone through a cholecystoduodenal fistula. Endoscopic therapy has been used as first-line treatment,...

    Authors: Mohammad M Alsolaiman, Christoph Reitz, Ali T Nawras, John B Rodgers and Benedict J Maliakkal
    Citation: BMC Gastroenterology 2002 2:15
    Content type: Case report Published on:

  35. Biochemical and histochemical studies have both previously indicated plasma membrane-associated carbonic anhydrase (CA) activity in hepatocytes which has been assumed to be CA IV. However, immunohistochemical ...

    Authors: Seppo Parkkila, Antti J Kivelä, Kari Kaunisto, Anna-Kaisa Parkkila, Jukka Hakkola, Hannu Rajaniemi, Abdul Waheed and William S Sly
    Citation: BMC Gastroenterology 2002 2:13
    Content type: Research article Published on:

  37. To evaluate changes in H pylori infection prevalence in Greece during a ten-year period, and to examine its antigenic profile.

    Authors: Periklis Apostolopoulos, Irene Vafiadis-Zouboulis, Michael Tzivras, Dimitrios Kourtessas, Nicolaos Katsilambros and Athanasios Archimandritis
    Citation: BMC Gastroenterology 2002 2:11
    Content type: Research article Published on:

  38. Intestinal tuberculosis is a rare disease in western countries, affecting mainly immigrants and immunocompromised patients. Intestinal tuberculosis is a diagnostic challenge, especially when active pulmonary i...

    Authors: Constantinos Chatzicostas, Ioannis E Koutroubakis, Maria Tzardi, Maria Roussomoustakaki, Panagiotis Prassopoulos and Elias A Kouroumalis
    Citation: BMC Gastroenterology 2002 2:10
    Content type: Case report Published on:

  39. Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of inflammatory bowel disease (IBD). Melatonin, a relatively safe, p...

    Authors: Makoto Sasaki, Paul Jordan, Takashi Joh, Makotoh Itoh, Michael Jenkins, Kevin Pavlick, Alireza Minagar and Steven J Alexander
    Citation: BMC Gastroenterology 2002 2:9
    Content type: Research article Published on:

  40. It has been suggested that one aspect of non-steroidal anti-inflammatory drugs induced intestinal damage is due to either uncoupling of mitochondrial oxidative phosphorylation or inhibition of electron transpo...

    Authors: S Somasundaram, R Simpson, S Rafi, JK Shergill, I Bjarnason and J Wrigglesworth
    Citation: BMC Gastroenterology 2002 2:8
    Content type: Research article Published on:

  42. Helicobacter pylori (H. pylori) has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patient with H. py...

    Authors: Uday C Ghoshal, Debashish Guha, Santu Bandyopadhyay, Chiranjib Pal, Srikanta Chakraborty, Ujjala Ghoshal, Tamal K Ghosh, Bhaskar B Pal and Prabir K Banerjee
    Citation: BMC Gastroenterology 2002 2:6
    Content type: Case report Published on:

  43. An increased prevalence of coeliac disease in patients with primary biliary cirrhosis has been recently reported. However, in other studies the association has not been confirmed. There have been no formal att...

    Authors: Costantinos Chatzicostas, Maria Roussomoustakaki, Dimitrios Drygiannakis, Maria Niniraki, Maria Tzardi, Mary Koulentaki, Philippos Dimoulios, Ioannis Mouzas and Elias Kouroumalis
    Citation: BMC Gastroenterology 2002 2:5
    Content type: Research article Published on:

  44. Absorption of water and Na+ in descending colonic crypts is dependent on the barrier function of the surrounding myofibroblastic pericryptal sheath. Here the effects of high and low Na+ diets and exposure to whol...

    Authors: Jay R Thiagarajah, Nina M Griffiths, Kevin C Pedley and Richard J Naftalin
    Citation: BMC Gastroenterology 2002 2:4
    Content type: Research article Published on:

  45. Cholelithiasis is the gallstone disease (GSD) where stones are formed in the gallbladder. The main function of the gallbladder is to concentrate bile by the absorption of water and sodium. GSD has high prevale...

    Authors: Oleg Kleiner, Jagannathan Ramesh, Mahmoud Huleihel, Beny Cohen, Keren Kantarovich, Chen Levi, Boris Polyak, Robert S Marks, Jacov Mordehai, Zahavi Cohen and Shaul Mordechai
    Citation: BMC Gastroenterology 2002 2:3
    Content type: Research article Published on:

  46. Alcoholic hepatitis is characterized by acute, or acute-on-chronic hepatic failure and associated with a high mortality. Specific therapies should be considered for those at high risk of mortality. The Mayo En...

    Authors: Milan Sheth, Mark Riggs and Tushar Patel
    Citation: BMC Gastroenterology 2002 2:2
    Content type: Research article Published on:

  47. Health Related Quality of Life (HRQoL) is an important outcome measure in Inflammatory Bowel Disease (IBD). The aim of our study was to assess HRQoL in a population of 135 Greek patients with IBD.

    Authors: Athanasios G Pallis, Ioannis G Vlachonikolis and Ioannis A Mouzas
    Citation: BMC Gastroenterology 2002 2:1
    Content type: Research article Published on:

  48. High dose interferon induction treatment of hepatitis C viral infection blocks viral production over 95%. Since dose reduction is often performed due to clinical considerations, the effect of dose reduction on...

    Authors: Frank C Bekkering, Avidan U Neumann, Johannes T Brouwer, Rachel S Levi-Drummer and Solko W Schalm
    Citation: BMC Gastroenterology 2001 1:14
    Content type: Research article Published on:

  50. Since the introduction of molecular diagnostic tools such as markers for hepatitis C and different autoimmune diseases, liver biopsy is thought to be useful mainly for staging but not for diagnostic purposes. ...

    Authors: Claudia Spycher, Arthur Zimmermann and Juerg Reichen
    Citation: BMC Gastroenterology 2001 1:12
    Content type: Research article Published on:
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