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  1. Content type: Case report

    Mitochondrial neurogastrointestinal encephalopathy (MNGIE), due to mutations in TYMP, often presents with gastrointestinal symptoms. Two sisters, initially managed for Crohn’s disease based upon clinical, imaging...

    Authors: Ravi Patel, Lucia Lee Coulter, Joanna Rimmer, Miles Parkes, Patrick Francis Chinnery and Oscar Swift

    Citation: BMC Gastroenterology 2019 19:11

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  2. Content type: Research article

    Recent studies have found gut microbiota to be closely associated with onset and perpetuation of UC. Currently, studies about gut microbiota have mainly covered samples collected from the intestinal lumen. How...

    Authors: Ling-yan Pei, Yu-shi Ke, Huan-hu Zhao, Lin Wang, Chao Jia, Wei-zhi Liu, Qian-hui Fu, Meng-ni Shi, Jian Cui and Shu-chun Li

    Citation: BMC Gastroenterology 2019 19:10

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  3. Content type: Case report

    Hermansky-Pudlak syndrome (HPS) is a rare, genetically heterogeneous disorder that manifests oculocutaneous albinism together with bleeding diatheses that reflect a platelet storage pool deficiency. Ten geneti...

    Authors: Jun Ishihara, Tatsuki Mizuochi, Takashi Uchida, Yugo Takaki, Ken-ichiro Konishi, Masahiko Joo, Yasuhiko Takahashi, Shinichiro Yoshioka, Hironori Kusano, Yoji Sasahara and Yushiro Yamashita

    Citation: BMC Gastroenterology 2019 19:9

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  4. Content type: Research article

    Helicobacter pylori (H.pylori) infections are prevalent and recognized as major cause of gastrointestinal diseases in Ethiopia. However, Studies conducted on the prevalence, risk factors and other clinical forms ...

    Authors: Addisu Melese, Chalachew Genet, Balew Zeleke and Tesfaye Andualem

    Citation: BMC Gastroenterology 2019 19:8

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  5. Content type: Research article

    The incidence of Ulcerative colitis (UC) in Asia is increasing but reports on its long-term course are few. The aim of this study was to identify risk factors predictive of extent progression in Asian patients...

    Authors: Yun Qiu, Baili Chen, Yufei Li, Shanshan Xiong, Shenghong Zhang, Yao He, Zhirong Zeng, Shomron Ben-Horin, Minhu Chen and Ren Mao

    Citation: BMC Gastroenterology 2019 19:7

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  6. Content type: Research article

    The usage of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for the diagnosis of solid pancreatic cancer is increasing, however mainly retrospective studies are available about the detailed meth...

    Authors: Renáta Bor, Béla Vasas, Anna Fábián, Anita Bálint, Klaudia Farkas, Ágnes Milassin, László Czakó, Mariann Rutka, Tamás Molnár, Mónika Szűcs, László Tiszlavicz, László Kaizer, Sándor Hamar and Zoltán Szepes

    Citation: BMC Gastroenterology 2019 19:6

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  7. Content type: Database

    Inflammatory bowel disease (IBD) is a chronic complex disease of the gastrointestinal tract. Patients with IBD can experience a wide range of symptoms, but the pathophysiological mechanisms that cause these in...

    Authors: Floris Imhann, K. J. Van der Velde, R. Barbieri, R. Alberts, M. D. Voskuil, A. Vich Vila, V. Collij, L. M. Spekhorst, Van der Sloot KWJ, V. Peters, H. M. Van Dullemen, M. C. Visschedijk, Festen EAM, M. A. Swertz, G. Dijkstra and R. K. Weersma

    Citation: BMC Gastroenterology 2019 19:5

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  8. Content type: Research article

    We aimed to investigate how high-dose ecabet sodium affects low-dose aspirin-induced small intestinal mucosal injury in healthy volunteers.

    Authors: Kazuhiro Ota, Toshihisa Takeuchi, Yuichi Kojima, Satoshi Harada, Yuki Hirata, Noriaki Sugawara, Sadaharu Nouda, Kazuki Kakimoto, Takanori Kuramoto and Kazuhide Higuchi

    Citation: BMC Gastroenterology 2019 19:4

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  9. Content type: Research article

    Tissue inflammation in inflammatory bowel diseases (IBD) is associated with a decrease in local pH. The gene encoding G-protein-coupled receptor 65 (GPR65) has recently been reported to be a genetic risk facto...

    Authors: Irina V. Tcymbarevich, Jyrki J. Eloranta, Jean-Benoît Rossel, Nicole Obialo, Marianne Spalinger, Jesus Cosin-Roger, Silvia Lang, Gerd A. Kullak-Ublick, Carsten A. Wagner, Michael Scharl, Klaus Seuwen, Pedro A. Ruiz, Gerhard Rogler, Cheryl de Vallière and Benjamin Misselwitz

    Citation: BMC Gastroenterology 2019 19:2

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  10. Content type: Research article

    Many reports have documented the increasing impact of Clostridium difficile infection (CDI) in patients with ulcerative colitis (UC). We conducted a retrospective study to determine the incidence, clinical charac...

    Authors: Hui Xu, Hao Tang, Tao Xu, Meng Xiao, Ji Li, Bei Tan, Hong Yang, Hong Lv, Yue Li and Jiaming Qian

    Citation: BMC Gastroenterology 2019 19:3

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  11. Content type: Research article

    The long-term natural history of microscopic colitis (MC) (collagenous colitis (CC), lymphocytic colitis (LC)), traditionally considered relapsing but non-progressive diseases, is poorly defined. Whether persi...

    Authors: Alexander Levy, Nienke Z. Borren, Benjamin Maxner, William Tan, Danielle Bellavance, Kyle Staller, Daniel Chung, Hamed Khalili and Ashwin N. Ananthakrishnan

    Citation: BMC Gastroenterology 2019 19:1

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  12. Content type: Research article

    Intramucosal, histologically mixed-type, low-grade (LG), well-differentiated gastric tubular adenocarcinomas (tub1s; LG-tub1s) have larger mean diameters and exhibit a higher frequency of the gastric mucin phe...

    Authors: Takashi Saitoh, Asako Takamura and Gen Watanabe

    Citation: BMC Gastroenterology 2018 18:189

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  13. Content type: Research article

    Intestinal alkaline phosphatase (IAP) plays important role in gut homeostasis. We aimed to evaluate the expression of endogenous IAP and to assess the clinical course according to the expression of endogenous ...

    Authors: Seon-Young Park, Ji-Young Kim, Su-Mi Lee, Jin Ook Chung, Ji-Ho Seo, SunMin Kim, Dong Hyun Kim, Chang-Hwan Park, Jae-Kyun Ju, Young-Eun Joo, Jae-Hyuk Lee, Hyun-Soo Kim, Sung-Kyu Choi and Jong-Sun Rew

    Citation: BMC Gastroenterology 2018 18:188

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  14. Content type: Research article

    The role of progesterone receptor (PR) has been reported in a series of pancreatic cysts. However, the relationship between PR and prognosis of solid pseudopapillary neoplasm of the pancreas (SPNP) has not bee...

    Authors: Feiyang Wang, Zibo Meng, Shoukang Li, Yushun Zhang and Heshui Wu

    Citation: BMC Gastroenterology 2018 18:187

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  15. Content type: Research article

    To investigate the diagnostic performance of alpha-fetoprotein (AFP) and neutrophil-to-lymphocyte ratio (NLR) as well as their combinations with other markers.

    Authors: Jian Hu, Nianyue Wang, Yongfeng Yang, Li Ma, Ruilin Han, Wei Zhang, Cunling Yan, Yijie Zheng and Xiaoqin Wang

    Citation: BMC Gastroenterology 2018 18:186

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  16. Content type: Research article

    Exclusive enteral nutrition (EEN) is as effective as corticosteroids in inducing remission in children with Crohn’s disease (CD). However, over 50% of these children relapse by 12 months of diagnosis. Thiopuri...

    Authors: Christina Ong, Poh Ting Lim, Veena Logarajah, Maria Janelle Liwanag, Bi Xia Ang, Yuqin Cher, Fang Kuan Chiou and Ajmal Kader

    Citation: BMC Gastroenterology 2018 18:185

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  17. Content type: Research article

    Gastric Cancer is highly prevalent and deadly worldwide. In Colombia, it is the most lethal form of cancer. Some single-nucleotide polymorphisms in IL-10, IL-4, and IL-4Rα genes have been associated with an an...

    Authors: Denny Miley Cárdenas, Angie Carolina Sánchez, Daris Angélica Rosas, Esmeralda Rivero, Massiel Dayana Paparoni, Mildred Andreína Cruz, Yeicy Paola Suárez and Nestor Fabián Galvis

    Citation: BMC Gastroenterology 2018 18:184

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  18. Content type: Research article

    Blood loss from the gastrointestinal tract can be an acute and life-threatening event. For the treatment of gastrointestinal bleeding, it is important to accurately detect gastrointestinal bleeding and to loca...

    Authors: Yoichi Otomi, Hideki Otsuka, Kaori Terazawa, Moriaki Yamanaka, Yuki Obama, Maki Arase, Maki Otomo, Saho Irahara, Michiko Kubo, Naoto Uyama, Takashi Abe and Masafumi Harada

    Citation: BMC Gastroenterology 2018 18:183

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  19. Content type: Research article

    Pediatric patients always suffer from chronic pancreatitis (CP), especially those with steatorrhea. This study aimed to identify the incidence of and risk factors for steatorrhea in pediatric CP. To our best k...

    Authors: Lu Hao, Teng Wang, Lin He, Ya-Wei Bi, Di Zhang, Xiang-Peng Zeng, Lei Xin, Jun Pan, Dan Wang, Jun-Tao Ji, Ting-Ting Du, Jin-Huan Lin, Li-Sheng Wang, Wen-Bin Zou, Hui Chen, Ting Xie…

    Citation: BMC Gastroenterology 2018 18:182

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  20. Content type: Research article

    This study investigated the relationship between liver stiffness and carotid artery elasticity in patients with chronic viral hepatitis. We used an acoustic radiation force impulse (ARFI) technique to measure ...

    Authors: Jing-Hua Li, Ning Zhu, Ying-Bin Min, Xiang-Zhou Shi, Yun-You Duan and Yi-Lin Yang

    Citation: BMC Gastroenterology 2018 18:181

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  21. Content type: Research article

    Intrahepatic cholangiocarcinoma (ICC) is a relatively rare subtype of cholangiocarcinoma. The study herein gathered experience of surgical treatment for ICC, and aimed to analyze the prognosis of patients who ...

    Authors: Kun-Ming Chan, Chun-Yi Tsai, Chun-Nan Yeh, Ta-Sen Yeh, Wei-Chen Lee, Yi-Yin Jan and Miin-Fu Chen

    Citation: BMC Gastroenterology 2018 18:180

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  22. Content type: Research article

    Acute decompensation (AD) has been shown to be associated with a high mortality rate for cirrhosis patients. This study aimed to develop a prognostic nomogram to evaluating the individual prognosis for AD of c...

    Authors: Fangyuan Gao, Xiaoshu Li, Gang Wan, Yuxin Li, Qun Zhang, Yao Liu, Huimin Liu, Hai Li and Xianbo Wang

    Citation: BMC Gastroenterology 2018 18:179

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  23. Content type: Research article

    The estimation of the burden of disease attributable to fatty liver requires studies performed in the general population.

    Authors: Francesco Giuseppe Foschi, Giorgio Bedogni, Marco Domenicali, Pierluigi Giacomoni, Anna Chiara Dall’Aglio, Francesca Dazzani, Arianna Lanzi, Fabio Conti, Sara Savini, Gaia Saini, Mauro Bernardi, Pietro Andreone, Amalia Gastaldelli, Andrea Casadei Gardini, Claudio Tiribelli, Stefano Bellentani…

    Citation: BMC Gastroenterology 2018 18:177

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  24. Content type: Research article

    Laparoscopic liver resection has been regarded as the standard treatment for liver tumors located at the left lateral liver sector. However, few studies have reported the results of laparoscopic left lateral s...

    Authors: Chao-Wei Lee, Hsin-I Tsai, Hao-Tsai Cheng, Wei-Ting Chen, Heng-Yuan Hsu, Chien-Chih Chiu, Yi-Ping Liu, Tsung-Han Wu, Ming-Chin Yu, Wei-Chen Lee and Miin-Fu Chen

    Citation: BMC Gastroenterology 2018 18:178

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  25. Content type: Research article

    Delayed gastric emptying (DGE) is one of the most frequent complications following pancreaticoduodenectomy. This meta-analysis aimed to evaluate the impact of Braun enteroenterostomy on DGE following pancreati...

    Authors: Yanming Zhou, Bin Hu, Kongyuan Wei and Xiaoying Si

    Citation: BMC Gastroenterology 2018 18:176

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  27. Content type: Research article

    Hepatic arterioportal shunt (A-P shunt) is defined as the direct blood flow established between hepatic artery and portal venous system; it is frequently observed in patients with hepatocellular carcinoma (HCC...

    Authors: Huiyong Wu, Wei Zhao, Jianbo Zhang, Jianjun Han and Shuguang Liu

    Citation: BMC Gastroenterology 2018 18:174

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  29. Content type: Research article

    Associations between colorectal cancer and microbiota have been identified. Archived fecal samples might be valuable sample sources for investigating causality in carcinogenesis and biomarkers discovery due to...

    Authors: Trine B. Rounge, Roger Meisal, Jan Inge Nordby, Ole Herman Ambur, Thomas de Lange and Geir Hoff

    Citation: BMC Gastroenterology 2018 18:171

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  30. Content type: Research article

    Chronic autoimmune atrophic gastritis (CAAG) is an autoimmune disease characterized by hypo/achlorhydria. A role of CAAG in the pathogenesis of nutritional deficiencies has been reported, therefore we hypothes...

    Authors: Sara Massironi, Federica Cavalcoli, Alessandra Zilli, Alessandro Del Gobbo, Clorinda Ciafardini, Susanna Bernasconi, Irene Felicetta, Dario Conte and Maddalena Peracchi

    Citation: BMC Gastroenterology 2018 18:172

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  31. Content type: Research article

    The adequacy of pre-procedure preparation is the principal determinant of the quality of colonoscopy in pediatric as in adult patients. There is a lack of consensus, among providers on a standard pre-procedure...

    Authors: Ashwath S. Kumar, Brooke L. Beutler and Thomas M. Attard

    Citation: BMC Gastroenterology 2018 18:170

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  32. Content type: Research article

    Alterations of the small-intestinal permeability (s-IP) might play an essential role in both diarrhoea-predominant IBS (D-IBS) and celiac disease (CD) patients. Our aims were to analyse in D-IBS patients the s...

    Authors: Michele Linsalata, Giuseppe Riezzo, Benedetta D’Attoma, Caterina Clemente, Antonella Orlando and Francesco Russo

    Citation: BMC Gastroenterology 2018 18:167

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  33. Content type: Research article

    Patients with potentially resectable pancreatic ductal adenocarcinoma (PDAC) are frequently found to be unresectable on exploration due to small distant metastasis. This study was to investigate predictors of ...

    Authors: Xinchun Liu, Yue Fu, Qiuyang Chen, Junli Wu, Wentao Gao, Kuirong Jiang, Yi Miao and Jishu Wei

    Citation: BMC Gastroenterology 2018 18:168

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  34. Content type: Research article

    Clinical severity and intestinal lesions of Crohn’s disease (CD) usually progress over time and require a step up adjustment of the therapy either to prevent or to treat complications. The aim of the study was...

    Authors: Nadia Pallotta, Giuseppina Vincoli, Patrizio Pezzotti, Maurizio Giovannone, Alessandro Gigliozzi, Danilo Badiali, Piero Vernia and Enrico Stefano Corazziari

    Citation: BMC Gastroenterology 2018 18:164

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  35. Content type: Research article

    The incidence of liver-related events, cardiovascular events and type 2 diabetes mellitus in patients with histopathologically confirmed NAFLD remains unclear.

    Authors: Norio Akuta, Yusuke Kawamura, Yasuji Arase, Satoshi Saitoh, Shunichiro Fujiyama, Hitomi Sezaki, Tetsuya Hosaka, Masahiro Kobayashi, Mariko Kobayashi, Yoshiyuki Suzuki, Fumitaka Suzuki, Kenji Ikeda and Hiromitsu Kumada

    Citation: BMC Gastroenterology 2018 18:165

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  36. Content type: Research article

    Cholangiocarcinoma (CCA) is a form of cancer that easily aggress to contiguous structures. Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2) are increased in majority species of cancers an...

    Authors: Manping Huang, Bin Huang, Guowen Li and Sainan Zeng

    Citation: BMC Gastroenterology 2018 18:169

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  37. Content type: Research article

    Endoscopic retrograde cholangiopancreatography (ERCP) often requires deep sedation. Dexmedetomidine, a highly selective α2-adrenoceptor agonist with sedative activity and minimal effects on respiration, has re...

    Authors: Osamu Inatomi, Takayuki Imai, Takehide Fujimoto, Kenichiro Takahashi, Yoshihiro Yokota, Noriaki Yamashita, Hiroshi Hasegawa, Atsushi Nishida, Shigeki Bamba, Mitsushige Sugimoto and Akira Andoh

    Citation: BMC Gastroenterology 2018 18:166

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  38. Content type: Case report

    Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most frequently performed procedures for the treatment of biliary-pancreatic diseases. The most frequent complications of ERCP include pancre...

    Authors: Yangbei Zhu, Shuling Wang, Shengbing Zhao, Lin Qi, Zhaoshen Li and Yu Bai

    Citation: BMC Gastroenterology 2018 18:163

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  39. Content type: Case report

    The diagnosis of Coeliac disease (CD) requires a combination of sign/symptoms, positivity of specific antibodies and duodenal histological evidence of villous atrophy. Duodenal villous atrophy, despite represe...

    Authors: Vito Domenico Corleto, Vincenza Patrizia Di Marino, Gloria Galli, Giulio Antonelli, Chiara Coluccio, Arcangelo Di Cerbo, Stefania Uccini and Bruno Annibale

    Citation: BMC Gastroenterology 2018 18:162

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  40. Content type: Research article

    Gallbladder Polyps (GBP) are highly prevalent in China; however, the etiology of GBP has not been clearly defined. This study explored the associations between lifestyle factors and GBP and whether it mediated...

    Authors: Song Leng, Ai Zhao, Qiang Li, Leilei Pei, Wei Zheng, Rui Liang and Hong Yan

    Citation: BMC Gastroenterology 2018 18:159

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  42. Content type: Research article

    Macrocytic anemia is common in liver disease. However, its role in hepatitis B virus (HBV)-related decompensated cirrhosis remains unknown. The aim of the present study was to determine the association between...

    Authors: Jian Yang, Bin Yan, Lihong Yang, Huimin Li, Yajuan Fan, Feng Zhu, Jie Zheng and Xiancang Ma

    Citation: BMC Gastroenterology 2018 18:161

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  43. Content type: Research article

    The elderly population presents higher morbidity of H. pylori associated diseases in proximal stomach. The specific pathogenesis and mechanism have not been clearly addressed. The gastric environment for H. pylor...

    Authors: Huiying Shi, Hanhua Xiong, Wei Qian and Rong Lin

    Citation: BMC Gastroenterology 2018 18:158

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  44. Content type: Research article

    Advanced pancreatic cancer is accompanied not only by bile duct obstruction, but also occasionally by duodenal obstruction. With new advances in chemotherapy and improvement in the management of stent dysfunct...

    Authors: Kazuyuki Matsumoto, Hironari Kato, Shigeru Horiguchi, Koichiro Tsutsumi, Yosuke Saragai, Saimon Takada, Sho Mizukawa, Shinichiro Muro, Daisuke Uchida, Takeshi Tomoda and Hiroyuki Okada

    Citation: BMC Gastroenterology 2018 18:157

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  47. Content type: Research article

    Symptom based referral criteria for colorectal cancer (CRC) detection are the cornerstone of the strategy to improve prognosis in CRC. In 2017, the National Institute for Health and Care Excellence (NICE) upda...

    Authors: Jesús-Miguel Herrero, Pablo Vega, María Salve, Luis Bujanda and Joaquín Cubiella

    Citation: BMC Gastroenterology 2018 18:155

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  49. Content type: Research article

    Gastrointestinal complications are the main cause of death in patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Available treatments often restore biochemical homeostasis, but fail t...

    Authors: Rana Yadak, Max V. Boot, Niek P. van Til, Dominique Cazals-Hatem, Armin Finkenstedt, Elly Bogaerts, Irenaeus F. de Coo and Marianna Bugiani

    Citation: BMC Gastroenterology 2018 18:149

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  50. Content type: Research article

    Perioperative serum potassium levels are closely associated with postoperative clinical outcomes after gastrointestinal surgery. The aim of our retrospective study was to identify the prevalence and risk facto...

    Authors: Qianqian Zhu, Xianlong Li, Fang Tan, Yingqing Deng, Chulian Gong, Jingping Hu, Pinjie Huang and Shaoli Zhou

    Citation: BMC Gastroenterology 2018 18:152

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