Articles
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Citation: BMC Gastroenterology 2022 22:386
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Fully covered self-expandable metal stent for intraprocedural or late-diagnosed Type-II endoscopic retrograde cholangiopancreatography-related perforations
Perforations related to endoscopic retrograde cholangiopancreatography (ERCP) are rare but life-threatening complications. The treatment of Type-II-periampullary perforations that develop during endoscopic sph...
Citation: BMC Gastroenterology 2022 22:385 -
Feasibility of quantification based on novel evaluation with stool DNA and fecal immunochemical test for colorectal cancer detection
Stool DNA (sDNA) tests and fecal immunochemical test (FIT) are used for the detection of colorectal cancer (CRC). Here we performed a novel evaluation using sDNA and FIT to assess their performance in CRC scre...
Citation: BMC Gastroenterology 2022 22:384 -
The CHAMP-study: the CHemopreventive effect of lithium in familial AdenoMatous Polyposis; study protocol of a phase II trial
Familial adenomatous polyposis (FAP) is a rare autosomal dominant disease characterized by germline mutations in the Adenomatous Polyposis Coli (APC) gene, resulting in the development of numerous colorectal aden...
Citation: BMC Gastroenterology 2022 22:383 -
Effect of ice water injection toward the duodenal papilla for preventing post-ERCP pancreatitis: study protocol for a multicenter, single-blinded, randomized controlled trial (EUTOPIA study)
Endoscopic retrograde cholangiopancreatography (ERCP) is an essential procedure in the diagnosis and treatment of biliopancreatic diseases. The most common adverse event of ERCP is post-ERCP pancreatitis (PEP)...
Citation: BMC Gastroenterology 2022 22:382 -
Consolidative chemotherapy after definitive concurrent chemoradiotherapy for esophageal squamous cell carcinoma patients: a population based cohort study
The role of consolidative chemotherapy (CCT) for locally advanced esophageal squamous cell carcinoma (LA-ESCC) patients treated with definitive concurrent chemoradiotherapy (dCCRT) is unclear. We aimed to comp...
Citation: BMC Gastroenterology 2022 22:381 -
Expression of unfolded protein response genes in post-transplantation liver biopsies
Cholestatic liver diseases are a major source of morbidity and mortality that can progress to end-stage liver disease and hyperbilirubinemia is a hallmark of cholestasis. There are few effective medical therap...
Citation: BMC Gastroenterology 2022 22:380 -
Comparison of anal dilatation versus no dilatation with a standardized dilator in reducing pain after hemorrhoidectomy: a randomized control trial
Post-operative pain is the main problem of hemorrhoidectomy. An adequate pain management can promote early mobilization, fast recovery, and reduce hospitalization costs. This study aimed to investigate the rol...
Citation: BMC Gastroenterology 2022 22:379 -
The upregulation of stromal antigen 3 expression suppresses the phenotypic hallmarks of hepatocellular carcinoma through the Smad3-CDK4/CDK6-cyclin D1 and CXCR4/RhoA pathways
The stromal antigen 3 (STAG3) gene encodes an adhesion complex subunit that can regulate sister chromatid cohesion during cell division. Chromosome instability caused by STAG3 gene mutation may potentially pro...
Citation: BMC Gastroenterology 2022 22:378 -
Natural history of intracholecystic papillary neoplasm (ICPN): a rare case of ICPN whose natural history was closely followed by ultrasound
The natural history of intracholecystic papillary neoplasm (ICPN), especially the speed of growth from small benign to a carcinomatous lesion, is quite unrevealed. Here, we report an extremely rare case of ICP...
Citation: BMC Gastroenterology 2022 22:377 -
EUS-guided fine needle aspiration provides an open view for duodenal obstruction caused by urothelial carcinoma: a case report
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a good alternative and diagnostic tool for gastrointestinal wall thickening with prior negative endoscopic biopsies.
Citation: BMC Gastroenterology 2022 22:376 -
Serum and salivary tissue transglutaminase IGA (tTG-IGA) level in celiac patients
Celiac disease (CD) is a genetically determined autoimmune disease triggered by gluten consumption. Patients with these conditions have intraepithelial lymphocytosis, crypt hyperplasia, and severe intestinal a...
Citation: BMC Gastroenterology 2022 22:375 -
Awareness and treatment of chronic hepatitis B in Malaysia-findings from a community-based screening campaign
In 2016 the World Health Organization (WHO) had adopted a global strategy to eliminate Hepatitis B (HBV) by 2030 through five core interventions. One of which is the “cascade of care”, the continuum of service...
Citation: BMC Gastroenterology 2022 22:374 -
Indocyanine green fluorescence imaging localization-assisted thoracoscopy revision surgery after repair of esophageal atresia
Revision surgery for the complications after repair of esophageal atresia is often complex because of previous surgeries and chest infections and thus requires surgical expertise. This study describes surgical...
Citation: BMC Gastroenterology 2022 22:373 -
Alterations of liver enzymes and lipid profile in response to exhaustive eccentric exercise: vitamin D supplementation trial in overweight females with non-alcoholic fatty liver disease
Eccentric exhaustive exercise (EEE) training has been known as a promising training modality to enhance performance and stimulate adaptation in healthy individuals or patients that might also cause abnormal li...
Citation: BMC Gastroenterology 2022 22:372 -
Surgery for acute cholecystitis in severely comorbid patients: a population-based study on acute cholecystitis
International guidelines recommend emergency cholecystectomy for acute cholecystitis in patients who are healthy or have mild systemic disease (ASA1-2). Surgery is also an option for patients with severe syste...
Citation: BMC Gastroenterology 2022 22:371 -
Use of folic acid supplementation to halt and even reverse the progression of gastric precancerous conditions: a meta-analysis
Current data indicate that supplements such as folic acid and vitamin B may be beneficial in halting and even reversing atrophic gastritis, intestinal metaplasia and intraepithelial neoplasia, generally referr...
Citation: BMC Gastroenterology 2022 22:370 -
Clinical and imaging features preoperative evaluation of histological grade and microvascular infiltration of hepatocellular carcinoma
To predict the histological grade and microvascular invasion (MVI) in patients with HCC.
Citation: BMC Gastroenterology 2022 22:369 -
Nomogram for predicting rebleeding after initial endoscopic epinephrine injection monotherapy hemostasis in patients with peptic ulcer bleeding: a retrospective cohort study
Although the current guidelines recommend endoscopic combination therapy, endoscopic epinephrine injection (EI) monotherapy is still a simple, common and effective modality for treating peptic ulcer bleeding (...
Citation: BMC Gastroenterology 2022 22:368 -
Nonsteroidal anti-inflammatory drug exposure and the risk of microscopic colitis
Medication consumption has been suggested as a risk factor for microscopic colitis (MC), but studies of varying design have yielded inconsistent results. Our aim was to evaluate the association between medicat...
Citation: BMC Gastroenterology 2022 22:367 -
The prevalence of alcoholic and nonalcoholic fatty liver disease in adolescents and young adults in the United States: analysis of the NHANES database
The prevalence of fatty liver disease is potentially increasing in adolescents and young adults (AYAs) due to the obesity and alcohol pandemics. The aim of this study was to assess the prevalence of alcohol-as...
Citation: BMC Gastroenterology 2022 22:366 -
Subcutaneous administration, higher age and lower renal function are associated with erythrocyte methotrexate accumulation in Crohn’s disease: a cross-sectional study
Methotrexate is an immunomodulatory drug for patients with Crohn’s disease. Erythrocyte MTX-polyglutamates (MTX-PG1-5) may be used for therapeutic drug monitoring (TDM) as MTX-PG is thought to mediate MTX’s effic...
Citation: BMC Gastroenterology 2022 22:365 -
Metabolism reprogramming signature associated with stromal cells abundance in tumor microenvironment improve prognostic risk classification for gastric cancer
Stromal cells play an important role in the process of tumor progression, but the relationship between stromal cells and metabolic reprogramming is not very clear in gastric cancer (GC).
Citation: BMC Gastroenterology 2022 22:364 -
Portal flow diversion based on portography is superior than puncture site in the prediction of overt hepatic encephalopathy after TIPS creation
Targeted puncture of an appropriate portal venous branch during transjugular intrahepatic portosystemic shunt (TIPS) procedure may reduce the risk of postprocedural overt hepatic encephalopathy (HE). This stud...
Citation: BMC Gastroenterology 2022 22:363 -
Establishing correlations between normal pancreatic and submandibular gland ducts
The objectives of this study were to evaluate the relationship between ductal morphometry and ramification patterns in the submandibular gland and pancreas in order to validate their common fractal dimension.
Citation: BMC Gastroenterology 2022 22:362 -
Mortality and complications after percutaneous endoscopic gastrostomy: a retrospective multicentre study
Percutaneous endoscopic gastrostomy (PEG) is the method of choice for patients in need of long-term nutritional support or gastric decompression. Although it is considered safe, complications and relatively hi...
Citation: BMC Gastroenterology 2022 22:361 -
Gastric carcinosarcoma with FGFR2 amplification under long-term control with pazopanib: a case report and literature review
Gastric carcinosarcoma is most frequently diagnosed at an advanced stage when the tumor is generally large with invasion into other organs, lymph node metastasis, and distant metastasis. Standard chemotherapy ...
Citation: BMC Gastroenterology 2022 22:360 -
Total neoadjuvant therapy for locally advanced gastric cancer and esophagogastric junction adenocarcinoma: study protocol for a prospective, multicenter, single-arm, phase II clinical trial
Gastric cancer ranks high in terms of morbidity and mortality worldwide. Multimodal therapy is therefore essential for locally advanced gastric cancer. Recent studies have demonstrated that both perioperative ...
Citation: BMC Gastroenterology 2022 22:359 -
Association of serum creatinine with hepatic steatosis and fibrosis: a cross-sectional study
Recent studies have shown that chronic kidney disease (CKD) prevalence is significantly higher in patients with hepatic steatosis (HS); however, it remains unclear whether HS is associated with serum creatinin...
Citation: BMC Gastroenterology 2022 22:358 -
Situs inversus totalis with local metastasis of gallbladder carcinoma and variation of the common hepatic artery
Situs inversus totalis (SIT) is a rare congenital anomaly characterized by a complete transposition of all the viscera. SIT cases were usually reported because of the presence of tumors, leading to false assoc...
Citation: BMC Gastroenterology 2022 22:357 -
Correction to: Real-world characteristics, treatment experiences and corticosteroid utilisation of patients treated with tofacitinib for moderate to severe ulcerative colitis
Citation: BMC Gastroenterology 2022 22:356 -
Endoscopic variceal obturation and retrograde transvenous obliteration for acute gastric cardiofundal variceal bleeding in liver cirrhosis
We retrospectively compared the effect of endoscopic variceal obturation (EVO) and retrograde transvenous obliteration (RTO) in acute cardiofundal variceal bleeding.
Citation: BMC Gastroenterology 2022 22:355 -
Value of contrast-enhanced ultrasound in diagnosis and differential diagnosis of polypoid lesions of gallbladder ≥ 1 cm
To evaluate the usefulness of Contrast-enhanced ultrasound (CEUS) in the diagnosis and differential diagnosis of Polypoid lesions of gallbladder (PLGs) ≥ 1 cm.
Citation: BMC Gastroenterology 2022 22:354 -
Comparison of risk scoring systems for upper gastrointestinal bleeding in patients after renal transplantation: a retrospective observational study in Hunan, China
Upper gastrointestinal bleeding (UGIB) is a common complication in renal transplant recipients. However, the risk stratification value of bleeding scoring systems in these patients is unclear, and data regardi...
Citation: BMC Gastroenterology 2022 22:353 -
Deep learning as a novel method for endoscopic diagnosis of chronic atrophic gastritis: a prospective nested case–control study
Chronic atrophic gastritis (CAG) is a precancerous disease that often leads to the development of gastric cancer (GC) and is positively correlated with GC morbidity. However, the sensitivity of the endoscopic ...
Citation: BMC Gastroenterology 2022 22:352 -
Current status of and barriers to the treatment of advanced-stage liver cancer in China: a questionnaire-based study from the perspective of doctors
Liver cancer is a severe public health problem worldwide, and it creates a relatively higher disease burden in China than in the Western world. Despite achieving notable progress in China, potential difference...
Citation: BMC Gastroenterology 2022 22:351 -
Effects of endoscopic injection sclerotherapy for esophagogastric varices on portal hemodynamics and liver function
To identify patients suitable for endoscopic injection sclerotherapy (EIS) by evaluating their portal hemodynamics and liver function.
Citation: BMC Gastroenterology 2022 22:350 -
Segmental reversal of the distal small intestine in a short bowel syndrome model in piglets showed detrimental effect on weight gain
To investigate the effects of a reversed segment of the distal small intestine to improve weight gain in an experimental short bowel syndrome (SBS) model in piglets.
Citation: BMC Gastroenterology 2022 22:349 -
Risk factors and predictive nomograms for early death of patients with advanced hepatocellular carcinoma: a large retrospective study based on the SEER database
Hepatocellular carcinoma (HCC) is a kind of tumor with high invasiveness, and patients with advanced HCC have a higher risk of early death. The aim of the present study was to identify the risk factors of earl...
Citation: BMC Gastroenterology 2022 22:348 -
A dynamic predictive nomogram of long-term survival in primary gastric lymphoma: a retrospective study
Primary gastric lymphoma (PGL) is the most common extranodal non-Hodgkin lymphoma (NHL). Due to the rarity of the disease, it is important to create a predictive model that provides treatment and prognosis for...
Citation: BMC Gastroenterology 2022 22:347 -
Epstein–Barr virus-associated gastric adenosquamous carcinoma with concurrent gastric carcinoma with lymphoid stroma: a case report and review of the literature
Adenosquamous carcinoma (ASC)with concurrent gastric carcinoma with lymphoid stroma (GCLS) are extremely rare tumors. There are only limited cases reported in the literature. Epstein–Barr virus (EBV) infection...
Citation: BMC Gastroenterology 2022 22:346 -
Construction of a novel necroptosis-related lncRNA signature for prognosis prediction in esophageal cancer
Esophageal cancer (EC), one highly malignant gastrointestinal cancer, is the 6th leading cause of cancer-related deaths worldwide. Necroptosis and long non-coding RNA (lncRNA) play important roles in the occur...
Citation: BMC Gastroenterology 2022 22:345 -
Identification and validation of necroptosis-related prognostic gene signature and tumor immune microenvironment infiltration characterization in esophageal carcinoma
Esophageal carcinoma (ESCA) is a common malignancy with a poor prognosis. Previous research has suggested that necroptosis is involved in anti-tumor immunity and promotes oncogenesis and cancer metastasis, whi...
Citation: BMC Gastroenterology 2022 22:344 -
Endoscopic ultrasonography guided cutting scar of esophageal stricture after endoscopic injection sclerotherapy
To investigate efficacy and safety of endoscopic ultrasonography (EUS) guiding to cut the scar of esophageal stricture after endoscopic injection sclerotherapy (EIS).
Citation: BMC Gastroenterology 2022 22:343 -
Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan
Fecal microbiota transplantation (FMT) is a potential treatment for irritable bowel syndrome (IBS), but its efficacy in Japanese IBS patients is unknown. This study aimed to evaluate the efficacy, side effects...
Citation: BMC Gastroenterology 2022 22:342 -
Study protocol of a single-arm phase 2 study evaluating the preventive effect of topical hydrocortisone for capecitabine-induced hand-foot syndrome in colorectal cancer patients receiving adjuvant chemotherapy with capecitabine plus oxaliplatin (T-CRACC study)
Clinical evidence of the preventive effectiveness of medium-class topical corticosteroids for capecitabine-induced hand foot syndrome (HFS) is limited. Although the pathogenesis and mechanism of HFS are unclea...
Citation: BMC Gastroenterology 2022 22:341 -
Poor disease knowledge is associated with higher healthcare service use and costs among patients with cirrhosis: an exploratory study
Optimal management of cirrhosis is complex, and patients often lack knowledge and skills, which can affect self-management. We assessed patient knowledge about cirrhosis and examined whether knowledge was asso...
Citation: BMC Gastroenterology 2022 22:340 -
Hepatitis C treatment outcomes for Australian First Nations Peoples: equivalent SVR rate but higher rates of loss to follow-up
First Nations Peoples of Australia are disproportionally affected by hepatitis C (HCV) infection. Through a prospective study we evaluated the outcome of direct-acting antiviral (DAA) therapy among First Natio...
Citation: BMC Gastroenterology 2022 22:339 -
Establishment and evaluation of a nomogram predicting risks of missed diagnoses of colorectal polyps
A missed diagnosis of colorectal polyps during colonoscopy may be associated with the occurrence of interval colorectal cancer. The risk factors for a missed diagnosis or a method to predict the risk of a miss...
Citation: BMC Gastroenterology 2022 22:338 -
Prediction of the need for emergency endoscopic treatment for upper gastrointestinal bleeding and new score model: a retrospective study
Gastrointestinal bleeding is one of the major gastrointestinal diseases. In this study, our objective was to compare Glasgow-Blatchford score (GBS), AIMS65 score, MAP score, Modified GBS, and Iino score as out...
Citation: BMC Gastroenterology 2022 22:337
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