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  1. Hyperprogressive disease (HPD) is a phenomenon with greatly accelerated tumor growth and clinical deterioration rates compared to pre-therapy, in patients treated with immune checkpoint inhibitors (ICI). The a...

    Authors: Sae Yumita, Sadahisa Ogasawara, Miyuki Nakagawa, Susumu Maruta, Tomomi Okubo, Norio Itokawa, Yotaro Iino, Masamichi Obu, Yuki Haga, Atsuyoshi Seki, Tadayoshi Kogure, Takamasa Ishino, Keita Ogawa, Kisako Fujiwara, Terunao Iwanaga, Naoto Fujita…
    Citation: BMC Gastroenterology 2023 23:101
  2. Crohn’s disease (CD) is associated with altered body composition, affecting clinical outcomes. We evaluated the impact of biologics on body composition in CD patients.

    Authors: Eun Jeong Choi, Dong Hoon Baek, Hong Sub Lee, Geun Am Song, Tae Oh Kim, Yong Eun Park, Chang Min Lee and Jong Hoon Lee
    Citation: BMC Gastroenterology 2023 23:100
  3. Colonic diverticulitis is a leading cause of abdominal pain. The monocyte distribution width (MDW) is a novel inflammatory biomarker with prognostic significance for coronavirus disease and pancreatitis; howev...

    Authors: Chang-Yuan Chang, Tai-Yi Hsu, Guan-Yi He, Hong-Mo Shih, Shih-Hao Wu, Fen-Wei Huang, Pei-Chun Chen and Wen-Chen Tsai
    Citation: BMC Gastroenterology 2023 23:96
  4. Evidence indicates that inflammation in Inflammatory Bowel Disease (IBD) is associated with increased systemic levels of reactive oxygen species. Systemic oxidative stress has been associated with reduced leve...

    Authors: Rebeca Araujo Passos, Priscila Ribas Farias Costa, Claudia Feio da Maia Lima, George Mariane Soares Santana, Victor David, Geisa de Jesus Santos, Cyrla Zaltman, Marcia Soares-Mota and Raquel Rocha
    Citation: BMC Gastroenterology 2023 23:94
  5. The clinicopathological features and endoscopic characteristics under magnifying endoscopy with narrow band imaging (ME-NBI) between early-stage gastric-type differentiated adenocarcinoma (GDA) and intestinal-...

    Authors: Borui Li, Tingting Chen, Dingbao Liang, Yin Zhang, Xiwei Ding and Ying Lv
    Citation: BMC Gastroenterology 2023 23:92
  6. To evaluate the impact of cholangitis on survival of patients with gastrointestinal cancer and malignant biliary obstruction treated with percutaneous transhepatic biliary drainage (PTBD).

    Authors: Jarmo Niemelä, Raija Kallio, Pasi Ohtonen, Juha Saarnio and Hannu Syrjälä
    Citation: BMC Gastroenterology 2023 23:91
  7. Non-alcoholic fatty liver disease (NAFLD) is associated with a greater risk of developing cardiovascular disease and have adverse impacts on the cardiac structure and function. Little is known about the effect...

    Authors: Fangyuan Cong, Luying Zhu, Lihua Deng, Qian Xue and Jingtong Wang
    Citation: BMC Gastroenterology 2023 23:90
  8. This study aims to construct and verify a nomogram model for microvascular invasion (MVI) based on hepatocellular carcinoma (HCC) tumor characteristics and differential protein expressions, and explore the cli...

    Authors: Zhenglu Wang, Lei Cao, Jianxi Wang, Hanlin Wang, Tingting Ma, Zhiqi Yin, Wenjuan Cai, Lei Liu, Tao Liu, Hengde Ma, Yamin Zhang, Zhongyang Shen and Hong Zheng
    Citation: BMC Gastroenterology 2023 23:89
  9. Systemic inflammation is recognized as a hallmark of cancer that contributes to tumor development and progression in various malignancies. The Naples prognostic score (NPS) was established as a prognostic indi...

    Authors: Atsushi Sugimoto, Tatsunari Fukuoka, Masatsune Shibutani, Hiroaki Kasashima, Kishu Kitayama, Masaichi Ohira and Kiyoshi Maeda
    Citation: BMC Gastroenterology 2023 23:88
  10. Crohn’s disease (CD) is a chronic inflammatory bowel disease characterized by relapsing and remitting inflammation that leads to progressive bowel damage. Despite advances in medical treatment for CD, many pat...

    Authors: Michelle Vu, Sabyasachi Ghosh, Kandavadivu Umashankar, Laura Weber, Christina Landis, Ninfa Candela and Benjamin Chastek
    Citation: BMC Gastroenterology 2023 23:87
  11. Acute-on-chronic liver failure (ACLF) is a critical illness with high mortality. Herein, we developed and validated a new and simple prognostic nomogram to predict 90-day mortality in hepatitis B virus-related...

    Authors: Ye Xiong, Zuoxun Xia, Lu Yang and Jianrong Huang
    Citation: BMC Gastroenterology 2023 23:86
  12. The Value of Golgi protein 73 (GP73) in the diagnosis of Hepatocellular carcinoma (HCC) remains controversial, especially in its differentiation between HCC and cirrhosis. Besides, some papers showed that GP73...

    Authors: Xu Zhang, Li-Na Wu, Xiao-Qing Li, Xia Luo, Shui-Wei Liu, Le Zhang, Shah Nawaz, Li-Na Ma and Xiang-Chun Ding
    Citation: BMC Gastroenterology 2023 23:85
  13. The National Comprehensive Cancer Network guidelines recommend routine postoperative adjuvant radiotherapy and chemotherapy for patients with stage III rectal cancer who do not receive neoadjuvant therapy befo...

    Authors: Jin-hu Chen, Qing Ye and Feng Huang
    Citation: BMC Gastroenterology 2023 23:83
  14. Rifaximin effectively treats symptomatic uncomplicated diverticular disease (SUDD) and has shown eubiotic potential (i.e., an increase in resident microbial elements with potential beneficial effects) in other...

    Authors: Vladimir Ivashkin, Oleg Shifrin, Roman Maslennikov, Elena Poluektova, Alexander Korolev, Anna Kudryavtseva, George Krasnov, Nona Benuni and Giovanni Barbara
    Citation: BMC Gastroenterology 2023 23:82
  15. The impact of pre-existing comorbidities on acute pancreatitis (AP) mortality is not clearly defined. Our study aims to determine the trend in AP hospital mortality and the role of comorbidities as a predictor...

    Authors: Nils Jimmy Hidalgo, Elizabeth Pando, Rodrigo Mata, Nair Fernandes, Sara Villasante, Marta Barros, Daniel Herms, Laia Blanco, Joaquim Balsells and Ramon Charco
    Citation: BMC Gastroenterology 2023 23:81
  16. To evaluate the prognostic value of the pre-treatment aspartate transaminase (AST)/alanine transaminase (ALT) ratio in hepatocellular carcinoma (HCC) patients receiving radiofrequency ablation (RFA)/microwave ...

    Authors: Feihang Wang, Shanshan Gao, Mengfei Wu, Danyang Zhao, Huiyi Sun, Sothea Yav, Yi Chen, Zihan Zhang, Minjie Yang, Yi Dong, Jianhua Wang, Xiaolin Wang, Zhiping Yan and Lingxiao Liu
    Citation: BMC Gastroenterology 2023 23:80
  17. Glucagon-like peptide-2 (GLP-2) enhances intestinal repair and attenuates inflammation in preclinical inflammatory bowel disease (IBD) models, making GLP-2 analogues attractive candidates for IBD therapy. Glep...

    Authors: Jolanta Skarbaliene, Jesper Mosolff Mathiesen, Bjarne Due Larsen, Christian Thorkildsen and Yvette Miata Petersen
    Citation: BMC Gastroenterology 2023 23:79
  18. Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. Ultrasound, the most used tool for diagnosing NAFLD, is operator-dependent and shows suboptimal performance in patients with...

    Authors: Ha Neul Kim, Hong Jae Jeon, Hei Gwon Choi, In Sun Kwon, Woo Sun Rou, Jeong Eun Lee, Tae Hee Lee, Seok Hyun Kim, Byung Seok Lee, Kyung Sook Shin, Hyun Jung Lee and Hyuk Soo Eun
    Citation: BMC Gastroenterology 2023 23:77
  19. Complete and consecutive observation of the gastrointestinal (GI) tract continues to present challenges for current endoscopy systems. We developed a novel upper and mid gastrointestinal (UMGI) capsule endosco...

    Authors: Bin Jiang, Yang-Yang Qian, Yuan-Chen Wang, Jun Pan, Xi Jiang, Jia-Hui Zhu, Xiao-Ou Qiu, Wei Zhou, Zhao-Shen Li and Zhuan Liao
    Citation: BMC Gastroenterology 2023 23:76
  20. Primary sclerosing cholangitis (PSC) is a chronic progressive liver disease leading to biliary fibrosis and cirrhosis. Cilofexor is a nonsteroidal farnesoid X receptor agonist that demonstrated significant imp...

    Authors: Michael Trauner, Chuhan Chung, Kate Sterling, Xiangyu Liu, Xiaomin Lu, Jun Xu, Clare Tempany-Afdhal, Zachary D. Goodman, Martti Färkkilä, Atsushi Tanaka, Palak Trivedi, Kris V. Kowdley, Christopher L. Bowlus, Cynthia Levy and Robert P. Myers
    Citation: BMC Gastroenterology 2023 23:75
  21. Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn’s disease and ul...

    Authors: Severin A. Lautenschlager, Mamadou Pathé Barry, Gerhard Rogler, Luc Biedermann, Philipp Schreiner and Alexander R. Siebenhüner
    Citation: BMC Gastroenterology 2023 23:71
  22. Ramucirumab was shown to be effective as a second-line treatment after sorafenib in patients with advanced hepatocellular carcinoma (HCC) with alpha-fetoprotein levels > 400 ng/mL in a worldwide phase 3 trial....

    Authors: Naoya Kanogawa, Sadahisa Ogasawara, Susumu Maruta, Yotaro Iino, Masamichi Obu, Takamasa Ishino, Keita Ogawa, Sae Yumita, Terunao Iwanaga, Hidemi Unozawa, Miyuki Nakagawa, Kisako Fujiwara, Takafumi Sakuma, Naoto Fujita, Ryuta Kojima, Hiroaki Kanzaki…
    Citation: BMC Gastroenterology 2023 23:70
  23. Although swallowing disorders can impact individuals of any age, some are unique to the elderly, and others are frequent. Some disorders, such as achalasia, are diagnosed by esophageal manometry studies, which...

    Authors: Ahmed Abdelghani, Alhosaeyn Ibrahim, El-Sayed El-Sayed, Mohammad El Sherbiny and Ahmed Al-Badry
    Citation: BMC Gastroenterology 2023 23:69
  24. A prognostic assessment method with good sensitivity and specificity plays an important role in the treatment of pancreatic cancer patients. Finding a way to evaluate the prognosis of pancreatic cancer is of g...

    Authors: Xuanfeng Zhang, Lulu Yang, Dong Zhang, Xiaochuan Wang, Xuefeng Bu, Xinhui Zhang and Long Cui
    Citation: BMC Gastroenterology 2023 23:68
  25. The prevalence, management, and clinical outcomes of cholangiocarcinoma in Africa are unknown. The aim is to conduct a comprehensive systematic review on the epidemiology, management, and outcomes of cholangio...

    Authors: Akwi W. Asombang, Nathaniel Chishinga, Mouhand F. Mohamed, Alick Nkhoma, Jackson Chipaila, Bright Nsokolo, Martha Manda-Mapalo, Joao Filipe G. Montiero, Lewis Banda and Kulwinder S. Dua
    Citation: BMC Gastroenterology 2023 23:66
  26. Current quantitative approaches to assess chronic liver disease (CLD) severity have limitations. Further, portal vein thrombosis (PVT) pre-liver transplant (LT) is a major contributor to morbidity in CLD; the ...

    Authors: Clayton S. Lewis, Khurram Bari, Changchun Xie, Kenneth E. Sherman, Marc Vasse, Patrick Van Dreden and Vladimir Y. Bogdanov
    Citation: BMC Gastroenterology 2023 23:65
  27. Neoadjuvant therapy favors the prognosis of various cancers, including esophagogastric junction cancer (EGC). However, the impacts of neoadjuvant therapy on the number of dissected lymph nodes (LNs) have not y...

    Authors: Qi Wang, Jin-tong Ge, Hua Wu, Sheng Zhong and Qing-quan Wu
    Citation: BMC Gastroenterology 2023 23:64
  28. The purpose of this analysis was to assess the frequency of inadequate response over 1 year from advanced therapy initiation among patients with Crohn’s disease (CD) or ulcerative colitis (UC) in the United St...

    Authors: Theresa Hunter Gibble, April N. Naegeli, Michael Grabner, Keith Isenberg, Mingyang Shan, Chia-Chen Teng and Jeffrey R. Curtis
    Citation: BMC Gastroenterology 2023 23:63
  29. This study aimed to compare the incidence, clinicopathological characteristics and survival results of pancreatic signet ring cell carcinoma (PSRCC) and pancreatic adenocarcinomas (PDAC), as well as to analyze...

    Authors: Duorui Nie, Jing Yang, Hao Zheng, Guihua Lai, Fei Wang, Jianxiong Cao and Chun Gong
    Citation: BMC Gastroenterology 2023 23:62
  30. Increased familiarity with capsule endoscopy (CE) has been associated with a growing demand for urgent inpatient procedures. Limited data exists comparing the effect of admission status on colon capsule (CCE) ...

    Authors: Charlene Deane, Caroline Walker, Barbara Ryan, Anthony O’Connor, Sarah O’Donnell, Niall Breslin and Deirdre McNamara
    Citation: BMC Gastroenterology 2023 23:61
  31. First-line treatment of eosinophilic esophagitis (EoE) includes monotherapy with proton-pump inhibitors (PPIs), food elimination diet (FED), or topical corticosteroids. Current guidelines suggest patients with...

    Authors: Twan Sia, Evan Cunningham, Megan Miller, Rebecca Nitschelm, Riki Tanaka, Taylor Epstein, Kendall Garrett, Amy Huang, Daniel Pak, Ally Scheve and John Leung
    Citation: BMC Gastroenterology 2023 23:60
  32. Surgical acute abdomen is a sudden onset of severe abdominal symptoms (pain, vomiting, constipation etc.) indicative of a possible life-threatening intra-abdominal pathology, with most cases requiring immediat...

    Authors: Maryam Hamdan, Xu Yang, M. Mavura, Mohammed Saleh, George Kannani, Kang Haonan, Abdullah Al-danakh, Xu Zhaohui, Gong Zezhong, Ri Hyokju, Boureima Amado, Ren Yanying and Chen Xin
    Citation: BMC Gastroenterology 2023 23:59
  33. Colon cancer is a common and highly malignant tumor. Its incidence is increasing rapidly with poor prognosis. At present, immunotherapy is a rapidly developing treatment for colon cancer. The aim of this study...

    Authors: Mengdi Hao, Huimin Li, Meng Yi, Yubing Zhu, Kun Wang, Yin Liu, Xiaoqing Liang and Lei Ding
    Citation: BMC Gastroenterology 2023 23:58
  34. Enteric fistula is one of the penetrating features in Crohn’s disease (CD). This study aimed to clarify the prognostic factors for the efficacy of infliximab (IFX) treatment in luminal fistulizing CD patients.

    Authors: Ye Ma, Runfeng Zhang, Wei Liu, Yinghao Sun, Jingnan Li, Hong Yang, Hong Lv, Yue Li, Bei Tan, Xiyu Sun, Jiaming Qian and Ji Li
    Citation: BMC Gastroenterology 2023 23:57
  35. Bowel gangrene represents a major fatal event in acute mesenteric ischemia. Intestinal resection is inevitable in patients with peritonitis and bowel gangrene. This retrospective study aimed to elucidate the b...

    Authors: Hsiao-Tien Liu, Chia-Yu Lai, Jian-Jhou Liao, Yi-Ju Chen, Shao-Bin Cheng and Cheng-Chung Wu
    Citation: BMC Gastroenterology 2023 23:56
  36. The effectiveness of Helicobacter pylori (H. pylori) eradication depends on the treatment protocol. This study investigates the H. pylori eradication rate in Africa using the best available evidence from database...

    Authors: Sintayehu Fekadu, Hizkel Engiso, Sisay Seyfe, Hisashi Iizasa, Ashebir Godebo, Serawit Deyno and Hironori Yoshiyama
    Citation: BMC Gastroenterology 2023 23:55
  37. The purpose of this research was to construct a novel predictive nomogram to identify specific stage IB gastric adenocarcinoma (GAC) populations who could benefit from postoperative adjuvant chemotherapy (ACT).

    Authors: Yangyang Xie, Xue Song, Danwei Du, Haimin Jin, Xiaowen Li, Zhongkai Ni and Hai Huang
    Citation: BMC Gastroenterology 2023 23:54
  38. Studies concerning the impact of air temperature on esophagogastric variceal bleeding (EGVB) have yielded conflicting results. Our study aimed to evaluate the correlation between air temperature and EGVB.

    Authors: Jianhong Chen, Ziting Wu, Hui Gao, Li Li, Yanling Wang, Jingjing Han, Chuan Zhang, Pengpeng Ding and Jing Wu
    Citation: BMC Gastroenterology 2023 23:52

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