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  1. Research article

    Partially covered metal stents have longer patency than uncovered and fully covered metal stents in the management of distal malignant biliary obstruction: a retrospective study

    Self-expandable metal stents (SEMSs) are widely used for malignant biliary obstructions. Nitinol-covered SEMSs have been developed to improve stent patency. Currently, SEMSs may be uncovered, partially covered...

    Yudai Yokota, Mitsuharu Fukasawa, Shinichi Takano, Makoto Kadokura, Hiroko Shindo, Ei Takahashi, Sumio Hirose, Satoshi Kawakami, Yoshimitsu Fukasawa, Tadashi Sato and Nobuyuki Enomoto

    BMC Gastroenterology 2017 17:105

    Published on: 11 October 2017

  2. Research article

    Association between polymorphisms of TAS2R16 and susceptibility to colorectal cancer

    Genetics plays an important role in the susceptibility to sporadic colorectal cancer (CRC). In the last 10 years genome-wide association studies (GWAS) have identified over 40 independent low penetrance polymo...

    Jonathan Barontini, Marco Antinucci, Sergio Tofanelli, Maurizio Cammalleri, Massimo Dal Monte, Federica Gemignani, Pavel Vodicka, Roberto Marangoni, Ludmila Vodickova, Juozas Kupcinskas, Veronika Vymetalkova, Asta Forsti, Federico Canzian, Angelika Stein, Victor Moreno, Nicola Mastrodonato…

    BMC Gastroenterology 2017 17:104

    Published on: 15 September 2017

  3. Research article

    Addition of nucleoside analogues to peg-IFNα-2a enhances virological response in chronic hepatitis B patients without early response to peg-IFNα-2a: a randomized controlled trial

    Current treatments for chronic hepatitis B (CHB) include pegylated interferon alpha (PEG-IFN-α) which is an immune modulator, and nucleos(t)ide analogs (NAs) which directly inhibit HBV DNA polymerase. With the...

    Yan Xu, Xu Wang, Zhenhua Liu, Changyu Zhou, Wenqian Qi, Jian Jiao, Fan Yu, Honghua Guo, Ping Zhao and Jiangbin Wang

    BMC Gastroenterology 2017 17:102

    Published on: 30 August 2017

  4. Research article

    Diminished accuracy of biomarkers of fibrosis in low replicative chronic hepatitis B

    We evaluated the diagnostic accuracy of aspartate aminotransferase (AST)-to-platelet ratio index (APRI), fibrosis-4 index (FIB-4), AST/alanine aminotransferase (ALT) ratio (AAR), and age-platelet index (API) f...

    Faisal M. Sanai, Taha Farah, Khalid Albeladi, Faisal Batwa, Yaser Dahlan, Mohammed A. Babatin, Hamad Al-Ashgar, Hadeel AlMana, Khaled S. Alsaad, Khalid AlSwat, Abdulrahman Aljumah, Ibrahim H. AlTraif, Bahaa E. Kailani and Khalid I. Bzeizi

    BMC Gastroenterology 2017 17:101

    Published on: 25 August 2017

  5. Research article

    Protective effects of heme oxygenase-1 against severe acute pancreatitis via inhibition of tumor necrosis factor-α and augmentation of interleukin-10

    Heme oxygenase-1 (HO-1) is an inducible defense gene which plays a significant role in inflammation. HO-1 protects cells and tissues through the mechanism of anti-oxidation, maintaining microcirculation and an...

    Fei-hu Zhang, Yu-han Sun, Kai-liang Fan, Xiao-bin Dong, Ning Han, Hao Zhao and Li Kong

    BMC Gastroenterology 2017 17:100

    Published on: 24 August 2017

  6. Research article

    Add-on neurological benefits of antiviral therapy in HCV patients with chronic kidney disease — a nationwide cohort study

    Hepatitis C virus (HCV)-infected patients with chronic kidney disease (CKD) have rarely been studied because they rarely accept interferon-based therapy (IBT) and have been difficult to follow up. We investiga...

    Ming-Shyan Lin, Tien-Hsing Chen, Wey-Yil Lin, Chi-Hung Liu, Yung-Yu Hsieh, Wen-Nan Chiu, Chih-Hsiang Chang, Mei-Yen Chen, Chang-Min Chung and Yu-Sheng Lin

    BMC Gastroenterology 2017 17:99

    Published on: 16 August 2017

  7. Research article

    Survival benefit of transarterial chemoembolization in patients with metastatic hepatocellular carcinoma: a single center experience

    As prognosis of patients with metastatic hepatocellular carcinoma (HCC) is mainly determined by intrahepatic HCC progression, local treatment with TACE may result in improved OS, although it is not recommended...

    Dominik Bettinger, Renan Spode, Nicolas Glaser, Nico Buettner, Tobias Boettler, Christoph Neumann-Haefelin, Thomas Baptist Brunner, Eleni Gkika, Lars Maruschke, Robert Thimme and Michael Schultheiss

    BMC Gastroenterology 2017 17:98

    Published on: 10 August 2017

  8. Research article

    Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study

    Glutathione plays crucial roles in the detoxification and antioxidant systems of cells and has been used to treat acute poisoning and chronic liver diseases by intravenous injection. This is a first study exam...

    Yasushi Honda, Takaomi Kessoku, Yoshio Sumida, Takashi Kobayashi, Takayuki Kato, Yuji Ogawa, Wataru Tomeno, Kento Imajo, Koji Fujita, Masato Yoneda, Koshi Kataoka, Masataka Taguri, Takeharu Yamanaka, Yuya Seko, Saiyu Tanaka, Satoru Saito…

    BMC Gastroenterology 2017 17:96

    Published on: 8 August 2017

  9. Research article

    Drug persistence and need for dose intensification to adalimumab therapy; the importance of therapeutic drug monitoring in inflammatory bowel diseases

    Therapeutic drug monitoring (TDM) aid therapeutic decision making in patients with inflammatory bowel disease (IBD) who lose response to anti-TNF therapy. Our aim was to evaluate the frequency and predictive f...

    Lorant Gonczi, Zsuzsanna Kurti, Mariann Rutka, Zsuzsanna Vegh, Klaudia Farkas, Barbara D. Lovasz, Petra A. Golovics, Krisztina B. Gecse, Balazs Szalay, Tamas Molnar and Peter L. Lakatos

    BMC Gastroenterology 2017 17:97

    Published on: 8 August 2017

  10. Research article

    Oral soft tissue disorders are associated with gastroesophageal reflux disease: retrospective study

    Dental erosion (DE), one of oral hard tissue diseases, is one of the extraoesophageal symptoms defined as the Montreal Definition and Classification of gastroesophageal reflux disease (GERD). However, no study...

    Masaaki Watanabe, Eiji Nakatani, Hiroo Yoshikawa, Takahiro Kanno, Yoshiki Nariai, Aya Yoshino, Michael Vieth, Yoshikazu Kinoshita and Joji Sekine

    BMC Gastroenterology 2017 17:92

    Published on: 7 August 2017

  11. Case report

    Life-threatening bleeding from gastric dieulafoy’s lesion in a pregnant woman with hellp syndrome: a case report and literature review

    Dieulafoy’s lesion (DL) is one of the rare causes of upper gastrointestional bleeding. This disease is characterized by small sub-mucosal arteriole that eroded the stomach mucosa and cause severe upper GI blee...

    Chen Si, Zhu Xiuli, Xie Li, Jia Yong, Zhou Ying and Zhang Kaiguang

    BMC Gastroenterology 2017 17:89

    Published on: 31 July 2017

  12. Research article

    The prevalence of gastric heterotopia of the proximal esophagus is underestimated, but preneoplasia is rare - correlation with Barrett’s esophagus

    The previously reported prevalence of gastric heterotopia in the cervical esophagus, also termed inlet patch (IP), varies substantially, ranging from 0.18 to 14%. Regarding cases with adenocarcinoma within IP,...

    Ulrich Peitz, Michael Vieth, Matthias Evert, Jovana Arand, Albert Roessner and Peter Malfertheiner

    BMC Gastroenterology 2017 17:87

    Published on: 12 July 2017

  13. Research article

    Risk of colorectal cancer among immigrants to Ontario, Canada

    The risk of colorectal cancer (CRC) varies around the world and between females and males. We aimed to compare the risk of CRC among immigrants to Ontario, Canada, to its general population.

    Lawrence Paszat, Rinku Sutradhar, Ying Liu, Nancy N. Baxter, Jill Tinmouth and Linda Rabeneck

    BMC Gastroenterology 2017 17:85

    Published on: 6 July 2017

  14. Research article

    Prokinetics for the treatment of functional dyspepsia: Bayesian network meta-analysis

    Controversies persist regarding the effect of prokinetics for the treatment of functional dyspepsia (FD). This study aimed to assess the comparative efficacy of prokinetic agents for the treatment of FD.

    Young Joo Yang, Chang Seok Bang, Gwang Ho Baik, Tae Young Park, Suk Pyo Shin, Ki Tae Suk and Dong Joon Kim

    BMC Gastroenterology 2017 17:83

    Published on: 26 June 2017

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