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  1. The rapid growth of Qatar in the last two decades has attracted a large influx of immigrant workers who mostly come from HEV-hyperendemic countries. Thus, we aim to investigate the prevalence of HEV among acut...

    Authors: Enas S. Al Absi, Duaa W. Al-Sadeq, Makiyeh Khalili, Nadin Younes, Nader Al-Dewik, Sara K. Abdelghany, Somaia S. Abouzid, Asma A. Al Thani, Hadi M. Yassine, Peter V. Coyle and Gheyath K. Nasrallah

    Citation: BMC Gastroenterology 2021 21:266

    Content type: Research article

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  2. Hepatocellular carcinoma (HCC), one of the most common malignant tumors worldwide, ranks as the fifth most common cancer and has been the second most frequent cause of cancer-related death. RNA binding protein...

    Authors: Zeng-Hong Wu, Hong-Ming Huang and Dong-Liang Yang

    Citation: BMC Gastroenterology 2021 21:265

    Content type: Research article

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  3. The aim of this study is to investigate the difference of serum pepsinogen (PG) baseline levels in different regions of China and its influencing factors.

    Authors: Yuling Tong, Hongguang Wang, Yi Zhao, Xueqiang He, Hongwei Xu, Hong Li, Ping Shuai, Lirong Gong, Hongbo Wu, Hongzhi Xu, Yinhu Luo, Dong Wang, Shizhu Liu and Zhenya Song

    Citation: BMC Gastroenterology 2021 21:264

    Content type: Research

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  4. Insulin is highly recommended for diabetes management in persons with liver cirrhosis. However, few studies have evaluated its long-term effects in these persons. We conducted this study to compare the risks o...

    Authors: Fu-Shun Yen, Jung-Nien Lai, James Cheng-Chung Wei, Lu-Ting Chiu, Chih-Cheng Hsu, Ming-Chih Hou and Chii-Min Hwu

    Citation: BMC Gastroenterology 2021 21:263

    Content type: Research

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  5. Hepatocellular carcinoma (HCC) can lead to liver failure which renders to liver transplant. miRNAs might be detected as biomarkers in subclinical stage of several hepatobiliary disorders like HCC. Therefore, i...

    Authors: Afsoon Afshari, Ramin Yaghobi, Mohammad Hossein Karimi and Javad Mowla

    Citation: BMC Gastroenterology 2021 21:262

    Content type: Research article

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  6. Pancreaticopleural fistula (PPF) is a rare complication of chronic pancreatitis (CP) that requires a high index of clinical suspicion in the patient who presents with a pleural effusion. Visualizing the fistul...

    Authors: Teera Kijmassuwan, Prapun Aanpreung, Varayu Prachayakul and Prakarn Tovichien

    Citation: BMC Gastroenterology 2021 21:261

    Content type: Case report

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  7. Targeted optical imaging offers a noninvasive and accurate method for the early detection of gastrointestinal tumors, especially for flat appearances. In our previous study, a sequence of SNFYMPL (SNF) was ide...

    Authors: Xiaoyu Kang, Meng Li, Lei liu, Shaopeng Liu, Hao Hu, Rui Zhang, Siming Ning, Zuhong Tian, Yanglin Pan, Xuegang Guo and Kaichun Wu

    Citation: BMC Gastroenterology 2021 21:260

    Content type: Research article

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  8. Real-world data regarding the impact of hepatic fibrosis on the effectiveness of sofosbuvir/velpatasvir (SOF/VEL) treatment is limited in the Asian population.

    Authors: Yu-Ting Huang, Yung-Yu Hsieh, Wei-Ming Chen, Shui-Yi Tung, Kuo-Liang Wei, Chen-Heng Shen, Kao-Chi Chang, Chung-Kuang Lu, Chih-Wei Yen, Sheng-Nan Lu, Chao-Hung Hung and Te-Sheng Chang

    Citation: BMC Gastroenterology 2021 21:259

    Content type: Research

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  9. Natural killer (NK) cells have been known to contribute to surveillance and control of hepatocellular carcinoma (HCC). However, the association of NK cell activity with stage and recurrence risk of HCC have no...

    Authors: Han Ah Lee, Hyun Gil Goh, Young-Sun Lee, Young Kul Jung, Ji Hoon Kim, Hyung Joon Yim, Min-Goo Lee, Hyunggin An, Yoon Tae Jeen, Jong Eun Yeon, Kwan Soo Byun and Yeon Seok Seo

    Citation: BMC Gastroenterology 2021 21:258

    Content type: Research

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  10. Cholangiocarcinoma is frequently observed in patients with congenital bile duct dilatation (CBDD). Most cholangiocarcinomas are adenocarcinomas. Other types, especially neuroendocrine carcinomas (NECs), are ra...

    Authors: Yoshitaka Kiya, Yuichi Nagakawa, Chie Takishita, Hiroaki Osakabe, Hitoe Nishino, Masanori Akashi, Hiroshi Yamaguchi, Toshitaka Nagao, Ryo Oono, Kenji Katsumata and Akihiko Tsuchida

    Citation: BMC Gastroenterology 2021 21:257

    Content type: Case report

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  12. The efficacy of endoscopic ultrasound (EUS) for determining the T category of gastric cancer is variable. The aim of this study was to evaluate the superiority of EUS by using the 6th edition American Joint Co...

    Authors: Chaoqun Han, Tao Xu, Qin Zhang, Jun Liu, Zhen Ding and Xiaohua Hou

    Citation: BMC Gastroenterology 2021 21:255

    Content type: Research article

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  13. Epstein–Barr virus (EBV)-associated NK/T-cell lymphoproliferative disorder (LPD) involving the gastrointestinal tract is rarely observed in individuals with normal immunity. The atypical clinical, colonoscopic...

    Authors: Si-Zhu Wang, Ying-Huan Dai, Jie Zhang, Fang-Gen Lu, La-Mei Yan and Shan Wu

    Citation: BMC Gastroenterology 2021 21:254

    Content type: Case report

    Published on:

  14. Hemostasis profile is often complicated in liver cirrhosis. Thromboelastography is a global viscoelastic test recommended by the current practice guideline and consensus. This cross-sectional study aimed to ev...

    Authors: Yanglan He, Shanshan Yuan, Xiaozhong Guo, Fangfang Yi, Xiangbo Xu, Yang An, Shixue Xu, Walter Ageno and Xingshun Qi

    Citation: BMC Gastroenterology 2021 21:253

    Content type: Research

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  15. The aim of this study was to analyze prognostic indicators of in-hospital mortality among patients listed for urgent liver transplantation (LT) for non-acetaminophen (APAP)-induced acute liver failure (ALF).

    Authors: Estela Regina Ramos Figueira, Joel Avancini Rocha-Filho, Cinthia Lanchotte, Lucas Souto Nacif, Luciana Bertocco de Paiva Haddad, Adriana Rochetto Assalin, Yumi Ricucci Shinkado, Agustin Moscoso Vintimilla, Flavio Henrique Ferreira Galvao and Luiz Augusto Carneiro D’Albuquerque

    Citation: BMC Gastroenterology 2021 21:252

    Content type: Research

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  16. The Micro Hand S robot is a new surgical tool that has been applied to total mesorectal excision (TME) surgery for rectal cancer in our center. In this study, we compared the operative outcomes, functional out...

    Authors: Yanlei Wang, Guohui Wang, Zheng Li, Hao Ling, Bo Yi and Shaihong Zhu

    Citation: BMC Gastroenterology 2021 21:251

    Content type: Research

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  17. Few studies have reported whether a biopsy in emergency gastroscopy (EG) increased the risk of rebleeding in patients with Forrest I acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) combined with su...

    Authors: Quchuan Zhao and Tianyu Chi

    Citation: BMC Gastroenterology 2021 21:250

    Content type: Research

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  18. The right posterior segment (RPS) graft was introduced to overcome graft size discrepancy in living donor liver transplantation (LDLT). However, it was very rarely used in pediatric patients. Here we presented...

    Authors: Xiaoye Qu, Ping Wan, Mingxuan Feng, Bijun Qiu, Yi Luo, Tao Zhou, Jianjun Zhu, Dong Zhao, Guangxiang Gu, Jianjun Zhang and Qiang Xia

    Citation: BMC Gastroenterology 2021 21:249

    Content type: Research

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  20. Undifferentiated carcinoma with osteoclast-like giant cells (UCOGCs) is a rare and aggressive non endocrine pancreatic carcinoma characterized by the presence of osteoclastic giant cells mixed with mononuclear...

    Authors: Elisabetta Cavalcanti, Nicolo’ Schena, Grazia Serino, Giulio Lantone and Raffaele Armentano

    Citation: BMC Gastroenterology 2021 21:247

    Content type: Case report

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  22. Several trend analyses on liver transplantation (LT) indications have been published in the U.S. and in other countries, but there are limited data on LT indication trends in Saudi Arabia (SA), especially sinc...

    Authors: Saleh A. Alqahtani, Dieter C. Broering, Saad A. Alghamdi, Khalid I. Bzeizi, Noara Alhusseini, Saleh I. Alabbad, Ali Albenmousa, Nasreen Alfaris, Faisal Abaalkhail and Waleed K. Al-hamoudi

    Citation: BMC Gastroenterology 2021 21:245

    Content type: Research

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  23. Zanubrutinib is a Bruton’s tyrosine kinase inhibitor that has been recently licensed in refractory mantle cell lymphoma and under assessment in phase 3 clinical trials for other B cell malignancies. To date, t...

    Authors: Edmond Atallah, Pramudi Wijayasiri, Nicole Cianci, Khorrum Abdullah, Abhik Mukherjee and Guruprasad P. Aithal

    Citation: BMC Gastroenterology 2021 21:244

    Content type: Case report

    Published on:

  24. Symptoms associated with acute pancreatitis can be debilitating, and treatment remains a challenge. This study aimed to investigate the efficacy of selectively inhibiting the soluble form of TNF (solTNF) using...

    Authors: Rajasa Randhi, Melissa Damon and Kirsty J. Dixon

    Citation: BMC Gastroenterology 2021 21:243

    Content type: Research

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  25. Three-dimensional (3D) technology has been used in many fields, including flexible endoscopy. We evaluated the usefulness of 3D visualization for endoscopically diagnosing superficial gastric neoplasia.

    Authors: Kazutoshi Higuchi, Mitsuru Kaise, Hiroto Noda, Kumiko Kirita, Eriko Koizumi, Takamitsu Umeda, Teppei Akimoto, Jun Omori, Naohiko Akimoto, Osamu Goto, Atsushi Tatsuguchi and Katsuhiko Iwakiri

    Citation: BMC Gastroenterology 2021 21:242

    Content type: Research

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  26. A chronic expanding hematoma (CEH) enlarges as a result of slight bleeding over several months, and the tissue shows a mixture of blood breakdown products, granulation tissue with capillary ingrowth, and infla...

    Authors: Yasuyuki Ono, Shuji Kariya, Miyuki Nakatani, Yutaka Ueno, Takuji Maruyama, Atsushi Komemushi, Masaki Kaibori, Masatoshi Ikeda and Noboru Tanigawa

    Citation: BMC Gastroenterology 2021 21:241

    Content type: Case report

    Published on:

  28. The waist-to-height ratio (WHtR) has been recognised as a powerful indicator to evaluate non-alcoholic fatty liver disease (NAFLD) in recent years, but few related studies are available. Thus, clarifying the a...

    Authors: Guotai Sheng, Qiyang Xie, Rongsheng Wang, Chong Hu, Mingchun Zhong and Yang Zou

    Citation: BMC Gastroenterology 2021 21:239

    Content type: Research

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  29. Neuroendocrine tumors (NETs), as a rare and heterogeneous category of solid tumors, feature various morphologies and behaviors. In recent years, the incidence of NETs has continued to increase. Endoscopic muco...

    Authors: Gholam Reza Sivandzadeh, Fardad Ejtehadi, Shima Shoaee, Ladan Aminlari, Ramin Niknam, Ali Reza Taghavi, Bita Geramizadeh, Ahmad Hormati, Ali Reza Safarpour and Kamran Bagheri Lankarani

    Citation: BMC Gastroenterology 2021 21:238

    Content type: Research

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  30. We conducted a randomized controlled trial to investigate the effects of consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 in women healthcare workers. In a previous study ...

    Authors: Tetsu Kinoshita, Koutatsu Maruyama, Keiko Suyama, Mariko Nishijima, Kimiko Akamatsu, Akiko Jogamoto, Kikumi Katakami and Isao Saito

    Citation: BMC Gastroenterology 2021 21:237

    Content type: Research article

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  31. Vonoprazan is more potent and longer acting than traditional proton pump inhibitor. Although vonoprazan is expected to be superior to proton pump inhibitor, its efficacy in the treatment of gastric ulcers foll...

    Authors: Daisuke Kawai, Ryuta Takenaka, Mikako Ishiguro, Shotaro Okanoue, Tatsuhiro Gotoda, Yoshiyasu Kono, Koji Takemoto, Hirofumi Tsugeno and Shigeatsu Fujiki

    Citation: BMC Gastroenterology 2021 21:236

    Content type: Research article

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  32. Irritable bowel syndrome (IBS) is characterised by gastrointestinal (GI) and psychological symptoms (e.g., depression, anxiety, and somatization). Depression and anxiety, but not somatization, have already bee...

    Authors: Laura Prospero, Giuseppe Riezzo, Michele Linsalata, Antonella Orlando, Benedetta D’Attoma, Marta Di Masi, Manuela Martulli and Francesco Russo

    Citation: BMC Gastroenterology 2021 21:235

    Content type: Research

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  33. The Cryoballoon focal ablation system (CbFAS) for dysplastic Barrett’s esophagus is simple, time-saving and has high therapeutic efficacy. This study aimed to evaluate the technical feasibility and tissue dama...

    Authors: Hironori Sunakawa, Yusuke Yoda, Nobuyoshi Takeshita, Hiro Hasegawa, Kenji Takashima, Tomohiro Kadota, Takeo Fujita, Tetsuo Akimoto, Satoshi Fujii and Tomonori Yano

    Citation: BMC Gastroenterology 2021 21:234

    Content type: Research

    Published on:

  34. As a nutritional index, preoperative serum prealbumin highly correlates with surgical complications. However, the correlation between preoperative prealbumin and postoperative complications remains unclear in ...

    Authors: Yuancheng Li, Xingchao Liu, Yan Jiang, Kun Wan, Wei Liu, Yanjiao Ou, Jie Bai, Yuemei You, Feng Hu, Zeliang Xu, Ping Bie, Chengcheng Zhang and Leida Zhang

    Citation: BMC Gastroenterology 2021 21:233

    Content type: Research

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  35. High quality bowel preparation prior to colonoscopy can be difficult to achieve in the inpatient setting. Hospitalized patients are at risk for extended hospital stays and low diagnostic yield due to inadequat...

    Authors: Helmut Neumann, Melissa Latorre, Tim Zimmerman, Gabriel Lang, Jason Samarasena, Seth Gross, Bhaumik Brahmbhatt, Haleh Pazwash and Vladimir Kushnir

    Citation: BMC Gastroenterology 2021 21:232

    Content type: Research

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  36. The clinical outcomes of drug-eluting beads transarterial chemoembolization (DEB-TACE) with doxorubicin-loaded CalliSpheres® beads for patients with unresectable or recurrent esophageal carcinoma have not been...

    Authors: Yonghua Bi, Xiaonan Shi, Jianzhuang Ren, Mengfei Yi, Xinwei Han and Min Song

    Citation: BMC Gastroenterology 2021 21:231

    Content type: Research article

    Published on:

  37. The effect of time delay from diagnosis to surgery on the prognosis of elderly patients with liver cancer is not well known. We investigated the effect of surgical timing on the prognosis of elderly hepatocell...

    Authors: Yongfei He, Tianyi Liang, Shutian Mo, Zijun Chen, Shuqi Zhao, Xin Zhou, Liping Yan, Xiangkun Wang, Hao Su, Guangzhi Zhu, Chuangye Han and Tao Peng

    Citation: BMC Gastroenterology 2021 21:230

    Content type: Research article

    Published on:

  38. Wilson’s disease (WD) is a rare autosomal recessive disease associated with defective biliary excretion of copper. The simultaneous occurrence of WD and systemic lupus erythematosus (SLE) has seldom been repor...

    Authors: Lishan Xu, Bin Liu, Zhaoyang Liu, Ning Tang, Chunhui She, Jing Wang, Bo Zang and Yifei Yang

    Citation: BMC Gastroenterology 2021 21:229

    Content type: Case report

    Published on:

  40. Immune checkpoint inhibitors (ICPIs) have changed the way advanced malignancies are currently confronted, improving cancer patients’ outcomes but also generating distinct immune-related (ir) adverse events. IC...

    Authors: Stratigoula Sakellariou, Dionysia N. Zouki, Dimitrios C. Ziogas, Despoina Pouloudi, Helen Gogas and Ioanna Delladetsima

    Citation: BMC Gastroenterology 2021 21:227

    Content type: Case report

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  41. Percutaneous transhepatic gallbladder drainage (PTGBD) is recommended for acute cholecystitis patients at high risk for surgical treatment. However, there is no evidence about the best timing of surgery after ...

    Authors: Koichi Kimura, Eisuke Adachi, Sachie Omori, Ayako Toyohara, Takahiro Higashi, Kippei Ohgaki, Shuhei Ito, Shin-ichiro Maehara, Toshihiko Nakamura, Yoichi Ikeda and Yoshihiko Maehara

    Citation: BMC Gastroenterology 2021 21:226

    Content type: Research

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  43. Endoscopic papillectomy of duodenal papillary tumors (PT) is indicated for adenomas or well-differentiated adenocarcinomas that do not involve the sphincter of Oddi. However, there is currently no reliable pre...

    Authors: Hiroyuki Tanaka, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Tadashi Iida, Eri Ishikawa, Kazuhiro Furukawa, Masanao Nakamura, Takashi Honda, Yoshie Shimoyama, Ryoji Miyahara, Naoto Kawabe, Teiji Kuzuya, Senju Hashimoto, Masatoshi Ishigami, Yoshiki Hirooka…

    Citation: BMC Gastroenterology 2021 21:224

    Content type: Research

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  44. In this study, to clarify the evolving background of people with non-alcoholic fatty liver disease (NAFLD), we compared the current prevalence of NAFLD with that of 2 decades ago.

    Authors: Takuro Okamura, Yoshitaka Hashimoto, Masahide Hamaguchi, Akihiro Obora, Takao Kojima and Michiaki Fukui

    Citation: BMC Gastroenterology 2021 21:223

    Content type: Research

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  45. Jackhammer esophagus is a rare esophageal motility disorder that can result in dysphagia, chest pain, and gastro-esophageal reflux symptoms. High-resolution manometry is the gold standard for diagnosis, while ...

    Authors: Apichet Sirinawasatien and Pallop Sakulthongthawin

    Citation: BMC Gastroenterology 2021 21:222

    Content type: Case report

    Published on:

  46. Non-alcohol fatty liver disease (NAFLD) is the most common liver disease and an unhealthy lifestyle can lead to an increased risk of NAFLD. The present study aims to evaluate the association of meat consumptio...

    Authors: Hewei Peng, Xiaoxu Xie, Xinting Pan, Jing Zheng, Yidan Zeng, Xiaoling Cai, Zhijian Hu and Xian-E Peng

    Citation: BMC Gastroenterology 2021 21:221

    Content type: Research article

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  47. The benefits of surgical resection (SR) for various Barcelona Clinic Liver Cancer (BCLC) stages of hepatocellular carcinoma (HCC) remain unclear. We investigated the risk factors of overall survival (OS) and s...

    Authors: Yaw-Sen Chen, Pei-Min Hsieh, Hung-Yu Lin, Chao-Ming Hung, Gin-Ho Lo, Yao-Chun Hsu, I.-Cheng Lu, Chih-Yuan Lee, Tsung-Chin Wu, Jen-Hao Yeh, Pojen Hsiao, Yu-Chan Li, Ya-Chin Wang, Kun-Chou Hsieh and Chih-Wen Lin

    Citation: BMC Gastroenterology 2021 21:220

    Content type: Research article

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  48. Schistosoma mansoni related hepatic fibrosis is usually associated with hemodynamic alteration with increased mortality due to bleeding varices. The diagnosis of varices before bleeding imposes a big challenge in...

    Authors: Daniel W. Gunda, Elizabeth F. Mtui, Paulina M. Manyiri, David C. Majinge, Semvua B. Kilonzo, Humphrey D. Mazigo and Benson R. Kidenya

    Citation: BMC Gastroenterology 2021 21:219

    Content type: Research article

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  50. This retrospective analysis was undertaken to evaluate the efficiency of SIRT with Y-90 microspheres and determined prognostic factors affecting patients with unresectable HCC.

    Authors: Nguyen Van Thai, Nguyen Tien Thinh, Thai Doan Ky, Mai Hong Bang, Dinh Truong Giang, Le Ngoc Ha, Mai Hong Son, Dao Duc Tien and Hyun Woong Lee

    Citation: BMC Gastroenterology 2021 21:216

    Content type: Research

    Published on:

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