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  1. The impact of liver cirrhosis on the outcomes of admission to intensive care unit (ICU) is not completely understood. Our purpose is to identify risk factors for mortality in ICU patients with liver cirrhosis.

    Authors: Yu-Feng Huang, Chao-Shun Lin, Yih-Giun Cherng, Chun-Chieh Yeh, Ray-Jade Chen, Ta-Liang Chen and Chien-Chang Liao

    Citation: BMC Gastroenterology 2020 20:15

    Content type: Research article

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  2. To investigate the merit of T1rho relaxation for the evaluation of liver fibrosis, inflammatory activity, and liver injury monitoring in a carbon tetrachloride (CCl4)-induced rat model.

    Authors: Shuangshuang Xie, Hanxiong Qi, Qing Li, Kun Zhang, Longjiang Zhang, Yue Cheng and Wen Shen

    Citation: BMC Gastroenterology 2020 20:14

    Content type: Research article

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  3. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has high accuracy and a low complication rate; therefore, it has been widely used as a useful tool for diagnosis of and to determine treatment stra...

    Authors: Nami Sato, Shigetsugu Takano, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Takashi Mishima, Eri Nakadai, Rintaro Mikata, Naoya Kato and Masayuki Ohtsuka

    Citation: BMC Gastroenterology 2020 20:13

    Content type: Case report

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  4. Gankyrin (GK) is an oncoprotein which regulates inflammatory responses and its inhibition is considered as a possible anti-inflammatory therapy for inflammatory bowel disease (IBD).

    Authors: Toshiharu Sakurai, Hiroki Nishiyama, Tomoyuki Nagai, Susumu Goto, Hiroyuki Ogata and Masatoshi Kudo

    Citation: BMC Gastroenterology 2020 20:12

    Content type: Research article

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  5. Previous studies have indicated that disease activity, psychological symptoms and social support were associated with health-related quality of life (HRQoL) in patients with inflammatory bowel diseases(IBD). H...

    Authors: Hanlin Fu, Atipatsa Chiwanda Kaminga, Yan Peng, Tiejian Feng, Tingting Wang, Xiaobing Wu and Tubao Yang

    Citation: BMC Gastroenterology 2020 20:11

    Content type: Research article

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  6. ALT value is often used to reflect the hepatic inflammation and injury in NAFLD patients, but many studies proved that ALT values were normal in many NAFLD patients. The aim of this study was to identify the s...

    Authors: Xuefeng Ma, Shousheng Liu, Jie Zhang, Mengzhen Dong, Yifen Wang, Mengke Wang and Yongning Xin

    Citation: BMC Gastroenterology 2020 20:10

    Content type: Research article

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  7. Epstein–Barr virus-positive mucocutaneous ulcer (EBV-MCU) is a new category of mature B-cell neoplasms. Ulcers occur in the oropharyngeal mucosa, skin, and gastrointestinal tract. The onset of EBV-MCU is sugge...

    Authors: Nozomi Morita, Chiaki Okuse, Keigo Suetani, Hiroyasu Nakano, Tetsuya Hiraishi, Shinya Ishigooka, Shuzo Mori, Tsukasa Shimamura, Takeshi Asakura, Junki Koike, Fumio Itoh and Michihiro Suzuki

    Citation: BMC Gastroenterology 2020 20:9

    Content type: Case report

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  8. Interleukin-10 (IL10) signalling pathway deficiency results in severe very early onset inflammatory bowel disease (VEOIBD), and enterostomy is often inevitable. However, studies in these surgical populations a...

    Authors: Zifei Tang, Zhiheng Huang, Weili Yan, Yi Zhang, Peng Shi, Kuiran Dong, Ying Gong, Min Ji, Yuhuan Wang, Zhuowe Yu and Ying Huang

    Citation: BMC Gastroenterology 2020 20:8

    Content type: Research article

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  9. The anti-immunological rejection therapy for small-for-size syndrome (SFSS) after live donor liver transplantation (LDLT) play a central role in keeping graft survival. The hepatocyte number and grafts functio...

    Authors: Yanhu Feng, Zhijian Han, Zedong Feng, Bofang Wang, Huijuan Cheng, Luxi Yang, Yangbing Li, Baohong Gu, Xuemei Li, Yahao Li, Yumin Li, Chen Wang and Hao Chen

    Citation: BMC Gastroenterology 2020 20:7

    Content type: Research article

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  10. Aspirin has been found to lower the occurrence rates of some cancers through the inhibition of the cyclooxygenase enzyme. For example, there is a well-known association between aspirin use and the occurrence o...

    Authors: Yen-Hsiang Liao, Ren-Jun Hsu, Tzu-Hwei Wang, Chen-Ta Wu, Sheng-Yao Huang, Chung-Y. Hsu, Yuan-Chih Su, Wen-Lin Hsu and Dai-Wei Liu

    Citation: BMC Gastroenterology 2020 20:6

    Content type: Research article

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  11. The duodenum is a common site for diverticulum formation. Most of the duodenal diverticula are asymptomatic, incidental findings. Perforation is a rare but potentially lethal complication of duodenal diverticu...

    Authors: Moysis Moysidis, Daniel Paramythiotis, Anestis Karakatsanis, Evropi Amanatidou, Elisavet Psoma, Xanthippi Mavropoulou and Antonios Michalopoulos

    Citation: BMC Gastroenterology 2020 20:5

    Content type: Case report

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  12. Recent evidence cautions against the use of non-selective beta-blockers (NSBB) in patients with refractory ascites or spontaneous bacterial peritonitis while other data suggests a survival benefit in patients ...

    Authors: Taiwo Ngwa, Eric Orman, Eduardo Vilar Gomez, Raj Vuppalanchi, Chandrashekhar Kubal, Naga Chalasani and Marwan Ghabril

    Citation: BMC Gastroenterology 2020 20:4

    Content type: Research article

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  13. Little is known about the natural history of serrated polyps (SPs), partly due to the lack of large-scale epidemiologic data. In this study, we examined the validity of SP identification according to SNOMED (S...

    Authors: Soran R. Bozorg, Mingyang Song, Louise Emilsson and Jonas F. Ludvigsson

    Citation: BMC Gastroenterology 2019 20:3

    Content type: Research article

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  14. The aim of this study was to investigate the efficacy and safety of the novel complex drug, consisting of released-active form of antibodies to S-100 protein, tumor necrosis factor-α and histamine, (Kolofort) ...

    Authors: Vladimir T. Ivashkin, Elena A. Poluektova, Alexey B. Glazunov, Mikhail A. Putilovskiy and Oleg I. Epstein

    Citation: BMC Gastroenterology 2019 20:2

    Content type: Research article

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  15. The multifactorial mechanisms driving negative health outcomes among risky drinkers with HIV may include immunosenescence. Immunosenescence, aging of the immune system, may be accentuated in HIV and leads to p...

    Authors: Kaku So-Armah, Matthew Freiberg, Debbie Cheng, Joseph K. Lim, Natalia Gnatienko, Gregory Patts, Margaret Doyle, Daniel Fuster, Dmitry Lioznov, Evgeny Krupitsky and Jeffrey Samet

    Citation: BMC Gastroenterology 2019 20:1

    Content type: Research article

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  16. Double-balloon enteroscopy enables performing numerous small bowel biopsies for pathologic analysis. However, most histopathological characteristics of Crohn’s disease are non-specific characteristics. We aime...

    Authors: Yun Cui, Shi-yuan Lu, Jie Xu, Yan-shen Peng, Qi Miao, Xiao-qing Wang, Xiao-yu Chen and Zhi-hua Ran

    Citation: BMC Gastroenterology 2019 19:232

    Content type: Research article

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  17. Statin has been more and more widely used in chronic liver disease, however, existed studies have attained contradictory results. According to the present study, we aimed to test the efficacy and safety of sta...

    Authors: Yue Gu, Xueqin Yang, Hang Liang and Deli Li

    Citation: BMC Gastroenterology 2019 19:231

    Content type: Research article

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  18. Hepatocellular carcinoma (HCC) is a common human malignant cancer due to a high metastatic capacity and the recurrence rate is also high. This study is aim to investigate the role of musashi1 as a potential bi...

    Authors: Qiuhua Liu, Cuijie Zhou and Bo Zhang

    Citation: BMC Gastroenterology 2019 19:230

    Content type: Research article

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  19. A large-scale Japanese study showed that low skeletal muscle index (SMI) and intramuscular fat (IMF) deposition are associated with hepatocellular carcinoma (HCC) survival. Here, we evaluated the effects of SM...

    Authors: Yan Mardian, Yoshihiko Yano, Neneng Ratnasari, Lina Choridah, Widya Wasityastuti, Nurhuda Hendra Setyawan and Yoshitake Hayashi

    Citation: BMC Gastroenterology 2019 19:229

    Content type: Research article

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  20. Compounds in clinical development for nonalcoholic steatohepatitis (NASH) improve liver histopathology in diet-induced obese mouse models of biopsy-confirmed NASH. Since the biopsy section used for histopathol...

    Authors: Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Christina Christoffersen, Michael Feigh, Niels Vrang, Jonathan David Roth, Mary Erickson, Luciano Adorini and Jacob Jelsing

    Citation: BMC Gastroenterology 2019 19:228

    Content type: Research article

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  21. Gastrointestinal stromal tumors (GISTs) at the esophagogastric junction are rare and its treatment is complicated and challenging. Endoscopic resection has advantages with less complications compared to open a...

    Authors: Feng Xue, Wei Wang, Ning Shi, Xing-Bin Ma and Cheng-Xia Liu

    Citation: BMC Gastroenterology 2019 19:227

    Content type: Case report

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  22. The Asia-Pacific Colorectal Screening (APCS) score is effective to screen high-risk groups of advanced colorectal neoplasia (ACN) patients but needs revising and can be combined with the fecal immunochemical t...

    Authors: Xu-xia He, Si-yi Yuan, Wen-bin Li, Hong Yang, Wen Ji, Zhi-qiang Wang, Jian-yu Hao, Chuan Chen, Wei-qing Chen, Ying-xin Gao, Ling-bo Li, Kai-liang Cheng, Jia-ming Qian, Li Wang and Jing-nan Li

    Citation: BMC Gastroenterology 2019 19:226

    Content type: Research article

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  23. Conventional endoscopic treatments can’t control bleeding in as many as 20% of patients with non-variceal gastrointestinal (GI) bleeding. Recent studies have shown that over-the-scope-clip (OTSC) system allowe...

    Authors: Chunyu Zhong, Shali Tan, Yutang Ren, Muhan Lü, Yan Peng, Xiangsheng Fu and Xiaowei Tang

    Citation: BMC Gastroenterology 2019 19:225

    Content type: Research article

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  24. Various types of medical glues/adhesives/topical coagulants’ (referred to as MG hereinafter) have widespread application as surgical adhesives, and have been shown to be safe and effective for a broad range of...

    Authors: Wei Li, Mingming Xiao, Yujia Chen, Jiaxing Yang, Donghui Sun, Jian Suo and Daguang Wang

    Citation: BMC Gastroenterology 2019 19:224

    Content type: Case report

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  25. Malnutrition is a common problem among children with chronic liver diseases (CLD). We aimed to assess the nutritional status of children with CLD and to correlate the anthropometric indices with the severity o...

    Authors: Nehal El Koofy, Eman Mohamed Ibraheim Moawad, Mona Fahmy, Mona Anwar Mohamed, Hany Fathy Ahmed Mohamed, Ehab Mohamed Eid, Moushira Errfan Zaki and Rokaya Mohamed El-Sayed

    Citation: BMC Gastroenterology 2019 19:223

    Content type: Research article

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  26. Endoscopic nasobiliary drainage (ENBD) is widely used for biliary decompression in patients with biliary disease. However, it is difficult to reposition a nasobiliary catheter from the mouth to nostril. We dev...

    Authors: Seong Ji Choi, Jae Min Lee, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim and Chi Hyuk Oh

    Citation: BMC Gastroenterology 2019 19:222

    Content type: Research article

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  27. Nerve growth factor (NGF) and enteric glial cells (EGCs) are associated with visceral hypersensitivity and gastrointestinal motility disorder, which may represent the pathogenesis of functional dyspepsia (FD)....

    Authors: Haitao Shi, Shanshan Zhu, Bin Qin, Lianli Wang, Juan Yang, Guolong Lu and Fei Dai

    Citation: BMC Gastroenterology 2019 19:221

    Content type: Research article

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  28. Endoscopic ultrasound is useful for obtaining high-resolution images of pancreaticobiliary diseases, but is not readily available for physical checkups. In this study, we evaluated the safety and efficacy of s...

    Authors: Daisuke Uchida, Hironari Kato, Kazuyuki Matsumoto, Yuki Ishihara, Akihiro Matsumi, Yosuke Saragai, Saimon Takada, Shuntaro Yabe, Shinichiro Muro, Takeshi Tomoda, Shigeru Horiguchi and Hiroyuki Okada

    Citation: BMC Gastroenterology 2019 19:220

    Content type: Research article

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  29. Alternate-day fasting (ADF) is a novel diet therapy that may achieve reduction in body weight and improvement of dyslipidaemia, but the impact of this diet on patients with non-alcoholic fatty liver disease (N...

    Authors: Hua Cai, Yue-Lan Qin, Ze-Ya Shi, Jin-Hui Chen, Min-Jie Zeng, Wei Zhou, Ru-Qun Chen and Zhi-Yuan Chen

    Citation: BMC Gastroenterology 2019 19:219

    Content type: Research article

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  30. Upper gastrointestinal endoscopic examination is a relatively safe procedure; however, all endoscopic procedures are invasive and are associated with a risk of iatrogenic perforation. To evaluate clinical outc...

    Authors: Dae Hwan Kang, Dae Gon Ryu, Cheol Woong Choi, Hyung Wook Kim, Su Bum Park, Su Jin Kim and Hyeong Seok Nam

    Citation: BMC Gastroenterology 2019 19:218

    Content type: Research article

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  31. Portal vein thrombosis (PVT) is a common complication of cirrhosis. However, in patients with PVT and cirrhosis, there is no clear evidence supporting effective treatment modalities. In this study, we examined...

    Authors: Takehiro Hayashi, Hajime Takatori, Rika Horii, Kouki Nio, Takeshi Terashima, Noriho Iida, Masaaki Kitahara, Tetsuro Shimakami, Kuniaki Arai, Kazuya Kitamura, Kazunori Kawaguchi, Taro Yamashita, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda…

    Citation: BMC Gastroenterology 2019 19:217

    Content type: Research article

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  32. Capsule endoscopy (CE) is the preferred diagnostic test of choice in the investigation of obscure gastrointestinal bleeding (OGIB). Although, a conservative strategy is recommended in the short-term, for cases...

    Authors: Panu Wetwittayakhlang, Jirapat Wonglhow, Nisa Netinatsunton, Naichaya Chamroonkul and Teerha Piratvisuth

    Citation: BMC Gastroenterology 2019 19:216

    Content type: Research article

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  34. Endoscopic treatment of post-cholecystectomy biliary strictures (PCBS) with multiple plastic biliary stents placed sequentially is a minimally invasive alternative to surgery but requires multiple intervention...

    Authors: Andrea Tringali, D. Nageshwar Reddy, Thierry Ponchon, Horst Neuhaus, Ferrán González-Huix Lladó, Claudio Navarrete, Marco J. Bruno, Paul P. Kortan, Sundeep Lakhtakia, Joyce Peetermans, Matthew Rousseau, David Carr-Locke, Jacques Devière and Guido Costamagna

    Citation: BMC Gastroenterology 2019 19:214

    Content type: Research article

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  35. Many patients present in primary care with lower bowel symptoms, but significant bowel disease (SBD), comprising colorectal cancer (CRC), advanced adenoma (AA), or inflammatory bowel disease (IBD), is uncommon...

    Authors: Jayne Digby, Judith A. Strachan, Craig Mowat, Robert J. C. Steele and Callum G. Fraser

    Citation: BMC Gastroenterology 2019 19:213

    Content type: Research article

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  36. Upper gastrointestinal bleeding (UGIB) is a common emergency department (ED) presentation with high morbidity and mortality. There is a paucity of data on the profile and outcome of patients who present with U...

    Authors: Shaffin S. Rajan, Hendry R. Sawe, Asha J. Iyullu, Dereck A. Kaale, Nancy A. Olambo, Juma A. Mfinanga and Ellen J. Weber

    Citation: BMC Gastroenterology 2019 19:212

    Content type: Research article

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  37. The clinical value of the controlling nutritional status (CONUT) score in hepatocellular carcinoma (HCC) has increased. The aim of this meta-analysis was to systematically review the association between the CO...

    Authors: Kosei Takagi, Piotr Domagala, Wojciech G. Polak, Stefan Buettner and Jan N. M. Ijzermans

    Citation: BMC Gastroenterology 2019 19:211

    Content type: Research article

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  38. Fecal calprotectin (FCP), magnetic resonance enterography (MRE), and colonoscopy are complementary biometric tests that are used to assess patients with Crohn’s Disease (CD). While prior studies have evaluated...

    Authors: Alexander S. Somwaru, Vikesh Khanijow and Venkat S. Katabathina

    Citation: BMC Gastroenterology 2019 19:210

    Content type: Research article

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  39. Clear evidence on the benefit-harm balance and cost effectiveness of population-based screening for colorectal cancer (CRC) is missing. We aim to systematically evaluate the long-term effectiveness, harms and ...

    Authors: Beate Jahn, Gaby Sroczynski, Marvin Bundo, Nikolai Mühlberger, Sibylle Puntscher, Jovan Todorovic, Ursula Rochau, Willi Oberaigner, Hendrik Koffijberg, Timo Fischer, Irmgard Schiller-Fruehwirth, Dietmar Öfner, Friedrich Renner, Michael Jonas, Monika Hackl, Monika Ferlitsch…

    Citation: BMC Gastroenterology 2019 19:209

    Content type: Research article

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  42. Heparin bridging therapy (HBT) is indeed related to a high frequency of bleeding after endoscopic mucosal resection (EMR). In this study, our aim was to investigate clinical impact of management of oral antico...

    Authors: Shoko Ono, Marin Ishikawa, Kana Matsuda, Momoko Tsuda, Keiko Yamamoto, Yuichi Shimizu and Naoya Sakamoto

    Citation: BMC Gastroenterology 2019 19:206

    Content type: Research article

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  43. To determine the indications for adjuvant chemotherapy (AC) in patients with stage IIa gastric cancer (T3N0M0 and T1N2M0) according to the 7th American Joint Committee on Cancer (AJCC).

    Authors: Ze-Ning Huang, Jacopo Desiderio, Qi-Yue Chen, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ju-Li Lin, Hua-Long Zheng and Chang-Ming Huang

    Citation: BMC Gastroenterology 2019 19:205

    Content type: Research article

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  44. Irritable bowel syndrome (IBS) is prevalent in patients with morbid obesity. After Roux-en-Y gastric bypass (RYGB) chronic abdominal pain is common, however the etiology is largely unknown. We aimed to study t...

    Authors: Ingvild Kristine Blom-Høgestøl, Martin Aasbrenn, Monica Chahal-Kummen, Cathrine Brunborg, Inger Eribe, Jon Kristinsson, Per G. Farup and Tom Mala

    Citation: BMC Gastroenterology 2019 19:204

    Content type: Research article

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  45. Bleeding esophageal varices is a deadly complication of liver cirrhosis. Guidelines recommend an early diagnosis of esophageal varices before incident bleeding by screening all patients diagnosed with liver ci...

    Authors: Daniel W. Gunda, Semvua B. Kilonzo, Zakhia Mamballah, Paulina M. Manyiri, David C. Majinge, Hyasinta Jaka, Benson R. Kidenya and Humphrey D. Mazigo

    Citation: BMC Gastroenterology 2019 19:203

    Content type: Research article

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  48. Drug induced liver injury (DILI) is an important cause of acute liver injury and accounts for approximately 10% of all cases of acute hepatitis. Both prescription and natural health products (NHPs) have been i...

    Authors: Tyler Pitre, Jasmine Mah, Jaclyn Vertes, Rosario Rebello and Julie Zhu

    Citation: BMC Gastroenterology 2019 19:199

    Content type: Case report

    Published on:

  49. This case seeks to highlight to endoscopists a rare benign disorder that may be encountered during endoscopy. Clinicians may be tempted to biopsy, which could lead to a catastrophic gastrointestinal haemorrhage.

    Authors: Kushala W. M. Abeysekera, Daniel S. Pearl, Paul Burn and Andrew Lowe

    Citation: BMC Gastroenterology 2019 19:198

    Content type: Case report

    Published on:

  50. Pancreatic cavernous hemangioma is an extremely rare benign tumor that is difficult to diagnose on an imaging examination, and its histopathological examination has rarely been reported.

    Authors: Tao Lianyuan, Wang Yafeng, Yu Haibo, Dong Yadong, Ma Jiahao, Lu Yuanxiang and Li Deyu

    Citation: BMC Gastroenterology 2019 19:197

    Content type: Case report

    Published on:

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