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  1. Percutaneous Endoscopic Gastrostomy (PEG) feeding tubes are frequently placed in patients to provide enteral nutrition. We report a case of a complete rupture of a PEG tube intra-abdominally with associated pe...

    Authors: Maan Al Halabi, Wakim Wakim, Hicham Moukaddam and Ahmad Husari

    Citation: BMC Gastroenterology 2020 20:82

    Content type: Case report

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  2. Vascular invasion is an important criterion for resectability and deciding the therapeutic strategy for pancreatic ductal adenocarcinoma (PDAC), but imaging diagnosis is currently difficult. Endoscopic ultraso...

    Authors: Kenta Yamada, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Hiroyuki Tanaka, Masanao Nakamura, Ryoji Miyahara, Masatoshi Ishigami, Yoshiki Hirooka and Mitsuhiro Fujishiro

    Citation: BMC Gastroenterology 2020 20:81

    Content type: Research article

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  3. The prevalence of malnutrition remains high in hospitals but no “gold standard” has been established to identify nutritional risks adequately. The Nutrition Risk Screening-2002 (NRS-2002), Subjective Global As...

    Authors: Mariana Chávez-Tostado, Gabino Cervantes-Guevara, Sandra Estefanía López-Alvarado, Gabino Cervantes-Pérez, Francisco José Barbosa-Camacho, Clotilde Fuentes-Orozco, Diana Mercedes Hernández-Corona, Tonatiuh González-Heredia, Guillermo Alonso Cervantes-Cardona and Alejandro González-Ojeda

    Citation: BMC Gastroenterology 2020 20:79

    Content type: Research article

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  4. The database used for the NHS Bowel Cancer Screening Programme (BCSP) derives participant information from primary care records. Combining predictors with FOBTs has shown to improve referral decisions and accu...

    Authors: Jennifer Anne Cooper, Ronan Ryan, Nick Parsons, Chris Stinton, Tom Marshall and Sian Taylor-Phillips

    Citation: BMC Gastroenterology 2020 20:78

    Content type: Research article

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  5. There are several studies with varied and mixed results about the possible relationship between H. pylori and diabetes. Therefore, this current meta-analysis performed to determine the association between H. pylo...

    Authors: Kamyar Mansori, Yousef Moradi, Sara Naderpour, Roya Rashti, Ali Baradaran Moghaddam, Lotfolah Saed and Hedyeh Mohammadi

    Citation: BMC Gastroenterology 2020 20:77

    Content type: Research article

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  6. Kaposi’s sarcoma (KS) is a rare vascular tumor associated with human herpesvirus (HHV)-8 infection. One of the variants of KS is defined iatrogenic and is overall reported in transplanted patient but also, alt...

    Authors: Valerio Papa, Maria Cristina Giustiniani, Loris Riccardo Lopetuso and Alfredo Papa

    Citation: BMC Gastroenterology 2020 20:76

    Content type: Case report

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  7. The intestinal epithelial barrier allows absorption of dietary nutrients and prevents passage of pathogens and toxins into the body. Severe insults have a negative impact on the intestinal environment, which m...

    Authors: Masaaki Motoori, Koji Tanaka, Keijiro Sugimura, Hiroshi Miyata, Takuro Saito, Yasuhiro Miyazaki, Kazumasa Fujitani, Yukiko Kado, Takashi Asahara and Masahiko Yano

    Citation: BMC Gastroenterology 2020 20:74

    Content type: Research article

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  8. Short-chain fatty acids (SCFAs) alteration have been reported in irritable bowel syndrome (IBS), but the results are conflicting. Our study aims to explore the alteration of SCFAs in patients with diarrhea-pre...

    Authors: Zhenyi Tian, Xiaojun Zhuang, Mei Luo, Wei Yin and Lishou Xiong

    Citation: BMC Gastroenterology 2020 20:73

    Content type: Research article

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  9. Esophageal intramural pseudodiverticulosis is an uncommon, idiopathic disorder characterized by multiple small outpouchings protruding from the esophageal lumen. Esophageal intramural pseudodiverticulosis is a...

    Authors: Osman Ali, Hazel Asumu, Tanisha Kaur, Angelina Mathew and Raymond Kim

    Citation: BMC Gastroenterology 2020 20:72

    Content type: Case report

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  10. This study aimed to develop prognostic models for predicting 28- and 90-day mortality rates of hepatitis B virus (HBV)-associated acute-on-chronic liver failure (HBV-ACLF) through artificial neural network (AN...

    Authors: Yixin Hou, Qianqian Zhang, Fangyuan Gao, Dewen Mao, Jun Li, Zuojiong Gong, Xinla Luo, Guoliang Chen, Yong Li, Zhiyun Yang, Kewei Sun and Xianbo Wang

    Citation: BMC Gastroenterology 2020 20:75

    Content type: Research article

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  11. Loeys-Dietz syndrome (LDS) is a systemic connective tissue disease (CTD) associated with a predisposition for intestinal inflammation, food allergy, and failure to thrive, often necessitating nutritional suppl...

    Authors: Pamela A. Frischmeyer-Guerrerio, Gretchen MacCarrick, Harry C. Dietz, F. Dylan Stewart and Anthony L. Guerrerio

    Citation: BMC Gastroenterology 2020 20:71

    Content type: Research article

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  12. Endoscopic full-thickness resection (EFTR) is difficult to perform in a retroflexed fashion in the gastric fundus. The present study aims at exploring whether direct EFTR can be a simple, effective and safe pr...

    Authors: Jinlong Hu, Nan Ge, Sheng Wang, Jintao Guo, Xiang Liu, Guoxin Wang and Siyu Sun

    Citation: BMC Gastroenterology 2020 20:70

    Content type: Technical advance

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  13. Meckel’s diverticulum is a remnant of the omphalomesenteric duct. It can lead to intestinal perforation, obstruction and gastrointestinal bleeding. While the internal hernia caused by Meckel’s diverticulum is ...

    Authors: Yang Zhang, Yuchen Guo, Yuanlin Sun and Yuechao Xu

    Citation: BMC Gastroenterology 2020 20:69

    Content type: Case report

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  14. Although prophylactic clip application before polypectomy may prevent postpolypectomy bleeding (PPB), the usefulness of prophylactic clipping in the treatment of large pedunculated polyps is controversial in s...

    Authors: Jae Seung Soh, Myeongsook Seo and Kyung-Jo Kim

    Citation: BMC Gastroenterology 2020 20:68

    Content type: Research article

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  15. Advances in surgical techniques and perioperative care have improved the short- and mid-term postoperative outcomes of patients with Hirschsprung disease (HD). However, the long-term outcomes of these patients...

    Authors: Ying Dai, Yongfang Deng, Yan Lin, Runxian Ouyang and Le Li

    Citation: BMC Gastroenterology 2020 20:67

    Content type: Research article

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  16. Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease nowadays. Changes in diet and lifestyle have led to a dramatic increase in the prevalence of NAFLD around t...

    Authors: Shu-ting Wang, Jing Zheng, He-wei Peng, Xiao-lin Cai, Xin-ting Pan, Hui-quan Li, Qi-zhu Hong and Xian-E Peng

    Citation: BMC Gastroenterology 2020 20:66

    Content type: Research article

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  17. Ineffective antibiotic therapy increases mortality of acute cholangitis. The choice of antibiotics should reflect local resistance patterns and avoid the overuse of broad-spectrum agents. In this study, we ana...

    Authors: Tassilo Kruis, Sarah Güse-Jaschuck, Britta Siegmund, Thomas Adam and Hans-Jörg Epple

    Citation: BMC Gastroenterology 2020 20:65

    Content type: Research article

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  18. Endoscopic retrograde cholangio-pancreatography (ERCP) is commonly performed in the management of pancreatic and biliary disease. Duodenoscopes are specialized endoscopes used to perform ERCP, and inherent to ...

    Authors: Nauzer Forbes, B. Joseph Elmunzer, Thibault Allain, Millie Chau, Hannah F. Koury, Sydney Bass, Paul J. Belletrutti, Martin J. Cole, Emmanuel Gonzalez-Moreno, Ahmed Kayal, Puja Kumar, Rachid Mohamed, Christian Turbide, Andre G. Buret and Steven J. Heitman

    Citation: BMC Gastroenterology 2020 20:64

    Content type: Study protocol

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  19. Pseudoachalasia is a rare disorder which has clinical, radiographic, and manometric findings that are often indistinguishable from primary achalasia. It is usually associated with malignancy. Few reports descr...

    Authors: Marian Dejaeger, Maud Lormans, Eddy Dejaeger and Katleen Fagard

    Citation: BMC Gastroenterology 2020 20:63

    Content type: Case report

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  20. Crigler Najjar type 1 is a rare autosomal recessive condition caused by the absence of UDPGT enzyme due to mutations in the UGT1A1 gene. This enzyme is responsible for elimination of unconjugated bilirubin fro...

    Authors: Sailaja Valmiki, Kiran Kumar Mandapati, Leela Krishna Vamsee Miriyala, Chayarani Chandrashekhar Kelgeri, Mohamed Rela, Naresh P. Shanmugam and Durga Rao Vegulada

    Citation: BMC Gastroenterology 2020 20:62

    Content type: Case report

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  21. Mucormycosis is rare, life-threatening fungal infection. Frequently observed in those patients having underlying immunosuppression such as, diabetes, organ transplantation, Human immunodeficiency virus (HIV) i...

    Authors: Abdi Bati Wotiye, Poornachandra KS and Biniyam Alemayehu Ayele

    Citation: BMC Gastroenterology 2020 20:61

    Content type: Case report

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  22. Endoscopic mucosal resection (EMR) is a minimally invasive procedure used for the treatment of lesions in the gastrointestinal (GI) tract. There is increased usage of hemoclips during EMR for the prevention of...

    Authors: Karen Chang, Brian S. Lee, Timnit Tekeste, Andrew Nguyen, Mopelola Adeyemo, Agathon Girgis, Karl K. Kwok, H. Michael Crowson, Alicia O. Burris, Rajeev Attam, Charles T. Chaya, Theodore E. Durbin, Andrew Q. Giap, Gordon C. Hunt, John Iskander, Kevin T. Kao…

    Citation: BMC Gastroenterology 2020 20:60

    Content type: Research article

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  23. The gut microbiota participates in the metabolism of substances and energy, promotes the development and maturation of the immune system, forms the mucosal barrier, and protects the host from pathogen attacks....

    Authors: Qiang Wang, Chenjun Hao, Wenchao Yao, Defu Zhu, Haifeng Lu, Long Li, Biao Ma, Bei Sun, Dongbo Xue and Weihui Zhang

    Citation: BMC Gastroenterology 2020 20:59

    Content type: Research article

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  24. Prognostic value or clinical implications of fluid status monitoring in liver cirrhosis are not fully elucidated. Tolvaptan, an orally available, selective vasopressin V2-receptor antagonist approved for hypon...

    Authors: Shunsuke Shiba, Po-sung Chu, Nobuhiro Nakamoto, Karin Yamataka, Nobuhito Taniki, Keisuke Ojiro, Akihiro Yamaguchi, Rei Morikawa, Aya Yoshida, Akihiko Ikura, Hirotoshi Ebinuma, Hidetsugu Saito and Takanori Kanai

    Citation: BMC Gastroenterology 2020 20:53

    Content type: Research article

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  25. The implication of microscopic ileitis finding in patients referred for ileocolonoscopy for clinically suspected inflammatory bowel disease (IBD) is not well defined, and its correlation with clinical outcome ...

    Authors: Fadi Abu Baker, Jesus Alonso Z’cruz De La Garza, Smadar Nafrin, Amir Mari, Muhammed Suki, Baruch Ovadia, Oren Gal and Yael Kopelamn

    Citation: BMC Gastroenterology 2020 20:52

    Content type: Research article

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  26. Lymph node (LN) metastasis is negligible in early gastric cancer (EGC) within expanded criteria for endoscopic submucosal dissection (ESD). However, regional lymph nodes in abdominal CT scans are sometimes enl...

    Authors: Dong Seok Lee, Jong Kyu Park, Sang Jin Lee and Gab Jin Cheon

    Citation: BMC Gastroenterology 2020 20:51

    Content type: Research article

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  27. We investigated real-world effectiveness and safety of sofosbuvir and the nonstructural protein 5A inhibitors in the treatment of patients infected with hepatitis C virus (HCV) genotypes 1, 2, 3, 4, or 6.

    Authors: Phunchai Charatcharoenwitthaya, Virasak Wongpaitoon, Piyawat Komolmit, Wattana Sukeepaisarnjaroen, Pisit Tangkijvanich, Teerha Piratvisuth, Theeranun Sanpajit, Chinnavat Sutthivana, Chalermrat Bunchorntavakul, Abhasnee Sobhonslidsuk, Soonthorn Chonprasertsuk, Chotipong Siripipattanamongkol, Supatsri Sethasine and Tawesak Tanwandee

    Citation: BMC Gastroenterology 2020 20:47

    Content type: Research article

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  28. Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Within the spectrum of NAFLD, non-alcoholic steatohepatitis (NASH) in combination with hepatic inflammation and fibro...

    Authors: Atsuko Takai, Kentaro Kikuchi, Mayuko Ichimura, Koichi Tsuneyama, Yuki Moritoki, Kotaro Matsumoto, Hiromichi Tsunashima, Takeshi Onda, Noriyuki Kuniyoshi, Tomoyuki Nariyama, Sho Ohyatsu, Juri Kubota, Kozue Nagumo, Shinpei Sato, Masumi Hara and Hiroshi Miyakawa

    Citation: BMC Gastroenterology 2020 20:46

    Content type: Research article

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  29. Gastroesophageal reflux disease (GORD) is a chronic and a common condition worldwide which causes mild to severe symptoms. Private tuition attendees are a group which could have potential risk factors for GORD...

    Authors: Darsha Gunasinghe, Chathurika Gunawardhana, Shakthi Halahakoon, Ali Haneeka, Najiyya Hanim, Chamara Hapuarachchi and Devarajan Rathish

    Citation: BMC Gastroenterology 2020 20:45

    Content type: Research article

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  30. Owing to the development of double-balloon enteroscopy (DBE) and video capsule endoscopy (VCE) in recent years, direct visualization of the entire small intestinal mucosa has become possible. Because of the no...

    Authors: Zihan Huang, Xiang Liu, Fei Yang, Guoxin Wang, Nan Ge, Sheng Wang, Jintao Guo and Siyu Sun

    Citation: BMC Gastroenterology 2020 20:42

    Content type: Research article

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  31. The level and profiles of blood free carnitine and acylcarnitines, obtained by acylcarnitine analysis using tandem mass spectrometry, reflect various metabolic conditions. We aimed to examine the level of free...

    Authors: Hisamitsu Miyaaki, Hironori Kobayashi, Satoshi Miuma, Masanori Fukusima, Ryu Sasaki, Masafumi Haraguchi and Kazuhiko Nakao

    Citation: BMC Gastroenterology 2020 20:41

    Content type: Research article

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  32. Hyperuricemia is a major risk for non-alcoholic fatty liver disease. However, the mechanisms for this phenomenon are not fully understood. This study aimed to investigate whether microRNAs mediated the pathoge...

    Authors: Shenghui Chen, Dan Chen, Hua Yang, Xinyu Wang, Jinghua Wang and Chengfu Xu

    Citation: BMC Gastroenterology 2020 20:39

    Content type: Research article

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  33. Following publication of the original article [1], we have been notified that the given name of one of the authors was spelled incorrectly.

    Authors: Pengzi Zhang, Wenhuan Feng, Xuehui Chu, Xitai Sun, Dalong Zhu and Yan Bi

    Citation: BMC Gastroenterology 2020 20:38

    Content type: Correction

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    The original article was published in BMC Gastroenterology 2019 19:202

  34. Gastric schwannomas are rare benign tumors originating from the intramuscular plexus of the stomach and account for just 2.6% of gastric mesenchymal tumors. Gastric schwannoma (GS) with a surface ulcer is very...

    Authors: Caihua Tang, Qiyong Pan, Zeqing Xu, Xuan Zhou and Ying Wang

    Citation: BMC Gastroenterology 2020 20:36

    Content type: Case report

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  35. Effective control of the inflammatory process in Crohn’s disease (CD) is reflected in intestinal mucosal healing. The performances of faecal calprotectin (fcal), clinical and serologic parameters in the inflam...

    Authors: Francisco Guilherme Cancela e Penna, Rodrigo Macedo Rosa, Pedro Ferrari Sales da Cunha, Stella Cristina Silva de Souza and Maria de Lourdes de Abreu Ferrari

    Citation: BMC Gastroenterology 2020 20:35

    Content type: Research article

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  36. Gastrointestinal system (GIS) malignancy with pregnancy is a very rare condition and is not common outside Japan. The incidence is between 0.025–0.1% for each pregnancy. GIS malignancies are diagnosed late in ...

    Authors: Mustafa Yildiz, Yesim Akgun, Hale Ozer and Veli Mihmanli

    Citation: BMC Gastroenterology 2020 20:33

    Content type: Case report

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  37. Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. Studies have shown that sleep apnea is associated with NAFLD. However, studies on the association between sleep disord...

    Authors: Yu-Ting Wei, Peng-Yi Lee, Cheng-Yu Lin, Hsuan-Ju Chen, Che-Chen Lin, Jin-Shang Wu, Yin-Fan Chang, Chen-Long Wu and How-Ran Guo

    Citation: BMC Gastroenterology 2020 20:32

    Content type: Research article

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  38. The association between natural killer (NK) cells and survival in colorectal cancer (CRC) patients remains controversial. This study aimed to clarify the prognostic value of peripheral blood NK cells in CRC pa...

    Authors: Yan-ping Tang, Ming-zhi Xie, Ke-zhi Li, Ji-lin Li, Zheng-min Cai and Bang-li Hu

    Citation: BMC Gastroenterology 2020 20:31

    Content type: Research article

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  39. One major etiology of hepatic sinusoidal obstruction syndrome (HSOS) in China is the intake of pyrrolizidine alkaloids (PAs). Since PAs-induced HSOS is a rare disease that has not been clearly characterized un...

    Authors: Fang Liu, Xinxin Rong, Hui Guo, Dong Xu, Chang Liu, Lingling Meng, Xiaoqian Yang, Tingting Guo, Xuefeng Kan and Yuhu Song

    Citation: BMC Gastroenterology 2020 20:30

    Content type: Research article

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  40. Irritable bowel syndrome (IBS) is a common disease that affects the quality of life (QOL) and social functioning of sufferers. Visceral anxiety is currently considered a key factor in the onset and exacerbatio...

    Authors: Shino Kikuchi, Yuki Oe, Yohei Sasaki, Hirono Ishii, Yuri Ito, Masaru Horikoshi, Takashi Sozu, Hiroshi Seno and Toshi A. Furukawa

    Citation: BMC Gastroenterology 2020 20:29

    Content type: Study protocol

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  41. Patients with inflammatory bowel disease (IBD) tend to avoid dairy products to minimize abdominal pain and diarrhea. The aim of this study was to estimate the proportion of protein from dairy sources (PPDS) in...

    Authors: May-Bente Bengtson, Margaretha Haugen, Anne Lise Brantsæter, Geir Aamodt and Morten H. Vatn

    Citation: BMC Gastroenterology 2020 20:28

    Content type: Research article

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  42. Monopolar instruments are generally used in colorectal endoscopic mucosal resection (EMR). Bipolar instruments have previously been reported to be as safe as monopolar instruments. We sought to compare the saf...

    Authors: Kensuke Shinmura, Hiroaki Ikematsu, Motohiro Kojima, Hiroshi Nakamura, Shozo Osera, Yusuke Yoda, Keisuke Hori, Yasuhiro Oono, Atsushi Ochiai and Tomonori Yano

    Citation: BMC Gastroenterology 2020 20:27

    Content type: Research article

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  43. Hemodialysis patients are prone to constipation, which can adversely affect their quality of life (QOL). Elobixibat, a highly selective inhibitor of the ileal bile acid transporter, can increase the bile acid ...

    Authors: Daigo Kamei, Yuiko Kamei, Masashi Nagano, Michio Mineshima, Kosaku Nitta and Ken Tsuchiya

    Citation: BMC Gastroenterology 2020 20:26

    Content type: Research article

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  44. Naldemedine, a novel peripherally-acting mu-opioid receptor antagonist, has improved opioid-induced constipation in randomized controlled trials. The most frequent adverse event of naldemedine is diarrhea, whi...

    Authors: Yusuke Takagi, Gakuji Osawa, Yoriko Kato, Eri Ikezawa, Chika Kobayashi and Etsuko Aruga

    Citation: BMC Gastroenterology 2020 20:25

    Content type: Research article

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  45. Chronic hepatitis delta virus (HDV) infection causes severe liver disease which often leads to cirrhosis and hepatocellular carcinoma (HCC). Aim of this study was to establish the disease severity and prognost...

    Authors: Jan-Hendrik Bockmann, Marcel Grube, Vanessa Hamed, Johann von Felden, Johanna Landahl, Malte Wehmeyer, Katja Giersch, Michaela T. Hall, John M. Murray, Maura Dandri, Stefan Lüth, Ansgar W. Lohse, Marc Lütgehetmann and Julian Schulze Zur Wiesch

    Citation: BMC Gastroenterology 2020 20:24

    Content type: Research article

    Published on:

  46. Gastrointestinal (GI) cytomegaloviral (CMV) infection is common among patients with immunocompromised status; however, data specific to GI-CMV infection in immunocompetent patients are comparatively limited.

    Authors: Thanaboon Chaemsupaphan, Julajak Limsrivilai, Chenchira Thongdee, Asawin Sudcharoen, Ananya Pongpaibul, Nonthalee Pausawasdi and Phunchai Charatcharoenwitthaya

    Citation: BMC Gastroenterology 2020 20:22

    Content type: Research article

    Published on:

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