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  1. MicroRNAs (miRNAs) play an important role in various diseases, including HCV infection, the aim of the current study was to evaluate the potential use of serum miRNAs as biomarkers for diagnosis, prognosis, an...

    Authors: Noha Anwar Hassuna, Aya Nabil Gamil, Mahmoud Shokry Mahmoud, Wafaa Khairy Mohamed and Rasha Khairy
    Citation: BMC Gastroenterology 2022 22:499
  2. No study has performed a face-to-face comparison of biologics after the failure of the first anti-TNF agent in patients with Crohn’s disease (CD). The aim of the study was to compare the efficacy of biologics ...

    Authors: Rayer Cassandra, Maria Nachury, Bourreille Arnaud, Roblin Xavier, Peyrin-Biroulet Laurent, Viennot Stephanie, Flamant Mathurin, Laharie David, Caron Bénédicte, Dewitte Marie, Siproudhis Laurent, Fumery Mathurin and Bouguen Guillaume
    Citation: BMC Gastroenterology 2022 22:498
  3. Endoscopic retrograde cholangiopancreatography (ERCP) in patients with situs inversus totalis (SIT) is rarely understood due to its rarity. Patient position and endoscope manipulation were the main concerns in...

    Authors: Bin Ding, Jun Wang, Xing Wei, Yu Du, Liang Xia, Chenyi Sun, Kun Han, Xue Yang, Xuegang Guo, Yanglin Pan and Xiangping Wang
    Citation: BMC Gastroenterology 2022 22:497
  4. CF patients experience several episodes of pulmonary exacerbations and reduction in their lung function progressively. Lung function is not the only diagnostic index by physicians to decide if CF patients requ...

    Authors: Farid Imanzadeh, Fatemeh Kerami, Maryam Hassanzad, Amirhossein Hosseini, Mahmoud Hajipour, Ghamartaj Khanbabaee, Naghi Dara, Katayoun Khatami, Nazanin Farahbakhsh and Aliakbar Sayyari
    Citation: BMC Gastroenterology 2022 22:494
  5. Gastrointestinal cancers are a critical global cancer burden, and tracking their trends would inform the health policies.

    Authors: Danfeng Yu, Zejin Ou, Wenni Zhang, Huan He, Yongzhi Li, Wenqiao He, Minyi Zhang, Yuhan Gao, Fei Wu and Qing Chen
    Citation: BMC Gastroenterology 2022 22:493
  6. Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is one of the most frequent gastrointestinal disorders worldwide. Although the actual etiology of IBD remains unclear, growin...

    Authors: Dongjie Li, Liyuan Liu, Xiancai Du, Wen Ma, Jing Zhang and Wenhua Piao
    Citation: BMC Gastroenterology 2022 22:492
  7. Although eradication therapy for chronic Helicobacter pylori (H. pylori) reduces the risk of gastric cancer (GC), its effectiveness is not complete. Therefore, it is also critically important to identifying those...

    Authors: Yuka Hirashita, Masahide Fukuda, Masaaki Kodama, Yoshiyuki Tsukamoto, Tadayoshi Okimoto, Kazuhiro Mizukami, Yoshinari Kawahara, Yasuhiro Wada, Sotaro Ozaka, Kazumi Togo, Keisuke Kinoshita, Takafumi Fuchino, Kensuke Fukuda, Kazuhisa Okamoto, Ryo Ogawa, Osamu Matsunari…
    Citation: BMC Gastroenterology 2022 22:490
  8. The unknown aetiology of Serrated Polyposis Syndrome (SPS) impedes risk prediction and prevention. We investigated risk factors for SPS, overall and stratified by World Health Organization (WHO)2010 clinical crit...

    Authors: Emma Anthony, Jeanette C. Reece, Elasma Milanzi, Jihoon E. Joo, Sharelle Joseland, Mark Clendenning, Amanda Whelan, Susan Parry, Julie Arnold, Varnika Vijay, Nathan Atkinson, John L. Hopper, Aung K. Win, Mark A. Jenkins, Finlay A. Macrae, Ingrid M. Winship…
    Citation: BMC Gastroenterology 2022 22:489
  9. There are many well-described potential gastrointestinal (GI) side effects of pancreatic resection that can cause patients to suffer from chronic malabsorption, diarrhea, and persistent nausea. These GI sympto...

    Authors: Rebecca Bromley-Dulfano, Auriel T. August, Amy Y. Li, Walter Park and Brendan Visser
    Citation: BMC Gastroenterology 2022 22:488
  10. Inflammatory bowel disease (IBD) is a chronic systemic inflammatory condition that debilitate the quality of life. Multimorbidity, a concept only beginning to emerge in IBD, is defined as two or more comorbidi...

    Authors: Mahmoud H. Mosli, Majid Alsahafi, Mohammad N Alsanea, Faisal Alhasani, Mohammad Ahmed and Omar Saadah
    Citation: BMC Gastroenterology 2022 22:487
  11. Enterocutaneous fistula after removal of the jejunostomy tube leads to multiple problems, such as cosmetic problems, decreased quality of life, electrolyte imbalances, infectious complications, and increased m...

    Authors: Teppei Kamada, Hironori Ohdaira, Keigo Nakashima, Ryo Nishide, Junji Takahashi, Eisaku Ito, Yuichi Nakaseko, Norihiko Suzuki, Masashi Yoshida, Ken Eto and Yutaka Suzuki
    Citation: BMC Gastroenterology 2022 22:486
  12. Ulcerative colitis (UC) is a chronic idiopathic inflammatory disorder affecting the large intestine. Inflammatory biomarkers in UC are nonspecific, simple and cheap biomarker is needed. Our study aimed to expl...

    Authors: Wan Feng, Yajun Liu, Lei Zhu, Luzhou Xu and Hong Shen
    Citation: BMC Gastroenterology 2022 22:485
  13. To date, no study has evaluated trends in the burden of alcohol-induced cirrhosis and other chronic liver diseases based on the Global Burden of Diseases, Injuries, and Risk Factors (GBD) 2019 study. Herein, w...

    Authors: Xiansheng Zhang, Xin Zhang, Meilian Liu, Lin Zhu and Zhuokai He
    Citation: BMC Gastroenterology 2022 22:484
  14. Non-alcoholic simple fatty liver disease patients have very low compliance with almost all types of physical activities. A transtheoretical model-oriented lifestyle modification plan awakens the patient’s cons...

    Authors: Lijuan Li, Kun Hou, Mengya Yuan, Yan Zhang and Yang Zhang
    Citation: BMC Gastroenterology 2022 22:483
  15. Previous studies have reported that the tumor heterogeneity and complex oncogenic mechanisms of proximal and distal colon cancer (CRC) are divergent. Therefore, we aim to analyze the differences between left-s...

    Authors: Mengye Niu, Chengyang Chen, Xian Gao, Yi Guo, Bingzhou Zhang, Xin Wang, Shihao Chen, Xupeng Niu, Chao Zhang, Like Li, Zhongxin Li, Zengren Zhao and Xia Jiang
    Citation: BMC Gastroenterology 2022 22:482
  16. The mesorectum surrounding the rectum provides an ideal substrate for tumour spread. However, preoperative risk assessment is still an issue. This study aimed to investigate the microstructural features of mes...

    Authors: Bao-Lan Lu, Yan Chen, Zi-Qiang Wen, Yi-Yan Liu, Yu-Ru Ma, Yu-Tao Que, Zhi-Wen Zhang, Xue-Han Wu and Shen-Ping Yu
    Citation: BMC Gastroenterology 2022 22:481
  17. Invasive gastrointestinal surgery may be performed as an open or endoscopic procedure, such as laparoscopic semi-colon surgery, laparoscopic appendectomy, laparoscopic gastrectomy, and anal surgery, among othe...

    Authors: Huyen Thi Nguyen, Quynh Thi Huong Bui, Tam Van Vo, Hien Thi Thu Pham and Thong Duy Vo
    Citation: BMC Gastroenterology 2022 22:480
  18. Non-alcoholic fatty liver disease (NAFLD) is usually asymptomatic and lacks a specific biomarker; therefore, many individuals might remain undiagnosed even with advanced liver fibrosis. The aim of this study w...

    Authors: Shunsuke Sato, Hidehiko Kawai, Sho Sato, Hirohiko Iwasaki, Masashi Omori, Yuji Kita, Yuji Ikeda, Takahito Awatsu, Ayato Murata, Gentaro Taniguchi, Yuji Shimada and Takuya Genda
    Citation: BMC Gastroenterology 2022 22:478
  19. The epidemiology of Crohn’s disease (CD) has changed over the past decades, demonstrating a trend toward increased prevalence in developing countries, while in developed countries, its incidence has stabilized...

    Authors: Ahmed Al Qteishat, Kiril Kirov and Dmitry Bokov
    Citation: BMC Gastroenterology 2022 22:477
  20. It has not yet been determined whether gastroscopy and colonoscopy screening help patients with gallbladder diseases. We aim to retrospectively investigate the relationship between gallbladder diseases and gas...

    Authors: Wenbin Geng, Xiangrong Qin, Peng Yang, Junmei Wang, Jing Yu and Xiaoyong Wang
    Citation: BMC Gastroenterology 2022 22:476
  21. The influence of alcoholic liver disease (ALD) on the postoperative outcomes is not completely understood. Our purpose is to evaluate the complications and mortality after nonhepatic surgeries in patients with...

    Authors: Hsin-Yun Wu, Chuen-Chau Chang, Chun-Chieh Yeh, Ming-Yao Chen, Yih-Giun Cherng, Ta-Liang Chen and Chien-Chang Liao
    Citation: BMC Gastroenterology 2022 22:475
  22. Although various treatments help reduce abdominal pain, real-world pain medication utilization among patients with Crohn’s disease (CD) or ulcerative colitis (UC) receiving advanced therapies is poorly underst...

    Authors: Theresa Hunter, April N. Naegeli, Chi Nguyen, Mingyang Shan, Joseph L. Smith, Hiangkiat Tan, Klaus Gottlieb and Keith Isenberg
    Citation: BMC Gastroenterology 2022 22:474
  23. Main pancreatic duct (MPD) dilation is a high-risk stigmata/worrisome feature of malignancy in intraductal papillary mucinous neoplasms (IPMNs). The threshold of MPD diameter in predicting malignancy may be re...

    Authors: Hao Zhou, Xiaoshuang Li, Yajie Wang, Zhiyue Wang, Jingrong Zhu, Zhongqiu Wang and Xiao Chen
    Citation: BMC Gastroenterology 2022 22:473
  24. Little evidence is available in terms of the role of dietary antioxidants in the management of irritable bowel syndrome (IBS) disease. This study aimed to examine the association between dietary total antioxid...

    Authors: Solaleh Saneie, Azadeh Aminianfar, Farzad Shidfar, Ammar Hassanzadeh Keshteli, Ahmad Esmaillzadeh and Peyman Adibi
    Citation: BMC Gastroenterology 2022 22:472
  25. A recently proposed diagnostic criteria of metabolic dysfunction-associated fatty liver disease (MAFLD) is more available for various clinical situations than nonalcoholic fatty liver disease (NAFLD), but unde...

    Authors: Qiling Liu, Gang Zhao, Qian Li, Weiyun Wu, Yan Zhang and Hua Bian
    Citation: BMC Gastroenterology 2022 22:471
  26. The aim of this study was to investigate the efficacy and safety of the combination of low-molecular-weight heparin + dexamethasone after partial splenic embolization in cirrhotic patients with massive splenom...

    Authors: Haohao Lu, Chuansheng Zheng, Bin Xiong and Xiangwen Xia
    Citation: BMC Gastroenterology 2022 22:470
  27. Triclosan, an antimicrobial agent in personal care products, could be absorbed into the human body through the digestive tract. This animal experiment aimed to clarify the effects of triclosan exposure on the ...

    Authors: Jing Liu, Yang Tao, Wang Haikun, Yang Lanfang, Lu Jingyi and Yao Ping
    Citation: BMC Gastroenterology 2022 22:469
  28. The timing of nutritional assessment may be important to treat cancer patients and predict their prognosis. This study examined whether Patient-Generated Subjective Global Assessment (PG-SGA) and NUTRISCORE sc...

    Authors: Jae Won Cho, Jiyoung Youn, Eun Mee Kim, Min-Gew Choi and Jung Eun Lee
    Citation: BMC Gastroenterology 2022 22:468
  29. National Comprehensive Cancer Network HCC guidelines recommend Y90 to treat BCLC-C patients only in select cases given the development of systemic regimens. We sought to identify ideal candidates for Y90 by as...

    Authors: Pulak Goswami, Oladapo R. Adeniran, Shelby K. Frantz, Lea Matsuoka, Liping Du, Ripal T. Gandhi, Zachary S. Collins, Marc R. Matrana, Michael Petroziello, Jayson S. Brower, Daniel Y. Sze, Andrew S. Kennedy, Jafar Golzarian, Eric A. Wang and Daniel B. Brown
    Citation: BMC Gastroenterology 2022 22:467
  30. Given the limited effectiveness of the current Chinese colorectal cancer (CRC) screening procedure, adherence to colonoscopy remains low. We aim to develop and validate a scoring system based on individuals wh...

    Authors: Zhen Yuan, Shuyuan Wang, Zhaoce Liu, Yanfei Liu, Yuqi Wang, Youkui Han, Weifeng Gao, Xinyu Liu, Hongzhou Li, Qinghuai Zhang, Hong Ma, Junying Wang, Xiaomeng Wei, Xipeng Zhang, Wei Cui and Chunze Zhang
    Citation: BMC Gastroenterology 2022 22:466
  31. Gastrointestinal (GI) bleeding is one of the most impactful complications in patients hospitalized from COVID-19 infection. Limited study has focused on patients with upper GI bleeding (UGIB). This study aimed...

    Authors: Thaninee Prasoppokakorn, Pinit Kullavanijaya and Rapat Pittayanon
    Citation: BMC Gastroenterology 2022 22:465
  32. Biological therapy for inflammatory bowel disease is efficient in many cases but not all. The underlying molecular mechanisms behind non-response to biological therapy in inflammatory bowel disease are poorly ...

    Authors: Rasmus Goll, Øystein K. Moe, Kay-Martin Johnsen, Renate Meyer, Joachim Friestad, Mona D. Gundersen, Hege Kileng, Knut Johnsen and Jon R. Florholmen
    Citation: BMC Gastroenterology 2022 22:464
  33. To construct clinical and machine learning nomogram for predicting the lymph node metastasis (LNM) status of rectal carcinoma (RC) based on radiomics and clinical characteristics.

    Authors: Hang Yuan, Xiren Xu, Shiliang Tu, Bingchen Chen, Yuguo Wei and Yanqing Ma
    Citation: BMC Gastroenterology 2022 22:463
  34. To explore the clinical application of a newly developed magnetic anchoring traction (MAT) system in the liver bench trimming and transplantation surgery.

    Authors: Jiashu Song, Yue Wang, Xianming Cai, Jianhua Shi, Liangshuo Hu, Pengkang Chang, Wei Zhang, Bo Tang, Yi Lv and Xiaogang Zhang
    Citation: BMC Gastroenterology 2022 22:462
  35. China is a region with a high incidence of tuberculosis, and the incidence of IBD has also been rising rapidly in recent years. Differentiating Crohn’s disease(CD) from intestinal tuberculosis (ITB) has become...

    Authors: Shaoxiong Zeng, Ying Lin, Jiaxiang Guo, Xi Chen, Qiong Liang, Xiaoming Zhai and Jin Tao
    Citation: BMC Gastroenterology 2022 22:461
  36. Dual-clip and rubber band-assisted endoscopic submucosal dissection (DCRB-ESD) is a useful technique in the management of lateral spreading tumors (LSTs) of the colon and is suggested by researchers compared w...

    Authors: Xingbin Ma, Huaiyuan Ma, Tao Gao, Jingrun Cao, Chengxia Liu and Qiong Niu
    Citation: BMC Gastroenterology 2022 22:460
  37. The long-term outcomes of Ulcerative colitis (UC) after discontinuation of biological therapy are largely unknown. There is also a lack of accurate and validated markers that can predict outcome after withdraw...

    Authors: Kay-Martin Johnsen, Jon Florholmen, Øystein K. Moe, Mona Gundersen, Julia Beilfuss, Hege Kileng, Sveinung W. Sørbye and Rasmus Goll
    Citation: BMC Gastroenterology 2022 22:459
  38. Pancreatic signet ring cell carcinoma (PSRCC) is a rare tumour subtype with poorly understood epidemiological characteristics and prognosis. We attempted to comprehensively characterise the epidemiology and su...

    Authors: Duorui Nie, Qingxia Lan, Yue Huang, Chongkai Fang, Yang Cao and Yao Chen
    Citation: BMC Gastroenterology 2022 22:458
  39. Crohn’s disease (CD), an inflammatory bowel disease (IBD), is a complex and heterogeneous disease characterized by nonspecific transmural inflammation of the gastrointestinal tract. CD has a variety of potenti...

    Authors: Zhangwei Xu, Jason J. Chen, Qiao Mei, Yang Li and Jianming Xu
    Citation: BMC Gastroenterology 2022 22:457
  40. Trans-hepatic arterial chemoembolization (TACE) is a treatment option for liver cancer patients. It can prolong patients’ survival but can also cause symptom distress. Symptom distress (SDs) can directly impac...

    Authors: Nan-Yan Chen, Kang-Hua Chen, Yi-Wen Wang, Hsiu-Hsin Tsai, Wei-Chen Lee and Li-Chueh Weng
    Citation: BMC Gastroenterology 2022 22:456
  41. Due to the low mutational testing rate in patients with Gastrointestinal Stromal Tumors (GIST), The Life Raft Group (LRG), a non-profit organization that provides support, advocacy and conducts research for pa...

    Authors: Denisse Montoya, Jerry W. Call, Jennily Eshak, Pete Knox, Maeven Luedke, Sahibjeet Kaur, Sara Rothschild, Mary Garland and Norman J. Scherzer
    Citation: BMC Gastroenterology 2022 22:455
  42. Transient receptor potential (TRP) channels have high permeability to Ca2+ ions because they are non-selective ion channels. TRP channels have been implicated in tumor onset and progression, proliferation, and mi...

    Authors: Lincheng Li, Zhaohui Xiao, Pengyi He, Wenbo Zou, Zhaoda Deng, Gong Zhang and Rong Liu
    Citation: BMC Gastroenterology 2022 22:454
  43. Metabolic syndrome (MetS) is a worldwide pandemic and complex disorder associated with colorectal cancer (CRC). This study aims to identify the influence of number of MetS components on CRC incidence and morta...

    Authors: Kuan-Chih Chung, Sin-Ei Juang, Hong-Hwa Chen, Kung-Chuan Cheng, Kuen-Lin Wu, Ling-Chiao Song and Ko-Chao Lee
    Citation: BMC Gastroenterology 2022 22:453
  44. Patients with low HBV DNA levels (< 2000 IU/mL), HBV DNA negative, and HBsAg-negative hepatitis B virus(HBV)infection can still progress to decompensated cirrhosis; however, clinical research data in such pati...

    Authors: Xu Huang, Meimei Yan, Zerun Deng, Lei Yao, Dan Han and Lihua Sun
    Citation: BMC Gastroenterology 2022 22:452
  45. The aim of our study was to evaluate the curative effect and safety of stereotactic body radiation therapy (SBRT) in treating hepatocellular carcinoma (HCC) patients with inferior vena cava (IVCTT) and right a...

    Authors: Dan Zhang, Qian Li, Dong Li, Jun Jia, JunQiang Ding, Jing Sun and Xuezhang Duan
    Citation: BMC Gastroenterology 2022 22:451
  46. This study aimed to develop and validate a nomogram to predict the risk of pancreatitis after percutaneous transhepatic biliary stent insertion (PTBS) in patients with malignant biliary obstruction (MBO).

    Authors: Chen Xu, Yiming Gu, Weizhong Zhou, Guoxiong Xu, Sheng Liu and Haibin Shi
    Citation: BMC Gastroenterology 2022 22:449

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