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  1. The World Health Organization's updated classification of digestive system neuroendocrine tumors in 2010 first proposed the classification of mixed adenoneuroendocrine carcinoma (MANEC). The incidence of bilia...

    Authors: Sulai Liu, Zhendong Zhong, Meng Xiao, Yinghui Song, Youye Zhu, Bo Hu, Zengpeng Sun, Weimin Yi and Chuang Peng

    Citation: BMC Gastroenterology 2020 20:399

    Content type: Case report

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  2. We initiated the first multi-center cluster randomized trial of endoscopic screening for esophageal cancer and gastric cancer in China. The objective of the study was to report the baseline screening findings ...

    Authors: Hongmei Zeng, Kexin Sun, Maomao Cao, Rongshou Zheng, Xibin Sun, Shuzheng Liu, Zhiyi Zhang, Yuqin Liu, Guizhou Guo, Guohui Song, Yigong Zhu, Xianghong Wu, Bingbing Song, Xianzhen Liao, Yanfang Chen, Mingyang Song…

    Citation: BMC Gastroenterology 2020 20:398

    Content type: Research article

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  3. The resistance rate of Helicobacter pylori to clarithromycin (CAM) is high among infected children in Japan. Therefore, a new method for detecting CAM-resistant H. pylori using a minimally invasive technique is s...

    Authors: Toshihiko Kakiuchi, Kazutoshi Hashiguchi, Ichiro Imamura, Aiko Nakayama, Ayako Takamori, Masumi Okuda and Muneaki Matsuo

    Citation: BMC Gastroenterology 2020 20:397

    Content type: Technical advance

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  4. There are often specific endoscopic findings caused by deposition of lanthanum (La) in the gastric mucosa of patients taking lanthanum carbonate (LaC), a novel phosphate binder for patients on hemodialysis. We...

    Authors: Shinya Nishida, Kazuhiro Ota, Kimiaki Hattori, Taro Iwatsubo, Shimpei Kawaguchi, Yuichi Kojima, Toshihisa Takeuchi, Tamaki Maeda, Masahiro Sakaguchi and Kazuhide Higuchi

    Citation: BMC Gastroenterology 2020 20:396

    Content type: Research article

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  5. Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that specifically occurs in pregnancy. Elevated levels of liver transaminases aspartate aminotransferase, alanine aminotransferase and serum bili...

    Authors: Rong Li, Xuehai Chen, Zhongzhen Liu, Yan Chen, Chuan Liu, Lingfei Ye, Liang Xiao, Zhenjun Yang, Jian He, Wen-Jing Wang and Hongbo Qi

    Citation: BMC Gastroenterology 2020 20:395

    Content type: Research article

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  6. Tuberous Sclerosis Complex (TSC) is a complex and heterogeneous genetic disease that has well-established clinical diagnostic criteria. These criteria do not include gastrointestinal tumors.

    Authors: Larissa Brussa Reis, Daniele Konzen, Cristina Brinckmann Oliveira Netto, Pedro Moacir Braghirolli Braghini, Gabriel Prolla and Patricia Ashton-Prolla

    Citation: BMC Gastroenterology 2020 20:394

    Content type: Case report

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  7. To investigate the value of serum hydroxybutyrate dehydrogenase (HBDH) level, an isozyme of lactate dehydrogenase, in evaluating the severity of acute pancreatitis (AP).

    Authors: Weiming Xiao, Weili Liu, Ling Yin, Yong Li, Guotao Lu, Xinnong Liu, Weijuan Gong, Yanbing Ding, Mei Wang and Zhigang Yan

    Citation: BMC Gastroenterology 2020 20:393

    Content type: Research article

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  8. An epidermoid cyst in an intrapancreatic accessory spleen (ECIPAS) in the pancreas head is an extremely rare condition. The natural course of this condition is not well known, and it is difficult to diagnose b...

    Authors: Hyo Jung Ko, Jae Ryong Shim, Tae Beom Lee, Byung Hyun Choi, Jung-Hee Lee, Je Ho Ryu and Kwangho Yang

    Citation: BMC Gastroenterology 2020 20:392

    Content type: Case report

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  9. To determine the safety and efficacy of different doses of tolvaptan for treating Chinese cirrhotic patients with or without hyponatraemia who still had ascites after routine therapy with diuretics.

    Authors: Jieting Tang, Yongfeng Wang, Tao Han, Qing Mao, Jun Cheng, Huiguo Ding, Jia Shang, Qin Zhang, Junqi Niu, Feng Ji, Chengwei Chen, Jidong Jia, Xiangjun Jiang, Nonghua Lv, Yueqiu Gao, Zhenghua Wang…

    Citation: BMC Gastroenterology 2020 20:391

    Content type: Research article

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  10. Ultrasound (US) imaging is known to underestimate tumor size in clinical. This study is aimed to compare the size measurements of hepatocellular carcinoma (HCC) in three US imaging modalities, i.e. two-dimensi...

    Authors: Fei Chen, Fei Wang, Si Sun, Mei Zhu and Zheng Liu

    Citation: BMC Gastroenterology 2020 20:390

    Content type: Research article

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  11. The current virtual chromoendoscopy equipment cannot completely detect superficial squamous cell carcinoma (SCC) in the esophagus, despite its development in the recent years. Thus, in this study, we aimed to ...

    Authors: Taro Iwatsubo, Ryu Ishihara, Yasushi Yamasaki, Yusuke Tonai, Kenta Hamada, Minoru Kato, Sho Suzuki, Mitsuhiro Kono, Hiromu Fukuda, Yusaku Shimamoto, Kentaro Nakagawa, Masayasu Ohmori, Masamichi Arao, Kenshi Matsuno, Hiroyoshi Iwagami, Shuntaro Inoue…

    Citation: BMC Gastroenterology 2020 20:389

    Content type: Research article

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  13. The outbreak of COVID-19 and SARS-CoV-2 infection is spreading worldwide as the first coronavirus pandemic. The clinical picture is variable but flu-like symptoms are common with bilateral interstitial pneumon...

    Authors: Luca Elli, Donatella Barisani, Valentina Vaira, Maria Teresa Bardella, Matilde Topa, Maurizio Vecchi, Luisa Doneda, Alice Scricciolo, Vincenza Lombardo and Leda Roncoroni

    Citation: BMC Gastroenterology 2020 20:387

    Content type: Review

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  15. In the correspondence from Abdurrahman et al., they raised three main concerns and critiques of our recently published article entitled “Syphilitic hepatitis: a case report and review of the literature”. First...

    Authors: Jiaofeng Huang, Bo Wan, Mingfang Wang, Yueyong Zhu and Su Lin

    Citation: BMC Gastroenterology 2020 20:385

    Content type: Correspondence

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    The original article was published in BMC Gastroenterology 2020 20:379

  16. Mucosal healing (MH) has been indicated as the therapeutic goal for ulcerative colitis (UC). Platelet count is known as an inflammation evaluation. However, the association between platelet count and MH among ...

    Authors: Shinya Furukawa, Sen Yagi, Kana Shiraishi, Kenichirou Mori, Tomoyuki Ninomiya, Keitarou Kawasaki, Yuji Mizukami, Seiyuu Suzuki, Masayoshi Uraoka, Naozumi Shibata, Sanae Nakamura, Satoshi Imamine, Hidehiro Murakami, Katsuhisa Ohashi, Masamoto Torisu, Aki Hasebe…

    Citation: BMC Gastroenterology 2020 20:384

    Content type: Research article

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  17. Development of gastrointestinal (GI) complications is adversely associated with prognosis in the critically ill. However, little is known about their impact on the outcome of non-critically ill patients. In th...

    Authors: Chun-Ta Huang, Chun-Ming Hong, Yi-Ju Tsai, Wang-Huei Sheng and Chong-Jen Yu

    Citation: BMC Gastroenterology 2020 20:383

    Content type: Research article

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  18. Amplification of HER2 gene (ERBB2) and overexpression of HER2 protein on cancer cells are found in 10–26% of gastric cancer (GC) and esophagogastric junction cancer (EGJC). Gene copy number variation (CNV) could ...

    Authors: Anna Grenda, Kamila Wojas-Krawczyk, Tomasz Skoczylas, Paweł Krawczyk, Jadwiga Sierocińska-Sawa, Grzegorz Wallner and Janusz Milanowski

    Citation: BMC Gastroenterology 2020 20:382

    Content type: Research article

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  19. Lipid profiles are declined in patients with viral liver cirrhosis and correlated with severity of liver disease. Hepatitis B virus (HBV) is the leading cause of liver cirrhosis in China. Our primary aim was t...

    Authors: Ran Cheng, Ning Tan, Qian Kang, Hao Luo, Hongyu Chen, Jiali Pan, Yifan Han, Yuqing Yang and Xiaoyuan Xu

    Citation: BMC Gastroenterology 2020 20:381

    Content type: Research article

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  21. Syphilis is a sexuality transmitted disease caused by Treponema pallidum. Liver involvement is very rarely seen and occurs in the second phase of the disease. Syphilitic hepatitis generally is mild clinical condi...

    Authors: Abdurrahman Kaya and Sibel Yıldız Kaya

    Citation: BMC Gastroenterology 2020 20:379

    Content type: Correspondence

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    The original article was published in BMC Gastroenterology 2019 19:191

    The Correspondence to this article has been published in BMC Gastroenterology 2020 20:385

  22. Hepatic artery dissection after liver transplantation is an uncommon morbidity. The onset mechanism and management for this disorder remain unclear. The present report describes the cases of two patients with ...

    Authors: Keita Shimata, Yasuhiko Sugawara, Tomoaki Irie, Yuzuru Sambommatsu, Masashi Kadohisa, Sho Ibuki, Seiichi Kawabata, Kaori Isono, Masaki Honda, Hidekazu Yamamoto and Taizo Hibi

    Citation: BMC Gastroenterology 2020 20:378

    Content type: Case report

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  23. We aimed to characterize the trends of prognosis in ulcerative colitis (UC) and Crohn’s disease (CD) in a Chinese tertiary hospital.

    Authors: Hong Lv, Meng Jin, Huimin Zhang, Xuanfu Chen, Meixu Wu, Mingyue Guo, Runing Zhou, Zheng Wang, Hong Yang and Jiaming Qian

    Citation: BMC Gastroenterology 2020 20:377

    Content type: Research article

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  24. The risk of recurrent colonic adenoma associated with high-grade dysplasia (HGD) colon polyps at baseline colonoscopy remains unclear. We conducted a clinical cohort study with patients who underwent polypecto...

    Authors: Jia-Jang Chang, Cheng-Hung Chien, Shuo-Wei Chen, Li-Wei Chen, Ching-Jung Liu and Cho-Li Yen

    Citation: BMC Gastroenterology 2020 20:376

    Content type: Research article

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  25. Portal vein thrombosis (PVT) occurs frequently in hepatocellular carcinoma (HCC) and is often diagnosed in the course of a routine patient evaluation and surveillance for liver cancer. The purpose of this stud...

    Authors: Giulia Malaguarnera, Vito Emanuele Catania, Saverio Latteri, Antonio Maria Borzì, Gaetano Bertino, Roberto Madeddu, Filippo Drago and Michele Malaguarnera

    Citation: BMC Gastroenterology 2020 20:375

    Content type: Research article

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  26. The role of common bile duct (CBD) stenting in the establishment of bile stream in the elderly patients and the ones who are not good candidates for surgery due to not responding to treatments was well documen...

    Authors: Ahmad Hormati, Mohammad Reza Ghadir, Seyed Saeed Sarkeshikian, Faezeh Alemi, Majid Moghaddam, Sajjad Ahmadpour, Abolfazl Mohammadbeigi and Gholam Reza Sivandzadeh

    Citation: BMC Gastroenterology 2020 20:374

    Content type: Research article

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  27. The microsatellite instability (MSI) in colorectal cancer (CRC) has a more favorable clinical outcome and is characterized by highly upregulated expression of various immunological checkpoints than microsatell...

    Authors: Wen-juan Huang, Xin Wang, Meng-lin Zhang, Li Li and Rui-tao Wang

    Citation: BMC Gastroenterology 2020 20:373

    Content type: Research article

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  28. Inflammatory bowel disease (IBD) is a debilitating chronic disease with limited treatment options. Resistant starches may represent a novel treatment for IBD. However, its efficacy and safety remain unclear. O...

    Authors: Joshua Montroy, Rania Berjawi, Manoj M. Lalu, Eyal Podolsky, Cayden Peixoto, Levent Sahin, Alain Stintzi, David Mack and Dean A. Fergusson

    Citation: BMC Gastroenterology 2020 20:372

    Content type: Research article

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  29. Sarcopenia is a syndrome characterized by progressive and systemic decreases in skeletal muscle mass and muscle strength. The influence or prognosis of various liver diseases in this condition have been widely...

    Authors: Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, Kentaro Tanaka, Satoshi Narahara, Takayuki Tokunaga, Takeshi Kawasaki, Yoko Yoshimaru, Katsuya Nagaoka, Takehisa Watanabe, Hiroko Setoyama, Yutaka Sasaki and Yasuhito Tanaka

    Citation: BMC Gastroenterology 2020 20:371

    Content type: Research article

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  30. Despite zinc finger and BTB domain-containing 7A (ZBTB7A) documented importance in multiple tumors, the function and clinical value in Colorectal cancer (CRC) remain elusive. The aim of this study was to evalu...

    Authors: Li Wang, Meng-Xia Zhang, Mei-Fang Zhang and Zi-Wei Tu

    Citation: BMC Gastroenterology 2020 20:370

    Content type: Research article

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  32. The prognostic factors of morbidity and mortality in patients with lean NAFLD (body mass index < 25.0 kg/m2) are unknown.

    Authors: Soichi Iritani, Norio Akuta, Yusuke Kawamura, Akira Kajiwara, Kayoko Kasuya, Shunichiro Fujiyama, Hitomi Sezaki, Tetsuya Hosaka, Masahiro Kobayashi, Mariko Kobayashi, Satoshi Saito, Fumitaka Suzuki, Yasuji Arase, Kenji Ikeda, Yoshiyuki Suzuki and Hiromitsu Kumada

    Citation: BMC Gastroenterology 2020 20:368

    Content type: Research article

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  33. Using fluorescence in situ hybridisation (FISH) to detect any gain of chromosomes 3, 7, or 17 and loss of the 9p21 locus has been proven to be sensitive in the diagnosis of pancreatobiliary tumors. However, bo...

    Authors: Xiaohong Pu, Hongwei Zheng, Xin Yang, Qing Ye, Zhiwen Fan, Jun Yang, Xiangshan Fan, Xiaoping Zhou, Yudong Qiu, Qin Huang, Hongyan Wu and Jun Chen

    Citation: BMC Gastroenterology 2020 20:367

    Content type: Research article

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  34. The occurrence of non-alcoholic fatty liver disease (NAFLD) is found to be higher in patients with obstructive sleep apnea (OSA), which is characterized by intermittent hypoxia. Activation of hypoxia-inducible...

    Authors: Xiaofang Zhang, Caoxin Huang, Xuejun Li, Zhaoshui Shangguan, Wenjing Wei, Suhuan Liu, Shuyu Yang and Yijie Liu

    Citation: BMC Gastroenterology 2020 20:366

    Content type: Research article

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  35. Nasogastric intubation (NGI) is usually challenging in patients under general anesthesia, with reported success rate at the first attempt to be less than 50%. The aim of this study was to investigate whether a...

    Authors: Ting-Yang Huang, Jr-Rung Lin and Yung-Tai Chung

    Citation: BMC Gastroenterology 2020 20:365

    Content type: Research article

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  36. A full spectrum of video capsule endoscopy (VCE) adverse events over the past two decades has not been evaluated. We aimed to determine pooled rates, predictors and temporal-trend of VCE adverse events over th...

    Authors: Yuan-Chen Wang, Jun Pan, Ya-Wei Liu, Feng-Yuan Sun, Yang-Yang Qian, Xi Jiang, Wen-Bin Zou, Ji Xia, Bin Jiang, Nan Ru, Jia-Hui Zhu, En-Qiang Linghu, Zhao-Shen Li and Zhuan Liao

    Citation: BMC Gastroenterology 2020 20:364

    Content type: Research article

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  37. The development of gallbladder disease (GBD) is related to bile acid (BA) metabolism, and the rate of BA circulation increases the risk of biliary cancer. However, it is unclear whether patterns of circulating...

    Authors: Linshi Wu, Yinping Wang, Sibo Zhu, Xunxia Bao, Zhiliang Fu, Timing Zhen, Zhiqing Yuan, Qiwei Li, Zheng Deng, Jianhua Sun and Tao Chen

    Citation: BMC Gastroenterology 2020 20:363

    Content type: Research article

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  38. A care pathway for nonalcoholic fatty liver disease (NAFLD) in Kaiser Permanente San Diego, California was instituted in August 2017 to improve efficiency of disease staging and promote lifestyle modification.

    Authors: Heather Patton, Raoul Burchette, Stephanie Tovar, Jose Pio, Jiaxiao Shi and Lisa M. Nyberg

    Citation: BMC Gastroenterology 2020 20:362

    Content type: Research article

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  39. Gastric varices are encountered less frequently than esophageal varices. Nonetheless, gastric variceal bleeding is more severe and associated with worse outcomes. Conventionally, gastric varices have been desc...

    Authors: Cyriac Abby Philips, Rizwan Ahamed, Sasidharan Rajesh, Tom George, Meera Mohanan and Philip Augustine

    Citation: BMC Gastroenterology 2020 20:361

    Content type: Review

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  40. The prison population is considered at high risk of acquiring infectious diseases due to confined conditions, behavioral factors, injection drug use, unprotected sexual activity, non-professional tattooing and...

    Authors: Ifeyinwa M. Okafor, Solomon O. Ugwu and Henshaw U. Okoroiwu

    Citation: BMC Gastroenterology 2020 20:360

    Content type: Research article

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  41. To develop the Patient Health Questionnaire-8 (PHQ-8) as a more reliable approach than the Somatic Symptom Scale-8 (SSS-8), evaluating somatization which might be a critical factor influencing the quality of l...

    Authors: Chaoqun Yuan, Guizhen Yong, Xi Wang, Ting Xie, Chunyan Wang, Yuan Yuan and Guobin He

    Citation: BMC Gastroenterology 2020 20:359

    Content type: Research article

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  42. Thymic carcinoma is a rare mediastinal neoplasm with a high malignant potential. It often shows pleural invasion and distant metastasis. The metastasis of thymic carcinoma to the small intestine is rarely repo...

    Authors: Yi Yuan, Hong Pu, Ming-hui Pang, Yi-sha Liu and Hang Li

    Citation: BMC Gastroenterology 2020 20:358

    Content type: Case report

    Published on:

  43. Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a vasculitis that mostly occurs in young children. Adult-onset KD (AKD) is rare and often misdiagnosed. Here we report a rare case of KD with chole...

    Authors: Massimo Gallerani, Marco Pala, Fabio Fabbian and Alfredo De Giorgi

    Citation: BMC Gastroenterology 2020 20:357

    Content type: Case report

    Published on:

  44. With more prevalent gastroesophageal reflux disease comes increased cases of Barrett's esophagus and esophageal adenocarcinoma. Image-enhanced endoscopy using linked-color imaging (LCI) differentiates between ...

    Authors: Tsutomu Takeda, Daisuke Asaoka, Daiki Abe, Maiko Suzuki, Yuta Nakagawa, Hitoshi Sasaki, Yoshihiro Inami, Muneo Ikemura, Hisanori Utsunomiya, Shotaro Oki, Nobuyuki Suzuki, Atsushi Ikeda, Noboru Yatagai, Hiroyuki Komori, Yoichi Akazawa, Kohei Matsumoto…

    Citation: BMC Gastroenterology 2020 20:356

    Content type: Research article

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  45. Diarrhea is a common adverse event of fluoropyrimidine-based chemotherapy. However, limited data are available on the frequency and risk factors of complicated chemotherapy-induced diarrhea (CID) and small int...

    Authors: Miho Sakumura, Takayuki Ando, Ayumu Hosokawa, Takahiko Nakajima, Iori Motoo, Hiroshi Mihara, Akira Ueda, Shinya Kajiura, Sohachi Nanjo, Haruka Fujinami, Kohei Ogawa and Ichiro Yasuda

    Citation: BMC Gastroenterology 2020 20:355

    Content type: Research article

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  46. Placement of feeding jejunostomy (PFJ) during esophagectomy is an effective method to maintain adequate nutrition, but is associated with serious complications such as bowel obstruction and jejunal torsion. Th...

    Authors: Teppei Kamada, Hironori Ohdaira, Hideyuki Takeuchi, Junji Takahashi, Rui Marukuchi, Eisaku Ito, Norihiko Suzuki, Satoshi Narihiro, Sojun Hoshimoto, Masashi Yoshida, Mitsuyoshi Urashima and Yutaka Suzuki

    Citation: BMC Gastroenterology 2020 20:354

    Content type: Research article

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  47. Eosinophilic gastrointestinal disorders (EGIDs) are a rare group of inflammatory disorders that can occur anywhere along the gastrointestinal tract, from the esophagus to the rectum. In particular, those with ...

    Authors: Ryo Ataka, Hirokazu Tanaka, Shintaro Yagi, Kei Yamane, Kenji Yoshino, Tomoyuki Miyauchi, Tomoaki Yoh, Keiichi Arafuka, Shinichi Fujita, Akihiko Hamada, Bunji Endo and Shinji Uemoto

    Citation: BMC Gastroenterology 2020 20:353

    Content type: Case report

    Published on:

  48. Kawasaki Disease (KD) is the most common paediatric vasculitis affecting small to medium arteries. Although the average age of diagnosis is 3.4 years with a well-defined clinical presentation, older patients w...

    Authors: Krishan Pratap, Logan S. Gardner, David Gillis, Martin Newman, Dana Wainwright and Roger Prentice

    Citation: BMC Gastroenterology 2020 20:352

    Content type: Case report

    Published on:

  49. Early gastric carcinoma is heterogeneous and can be divided into early gastric cardiac carcinoma (EGCC) and early gastric non-cardiac carcinoma (EGNCC) groups. At present, differences in clinicopathology remai...

    Authors: Yaohui Wang, Xiuqing Li, Lili Gao, Chenxi Wang, Yifen Zhang and Qin Huang

    Citation: BMC Gastroenterology 2020 20:351

    Content type: Research article

    Published on:

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