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  1. Fecal calprotectin (FCP), magnetic resonance enterography (MRE), and colonoscopy are complementary biometric tests that are used to assess patients with Crohn’s Disease (CD). While prior studies have evaluated...

    Authors: Alexander S. Somwaru, Vikesh Khanijow and Venkat S. Katabathina

    Citation: BMC Gastroenterology 2019 19:210

    Content type: Research article

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  2. Clear evidence on the benefit-harm balance and cost effectiveness of population-based screening for colorectal cancer (CRC) is missing. We aim to systematically evaluate the long-term effectiveness, harms and ...

    Authors: Beate Jahn, Gaby Sroczynski, Marvin Bundo, Nikolai Mühlberger, Sibylle Puntscher, Jovan Todorovic, Ursula Rochau, Willi Oberaigner, Hendrik Koffijberg, Timo Fischer, Irmgard Schiller-Fruehwirth, Dietmar Öfner, Friedrich Renner, Michael Jonas, Monika Hackl, Monika Ferlitsch…

    Citation: BMC Gastroenterology 2019 19:209

    Content type: Research article

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  3. Heparin bridging therapy (HBT) is indeed related to a high frequency of bleeding after endoscopic mucosal resection (EMR). In this study, our aim was to investigate clinical impact of management of oral antico...

    Authors: Shoko Ono, Marin Ishikawa, Kana Matsuda, Momoko Tsuda, Keiko Yamamoto, Yuichi Shimizu and Naoya Sakamoto

    Citation: BMC Gastroenterology 2019 19:206

    Content type: Research article

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  4. To determine the indications for adjuvant chemotherapy (AC) in patients with stage IIa gastric cancer (T3N0M0 and T1N2M0) according to the 7th American Joint Committee on Cancer (AJCC).

    Authors: Ze-Ning Huang, Jacopo Desiderio, Qi-Yue Chen, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ju-Li Lin, Hua-Long Zheng and Chang-Ming Huang

    Citation: BMC Gastroenterology 2019 19:205

    Content type: Research article

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  5. Irritable bowel syndrome (IBS) is prevalent in patients with morbid obesity. After Roux-en-Y gastric bypass (RYGB) chronic abdominal pain is common, however the etiology is largely unknown. We aimed to study t...

    Authors: Ingvild Kristine Blom-Høgestøl, Martin Aasbrenn, Monica Chahal-Kummen, Cathrine Brunborg, Inger Eribe, Jon Kristinsson, Per G. Farup and Tom Mala

    Citation: BMC Gastroenterology 2019 19:204

    Content type: Research article

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  6. Bleeding esophageal varices is a deadly complication of liver cirrhosis. Guidelines recommend an early diagnosis of esophageal varices before incident bleeding by screening all patients diagnosed with liver ci...

    Authors: Daniel W. Gunda, Semvua B. Kilonzo, Zakhia Mamballah, Paulina M. Manyiri, David C. Majinge, Hyasinta Jaka, Benson R. Kidenya and Humphrey D. Mazigo

    Citation: BMC Gastroenterology 2019 19:203

    Content type: Research article

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  7. Drug induced liver injury (DILI) is an important cause of acute liver injury and accounts for approximately 10% of all cases of acute hepatitis. Both prescription and natural health products (NHPs) have been i...

    Authors: Tyler Pitre, Jasmine Mah, Jaclyn Vertes, Rosario Rebello and Julie Zhu

    Citation: BMC Gastroenterology 2019 19:199

    Content type: Case report

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  8. This case seeks to highlight to endoscopists a rare benign disorder that may be encountered during endoscopy. Clinicians may be tempted to biopsy, which could lead to a catastrophic gastrointestinal haemorrhage.

    Authors: Kushala W. M. Abeysekera, Daniel S. Pearl, Paul Burn and Andrew Lowe

    Citation: BMC Gastroenterology 2019 19:198

    Content type: Case report

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  9. Pancreatic cavernous hemangioma is an extremely rare benign tumor that is difficult to diagnose on an imaging examination, and its histopathological examination has rarely been reported.

    Authors: Tao Lianyuan, Wang Yafeng, Yu Haibo, Dong Yadong, Ma Jiahao, Lu Yuanxiang and Li Deyu

    Citation: BMC Gastroenterology 2019 19:197

    Content type: Case report

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  10. The available information on granulocyte and monocyte adsorptive apheresis (GMA) in patients with inflammatory bowel disease (IBD) under special situations remains unclear. We conducted a retrospective, multic...

    Authors: Satoshi Motoya, Hiroki Tanaka, Tomoyoshi Shibuya, Taro Osada, Takayuki Yamamoto, Hitoshi Hongo, Chiemi Mizuno, Daisuke Saito, Nobuo Aoyama, Toshihisa Kobayashi, Hiroaki Ito, Satoshi Tanida, Masanori Nojima, Seiichiro Kokuma and Eiji Hosoi

    Citation: BMC Gastroenterology 2019 19:196

    Content type: Research article

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  11. Hyperlipidaemia may be a potential risk factor for the occurrence of intestinal polyps. This study aimed to evaluate correlation between lipidaemia and the formation of colorectal polyps.

    Authors: Chenxi Xie, Pingwu Wen, Jingling Su, Qin Li, Yandan Ren, Yueyu Liu, Renze Shen and Jianlin Ren

    Citation: BMC Gastroenterology 2019 19:195

    Content type: Research article

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  12. Although isolating Glissonean pedicles and hepatic veins are critical procedures during anatomical hepatectomy, there is no standardized approach. We propose the novel Laennec’s approach for laparoscopic anato...

    Authors: Yue Hu, Jiong Shi, Shaohe Wang, Wenjie Zhang, Xitai Sun, Beicheng Sun and Decai Yu

    Citation: BMC Gastroenterology 2019 19:194

    Content type: Research article

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  13. Proton pump inhibitors (PPI) and histamine 2 receptor antagonists (H2RA) have been widely used as stress ulcer prophylaxis (SUP) in critically ill patients, however, its efficacy and safety remain unclear. Thi...

    Authors: Xiaoyang Zhou, Hanyuan Fang, Jianfei Xu, Peifu Chen, Xujun Hu, Bixin Chen, Hua Wang, Caibao Hu and Zhaojun Xu

    Citation: BMC Gastroenterology 2019 19:193

    Content type: Research article

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  14. Endoscopic mucosal resection (EMR) to remove colon polyps is increasingly common in patients taking antithrombotic agents. The safety of EMR with submucosal saline injection has not been clearly demonstrated i...

    Authors: Daisuke Yamaguchi, Hisako Yoshida, Kei Ikeda, Yuki Takeuchi, Shota Yamashita, Amane Jubashi, Takahiro Yukimoto, Eri Takeshita, Wataru Yoshioka, Hiroko Fukuda, Naoyuki Tominaga, Nanae Tsuruoka, Tomohito Morisaki, Keisuke Ario, Seiji Tsunada and Kazuma Fujimoto

    Citation: BMC Gastroenterology 2019 19:192

    Content type: Research article

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  15. Syphilis is a common disease that has been researched and focused on for many years, however, syphilitic hepatitis has not been well-recognized. We report this case of syphilitic hepatitis with intrahepatic chole...

    Authors: Jiaofeng Huang, Su Lin, Mingfang Wang, Bo Wan and Yueyong Zhu

    Citation: BMC Gastroenterology 2019 19:191

    Content type: Case report

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  16. High cecal intubation rate (CIR) is associated with significant improved adenoma detection rate (ADR), however, self-reported CIR may be overestimated and inadequate documentation of cecal intubation is associ...

    Authors: Martin Buerger, Philipp Kasper, Gabriel Allo, Johannes Gillessen and Christoph Schramm

    Citation: BMC Gastroenterology 2019 19:190

    Content type: Research article

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  17. There is an unmet need for novel treatments, such as drugs or vaccines, adjunctive to or replacing a burdensome life-long gluten-free diet for coeliac disease. The gold standard for successful treatment is a h...

    Authors: Juha Taavela, Keijo Viiri, Alina Popp, Mikko Oittinen, Valeriia Dotsenko, Markku Peräaho, Synnöve Staff, Jani Sarin, Francisco Leon, Markku Mäki and Jorma Isola

    Citation: BMC Gastroenterology 2019 19:189

    Content type: Research article

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  18. Hepatic epithelioid hemangioendothelioma (HEH) is rare; it is reported in < 1 person in 1,000,000 individuals. For accurate diagnosis, information regarding multiple graphic modalities in HEH is required. Howe...

    Authors: Jun Arai, Yuu Shimozuma, Yumi Otoyama, Ikuya Sugiura, Yoko Nakajima, Eiichi Hayashi, Atsushi Kajiwara, Risa Omori, Shojiro Uozumi, Miyuki Miyashita, Manabu Uchikoshi, Hiroyoshi Doi, Masashi Sakaki, Tianpeng Wang, Junichi Eguchi, Takayoshi Ito…

    Citation: BMC Gastroenterology 2019 19:187

    Content type: Case report

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  19. Only a paucity of large-scale perspective and cross-sectional studies on H. pylori infection in China have been published. The purpose of this study was to investigate the prevalence and risk factors for H. pylor...

    Authors: Wenhai Wang, Wei Jiang, Shengtao Zhu, Xiujing Sun, Peng Li, Kejia Liu, Henghui Liu, Junchao Gu and Shutian Zhang

    Citation: BMC Gastroenterology 2019 19:186

    Content type: Research article

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  20. Bile acid malabsorption (BAM) and bile acid-related diarrhea represent an under-recognized cause of chronic diarrhea mainly because of limited guidance on appropriate diagnostic and laboratory tests. We aimed ...

    Authors: Ivan Lyutakov, Francesco Ursini, Plamen Penchev, Giacomo Caio, Antonio Carroccio, Umberto Volta and Roberto De Giorgio

    Citation: BMC Gastroenterology 2019 19:185

    Content type: Research article

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  21. Current magnet-controlled capsule endoscopy (MCE) for the stomach is not yet satisfactory with respect to navigation control, especially in the gastric fundus and cardia. A newly developed MCE system conducted...

    Authors: Chun-sheng Cheng, Ting-ji Sun and Hou-de Zhang

    Citation: BMC Gastroenterology 2019 19:184

    Content type: Research article

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  22. Colorectal cancer (CRC) screening rates are low in the general population and among health care providers. The aim of this study was to evaluate the CRC screening practices of general surgeons who provide spec...

    Authors: Suleyman Utku Celik, Hasan Gorkem Cay, Ersin Bayrakdar, Aysima Ince, Esra Nur Ince, Yasemin Celik, Yunus Emre Yucel, Mehmet Ali Koc, Siyar Ersoz and Cihangir Akyol

    Citation: BMC Gastroenterology 2019 19:183

    Content type: Research article

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  23. Patients using opioids to treat chronic non-cancer pain often experience side effects that may affect health-related quality of life (HRQOL). These side effects include opioid-induced constipation (OIC), sedat...

    Authors: Michelle S. Keller, Alma Jusufagic and Brennan M. R. Spiegel

    Citation: BMC Gastroenterology 2019 19:182

    Content type: Research article

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  24. Pneumatic dilation (PD) is often billed as a “short term” treatment for achalasia but anecdotally can last years. This study sought to explore how long a single pneumatic dilation may induce symptom remission ...

    Authors: Abid T. Javed, Kevin Batte, Mohamed Khalaf, Mustafa Abdul-Hussein, Pooja S. Elias and Donald O. Castell

    Citation: BMC Gastroenterology 2019 19:181

    Content type: Research article

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  25. A validated histopathological tool to precisely evaluate bowel fibrosis in patients with Crohn’s disease is lacking. We attempted to establish a new index to quantify the severity of bowel fibrosis in patients...

    Authors: Xue-hua Li, Zhuang-nian Fang, Tian-ming Guan, Jin-jiang Lin, Can-hui Sun, Si-yun Huang, Ren Mao, Bao-lan Lu, Qing-hua Cao, Shi-ting Feng and Zi-ping Li

    Citation: BMC Gastroenterology 2019 19:180

    Content type: Research article

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  26. Studies indicate that gastric cancer (GC) incidence has decreased, whereas signet ring cell carcinoma (SRC) incidence has increased. However, recent trends in GC incidence are unclear. We used our hospital can...

    Authors: Hiroshi Ohyama, Dai Yoshimura, Yosuke Hirotsu, Kenji Amemiya, Hiroyuki Amano, Yuko Miura, Hiroshi Ashizawa, Keiko Nakagomi, Shinya Takaoka, Kenji Hosoda, Yoji Suzuki, Toshio Oyama, Masao Hada, Yuichiro Kojima, Hitoshi Mochizuki and Masao Omata

    Citation: BMC Gastroenterology 2019 19:178

    Content type: Research article

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  27. Choledocholithiasis is an endemic condition in the world. Although rare, foreign body migration with biliary complications needs to be considered in the differential diagnosis for patients presenting with typi...

    Authors: Min Yu, Bowen Huang, Ye Lin, Yuxue Nie, Zixuan Zhou, Shanshan Liu and Baohua Hou

    Citation: BMC Gastroenterology 2019 19:177

    Content type: Case report

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  28. Colonoscopy is associated with a risk of peritonitis in patients on peritoneal dialysis. However, no study has yet described the risk factors in play.

    Authors: Tae-Geun Gweon, Sung Hoon Jung, Sang Woo Kim, Kang-Moon Lee, Dae Young Cheung, Bo-In Lee and Hwang Choi

    Citation: BMC Gastroenterology 2019 19:175

    Content type: Research article

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  29. To compare the outcomes of submucosal tunneling endoscopic resection (STER) and submucosal excavation (ESE) for the treatment of submucosal tumors (SMTs) arising from the muscularis propria (MP) at the esophag...

    Authors: Hong-wei Xu, Qi Zhao, Shu-xia Yu, Ying Jiang, Jing-hua Hao and Bin Li

    Citation: BMC Gastroenterology 2019 19:174

    Content type: Research article

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  30. Molecular characteristics of CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) have been well documented in Western, but not in Chinese, populations.

    Authors: Jiang Liu, Li Tang, Jinhua Yi, Guimei Li, Youwang Lu, Yu Xu, Shuhua Zhao, Rui Mao, Xiaolu Li, Li Ren and Kunhua Wang

    Citation: BMC Gastroenterology 2019 19:173

    Content type: Research article

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  31. Hepatolithiasis, featuring high incidence, severe symptoms, and common recurrence, poses a heavy disease burden. Endoscopic management provides an opportunity to cure hepatolithiasis, but fails to properly res...

    Authors: Jianying Lou, Qida Hu, Tao Ma, Wei Chen, Ji Wang and Prasoon Pankaj

    Citation: BMC Gastroenterology 2019 19:172

    Content type: Technical advance

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  32. The extra-intestinal manifestation of tracheobronchitis is a rare complication of ulcerative colitis (UC). Here, we present a case of UC-related tracheobronchitis wherein the positive clinical effects of infli...

    Authors: Lisa Horgan, Siobhain Mulrennan, Lloyd D’Orsogna and Andrew McLean-Tooke

    Citation: BMC Gastroenterology 2019 19:171

    Content type: Case report

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  33. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) can induce a stronger regenerative ability than traditional 2-stage hepatectomy (TSH). ALPPS has become popular for achieving...

    Authors: Xukun Wu, Jiawei Rao, Xiaozhuan Zhou, Ronghai Deng and Yi Ma

    Citation: BMC Gastroenterology 2019 19:170

    Content type: Research article

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  34. Pruritus is a common symptom seen in patients with chronic liver disease. However, frequency and severity of pruritus in patients with chronic liver disease is unclear. We investigated frequency, severity and ...

    Authors: Hatsue Fujino, Mio Tanaka, Michio Imamura, Kei Morio, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Tomokazu Kawaoka, Shoichi Takahashi, Daiki Miki, Masataka Tsuge, Akira Hiramatsu, Hiroshi Aikata, C. Nelson Hayes and Kazuaki Chayama

    Citation: BMC Gastroenterology 2019 19:169

    Content type: Research article

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  35. The efficacy of some therapeutic methods (open surgical debridement (OSD), conservative treatment (CST) and minimally invasive drainage (MID)) for severe acute pancreatitis (SAP) and moderately severe acute pa...

    Authors: Kai Zhang, Xiaole Zhu, Chaoqun Hou, Chenyuan Shi, Yi Miao and Qiang Li

    Citation: BMC Gastroenterology 2019 19:168

    Content type: Research article

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  36. To investigate the von Willebrand factor to ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma (HCC) in cirrhosis.

    Authors: Hiroaki Takaya, Tadashi Namisaki, Mitsuteru Kitade, Kosuke Kaji, Keisuke Nakanishi, Yuki Tsuji, Naotaka Shimozato, Kei Moriya, Kenichiro Seki, Yasuhiko Sawada, Soichiro Saikawa, Shinya Sato, Hideto Kawaratani, Takemi Akahane, Ryuichi Noguchi, Masanori Matsumoto…

    Citation: BMC Gastroenterology 2019 19:167

    Content type: Research article

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  37. A nested qualitative interview study within the CONSTRUCT trial was conducted to explore experiences and perceptions of patients with acute severe ulcerative colitis following treatment with infliximab or cicl...

    Authors: Frances Rapport, Clare Clement, Anne C. Seagrove, Laith Alrubaiy, Hayley A. Hutchings and John G. Williams

    Citation: BMC Gastroenterology 2019 19:166

    Content type: Research article

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  38. Genetic factors increase the risk of irritable bowel syndrome (IBS). Analysis of single nucleotide polymorphisms (SNPs) has been used in IBS patients, but the findings are inconsistent. The goal of this review...

    Authors: Shiwei Zhu, Ben Wang, Qiong Jia and Liping Duan

    Citation: BMC Gastroenterology 2019 19:165

    Content type: Research article

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  39. Small nucleolar RNA host gene 6 (SNHG6) regulates diverse biological processes in cancers. Potential function of SNHG6 in human colon and rectal adenocarcinoma (CRC) was evaluated.

    Authors: Qianwen Shao, Jing Xu, Rong Deng, Wei Wei, Bing Zhou, Chao Yue, Miaoling Zhu and Haitao Zhu

    Citation: BMC Gastroenterology 2019 19:163

    Content type: Research article

    Published on:

  40. Plaque psoriasis and inflammatory bowel disease (IBD) are both chronic immune-mediated inflammatory diseases with an overlapping genetic profile and have been linked in epidemiological studies. Psoriasis and I...

    Authors: Matthew K. Smith, Jay Pai, Remo Panaccione, Paul Beck, Jose G. Ferraz and Humberto Jijon

    Citation: BMC Gastroenterology 2019 19:162

    Content type: Case report

    Published on:

  41. Extracorporeal liver support therapies (ELS) are technical options (for bridge-to-recovery as well as bridge-to-transplant) in patients with acute liver dysfunction (e.g. acute liver failure (ALF), acute-on ch...

    Authors: Thomas Wiesmann, Dominic Hoenl, Hinnerk Wulf and Marc Irqsusi

    Citation: BMC Gastroenterology 2019 19:160

    Content type: Research article

    Published on:

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