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  1. Content type: Research article

    A nested qualitative interview study within the CONSTRUCT trial was conducted to explore experiences and perceptions of patients with acute severe ulcerative colitis following treatment with infliximab or cicl...

    Authors: Frances Rapport, Clare Clement, Anne C. Seagrove, Laith Alrubaiy, Hayley A. Hutchings and John G. Williams

    Citation: BMC Gastroenterology 2019 19:166

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  2. Content type: Research article

    Genetic factors increase the risk of irritable bowel syndrome (IBS). Analysis of single nucleotide polymorphisms (SNPs) has been used in IBS patients, but the findings are inconsistent. The goal of this review...

    Authors: Shiwei Zhu, Ben Wang, Qiong Jia and Liping Duan

    Citation: BMC Gastroenterology 2019 19:165

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  4. Content type: Research article

    Small nucleolar RNA host gene 6 (SNHG6) regulates diverse biological processes in cancers. Potential function of SNHG6 in human colon and rectal adenocarcinoma (CRC) was evaluated.

    Authors: Qianwen Shao, Jing Xu, Rong Deng, Wei Wei, Bing Zhou, Chao Yue, Miaoling Zhu and Haitao Zhu

    Citation: BMC Gastroenterology 2019 19:163

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  5. Content type: Case report

    Plaque psoriasis and inflammatory bowel disease (IBD) are both chronic immune-mediated inflammatory diseases with an overlapping genetic profile and have been linked in epidemiological studies. Psoriasis and I...

    Authors: Matthew K. Smith, Jay Pai, Remo Panaccione, Paul Beck, Jose G. Ferraz and Humberto Jijon

    Citation: BMC Gastroenterology 2019 19:162

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  6. Content type: Research article

    The Fecal Occult Blood Test (FOBT) is one of the diagnostic modalities indicated for screening patients for Colorectal Cancer (CRC). Despite being approved only for screening for CRC, numerous studies in the p...

    Authors: Sarthak Soin, Olalekan Akanbi, Abdullah Ahmed, Yunha Kim, Sarbagya Pandit, Igor Wroblewski and Nasir Saleem

    Citation: BMC Gastroenterology 2019 19:161

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  7. Content type: Research article

    Extracorporeal liver support therapies (ELS) are technical options (for bridge-to-recovery as well as bridge-to-transplant) in patients with acute liver dysfunction (e.g. acute liver failure (ALF), acute-on ch...

    Authors: Thomas Wiesmann, Dominic Hoenl, Hinnerk Wulf and Marc Irqsusi

    Citation: BMC Gastroenterology 2019 19:160

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  9. Content type: Research article

    The pathways and mechanism by which associations between the gut microbiome and the brain, termed the microbiome-gut-brain axis (MGBA), are manifest but remain to be fully elucidated. This study aims to use bi...

    Authors: Sa’ed H. Zyoud, Simon Smale, W. Stephen Waring, Waleed M. Sweileh and Samah W. Al-Jabi

    Citation: BMC Gastroenterology 2019 19:158

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  10. Content type: Research article

    An intestinal stoma, though a life-saving procedure on the care of many gastrointestinal conditions, carries significant number of complications. This study describes the common indications, complications, and...

    Authors: Alicia Massenga, Alfred Chibwae, Aloyce A. Nuri, Merchades Bugimbi, Yasin K. Munisi, Ramadhani Mfinanga and Phillipo L. Chalya

    Citation: BMC Gastroenterology 2019 19:157

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  11. Content type: Case report

    Haemolytic uraemic syndrome is a rarely seen in adults often leading to critical illness. This case highlights how difficult it can be to establish a diagnosis and treat when a patient presents with bloody dia...

    Authors: Shiva Thambiah Radhakrishnan, Aruchuna Ruban, Aarthy Kanmany Uthayakumar, Patrizia Cohen, Jeremy Levy and Julian Teare

    Citation: BMC Gastroenterology 2019 19:156

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  12. Content type: Case report

    Intramural esophageal bronchogenic cyst is very rare. Surgical removal of the cysts is advised even the patients are asymptomatic, since the cyst can lead to complications, and there is a risk of malignant tra...

    Authors: Xun Yang, Ye Zong, Hai-Ying Zhao, Yong-Dong Wu and Ming Ji

    Citation: BMC Gastroenterology 2019 19:155

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  13. Content type: Case report

    Systemic lupus erythematosus is an autoimmune disease which can affect multiple organs, resulting in significant mortality and morbidity. Lupus enteritis is one of the rare complications of SLE, defined as vas...

    Authors: Xiu-Li Zhu, Xue-Mei Xu, Si Chen, Qiao-Min Wang and Kai-Guang Zhang

    Citation: BMC Gastroenterology 2019 19:154

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  14. Content type: Research article

    Primary sclerosing cholangitis is a chronic cholestatic liver disease. The pathomechanism is still not fully understood, but there is evidence that immune-mediated processes may contribute to disease progression.

    Authors: Theresa Hippchen, Peter Sauer, Benjamin Göppert, Peter Schirmacher, Daniel Nils Gotthardt, Karl-Heinz Weiss, Wolfgang Stremmel and Christian Rupp

    Citation: BMC Gastroenterology 2019 19:153

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  16. Content type: Case report

    With the development and application of endoscopic technology, most pedunculated polyps can be absolutely resected with a complete specimen by hot snare polypectomy (HSP). Brunner’s gland hamartoma (BGH) is a ...

    Authors: Lizhi Yi, Zhengyu Cheng, Huarong Qiu, Jianjun Yang, Tao Wang and Ke Liu

    Citation: BMC Gastroenterology 2019 19:151

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  17. Content type: Research article

    Alcoholic liver disease (ALD) is the leading cause of liver transplantation (LT). The magnitude and risk factors of post-LT alcohol relapse are not well described. We conducted a meta-analysis to evaluate alco...

    Authors: Lancharat Chuncharunee, Noriyo Yamashiki, Ammarin Thakkinstian and Abhasnee Sobhonslidsuk

    Citation: BMC Gastroenterology 2019 19:150

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  18. Content type: Research article

    To evaluate the role of colonoscopy in infants and young children and clarify the distribution of colonoscopy-requiring diseases in this age group.

    Authors: Ryusuke Nambu, Shin-ichiro Hagiwara, Fumihiko Kakuta, Tomoko Hara, Hirotaka Shimizu, Daiki Abukawa, Itaru Iwama, Seiichi Kagimoto and Katsuhiro Arai

    Citation: BMC Gastroenterology 2019 19:149

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  19. Content type: Research article

    Caspase-1 is an evolutionarily conserved enzyme that proteolytically cleaves the precursors of the inflammatory cytokines interleukin 1β and interleukin 18. However, the role of caspase-1 in determining the se...

    Authors: Xiangying Zhang, Peiling Dong, Lin Xu, Yuan Tian, Huayin Sun, Hongbo Shi, Zhongping Duan, Liyan Chen and Feng Ren

    Citation: BMC Gastroenterology 2019 19:148

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  20. Content type: Research article

    Prior hepatitis B virus infection (PBI) may increase the risk of developing hepatocellular carcinoma (HCC), but the impact of PBI on clinical outcomes following treatment for HCC remains unknown. The aim of th...

    Authors: Yutaka Midorikawa, Tadatoshi Takayama, Hisashi Nakayama, Tokio Higaki, Masamichi Moriguchi, Kyoji Moriya, Tatsuo Kanda, Shunichi Matsuoka and Mitsuhiko Moriyama

    Citation: BMC Gastroenterology 2019 19:147

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  21. Content type: Research article

    Microvessel density (MVD), as a derived marker for angiogenesis, has been associated with poor outcome in several types of cancer. This study aimed to evaluate the prognostic value of MVD in stage II and III c...

    Authors: Sjoerd H. den Uil, Evert van den Broek, Veerle M. H. Coupé, Thomas T. Vellinga, Pien M. Delis-van Diemen, Herman Bril, Eric J. Th. Belt, Onno Kranenburg, Hein B. A. C. Stockmann, Jeroen A. M. Belien, Gerrit A. Meijer and Remond J. A. Fijneman

    Citation: BMC Gastroenterology 2019 19:146

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  22. Content type: Research article

    This study aimed to understand the disease characteristics and treatment outcomes of Crohn’s disease (CD) in a real-world setting in China.

    Authors: Yue Li, Baili Chen, Xiang Gao, Naizhong Hu, Meifang Huang, Zhihua Ran, Zhanju Liu, Jie Zhong, Duowu Zou, Xiaoping Wu, Jianlin Ren, Jianqiu Sheng, Ping Zheng, Huahong Wang, Minhu Chen, Junrong Chen…

    Citation: BMC Gastroenterology 2019 19:145

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  23. Content type: Case report

    Splenic nodules are uncommon entities that occur rarely in the general population. Although an infectious etiology (primarily bacteria, followed by mycobacteria) is usually found, noninfectious diseases, inclu...

    Authors: D. F. Bavaro, G. Ingravallo, F. Signorile, F. Fortarezza, F. Di Gennaro, G. Angarano and A. Saracino

    Citation: BMC Gastroenterology 2019 19:144

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  24. Content type: Research article

    Reports showed adenoma miss rates (AMRs) of 22.5–27% in the right colon and 23.4–33.3% in the proximal colon. Missed lesions could contribute to postcolonoscopy cancers. Water exchange (WE) with near-complete ...

    Authors: Chi-Liang Cheng, Yen-Lin Kuo, Yu-Hsi Hsieh, Jui-Hsiang Tang and Felix W. Leung

    Citation: BMC Gastroenterology 2019 19:143

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  25. Content type: Case report

    Paragangliomas, also known as chemodectomas, are rare tumors arise from chemoreceptor tissue, and most commonly locate at the bifurcation of the common carotid, the jugular foramen, aortic arch, and retroperit...

    Authors: Zhao-Ru Dong, Yan-Ni Xia, Yue-Yi Zhao, Rui Wu, Kai-Xuan Liu, Kai Shi, Lun-Jie Yan, Cheng-Yu Yao, Yu-Chuan Yan and Tao Li

    Citation: BMC Gastroenterology 2019 19:142

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    The Correction to this article has been published in BMC Gastroenterology 2019 19:152

  26. Content type: Case report

    Abdominal compartment syndrome (ACS) is associated with mortality in patients with critical illness such as severe acute pancreatitis, but it remains unclear whether decompressive laparotomy for ACS can improv...

    Authors: Shinya Ikeda, Takuma Kagami, Shinya Tani, Takahiro Uotani, Mihoko Yamade, Yasushi Hamaya, Yoshifumi Morita, Takanori Sakaguchi, Satoshi Osawa and Ken Sugimoto

    Citation: BMC Gastroenterology 2019 19:141

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  27. Content type: Research article

    Individuals can be infected with multiple strains of Helicobacter pylori. However, the differences among co-infecting strains have not been well analyzed yet. This study aimed to investigate whether the virulence...

    Authors: Ji Won Seo, Jae Yong Park, Tae-Seop Shin and Jae Gyu Kim

    Citation: BMC Gastroenterology 2019 19:140

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  28. Content type: Research article

    Endoscopic transpapillary cannulation of the gallbladder is useful but challenging. This study aimed to investigate cystic duct anatomy patterns, which may guide cystic duct cannulation.

    Authors: Jun Cao, Xiwei Ding, Han Wu, Yonghua Shen, Ruhua Zheng, Chunyan Peng, Lei Wang and Xiaoping Zou

    Citation: BMC Gastroenterology 2019 19:139

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  30. Content type: Case report

    The increasing life expectancy of individuals with Cystic Fibrosis (CF) is likely to be associated with new age-related challenges, colorectal cancer (CRC) most notably; recent consensus recommendations for CRC s...

    Authors: James M. Abraham, Kathleen Mahan, Tetyana Mettler, Jordan M. Dunitz and Alexander Khoruts

    Citation: BMC Gastroenterology 2019 19:137

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  31. Content type: Research article

    Risk stratification for patients with nonvariceal upper gastrointestinal (NVUGI) bleeding is crucial for successful prognosis and treatment. Recently, the AIMS65 score has been used to predict mortality risk a...

    Authors: Min Seong Kim, Jeongmin Choi and Won Chang Shin

    Citation: BMC Gastroenterology 2019 19:136

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  32. Content type: Research article

    This study aims to evaluate the efficacy and safety of detecting and removing residual common bile duct stones (CBDS) using direct peroralcholangioscopy (DPOC) after performing endoscopic retrograde cholangiop...

    Authors: Jun-Jie Yang, Xiong-Chang Liu, Xiao-Qin Chen, Qi-Yong Zhang and Tian-Rang Liu

    Citation: BMC Gastroenterology 2019 19:135

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  33. Content type: Research article

    In cirrhosis upper-gastrointestinal-endoscopy (UGIE) identifies oesophageal varices (OV). UGIE is unavailable in most resource-limited settings. Therefore, we assessed prediction of presence of OV using hemato...

    Authors: K. Perera, S. K. Kodisinghe, D. S. Ediriweera, D. Moratuwagama, S. Williams, A. Pathmeswaran, M. A. Niriella and H. J. de Silva

    Citation: BMC Gastroenterology 2019 19:134

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  34. Content type: Research article

    The aim of the present study was to evaluate the effects of curcumin supplementation on inflammatory indices, and hepatic features in patients with non-alcoholic fatty liver disease (NAFLD).

    Authors: Saeede Saadati, Amir Sadeghi, Asieh Mansour, Zahra Yari, Hossein Poustchi, Mehdi Hedayati, Behzad Hatami and Azita Hekmatdoost

    Citation: BMC Gastroenterology 2019 19:133

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  35. Content type: Research article

    Eradicating Helicobacter pylori infection is clinically challenging, notably in cases with penicillin allergy. Cephalosporin could be used in lieu of amoxicillin to eradicate Helicobacter pylori. The current work...

    Authors: Zhiqiang Song, Wei Fu and Liya Zhou

    Citation: BMC Gastroenterology 2019 19:132

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  36. Content type: Research article

    Our study aimed to determine the effect of probiotic consumption containing six viable microorganisms of 30 × 1010 cfu Lactobacillus and Bifidobacteria strains for six months on clinical outcomes and inflammatory...

    Authors: Liyana Zaharuddin, Norfilza Mohd Mokhtar, Khairul Najmi Muhammad Nawawi and Raja Affendi Raja Ali

    Citation: BMC Gastroenterology 2019 19:131

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  37. Content type: Research article

    Hepatocellular carcinoma (HCC) is a kind of malignancies to impact human health. It has been reported that aberrant toll-like receptor (TLR) signaling may contribute to the development and progression of HCC, ...

    Authors: Liyu Shi, Xiaoqiu Zheng, Yuzhuo Fan, Xiaolan Yang, Aimei Li and Jun Qian

    Citation: BMC Gastroenterology 2019 19:130

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  38. Content type: Research article

    Imaging is an essential tool in the management of patients with Colorectal cancer (CRC) by helping evaluate number and sites of metastases, determine resectability, assess response to treatment, detect drug to...

    Authors: Vincenza Granata, Roberta Fusco, Elisabetta de Lutio di Castelguidone, Antonio Avallone, Raffaele Palaia, Paolo Delrio, Fabiana Tatangelo, Gerardo Botti, Roberto Grassi, Francesco Izzo and Antonella Petrillo

    Citation: BMC Gastroenterology 2019 19:129

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  40. Content type: Research article

    To provide criteria for the differential diagnosis of serous cystic neoplasms (SCNs) and mucinous cystic neoplasms (MCNs) by analyzing the imaging features of these two neoplasms by endoscopic ultrasound (EUS).

    Authors: Lisen Zhong, Ningli Chai, Enqiang Linghu, Huikai Li, Jing Yang and Ping Tang

    Citation: BMC Gastroenterology 2019 19:127

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  41. Content type: Research article

    This study aimed to evaluate the association between serum vitamin D levels and nonalcoholic fatty liver disease (NAFLD) parameters, such as metabolic syndrome (MS), inflammatory cytokines (tumor necrosis fact...

    Authors: Li-Wei Chen, Cheng-Hung Chien, Sheng-Fong Kuo, Chia-Ying Yu, Chih-Lang Lin and Rong-Nan Chien

    Citation: BMC Gastroenterology 2019 19:126

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  42. Content type: Research article

    General overnutrition is one of the key factors involved in the development of nonalcoholic fatty liver disease (NAFLD) as the most common liver disease occur by two steps of liver injury ranges from steatosis...

    Authors: Feryal Savari, Seyyed Ali Mard, Mohammad Badavi, Anahita Rezaie and Mohammad Kazem Gharib-Naseri

    Citation: BMC Gastroenterology 2019 19:125

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  43. Content type: Research article

    Bone mesenchymal stromal cells (BMSC) showed protective potential against intestinal ischemia. Oxygenase-1(HO-1) could alleviate oxidative stress. In the present study, we constructed HO-1-expressing BMSC and ...

    Authors: Xue-Tao Yan, Xiao-Li Cheng, Xiang-Hu He, Wen-Zhong Zheng, Yuan Xiao-Fang and Chen Hu

    Citation: BMC Gastroenterology 2019 19:124

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  44. Content type: Case report

    Cystic fibrosis (CF) is a genetic disorder of the epithelial CFTR apical chloride channel resulting in multi-organ manifestations, including pancreatic exocrine secretion. In the pancreas, CFTR abnormality res...

    Authors: J. Dixon Johns and Steven M. Rowe

    Citation: BMC Gastroenterology 2019 19:123

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  45. Content type: Research article

    The identification of patients with advanced liver fibrosis secondary to non-alcoholic fatty liver disease (NAFLD) remains challenging. Using non-invasive liver fibrosis tests (NILT) in primary care may permit...

    Authors: Ankur Srivastava, Simcha Jong, Anna Gola, Ruth Gailer, Sarah Morgan, Karen Sennett, Sudeep Tanwar, Elena Pizzo, James O’Beirne, Emmanuel Tsochatzis, Julie Parkes and William Rosenberg

    Citation: BMC Gastroenterology 2019 19:122

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  46. Content type: Research article

    Endoscopic mucosal resection (EMR) in piecemeal technique is the treatment standard for larger flat or sessile colorectal lesions. The method is burdened by a high recurrence rate mostly presenting as difficul...

    Authors: Annabell von Helden, Ralf Hildenbrand, Bernd Sido and Franz Ludwig Dumoulin

    Citation: BMC Gastroenterology 2019 19:121

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  48. Content type: Research article

    The effectiveness in surveillance colonoscopy largely depends on the quality of bowel preparation. We aimed to investigate the quality of bowel preparation segmentally and its effect on Adenoma Detection Rate ...

    Authors: Rui Guo, Yong-Jun Wang, Mo Liu, Jun Ge, Ling-Ye Zhang, Ling Ma, Wen-Yu Huang and Hui-Hong Zhai

    Citation: BMC Gastroenterology 2019 19:119

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  49. Content type: Research article

    Multiple organ failure (MOF) is a serious complication of moderately severe (MASP) and severe acute pancreatitis (SAP). This study aimed to develop and assess three machine-learning models to predict MOF.

    Authors: Qiu Qiu, Yong-jian Nian, Yan Guo, Liang Tang, Nan Lu, Liang-zhi Wen, Bin Wang, Dong-feng Chen and Kai-jun Liu

    Citation: BMC Gastroenterology 2019 19:118

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