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  1. Perforation and obstruction in colorectal cancer are poor prognostic factors. We aimed to evaluate the oncological outcomes of patients with colon cancer presenting with perforation or obstruction.

    Authors: Kwan Mo Yang, Min-Jae Jeong, Kwang Hyun Yoon, Yun Tae Jung and Jae Young Kwak
    Citation: BMC Gastroenterology 2022 22:247
  2. Calcification of abdominal lymph node is a common clinical phenomenon, but it is extremely rare to cause serious adverse clinical outcomes. In the present case, the ruptured hemorrhage of the oesophagogastric ...

    Authors: Shuming Liu, Xingwu Xie, Xianzhi Tang, Huan He, Huiyuan Guan and Guangbin Chen
    Citation: BMC Gastroenterology 2022 22:245
  3. Increased pancreatic cancer incidence has been observed among younger than in older adults. This pilot study aimed to determine the feasibility of a large study that would compare the age at diagnosis of pancr...

    Authors: Ro-Ting Lin, Pei-Lung Chen, Chi-Ying Yang, Chun-Chieh Yeh, Chun-Che Lin, Wen-Hsin Huang, An-Ko Chung and Jaw-Town Lin
    Citation: BMC Gastroenterology 2022 22:243
  4. Fatty liver is frequently found in a general population, and it is critical to detect advanced fibrosis. FIB-4 index is considered a useful marker for evaluating liver fibrosis but the distribution of FIB-4 in...

    Authors: Aya Sugiyama, Akemi Kurisu, Bunthen E, Serge Ouoba, Ko Ko, Anvarjon Rakhimov, Tomoyuki Akita, Takayuki Harakawa, Toru Sako, Makoto Koshiyama, Takashi Kumada and Junko Tanaka
    Citation: BMC Gastroenterology 2022 22:241
  5. Urinary and faecal metabolic profiling have been extensively studied in gastrointestinal diseases as potential diagnostic markers, and to enhance our understanding of the intestinal microbiome in the pathogene...

    Authors: Sam T. R. Powles, Kate I. Gallagher, Leo W. L. Chong, James L. Alexander, Benjamin H. Mullish, Lucy C. Hicks, Julie A. K. McDonald, Julian R. Marchesi, Horace R. T. Williams and Timothy R. Orchard
    Citation: BMC Gastroenterology 2022 22:240
  6. Low anterior resection syndrome (LARS) is the most common complication after rectal cancer resection. We aimed to identify LARS' predictive factors and construct and evaluate a predictive model for LARS.

    Authors: Masakatsu Paku, Norikatsu Miyoshi, Shiki Fujino, Tsuyoshi Hata, Takayuki Ogino, Hidekazu Takahashi, Mamoru Uemura, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki and Hidetoshi Eguchi
    Citation: BMC Gastroenterology 2022 22:239
  7. Studies have confirmed the prognostic value of the expression status of human epidermal growth factor receptor 2 (HER2) in advanced gastric cancer. However, its role in early gastric cancer (EGC) remains large...

    Authors: Hui Li, Longsong Li, Nan Zhang, Zixin Wang, Ning Xu, Enqiang Linghu and Ningli Chai
    Citation: BMC Gastroenterology 2022 22:238
  8. Endocytoscopy (ECS) aids early gastric cancer (EGC) diagnosis by visualization of cells. However, it is difficult for non-experts to accurately diagnose EGC using ECS. In this study, we developed and evaluated...

    Authors: Hiroto Noda, Mitsuru Kaise, Kazutoshi Higuchi, Eriko Koizumi, Keiichiro Yoshikata, Tsugumi Habu, Kumiko Kirita, Takeshi Onda, Jun Omori, Teppei Akimoto, Osamu Goto, Katsuhiko Iwakiri and Tomohiro Tada
    Citation: BMC Gastroenterology 2022 22:237
  9. Capsule endoscopy (CE) provides a novel approach to evaluate obscure gastrointestinal bleeding. Yet CE is not routinely utilized in the inpatient setting for a variety of reasons. We sought to identify factors...

    Authors: Irving Levine, Soonwook Hong, Dimpal Bhakta, Matthew B. McNeill, Seth A. Gross and Melissa Latorre
    Citation: BMC Gastroenterology 2022 22:236
  10. Authors: Chang Hong, Chengkai Wu, Pengcheng Ma, Hao Cui, Liya Chen, Ruining Li, Qimei Li, Lin Zeng, Shengwu Liao, Lushan Xiao, Li Liu and Wenyuan Li
    Citation: BMC Gastroenterology 2022 22:235

    The original article was published in BMC Gastroenterology 2022 22:185

  11. Aberrations in cyclooxygenase and lipoxygenase (LOX) pathways in non-neoplastic, normal appearing mucosa from patients with colorectal neoplasia (CRN), could hypothetically qualify as predisposing CRN-markers.

    Authors: Ulrike Ries Feddersen, Sebastian Kjærgaard Hendel, Mark Alexander Berner-Hansen, Thomas Andrew Jepps, Mark Berner-Hansen and Niels Bindslev
    Citation: BMC Gastroenterology 2022 22:234
  12. Adipokines such as leptin, visfatin and chemerin play a pivotal role not only in the pathogenesis of excessive weight gain but also impact on hepatic metabolism. However, alterations in the production of these...

    Authors: I. Kasacka, Ż. Piotrowska, N. Domian, A. Lewandowska and M. Acewicz
    Citation: BMC Gastroenterology 2022 22:233
  13. The detection rate of methylated Septin9 (mSEPT9) in colorectal cancer (CRC) is varied greatly across the studies. This study aimed to evaluate the diagnostic ability of mSEPT9 in CRC, and compare the diagnost...

    Authors: Dong-cheng Lu, Qi-fang Zhang, Li Li, Xian-ke Luo, Bin Liang, Yi-han Lu, Bang-li Hu and Hai-xing Jiang
    Citation: BMC Gastroenterology 2022 22:232
  14. Acute kidney injury (AKI) is a common and life-threatening complication of liver failure. The purpose of this study is to construct a nomogram and online calculator to predict the development of hospital-acqui...

    Authors: Yue Huang, Junjun Cai, Fushuang Ha, Beichen Guo, Shaojie Xin, Zhongping Duan and Tao Han
    Citation: BMC Gastroenterology 2022 22:231
  15. Mucosal healing (MH) has become the treatment goal of patients with Crohn’s disease (CD). This study aims to develop a noninvasive and reliable clinical tool for individual evaluation of mucosal healing in pat...

    Authors: Nana Tang, Han Chen, Ruidong Chen, Wen Tang and Hongjie Zhang
    Citation: BMC Gastroenterology 2022 22:229
  16. Entecavir (ETV) can suppress chronic hepatitis B (CHB) virus replication as a standard of treatment drugs. For the treatment of CHB, affordable generic drugs may be more widely used in developing and undevelop...

    Authors: Po-Ke Hsu, Pei-Yuan Su and Chia-Lin Wu
    Citation: BMC Gastroenterology 2022 22:228
  17. Patients with acid sphingomyelinase deficiency (ASMD) may be referred to a hepatologist for liver manifestations. This study summarized the liver manifestations of patients with ASMD in the early disease course.

    Authors: Neng-Li Wang, Jing Lin, Lian Chen, Yi Lu, Xin-Bao Xie, Kuerbanjiang Abuduxikuer and Jian-She Wang
    Citation: BMC Gastroenterology 2022 22:227
  18. Primary duodenal cancer (PDC) is rare, especially signet-ring cell carcinoma (SRCC) of the duodenal bulb, and it is commonly misdiagnosed as an ulceration. Here, we report a rare case of SRCC of the duodenal b...

    Authors: Nan Ye, Xiaoxiao Bao, Xiaokang Zhao and Bin Wang
    Citation: BMC Gastroenterology 2022 22:226
  19. Low-dose aspirin and clopidogrel have demonstrated potential chemoprevention for colorectal cancer (CRC). Proton-pump inhibitors (PPI) are commonly prescribed with anticoagulation drugs, but the relationship b...

    Authors: Pei-Huan Ho, Hung-Chun Hsiao, Chun-Wei Chen, Hui-Ming Chen, Siew-Na Lim, Chau-Ting Yeh, Chia-Jung Kuo and Wey-Ran Lin
    Citation: BMC Gastroenterology 2022 22:225
  20. Pure laparoscopic liver resection (LLR) of segment 8 (S8) is still rarely performed due to the lack of an appropriate surgical approach. This article discusses the technical tips and operation methods for LLR ...

    Authors: Nan You, Ke Wu, Jing Li and Lu Zheng
    Citation: BMC Gastroenterology 2022 22:224
  21. The lesions of certain diseases are widely distributed in both stomach and small intestine, while the step-by-step strategy of gastroscopy followed by enteroscopy can be burdensome and costly. We aimed to dete...

    Authors: Ya-Wei Liu, Yuan-Chen Wang, Jia-Hui Zhu, Xi Jiang, Wei Zhou, Jie Zhang, Zhuan Liao and En-Qiang Linghu
    Citation: BMC Gastroenterology 2022 22:222
  22. Small intestinal stricture is a major cause for surgery in Crohn’s disease (CD). Endoscopic balloon dilation (EBD) is performed for small intestinal strictures to avoid surgery, often repeatedly. However, fact...

    Authors: Shuji Hibiya, Kazuo Ohtsuka, Kento Takenaka, Ami Kawamoto, Yusuke Matsuyama, Yumi Udagawa, Maiko Motobayashi, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Ryuichi Okamoto and Mamoru Watanabe
    Citation: BMC Gastroenterology 2022 22:218
  23. Group A rotavirus (RVA) remains the main causative agent of acute diarrhea among children under five years in countries that have not yet introduced the RVA vaccine worldwide. Long-term and continuous monitori...

    Authors: Lijuan Lu, Huaqing Zhong, Ran Jia, Liyun Su, Menghua Xu, Lingfeng Cao, Pengcheng Liu, Yuanyun Ao, Niuniu Dong and Jin Xu
    Citation: BMC Gastroenterology 2022 22:217
  24. Cholecystectomy is performed for most gallbladder polyps (GPs). However, cholecystectomy results concerning complications in some patients. For benign GPs, adoption of gallbladder-preserving surgery is worth t...

    Authors: Xiao-Jian He, Zhi-Ping Chen, Xiang-Peng Zeng, Chuan-Shen Jiang, Gang Liu, Dong-Liang Li, Da-Zhou Li and Wen Wang
    Citation: BMC Gastroenterology 2022 22:216
  25. The value of CT (computed tomography) sinography in evaluating abdominal wall sinus tracts is currently unclear. The present study aims to investigate the accuracy of CT sinography in diagnosing the extent of ...

    Authors: Xuechao Du, Yuchang Yan, Pengtao Sun, Shuo Yang, Zhenyu Pan, Sujun Liu and Tao Jiang
    Citation: BMC Gastroenterology 2022 22:214
  26. Risk stratification to identify patients with high risk of variceal rebleeding is particularly important in patients with decompensated cirrhosis. In clinical practice, eliminating gastroesphageal varices thor...

    Authors: Huiwen Guo, Ming Zhang, Na Zhang, Xiaochun Yin, Yang Cheng, Lihong Gu, Xixuan Wang, Jiangqiang Xiao, Yi Wang, Xiaoping Zou, Yuzheng Zhuge and Feng Zhang
    Citation: BMC Gastroenterology 2022 22:213
  27. This study aimed to determine the prognostic value of the sarcopenia on the progression free survival (PFS) and overall survival (OS) of esophageal squamous cell cancer (ESCC) patients who received radiotherap...

    Authors: Junchao Qian, Youjiao Si, Ke Zhou, Yu Tian, Qisen Guo, Kaikai Zhao and Jinming Yu
    Citation: BMC Gastroenterology 2022 22:211
  28. It is estimated that approximately 50% of patients with hepatitis C virus (HCV) infection in Japan are currently over 75 years old. However, patients aged ≥ 75 years are typically underrepresented in clinical ...

    Authors: Yuri Komaki, Yoshinori Ozono, Kenichi Nakamura, Hisayoshi Iwakiri, Satoru Hasuike, Mitsue Sueta, Tadashi Miike, Shojiro Yamamoto, Hirofumi Uto, Kazunori Kusumoto, Toshimasa Ochiai, Junya Kato, Naoto Komada, Kazuo Kuroki, Toshiharu Eto, Masafumi Shigehira…
    Citation: BMC Gastroenterology 2022 22:210
  29. Eosinophilic enteritis is a chronic inflammatory disorder of the intestinal tract that is characterized by eosinophil infiltration. Cytomegalovirus (CMV), a common virus, has a broad infectivity range. CMV is ...

    Authors: Yuichi Yamaga, Masahiro Mizuno, Shunji Okae, Mikako Nio-Tamaoki, Kenji Masuo, Yoko Mashimo-Matsuo, Junya Tanaka and Motoshige Nabeshima
    Citation: BMC Gastroenterology 2022 22:209
  30. Authors: Ahmed B. Bayoumy, Elsa L. S. A. van Liere, Melek Simsek, Ben Warner, Aathavan Loganayagam, Jeremy D. Sanderson, Simon Anderson, Jonathan Nolan, Nanne K. de Boer, Chris J. J. Mulder and Azhar Ansari
    Citation: BMC Gastroenterology 2022 22:208

    The original article was published in BMC Gastroenterology 2020 20:296

  31. Colorectal cancer (CRC) is the third most common of cancer-related deaths. Nucleolar protein 14 (NOP14) is known to play different roles in diverse types of cancers. However, little is known about its roles in...

    Authors: Caijie Lu, Weihua Liao, Yiwen Huang, Yaoxing Huang and Yuqi Luo
    Citation: BMC Gastroenterology 2022 22:207
  32. Authors: Jun Omori, Osamu Goto, Tsugumi Habu, Yumiko Ishikawa, Kumiko Kirita, Eriko Koizumi, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Teppei Akimoto, Naohiko Akimoto, Norio Itokawa, Mitsuru Kaise and Katsuhiko Iwakiri
    Citation: BMC Gastroenterology 2022 22:206

    The original article was published in BMC Gastroenterology 2022 22:139

  33. The purpose of this study was to investigate the short-term outcomes and prognosis of elderly and very elderly colorectal cancer (CRC) patients after primary CRC surgery using propensity score matching (PSM).

    Authors: Yu-Xi Cheng, Xiao-Yu Liu, Bing Kang, Wei Tao, Zheng-Qiang Wei and Dong Peng
    Citation: BMC Gastroenterology 2022 22:205
  34. Intermittent fasting (IF) during the month of Ramadan is part of the religious rituals of Muslims. The effect of intermittent fasting on disease activity in inflammatory bowel diseases (IBD) is still unknown. ...

    Authors: Mohamed Negm, Ahmed Bahaa, Ahmed Farrag, Rania M. Lithy, Hedy A. Badary, Mahmoud Essam, Shimaa Kamel, Mohamed Sakr, Waleed Abd El Aaty, Mostafa Shamkh, Ahmed Basiony, Ibrahim Dawoud and Hany Shehab
    Citation: BMC Gastroenterology 2022 22:203
  35. Alpha-fetoprotein (AFP) is a biomarker used in clinical management of hepatocellular carcinoma (HCC), however, approximately 40% of HCC patients do not present with elevated serum AFP levels. This study aimed ...

    Authors: Xiaowei Chi, Liejun Jiang, Yulin Yuan, Xinyan Huang, Xuemei Yang, Steven Hochwald, Jie Liu and Huayi Huang
    Citation: BMC Gastroenterology 2022 22:202
  36. Colorectal cancer is the third most common cancer in France and by the time of the diagnosis, 15–25% of patients will suffer from synchronous liver metastases. Surgery associated to neoadjuvant treatment can c...

    Authors: Elias Karam, Petru Bucur, Camille Gil, Remy Sindayigaya, Nicolas Tabchouri, Louise Barbier, Urs Pabst-Giger, Pascal Bourlier, Thierry Lecomte, Driffa Moussata, Sophie Chapet, Gilles Calais, Mehdi Ouaissi and Ephrem Salamé
    Citation: BMC Gastroenterology 2022 22:201
  37. Recent studies have shown that functional mitochondria are essential for cancer cells. Nuclear respiratory factor 1 (NRF1) is a transcription factor that activates mitochondrial biogenesis and the expression o...

    Authors: Dan Wang, Baolan Wan, Xiaojing Zhang, Pingping Sun, Shu Lu, Chenxu Liu and Li Zhu
    Citation: BMC Gastroenterology 2022 22:198
  38. Optimal concentration of ustekinumab (UST) predicting endoscopic remission has not been fully investigated in Crohn’s disease (CD). We aimed to identify the optimal UST trough levels predicting clinical, labor...

    Authors: Hisashi Hirayama, Yasuhiro Morita, Takayuki Imai, Kenichiro Takahashi, Atsushi Yoshida, Shigeki Bamba, Osamu Inatomi and Akira Andoh
    Citation: BMC Gastroenterology 2022 22:195

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