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  1. In contrast to adults, for whom guidelines on the cholelithiasis treatment exist, there is no consistent treatment of pediatric patients with cholelithiasis throughout national and international departments, m...

    Authors: Sonja Diez, Hanna Müller, Christel Weiss, Vera Schellerer and Manuel Besendörfer

    Citation: BMC Gastroenterology 2021 21:186

    Content type: Research

    Published on:

  2. Since December 2019, China has experienced a public health emergency from the coronavirus disease, which has become a pandemic and is impacting the care of cancer patients worldwide. This study evaluated the i...

    Authors: Yun Xu, Zong-Hao Huang, Charlie Zhi-Lin Zheng, Cong Li, Yu-Qin Zhang, Tian-An Guo, Fang-Qi Liu and Ye Xu

    Citation: BMC Gastroenterology 2021 21:185

    Content type: Research article

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  3. TAS-102 plus bevacizumab is an anticipated combination regimen for patients who have metastatic colorectal cancer. However, evidence supporting its use for this indication is limited. We compared the cost-effe...

    Authors: Kiyoaki Sugiura, Yuki Seo, Takayuki Takahashi, Hideyuki Tokura, Yasuhiro Ito, Motomu Tanaka, Norihiro Kishida, Yusuke Nishi, Yoshihiko Onishi and Hikaru Aoki

    Citation: BMC Gastroenterology 2021 21:184

    Content type: Research

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  4. Portal hepatic schwannoma is a rare benign tumor and difficult to diagnose preoperatively because of its rarity and imaging manifestations that mimic malignancy. We present a case of portal hepatic schwannoma ...

    Authors: Maki Amano, Yasuo Amano, Ryo Takagi, Xiaoyan Tang, Yuko Omori and Masahiro Okada

    Citation: BMC Gastroenterology 2021 21:183

    Content type: Case report

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  5. Transarterial chemoembolization (TACE) and radiofrequency ablation (RFA) are effective treatment methods for unresectable hepatocellular carcinoma (HCC). However, there is still a lack of clinical research on ...

    Authors: Liangliang Yan, Yanqiao Ren, Kun Qian, Xuefeng Kan, Hongsen Zhang, Lei Chen, Bin Liang and Chuansheng Zheng

    Citation: BMC Gastroenterology 2021 21:182

    Content type: Research

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  6. In general, all virulence factors of Helicobacter pylori (H. pylori) are involved in its infections. However, recent studies have shown that the homB gene is one of the virulence genes that affects the severity o...

    Authors: Masoud Keikha and Mohsen Karbalaei

    Citation: BMC Gastroenterology 2021 21:181

    Content type: Research

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  7. Non-alcoholic fatty liver disease (NAFLD) affects 20–30% of the general adult population. NAFLD patients with type 2 diabetes mellitus (T2DM) are at an increased risk of advanced fibrosis, which puts them at r...

    Authors: Patrik Nasr, Fredrik Iredahl, Nils Dahlström, Karin Rådholm, Pontus Henriksson, Gunnar Cedersund, Olof Dahlqvist Leinhard, Tino Ebbers, Joakim Alfredsson, Carl-Johan Carlhäll, Peter Lundberg, Stergios Kechagias and Mattias Ekstedt

    Citation: BMC Gastroenterology 2021 21:180

    Content type: Study protocol

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  8. Acute pancreatitis (AP) lacks targeted prevention and treatment measures. Some key points in the pathogenesis of AP remain unclear, such as early activation of pancreatic enzymes. Several recent reports have s...

    Authors: Kun Li, Hongling Yin, Yi Duan, Peizhen Lai, Yancheng Cai and Youzhen Wei

    Citation: BMC Gastroenterology 2021 21:178

    Content type: Research article

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  9. Predicting imminent hepatocellular carcinoma (HCC) in liver cirrhotic patients is an unmet medical need. We aimed to investigate circulatory biomarkers and their optimum combinations in a prospective study.

    Authors: Kung-Hao Liang, Ming-Wei Lai, Yang-Hsiang Lin, Yu-De Chu, Chih-Lang Lin, Wey-Ran Lin, Ya-Hui Huang, Tong-Hung Wang, Rong-Nan Chien, Tsung-Hui Hu and Chau-Ting Yeh

    Citation: BMC Gastroenterology 2021 21:177

    Content type: Research article

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  10. Extracorporeal shock wave lithotripsy (ESWL) is a relatively safe and convenient mode of treatment for ureteral and renal stones, despite its relative safety; ESWL is not without its complications. We present ...

    Authors: Elaine N. Gitonga and Haitao Shen

    Citation: BMC Gastroenterology 2021 21:176

    Content type: Case report

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  11. There is a lack of studies regarding the optimal timing for endoscopic retrograde cholangiopancreatography (ERCP) in patients with cholangitis caused by distal malignant biliary obstruction (MBO). This study a...

    Authors: Namyoung Park, Sang Hyub Lee, Min Su You, Joo Seong Kim, Gunn Huh, Jung Won Chun, In Rae Cho, Woo Hyun Paik, Ji Kon Ryu and Yong-Tae Kim

    Citation: BMC Gastroenterology 2021 21:175

    Content type: Research article

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  12. Prevention and early detection of colorectal cancer (CRC) is a global priority, with many countries conducting population-based CRC screening programs. Although colonoscopy is the most accurate diagnostic meth...

    Authors: Chang Woo Kim, Hyunjin Kim, Hyoung Rae Kim, Bong-Hyeon Kye, Hyung Jin Kim, Byung Soh Min, Tae Jeong Oh, Sungwhan An and Suk-Hwan Lee

    Citation: BMC Gastroenterology 2021 21:173

    Content type: Study protocol

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  13. Physical activity may affect disease activity in patients with inflammatory bowel disease. We used a survey to investigate this association and performed interviews to get a better understanding of patient exp...

    Authors: Carlijn R. Lamers, Nicole M. de Roos, Lola J. M. Koppelman, Maria T. E. Hopman and Ben J. M. Witteman

    Citation: BMC Gastroenterology 2021 21:172

    Content type: Research article

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  14. The prevalence of Non-alcoholic fatty liver disease (NAFLD) is increasing and emerging as a global health burden. In addition to environmental factors, numerous studies have shown that genetic factors play an ...

    Authors: Yang fan Li, Jing Zheng, He wei Peng, Xiao lin Cai, Xin ting Pan, Hui quan Li, Qi zhu Hong, Zhi jian Hu, Yun li Wu and Xian-E. Peng

    Citation: BMC Gastroenterology 2021 21:171

    Content type: Research article

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  15. Causes of non-alcoholic fatty liver disease and its progression include visceral fat accumulation and loss of muscle mass; however, which of the two phenomena is more critical is unclear. Therefore, we intende...

    Authors: Teruki Miyake, Masumi Miyazaki, Osamu Yoshida, Sayaka Kanzaki, Hironobu Nakaguchi, Yoshiko Nakamura, Takao Watanabe, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Shinya Furukawa, Eiji Takeshita, Teru Kumagi, Yoshio Ikeda, Masanori Abe…

    Citation: BMC Gastroenterology 2021 21:170

    Content type: Research article

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  16. Surgical resection remains the best option for long-term survival in colorectal cancer (CRC); however, surgery can lead to tumor cell release into the circulation. Previous studies have also shown that surgery...

    Authors: Xing-Xing Liu, Jun Su, Yuan-yuan Long, Miao He and Zhao-Qiong Zhu

    Citation: BMC Gastroenterology 2021 21:169

    Content type: Research

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  17. Colorectum diversion with a proximal stoma is often the preferred surgical approach in patients with Crohn's disease-related anorectal lesions or refractory colitis. To date, few studies have assessed the inci...

    Authors: Hirosuke Kuroki, Akira Sugita, Kazutaka Koganei, Kenji Tatsumi, Ryo Futatsuki, Eiichi Nakao, Nao Obara and Katsuhiko Arai

    Citation: BMC Gastroenterology 2021 21:168

    Content type: Research

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  18. Defects in interleukin 10 (IL10) and its receptors are particularly involved in very early onset inflammatory bowel disease (VEOIBD). However, large fragment deletions of IL10 receptor A (IL10RA) are rare.

    Authors: Zifei Tang, Ping Zhang, Min Ji, Chunlan Yin, Ruiqin Zhao, Zhiheng Huang and Ying Huang

    Citation: BMC Gastroenterology 2021 21:167

    Content type: Research article

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  19. Clostridioides difficile (C. difficile) is a major nosocomial pathogen that infects the human gut and can cause diarrheal disease. A dominant risk factor is antibiotic treatment that disrupts the normal gut micro...

    Authors: Dana Binyamin, Orna Nitzan, Maya Azrad, Zohar Hamo, Omry Koren and Avi Peretz

    Citation: BMC Gastroenterology 2021 21:166

    Content type: Research article

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  20. Amyand’s hernia was an unusual condition defined by the presence of an appendix located in the inguinal hernia sac. Its prevalence was 1% of all inguinal hernia in children. The clinical manifestation of Amyan...

    Authors: Supangat, Henggar Allest Pratama, Nanda Eka Sri Sejati, Brenda Desy Romadhon and Ina Sulistyani

    Citation: BMC Gastroenterology 2021 21:165

    Content type: Case report

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  21. Hydatid cysts are parasitic zoonoses that often occur in the liver. Pancreatic hydatid cysts are very rare and are usually misdiagnosed as pancreatic cystadenomas. At present, surgical resection combined with ...

    Authors: Yilei Wu, Jun Gong, Wei Xiong, Xiaojiong Yu and Xiangyu Lu

    Citation: BMC Gastroenterology 2021 21:164

    Content type: Case report

    Published on:

  22. Deficiency of oxysterol 7α-hydroxylase, encoded by CYP7B1, is associated with fatal infantile progressive intrahepatic cholestasis and hereditary spastic paraplegia type 5. Most reported patients with CYP7B1 muta...

    Authors: Yun-Ping Tang, Jing-Yu Gong, Kenneth D. R. Setchell, Wujuan Zhang, Jing Zhao and Jian-She Wang

    Citation: BMC Gastroenterology 2021 21:163

    Content type: Case report

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  23. Intraductal tubulopapillary neoplasm (ITPN) of the pancreas is a new disease concept defined by the World Health Organization in 2010. ITPN progresses with tubulopapillary growth in the pancreatic duct and is ...

    Authors: Atsushi Yamaguchi, Takuro Hamada, Kaoru Wada, Riho Moriuchi, Kanae Tao, Hirona Konishi, Yuzuru Tamaru, Ryusaku Kusunoki, Toshio Kuwai, Hirotaka Kouno, Kohei Ishiyama, Naoto Hadano, Takeshi Sudo, Naoyuki Toyota, Junichi Zaitsu, Kazuya Kuraoka…

    Citation: BMC Gastroenterology 2021 21:162

    Content type: Case report

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  24. Ulcerative colitis (UC) is a chronic inflammatory bowel disease with recurrent episodes of debilitating symptoms negatively affecting work productivity and health-related quality of life (HRQoL). The use of bi...

    Authors: Niels Teich, Harald Grümmer, Eric Jörgensen, Thomas Liceni, Frank Holtkamp-Endemann, Tim Fischer and Susanne Hohenberger

    Citation: BMC Gastroenterology 2021 21:161

    Content type: Research article

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  25. Defining clinical phenotypes provides opportunities for new diagnostics and may provide insights into early intervention and disease prevention. There is increasing evidence that patient-derived health data ma...

    Authors: Tianyun Liu, Lichy Han, Mera Tilley, Lovisa Afzelius, Mateusz Maciejewski, Scott Jelinsky, Chao Tian, Matthew McIntyre, Nan Bing, Kenneth Hung and Russ B. Altman

    Citation: BMC Gastroenterology 2021 21:160

    Content type: Research article

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  26. Living with undiagnosed symptomatic coeliac disease is connected with deteriorated health, and persons with coeliac disease often wait a long time for their diagnosis. A mass screening would lower the delay, b...

    Authors: Fredrik Norström, Anna Myléus, Katrina Nordyke, Annelie Carlsson, Lotta Högberg, Olof Sandström, Lars Stenhammar, Anneli Ivarsson and Lars Lindholm

    Citation: BMC Gastroenterology 2021 21:159

    Content type: Research article

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  27. Systemic vasculitis associated with antineutrophil cytoplasmic autoantibodies (ANCA) have an extremely wide variety of symptoms, therefore the fast and proper diagnosis is difficult to establish even for exper...

    Authors: Nóra Ledó and Ákos Géza Pethő

    Citation: BMC Gastroenterology 2021 21:158

    Content type: Case report

    Published on:

  28. Clinically diagnosing high-grade (III–V) rectal prolapse might be difficult, and the prolapse can often be overlooked. Even though defecography is the significant diagnostic tool for rectal prolapse, it is not...

    Authors: Byung-Soo Park, Sung Hwan Cho, Gyung Mo Son, Hyun Sung Kim, Yong-Hoon Cho, Dae Gon Ryu, Su Jin Kim, Su Bum Park, Cheol Woong Choi, Hyung Wook Kim, Tae Un Kim, Dong Soo Suh, Myunghee Yoon and Hong Jae Jo

    Citation: BMC Gastroenterology 2021 21:157

    Content type: Research article

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  29. Primary hepatic angiosarcoma is a very rare and highly malignant tumor with poor prognosis. It is difficult to diagnose because of the lack of typical clinical features, and the treatment protocols for PHA are...

    Authors: Lei Jiang, Lijun Xie, Ge Li, Hang Xie, Zhao Fang, Xinran Cai and Yanling Chen

    Citation: BMC Gastroenterology 2021 21:156

    Content type: Research article

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  30. Accurate characterization of small nodules in a cirrhotic liver is challenging. We aimed to determine the additive value of MRI-based radiomics analysis to Liver Imaging Reporting and Data System version 2018 ...

    Authors: Xi Zhong, Tianpei Guan, Danrui Tang, Jiansheng Li, Bingui Lu, Shuzhong Cui and Hongsheng Tang

    Citation: BMC Gastroenterology 2021 21:155

    Content type: Research article

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  31. Acute mesenteric ischemia (AMI) is a life-threatening condition. However, there is no accurate method to predict intestinal necrosis in AMI patients that may facilitate early surgical intervention. This study ...

    Authors: Xinsuo Zhuang, Fumei Chen, Qian Zhou, Yuanrun Zhu and Xiaofeng Yang

    Citation: BMC Gastroenterology 2021 21:154

    Content type: Research article

    Published on:

  32. The role of radiotherapy for cT4bNanyM0 esophageal squamous cell carcinoma (ESqCC) is relatively unclear, with both chemotherapy (C/T) alone and definitive concurrent chemoradiotherapy (dCCRT) being treatment ...

    Authors: Chia-Chin Li, Chih-Yi Chen, Ying-Hsiang Chou, Chih-Jen Huang, Hsiu-Ying Ku and Chun-Ru Chien

    Citation: BMC Gastroenterology 2021 21:153

    Content type: Research article

    Published on:

  33. Although the association between eating habits which can be modified and digestive diseases has been reported, to date, no research has evaluated the association between eating habits and ulcerative colitis (U...

    Authors: Shinya Furukawa, Sen Yagi, Kana Shiraishi, Yu Hashimoto, Shogo Kitahata, Masakazu Hanayama, Kazuhiro Tange, Kenichiro Mori, Tomoyuki Ninomiya, Seiyuu Suzuki, Naozumi Shibata, Hidehiro Murakami, Katsuhisa Ohashi, Aki Hasebe, Hideomi Tomida, Yasunori Yamamoto…

    Citation: BMC Gastroenterology 2021 21:152

    Content type: Research article

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  34. Ectopic pancreas (EP) is defined as pancreatic tissue that lacks anatomical or vascular communication with the normal body of the pancreas. Despite improvements in diagnostic endoscopy and imaging studies, dif...

    Authors: Xuemei Liu, Xinglong Wu, Biguang Tuo and Huichao Wu

    Citation: BMC Gastroenterology 2021 21:151

    Content type: Case report

    Published on:

  35. Quantification of circulating organ-specific cell-free DNA (cfDNA) provides a sensitive measure of ongoing cell death that could benefit evaluation of the cholestatic liver diseases primary biliary cholangitis...

    Authors: Sohan Punia, Brian D. Juran, Ahmad H. Ali, Erik M. Schlicht, Raymond M. Moore, Zhifu Sun and Konstantinos N. Lazaridis

    Citation: BMC Gastroenterology 2021 21:149

    Content type: Research article

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  36. Antiphospholipid syndrome (APS) is an acquired pre-thrombotic autoimmune condition, which produces autoantibodies called antiphospholipid antibodies (APL) against phospholipid-binding plasma proteins. The diag...

    Authors: Xiaojuan Zou, Zhongqi Fan, Ling Zhao, Weiling Xu, Jin Zhang and Zhenyu Jiang

    Citation: BMC Gastroenterology 2021 21:148

    Content type: Case report

    Published on:

  37. Existing proposed classification systems for the Papilla of Vater (PV) suboptimally account for all relevant, encountered PV appearances, are too complex or have not been assessed for intra- or interobserver v...

    Authors: Jorge Canena, Luís Lopes, João Fernandes, Patrício Costa, Marianna Arvanitakis, Arjun D. Koch, Jan-Werner Poley, Javier Jimenez, Enrique Dominguez-Munõz, Pietro Familiari, Marco J. Bruno and Mário Dinis-Ribeiro

    Citation: BMC Gastroenterology 2021 21:147

    Content type: Research article

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  38. Angiogenesis is a key factor in promoting tumor growth, invasion and metastasis. In this study we aimed to investigate the prognostic value of angiogenesis-related genes (ARGs) in gastric cancer (GC).

    Authors: Sheng Zheng, Zizhen Zhang, Ning Ding, Jiawei Sun, Yifeng Lin, Jingyu Chen, Jing Zhong, Liming Shao, Zhenghua Lin and Meng Xue

    Citation: BMC Gastroenterology 2021 21:146

    Content type: Research article

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  39. Liver transplantation is the only curative treatment for patients with end-stage liver disease. Short-term survival has improved due to improved surgical techniques and greater efficacy of immunosuppressive dr...

    Authors: Magda Teresa Thomsen, Julie Høgh, Andreas Dehlbæk Knudsen, Anne Marie Reimer Jensen, Marco Gelpi, Gerda E. Villadsen, Rozeta Abazi, Peter Holland-Fischer, Lars Køber, Otto Clemmesen, Paul Suno Krohn, Jens Hillingsø, Tina Vilsbøll, Tor Biering-Sørensen, Klaus Fuglsang Kofoed, Børge Grønne Nordestgaard…

    Citation: BMC Gastroenterology 2021 21:145

    Content type: Study protocol

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  40. Non-alcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular risk irrespective of conventional risk factors. The role of gut-liver interaction is implicated in its development. We inve...

    Authors: Pui Lin Chong, David Laight, Richard J. Aspinall, Antony Higginson and Michael H. Cummings

    Citation: BMC Gastroenterology 2021 21:144

    Content type: Research article

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  41. Alcohol use disorders (AUD) cause 7.2% of UK hospital admissions/year. Most are not managed by hepatologists and liver disease may be missed. We used the Enhanced Liver Fibrosis (ELF) test to investigate preva...

    Authors: Freya Rhodes, Sara Cococcia, Jasmina Panovska-Griffiths, Sudeep Tanwar, Rachel H. Westbrook, Alison Rodger and William M. Rosenberg

    Citation: BMC Gastroenterology 2021 21:143

    Content type: Research article

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  42. The preoperative prediction of post hepatectomy liver failure (PHLF) is essential, but there is no gold standard for the prediction at present, and the efficacy of different methods for the prediction has not ...

    Authors: Rong Fu, Tingting Qiu, Wenwu Ling, Qiang Lu and Yan Luo

    Citation: BMC Gastroenterology 2021 21:142

    Content type: Research article

    Published on:

  43. Ulcerative colitis (UC) has a relapsing and remitting pattern, wherein the underlying mechanisms of the relapse might involve an enhanced uptake of luminal antigens which stimulate the immune response. The tri...

    Authors: Jia-Chen E. Hu, Franziska Weiß, Christian Bojarski, Federica Branchi, Jörg-Dieter Schulzke, Michael Fromm and Susanne M. Krug

    Citation: BMC Gastroenterology 2021 21:141

    Content type: Research article

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  44. Our knowledge of the incidence and prevalence of inflammatory bowel disease (IBD) is uncertain. Recent studies reported an increase in prevalence. However, they excluded a high proportion of ambiguous cases fr...

    Authors: Karoline Freeman, Ronan Ryan, Nicholas Parsons, Sian Taylor-Phillips, Brian H. Willis and Aileen Clarke

    Citation: BMC Gastroenterology 2021 21:139

    Content type: Research article

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  45. Laparoscopic anatomic hepatectomy (LAH) has gradually become a routine surgical procedure. However, how to expose the whole hepatic vein and avoid the hepatic vein laceration is still a challenge because of th...

    Authors: Shaohe Wang, Yang Yue, Wenjie Zhang, Qiaoyu Liu, Beicheng Sun, Xitai Sun and Decai Yu

    Citation: BMC Gastroenterology 2021 21:138

    Content type: Technical advance

    Published on:

  46. Despite constipation being a common clinical condition in older adults, the clinical relevance of constipation related to frailty is less studied. Hence, we aimed to investigate the association between chronic...

    Authors: Jihye Lim, Hyungchul Park, Heayon Lee, Eunju Lee, Danbi Lee, Hee-Won Jung and Il-Young Jang

    Citation: BMC Gastroenterology 2021 21:137

    Content type: Research article

    Published on:

Annual Journal Metrics

  • Speed
    78 days to first decision for reviewed manuscripts only
    60 days to first decision for all manuscripts
    198 days from submission to acceptance
    15 days from acceptance to publication

    Citation Impact
    2.489 - 2-year Impact Factor
    2.796 - 5-year Impact Factor
    1.018 - SNIP (Source-Normalized Impact per Paper)
    0.957 - SJR (SCImago Journal Rank)

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