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  1. Portal hypertension is a common complication of chronic liver diseases responsible for most liver cirrhosis consequences. In patients with portal hypertension, oesophagogastric variceal bleeding is a leading c...

    Authors: Ling Mei, Ying Ma, Lili Zhao, Qingling Chen, Li Zhou, Hang Yang, Jie Liu and Jia Li
    Citation: BMC Gastroenterology 2022 22:515
    Content type: Research Published on:

    The Correction to this article has been published in BMC Gastroenterology 2023 23:99

  2. Colorectal cancer (CRC) has been regarded as one of the most frequently diagnosed malignancies among the leading causes of cancer-related morbidity and mortality globally. Diagnosis of CRC at the early-stages ...

    Authors: Maedeh Amini, Sama Rezasoltani, Mohamad Amin Pourhoseingholi, Hamid Asadzadeh Aghdaei and Mohammad Reza Zali
    Citation: BMC Gastroenterology 2022 22:514
    Content type: Research Published on:

  3. The hormone-dependent effect of MAP3K1 gene polymorphisms may explain sex-specific differences in gastric cancer (GC) risk. Phytoestrogens have been shown to interact with this genetic factor. Here, we investigat...

    Authors: Jung Hyun Kwak, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi and Hyun Ja Kim
    Citation: BMC Gastroenterology 2022 22:513
    Content type: Research Published on:

  5. The clinical impact of single-incision laparoscopic surgery (SILS) for descending colon cancer (DCC) is unclear. The aim of this study was to evaluate the clinical outcomes of SILS for DCC compared with multi-...

    Authors: Mitsuyoshi Tei, Yozo Suzuki, Toshinori Sueda, Kazuya Iwamoto, Atsushi Naito, Masatoshi Nomura, Yukihiro Yoshikawa, Masahisa Ohtsuka, Mitsunobu Imasato, Tsunekazu Mizushima and Hiroki Akamatsu
    Citation: BMC Gastroenterology 2022 22:511
    Content type: Research Published on:

  6. For patients with unresectable hepatocellular carcinoma (uHCC), intensity-modulated radiotherapy (IMRT) has become one of the options for clinical local treatment. Immune parameters, including platelet-to-lymp...

    Authors: Jian-Xu Li, Mei-Ling He, Mo-Qin Qiu, Liu-Ying Yan, Mei-Ying Long, Jian-Hong Zhong, Rui-Jun Zhang, Chun-Feng Liang, Ya-Dan Pang, Jun-Kun He, Qian-Qian Chen, Jin-Xia Weng, Shi-Xiong Liang and Bang-De Xiang
    Citation: BMC Gastroenterology 2022 22:510
    Content type: Research article Published on:

  7. The best intervention approach for residual choledocholithiasis after choledocholithotomy T-tube drainage remains controversial, especially during the period of indwelling T tube and the formation of a sinus. ...

    Authors: Li Zhang, Lu Li, Junfang Yao, Feifei Chu, Yong Zhang and Huili Wu
    Citation: BMC Gastroenterology 2022 22:509
    Content type: Research Published on:

  8. Liver biopsy is the reference standard for assessing liver fibrosis. Moreover, it is an invasive procedure. Transient elastography (TE) is an accurate, noninvasive method for evaluating liver stiffness as a su...

    Authors: A ElShahawy, MS El-Raziky, SA Sharaf, A Elsharkawy, A Enayet and H Taher
    Citation: BMC Gastroenterology 2022 22:508
    Content type: Research article Published on:

  9. As a gram-negative and microaerophilic bacterium, Helicobacter pylori (HP) is the main cause of chronic gastritis. Therefore, considering the high prevalence of HP infection worldwide, as well as the increasing p...

    Authors: Pezhman Alavinejad, Eskandar Hajiani, Abazar Parsi, Azam Satari, Mohammad Javad Rezaei, Morteza Nayebi, Ahmad Hormati, Omid Eslami, Mohammed Hussien Ahmed, Quang Trung Tran, Masoud Arshadzadeh, Siamak Baghaei, Samira Mohammadi, Seyed Jalal Hashemi and Alireza Sedaghat
    Citation: BMC Gastroenterology 2022 22:507
    Content type: Research Published on:

  11. Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed cancer and third leading cause of cancer-related death worldwide in 2020. Exosomes derived from cancer-associated fibroblasts (CAFs-exo) can ...

    Authors: An-Li Jin, Lin Ding, Wen-Jing Yang, Te Liu, Wei Chen, Tong Li, Chun-Yan Zhang, Bai-Shen Pan, Shuang-Jian Qiu, Jian Zhou, Jia Fan, Wei Guo, Xin-Rong Yang and Bei-Li Wang
    Citation: BMC Gastroenterology 2022 22:505
    Content type: Research Published on:

  12. Deficiencies in Mismatch Repair (MMR) proteins are one of the major pathways in the development of colorectal cancer (CRC). MMR status evaluation is recommended in every new CRC patient. However, this is not f...

    Authors: Shai Farkash, Naama Schwartz, Natalia Edison, Sophia Greenberg, Hila Belhanes Peled, Wail Sindiany and Judit Krausz
    Citation: BMC Gastroenterology 2022 22:504
    Content type: Research article Published on:

  13. The analysis of circulating tumor cell-associated white blood cell (CTC-WBC) clusters represented the progress in the liquid biopsy of malignant tumors, however, related research in patients with colorectal ca...

    Authors: Yifan Xu, Qianlong Zhang, Zhou Xu, Qingfeng Xie, Wenfu Ding, Hao Liu and Haijun Deng
    Citation: BMC Gastroenterology 2022 22:503
    Content type: Research Published on:

  14. Previous studies have shown that the Kyoto classification of gastritis can accurately predict H. pylori infection status on conventional gastroscopy. The aim of this study was to test whether the Kyoto classifica...

    Authors: Sun Xi, Liu Jing, Wu Lili, Li Tingting, Li Jun, Wang Ming, Wang Zhiqiang and Jin Peng
    Citation: BMC Gastroenterology 2022 22:502
    Content type: Research Published on:

  15. Determining the relative cost-effectiveness between advanced therapeutic options for ulcerative colitis (UC) may optimize resource utilization. We evaluated total cost per response, cost per remission, and cos...

    Authors: Vipul Jairath, Russell D. Cohen, Edward V. Loftus Jr., Ninfa Candela, Karen Lasch and Bob G. Schultz
    Citation: BMC Gastroenterology 2022 22:501
    Content type: Research Article Published on:

  16. A cross-sectional association between the combination indicator of high-density lipoprotein cholesterol (HDL-C) and gamma-glutamyl transferase (GGT) and fatty liver has been described in several recent studies...

    Authors: Qiyang Xie, Song Lu, Maobin Kuang, Shiming He, Changhui Yu, Chong Hu and Yang Zou
    Citation: BMC Gastroenterology 2022 22:500
    Content type: Research Published on:

  17. MicroRNAs (miRNAs) play an important role in various diseases, including HCV infection, the aim of the current study was to evaluate the potential use of serum miRNAs as biomarkers for diagnosis, prognosis, an...

    Authors: Noha Anwar Hassuna, Aya Nabil Gamil, Mahmoud Shokry Mahmoud, Wafaa Khairy Mohamed and Rasha Khairy
    Citation: BMC Gastroenterology 2022 22:499
    Content type: Research Published on:

  18. No study has performed a face-to-face comparison of biologics after the failure of the first anti-TNF agent in patients with Crohn’s disease (CD). The aim of the study was to compare the efficacy of biologics ...

    Authors: Cassandra Rayer, Maria Nachury, Arnaud Bourreille, Xavier Roblin, Laurent Peyrin-Biroulet, Stephanie Viennot, Mathurin Flamant, David Laharie, Bénédicte Caron, Marie Dewitte, Laurent Siproudhis, Mathurin Fumery and Guillaume Bouguen
    Citation: BMC Gastroenterology 2022 22:498
    Content type: Research Published on:

    The Correction to this article has been published in BMC Gastroenterology 2023 23:31

  19. Endoscopic retrograde cholangiopancreatography (ERCP) in patients with situs inversus totalis (SIT) is rarely understood due to its rarity. Patient position and endoscope manipulation were the main concerns in...

    Authors: Bin Ding, Jun Wang, Xing Wei, Yu Du, Liang Xia, Chenyi Sun, Kun Han, Xue Yang, Xuegang Guo, Yanglin Pan and Xiangping Wang
    Citation: BMC Gastroenterology 2022 22:497
    Content type: Research Published on:

  20. Gastric cancer is one of the leading cancer-related death causes. Enormous efforts have been focused on this field in these years. However, clinical trial failure is becoming a massive obstacle for researchers...

    Authors: Zikai Zhang, Junyi Yin, Yang Yue, Yang Su and Hong Jiang
    Citation: BMC Gastroenterology 2022 22:496
    Content type: Research Published on:

    The Correction to this article has been published in BMC Gastroenterology 2023 23:38

  22. CF patients experience several episodes of pulmonary exacerbations and reduction in their lung function progressively. Lung function is not the only diagnostic index by physicians to decide if CF patients requ...

    Authors: Farid Imanzadeh, Fatemeh Kerami, Maryam Hassanzad, Amirhossein Hosseini, Mahmoud Hajipour, Ghamartaj Khanbabaee, Naghi Dara, Katayoun Khatami, Nazanin Farahbakhsh and Aliakbar Sayyari
    Citation: BMC Gastroenterology 2022 22:494
    Content type: Research Published on:

  23. Gastrointestinal cancers are a critical global cancer burden, and tracking their trends would inform the health policies.

    Authors: Danfeng Yu, Zejin Ou, Wenni Zhang, Huan He, Yongzhi Li, Wenqiao He, Minyi Zhang, Yuhan Gao, Fei Wu and Qing Chen
    Citation: BMC Gastroenterology 2022 22:493
    Content type: Research Published on:

  24. Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is one of the most frequent gastrointestinal disorders worldwide. Although the actual etiology of IBD remains unclear, growin...

    Authors: Dongjie Li, Liyuan Liu, Xiancai Du, Wen Ma, Jing Zhang and Wenhua Piao
    Citation: BMC Gastroenterology 2022 22:492
    Content type: Research Published on:

  26. Although eradication therapy for chronic Helicobacter pylori (H. pylori) reduces the risk of gastric cancer (GC), its effectiveness is not complete. Therefore, it is also critically important to identifying those...

    Authors: Yuka Hirashita, Masahide Fukuda, Masaaki Kodama, Yoshiyuki Tsukamoto, Tadayoshi Okimoto, Kazuhiro Mizukami, Yoshinari Kawahara, Yasuhiro Wada, Sotaro Ozaka, Kazumi Togo, Keisuke Kinoshita, Takafumi Fuchino, Kensuke Fukuda, Kazuhisa Okamoto, Ryo Ogawa, Osamu Matsunari…
    Citation: BMC Gastroenterology 2022 22:490
    Content type: Research Published on:

  27. The unknown aetiology of Serrated Polyposis Syndrome (SPS) impedes risk prediction and prevention. We investigated risk factors for SPS, overall and stratified by World Health Organization (WHO)2010 clinical crit...

    Authors: Emma Anthony, Jeanette C. Reece, Elasma Milanzi, Jihoon E. Joo, Sharelle Joseland, Mark Clendenning, Amanda Whelan, Susan Parry, Julie Arnold, Varnika Vijay, Nathan Atkinson, John L. Hopper, Aung K. Win, Mark A. Jenkins, Finlay A. Macrae, Ingrid M. Winship…
    Citation: BMC Gastroenterology 2022 22:489
    Content type: Research article Published on:

  28. There are many well-described potential gastrointestinal (GI) side effects of pancreatic resection that can cause patients to suffer from chronic malabsorption, diarrhea, and persistent nausea. These GI sympto...

    Authors: Rebecca Bromley-Dulfano, Auriel T. August, Amy Y. Li, Walter Park and Brendan Visser
    Citation: BMC Gastroenterology 2022 22:488
    Content type: Research article Published on:

  29. Inflammatory bowel disease (IBD) is a chronic systemic inflammatory condition that debilitate the quality of life. Multimorbidity, a concept only beginning to emerge in IBD, is defined as two or more comorbidi...

    Authors: Mahmoud H. Mosli, Majid Alsahafi, Mohammad N Alsanea, Faisal Alhasani, Mohammad Ahmed and Omar Saadah
    Citation: BMC Gastroenterology 2022 22:487
    Content type: Research article Published on:

  30. Enterocutaneous fistula after removal of the jejunostomy tube leads to multiple problems, such as cosmetic problems, decreased quality of life, electrolyte imbalances, infectious complications, and increased m...

    Authors: Teppei Kamada, Hironori Ohdaira, Keigo Nakashima, Ryo Nishide, Junji Takahashi, Eisaku Ito, Yuichi Nakaseko, Norihiko Suzuki, Masashi Yoshida, Ken Eto and Yutaka Suzuki
    Citation: BMC Gastroenterology 2022 22:486
    Content type: Research Published on:

  31. Ulcerative colitis (UC) is a chronic idiopathic inflammatory disorder affecting the large intestine. Inflammatory biomarkers in UC are nonspecific, simple and cheap biomarker is needed. Our study aimed to expl...

    Authors: Wan Feng, Yajun Liu, Lei Zhu, Luzhou Xu and Hong Shen
    Citation: BMC Gastroenterology 2022 22:485
    Content type: Research Published on:

  32. To date, no study has evaluated trends in the burden of alcohol-induced cirrhosis and other chronic liver diseases based on the Global Burden of Diseases, Injuries, and Risk Factors (GBD) 2019 study. Herein, w...

    Authors: Xiansheng Zhang, Xin Zhang, Meilian Liu, Lin Zhu and Zhuokai He
    Citation: BMC Gastroenterology 2022 22:484
    Content type: Research Published on:

  33. Non-alcoholic simple fatty liver disease patients have very low compliance with almost all types of physical activities. A transtheoretical model-oriented lifestyle modification plan awakens the patient’s cons...

    Authors: Lijuan Li, Kun Hou, Mengya Yuan, Yan Zhang and Yang Zhang
    Citation: BMC Gastroenterology 2022 22:483
    Content type: Research Published on:

  34. Previous studies have reported that the tumor heterogeneity and complex oncogenic mechanisms of proximal and distal colon cancer (CRC) are divergent. Therefore, we aim to analyze the differences between left-s...

    Authors: Mengye Niu, Chengyang Chen, Xian Gao, Yi Guo, Bingzhou Zhang, Xin Wang, Shihao Chen, Xupeng Niu, Chao Zhang, Like Li, Zhongxin Li, Zengren Zhao and Xia Jiang
    Citation: BMC Gastroenterology 2022 22:482
    Content type: Research Published on:

  35. The mesorectum surrounding the rectum provides an ideal substrate for tumour spread. However, preoperative risk assessment is still an issue. This study aimed to investigate the microstructural features of mes...

    Authors: Bao-Lan Lu, Yan Chen, Zi-Qiang Wen, Yi-Yan Liu, Yu-Ru Ma, Yu-Tao Que, Zhi-Wen Zhang, Xue-Han Wu and Shen-Ping Yu
    Citation: BMC Gastroenterology 2022 22:481
    Content type: Research Published on:

  36. Invasive gastrointestinal surgery may be performed as an open or endoscopic procedure, such as laparoscopic semi-colon surgery, laparoscopic appendectomy, laparoscopic gastrectomy, and anal surgery, among othe...

    Authors: Huyen Thi Nguyen, Quynh Thi Huong Bui, Tam Van Vo, Hien Thi Thu Pham and Thong Duy Vo
    Citation: BMC Gastroenterology 2022 22:480
    Content type: Research Published on:

  38. Non-alcoholic fatty liver disease (NAFLD) is usually asymptomatic and lacks a specific biomarker; therefore, many individuals might remain undiagnosed even with advanced liver fibrosis. The aim of this study w...

    Authors: Shunsuke Sato, Hidehiko Kawai, Sho Sato, Hirohiko Iwasaki, Masashi Omori, Yuji Kita, Yuji Ikeda, Takahito Awatsu, Ayato Murata, Gentaro Taniguchi, Yuji Shimada and Takuya Genda
    Citation: BMC Gastroenterology 2022 22:478
    Content type: Research Published on:

  39. The epidemiology of Crohn’s disease (CD) has changed over the past decades, demonstrating a trend toward increased prevalence in developing countries, while in developed countries, its incidence has stabilized...

    Authors: Ahmed Al Qteishat, Kiril Kirov and Dmitry Bokov
    Citation: BMC Gastroenterology 2022 22:477
    Content type: Research Published on:

  40. It has not yet been determined whether gastroscopy and colonoscopy screening help patients with gallbladder diseases. We aim to retrospectively investigate the relationship between gallbladder diseases and gas...

    Authors: Wenbin Geng, Xiangrong Qin, Peng Yang, Junmei Wang, Jing Yu and Xiaoyong Wang
    Citation: BMC Gastroenterology 2022 22:476
    Content type: Research Published on:

  41. The influence of alcoholic liver disease (ALD) on the postoperative outcomes is not completely understood. Our purpose is to evaluate the complications and mortality after nonhepatic surgeries in patients with...

    Authors: Hsin-Yun Wu, Chuen-Chau Chang, Chun-Chieh Yeh, Ming-Yao Chen, Yih-Giun Cherng, Ta-Liang Chen and Chien-Chang Liao
    Citation: BMC Gastroenterology 2022 22:475
    Content type: Research Published on:

  42. Although various treatments help reduce abdominal pain, real-world pain medication utilization among patients with Crohn’s disease (CD) or ulcerative colitis (UC) receiving advanced therapies is poorly underst...

    Authors: Theresa Hunter, April N. Naegeli, Chi Nguyen, Mingyang Shan, Joseph L. Smith, Hiangkiat Tan, Klaus Gottlieb and Keith Isenberg
    Citation: BMC Gastroenterology 2022 22:474
    Content type: Research Published on:

  43. Main pancreatic duct (MPD) dilation is a high-risk stigmata/worrisome feature of malignancy in intraductal papillary mucinous neoplasms (IPMNs). The threshold of MPD diameter in predicting malignancy may be re...

    Authors: Hao Zhou, Xiaoshuang Li, Yajie Wang, Zhiyue Wang, Jingrong Zhu, Zhongqiu Wang and Xiao Chen
    Citation: BMC Gastroenterology 2022 22:473
    Content type: Research Published on:

  44. Little evidence is available in terms of the role of dietary antioxidants in the management of irritable bowel syndrome (IBS) disease. This study aimed to examine the association between dietary total antioxid...

    Authors: Solaleh Saneie, Azadeh Aminianfar, Farzad Shidfar, Ammar Hassanzadeh Keshteli, Ahmad Esmaillzadeh and Peyman Adibi
    Citation: BMC Gastroenterology 2022 22:472
    Content type: Research Published on:

  45. A recently proposed diagnostic criteria of metabolic dysfunction-associated fatty liver disease (MAFLD) is more available for various clinical situations than nonalcoholic fatty liver disease (NAFLD), but unde...

    Authors: Qiling Liu, Gang Zhao, Qian Li, Weiyun Wu, Yan Zhang and Hua Bian
    Citation: BMC Gastroenterology 2022 22:471
    Content type: Research Published on:

  46. The aim of this study was to investigate the efficacy and safety of the combination of low-molecular-weight heparin + dexamethasone after partial splenic embolization in cirrhotic patients with massive splenom...

    Authors: Haohao Lu, Chuansheng Zheng, Bin Xiong and Xiangwen Xia
    Citation: BMC Gastroenterology 2022 22:470
    Content type: Research Published on:

    The Correction to this article has been published in BMC Gastroenterology 2023 23:27

  47. Triclosan, an antimicrobial agent in personal care products, could be absorbed into the human body through the digestive tract. This animal experiment aimed to clarify the effects of triclosan exposure on the ...

    Authors: Jing Liu, Yang Tao, Wang Haikun, Yang Lanfang, Lu Jingyi and Yao Ping
    Citation: BMC Gastroenterology 2022 22:469
    Content type: Research Published on:

  48. The timing of nutritional assessment may be important to treat cancer patients and predict their prognosis. This study examined whether Patient-Generated Subjective Global Assessment (PG-SGA) and NUTRISCORE sc...

    Authors: Jae Won Cho, Jiyoung Youn, Eun Mee Kim, Min-Gew Choi and Jung Eun Lee
    Citation: BMC Gastroenterology 2022 22:468
    Content type: Research Published on:

  49. Gastrointestinal (GI) bleeding is one of the most impactful complications in patients hospitalized from COVID-19 infection. Limited study has focused on patients with upper GI bleeding (UGIB). This study aimed...

    Authors: Thaninee Prasoppokakorn, Pinit Kullavanijaya and Rapat Pittayanon
    Citation: BMC Gastroenterology 2022 22:465
    Content type: Research Published on:

  50. Biological therapy for inflammatory bowel disease is efficient in many cases but not all. The underlying molecular mechanisms behind non-response to biological therapy in inflammatory bowel disease are poorly ...

    Authors: Rasmus Goll, Øystein K. Moe, Kay-Martin Johnsen, Renate Meyer, Joachim Friestad, Mona D. Gundersen, Hege Kileng, Knut Johnsen and Jon R. Florholmen
    Citation: BMC Gastroenterology 2022 22:464
    Content type: Research Published on:
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BMC Gastroenterology

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