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  1. The aim of this study is to explore the treatment strategies being followed for patients with obstructing colorectal cancer (OCRC) at our institute and to know the management outcomes.

    Authors: Abhijeet Kumar, Sajan Babu Dhungana, Rakesh Kumar Gupta, Suresh Prasad Sah and Bhawani khanal
    Citation: BMC Gastroenterology 2022 22:303
  2. Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis characterized by infiltration of lipid-laden foamy macrophages within different tissues. Clinical manifestations of ECD are hig...

    Authors: Jia-wen Dai, Tian-hua He, Ming-hui Duan, Yue Li and Xin-xin Cao
    Citation: BMC Gastroenterology 2022 22:302
  3. The ABC score is a new pre-endoscopic scoring system that was recently developed to accurately predict one-month mortality in upper and lower gastrointestinal bleeding (GIB). We aim to validate this new score ...

    Authors: Marie Christelle Saade, Anthony Kerbage, Suha Jabak, Maha Makki, Kassem Barada and Yasser Shaib
    Citation: BMC Gastroenterology 2022 22:301
  4. Small intestinal bacterial overgrowth (SIBO) is a condition of unknown prevalence characterized by an excessive amount of bacteria in the small bowel, typically resulting in vague gastrointestinal symptoms wit...

    Authors: Majd B. Aboona, Tina W. Wong, Paul R. Del Prado, Keith Paley, Ross F. Goldberg, Samuel Weimer, Harikrishna Dave, Dan Hobohm and Adam Smith
    Citation: BMC Gastroenterology 2022 22:300
  5. Gastric cancer remains a severe public health problem worldwide, particularly in Japan. Recent studies have demonstrated that serum markers are beneficial for risk stratification in gastric cancer development....

    Authors: Naoko Nagasaki, Masanori Ito, Tomoyuki Boda, Takahiro Kotachi, Hidehiko Takigawa, Shiro Oka and Shinji Tanaka
    Citation: BMC Gastroenterology 2022 22:299
  6. Authors: Ulrike Ries Feddersen, Sebastian Kjærgaard Hendel, Mark Alexander Berner-Hansen, Thomas Andrew Jepps, Mark Berner-Hansen and Niels Bindslev
    Citation: BMC Gastroenterology 2022 22:298

    The original article was published in BMC Gastroenterology 2022 22:234

  7. A precise evaluation of liver reserve function in patients with hepatic alveolar echinococcosis (HAE) prior to hepatectomy could substantially increase the success rate of the operation and reduce the incidenc...

    Authors: Yuxin Liang, Zilong Zhang, Zonglin Dai, Rui Cao, Deyuan Zhong, Chunyou Lai, Yutong Yao, Tianhang Feng and Xiaolun Huang
    Citation: BMC Gastroenterology 2022 22:297
  8. To compare the prognosis of first-line systemic chemotherapy of AS (Albumin-bound paclitaxel and S-1) versus SOX (S-1 and oxaliplatin) regimen in Chinese gastric cancer patients with peritoneal metastasis.

    Authors: Lingyun Zhang, Jiayu Zhang, Yan Wang, Wei Li, Shan Yu, Qian Li, Yiyi Yu, Tianshu Liu and Yuehong Cui
    Citation: BMC Gastroenterology 2022 22:296
  9. Heterogeneity of liver function and tumor burden in intermediate-stage hepatocellular carcinoma (HCC) results in different outcomes after transarterial chemoembolization (TACE). Easy albumin-bilirubin (EZ-ALB...

    Authors: Prooksa Ananchuensook, Supachaya Sriphoosanaphan, Sirinporn Suksawatamnauy, Nipaporn Siripon, Nutcha Pinjaroen, Nopavut Geratikornsupuk, Stephen J. Kerr, Kessarin Thanapirom and Piyawat Komolmit
    Citation: BMC Gastroenterology 2022 22:295
  10. The endoscopic features of oxyntic gland adenoma and gastric adenocarcinoma of the fundic gland type have not been fully investigated in relation to Helicobacter pylori infection status. We compared the morpholog...

    Authors: Masaya Iwamuro, Chiaki Kusumoto, Masahiro Nakagawa, Kazuhiro Matsueda, Sayo Kobayashi, Masao Yoshioka, Tomoki Inaba, Tatsuya Toyokawa, Chihiro Sakaguchi, Shouichi Tanaka, Takehiro Tanaka and Hiroyuki Okada
    Citation: BMC Gastroenterology 2022 22:294
  11. In recent years, the incidence of rectal neuroendocrine tumors (NET)s has markedly increased due to the widespread use of screening colonoscopy. However, many patients are referred from local clinics after und...

    Authors: Boram Cha, Jongbeom Shin, Weon Jin Ko, Kye Sook Kwon and Hyungkil Kim
    Citation: BMC Gastroenterology 2022 22:293
  12. Malignant peritoneal mesothelioma (MPM) is a rare disease characterized by atypical symptoms, difficult diagnosis, variable course and poor prognosis, and it develops mainly in elderly individuals. The authors...

    Authors: Dan Pan, Mengyao Wang, Wencheng Liu, Yan Li, Lixuan Sang and Bing Chang
    Citation: BMC Gastroenterology 2022 22:292
  13. There are limited comparative data for infliximab and vedolizumab in inflammatory bowel disease patients.

    Authors: Laurent Peyrin-Biroulet, Perttu Arkkila, Alessandro Armuzzi, Silvio Danese, Jordi Guardiola, Jørgen Jahnsen, Charles Lees, Edouard Louis, Milan Lukáš, Walter Reinisch, Xavier Roblin, Minyoung Jang, Han Geul Byun, Dong-Hyeon Kim, Sung Jeong Lee and Raja Atreya
    Citation: BMC Gastroenterology 2022 22:291
  14. Physical activity in paediatric and young adult patients suffering from inflammatory bowel disease (IBD) may play an important role in the overall health status. However, physical activity in these patients ha...

    Authors: Ken Lund, Michael Due Larsen, Torben Knudsen, Jens Kjeldsen, Rasmus Gaardskær Nielsen, Søren Brage and Bente Mertz Nørgård
    Citation: BMC Gastroenterology 2022 22:290
  15. Pancreatic acinar cell metaplasia (PACM) has been rarely reported in the gastric mucosa. In the present study, we aimed to elucidate the clinical and pathological characteristics of PACM associated with Helicobac...

    Authors: Takafumi Fuchino, Yasuhiro Wada, Masaaki Kodama, Ken-ichi Mukaisho, Kazuhiro Mizukami, Tadayoshi Okimoto, Ryoji Kushima and Kazunari Murakami
    Citation: BMC Gastroenterology 2022 22:289
  16. Intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC) are the most prevalent histologic types of primary liver cancer. HCC and ICC differ in treatment and prognosis, warranting an effective ...

    Authors: Xin Zhang, Wen-Juan Huang, Meng-Lin Zhang, Wen Wang, Ye Niu, Rui-tao Wang and Zeng-yao Liu
    Citation: BMC Gastroenterology 2022 22:288
  17. For patients taking esophagogastroduodenoscopy (EGD), sedation should ideally be used individually based on patients’ comfort and tolerance level. However, currently there is no valid predictive tool. We under...

    Authors: Jinqing Ou, Kuiqing Lu, Junzhen Li, Xi Deng, Junhui He, Guijin Luo, Hongdan Mo, Lingli Lu, Man Yang, Jinqiu Yuan and Pingguang Lei
    Citation: BMC Gastroenterology 2022 22:287
  18. Hepatotoxicity due to highly active antiretroviral therapy (HAART) has gained prominent attention since it can be affected by many factors. The aim of this study was to determine the prevalence of hepatotoxici...

    Authors: Lem Edith Abongwa, Anthony Kebira Nyamache, Fokunang Charles, Judith Torimiro, Nshom Emmanuel, Irénée Domkam, Mbu Eyongetah, Beriyuy Jude, Fung Holgar Mua, Sama Bella, Tankou Colman Tamboh, Erna Charlene Moungang, Victorine Ngum and Paul Okemo
    Citation: BMC Gastroenterology 2022 22:286
  19. Despite numerous reports on ischemic bowel obstruction caused by internal hernia, no case presentation has been reported of an internal hernia caused by a bridge formed between the medial and lateral zones of ...

    Authors: Kohei Kanamori, Takashi Ogimi, Lin Fung Chan, Hiroshi Miyakita, Kazutake Okada, Hajime Kayano, Masaki Mori, Toshio Nakagohri, Kazuo Koyanagi and Seiichiro Yamamoto
    Citation: BMC Gastroenterology 2022 22:285
  20. Endoscopic vacuum therapy (EVT) has become a standard treatment method for esophageal perforations in adults. However, experience with EVT in infants is scarce. In this retrospective case series, we report on ...

    Authors: Dominik J. Kaczmarek, Dominik J. Heling, Christian P. Strassburg, David Katzer, Gesche Düker, Joanna Strohm, Andreas Müller, Andreas Heydweiller and Tobias J. Weismüller
    Citation: BMC Gastroenterology 2022 22:282
  21. Fatigue is one of the most common symptoms reported by patients with ulcerative colitis (UC), while it has not been fully recognized and taken seriously in clinical practice. We aimed to investigate the preval...

    Authors: Feng Xu, Jingyi Hu, Qian Yang, Yuejin Ji, Cheng Cheng, Lei Zhu and Hong Shen
    Citation: BMC Gastroenterology 2022 22:281
  22. Pancreatic body tail carcinoma (PBTC) is a relatively few pancreatic cancer in clinical practice, and its specific clinicopathological features and prognosis have not been fully described. In this study, we ai...

    Authors: Huaqing Shi, Zhou Chen, Shi Dong, Ru He, Yan Du, Zishun Qin and Wence Zhou
    Citation: BMC Gastroenterology 2022 22:279
  23. We previously reported that two differentially methylated region (DMR) networks identified by DMR and co-methylation analyses are strongly correlated with the fibrosis stages of nonalcoholic fatty liver diseas...

    Authors: Suguru Kurokawa, Masato Yoneda, Yuji Ogawa, Yasushi Honda, Takaomi Kessoku, Kento Imajo, Satoru Saito, Atsushi Nakajima and Kikuko Hotta
    Citation: BMC Gastroenterology 2022 22:278
  24. Acute esophageal necrosis (AEN), commonly referred to as Gurvits syndrome or “black esophagus”, is a rare clinical disease. We present a case of AEN associated with diabetic ketoacidosis (DKA).

    Authors: Daisuke Kitawaki, Atsushi Nishida, Keitaro Sakai, Yuji Owaki, Kyohei Nishino, Yoshika Noda and Hirotsugu Imaeda
    Citation: BMC Gastroenterology 2022 22:277
  25. Underwater endoscopic mucosal resection (UMER) is a new method of endoscopic resection to completely remove the lesion without submucosal injection. But few attempts have been carried out for rectal neuroendoc...

    Authors: Haitao Shi, Chuying Wang, Jie Wu, Bin Qin, Jiong Jiang, Na Liu, Yahua Song, Yun Qin and Shiyang Ma
    Citation: BMC Gastroenterology 2022 22:276
  26. Patients with hepatocellular carcinoma (HCC) and macrovascular invasion (MVI) who receive systemic chemotherapy have a poor prognosis. This study aimed to determine if one-shot cisplatin (CDDP) chemotherapy vi...

    Authors: Kensuke Naruto, Tomokazu Kawaoka, Kenichiro Kodama, Yutaro Ogawa, Kei Amioka, Yuki Yoshikawa, Chihiro Kikukawa, Yousuke Suehiro, Kenji Yamaoka, Yuwa Ando, Yumi Kosaka, Shinsuke Uchikawa, Takashi Nakahara, Eisuke Murakami, Atsushi Ono, Takuro Uchida…
    Citation: BMC Gastroenterology 2022 22:275
  27. Previous studies have shown that tumor size has an impact on the prognosis of hepatocellular carcinoma (HCC). Whether tumor size is related to the prognosis of distant metastatic HCC is unclear. The purpose of...

    Authors: Jun Xie, Chunyao Zheng, Jinliang Xie, Fangfei Wang, Dingwei Liu, Rong Zeng, Chensong Yu and Sihai Chen
    Citation: BMC Gastroenterology 2022 22:274

    The Correction to this article has been published in BMC Gastroenterology 2022 22:396

  28. I-125 seeds brachytherapy (ISB) has been used to improve the clinical effectiveness of transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). We aim to appraise the safety and clinical effi...

    Authors: Fu-Lei Gao, Yong Wang, Xiang-Zhong Huang, Tian-Fan Pan and Jin-He Guo
    Citation: BMC Gastroenterology 2022 22:273
  29. Pneumatosis intestinalis (PI) is a rare condition characterized by gas collection in the intestinal wall. We aimed to determine the etiology and affected segments associated with complications, treatment, and ...

    Authors: Naoki Ohmiya, Ichiro Hirata, Hirotsugu Sakamoto, Toshifumi Morishita, Eiko Saito, Katsuyoshi Matsuoka, Tadanobu Nagaya, Shinji Nagata, Miyuki Mukae, Koji Sano, Takayoshi Suzuki, Ken-ichi Tarumi, Seiji Shimizu, Kousaku Kawashima and Toshifumi Hibi
    Citation: BMC Gastroenterology 2022 22:272
  30. Nafamostat mesilate decreases the incidence of pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). However, no studies have administered nafamostat mesilate after ERCP. So we investigated...

    Authors: Joo Seong Kim, Sang Hyub Lee, Namyoung Park, Gunn Huh, Jung Won Chun, Jin Ho Choi, In Rae Cho, Woo Hyun Paik, Ji Kon Ryu and Yong-Tae Kim
    Citation: BMC Gastroenterology 2022 22:271
  31. Serum hepatitis B surface antigen (HBsAg) is a component of both hepatitis B virus (HBV) virions and non-infectious subviral particles (SVPs). Recently, O-glycosylation of the PreS2 domain of middle HBsAg protein...

    Authors: Ayato Murata, Kiyohiko Angata, Maki Sogabe, Shunsuke Sato, Takafumi Ichida, Hisashi Narimatsu and Takuya Genda
    Citation: BMC Gastroenterology 2022 22:270
  32. Intrahepatic cholangiocarcinoma (ICC) is the second most common primary hepatic malignancy with poor prognosis. Intrahepatic bile duct stone (IBDS) is one of the key causes to ICC occurrence and can increase m...

    Authors: Jun Li, Jiongjiong Lu, Shaodong Lv, Shujun Sun, Caifeng Liu, Feng Xu, Haiying Sun, Jiamei Yang, Xinjun Wang, Xingyang Zhong and Junhua Lu
    Citation: BMC Gastroenterology 2022 22:269
  33. Anti-TNF therapy represented a landmark in medical treatment of ulcerative colitis (UC). There is lack of data on the efficacy and safety of these agents in Brazilian patients. The present study aimed to analy...

    Authors: Ligia Yukie Sassaki, Daniela Oliveira Magro, Rogerio Saad-Hossne, Julio Pinheiro Baima, Cristina Flores, Lucianna Motta Correia, Lívia Medeiros Soares Celani, Maria De Lourdes De Abreu Ferrari, Patricia Zacharias, Marley Ribeiro Feitosa, Carlos Henrique Marques Dos Santos, Manoel Alvaro De Freitas Lins Neto, Abel Botelho Quaresma, Sergio Figueiredo De Lima Junior, Graciana Bandeira Salgado De Vasconcelos, Ornella Sari Cassol…
    Citation: BMC Gastroenterology 2022 22:268
  34. Potential dietary inflammation can precursor chronic diseases such as hepatic disorders. We aimed to examine the association of empirical dietary inflammatory patterns (EDIP) and dietary inflammation scores (D...

    Authors: Hossein Farhadnejad, Asal Neshatbini Tehrani, Mitra Kazemi Jahromi, Farshad Teymoori, Ebrahim Mokhtari, Ammar Salehi-Sahlabadi and Parvin Mirmiran
    Citation: BMC Gastroenterology 2022 22:267
  35. Fatty liver index (FLI) is the most recognized blood biomarker for diagnosis of hepatic steatosis (HS), but lacks the reliable specific cut-off points (COPs). Therefore, we aim to investigate the population-sp...

    Authors: Juan Wu, Shen Tian, Hao Li, Zhou Xu, Shu Li, Yu-ling Chen, Xin-yu Liang, Jun Xiao, Jing-yu Song, Rui-ling She, Chen-yu Ma, Jun-han Feng, Zhao-xing Li, Zhi-yu Jiang, Zi-wei Zhang, Kai-nan Wu…
    Citation: BMC Gastroenterology 2022 22:265
  36. The use of ROSE in EUS-FNA pancreatic lesions is still controversial in many centers. In this study, we aimed to demonstrate the contribution of ROSE to the diagnostic accuracy, as well as its assistance to th...

    Authors: Irem Guvendir, Itir Ebru Zemheri and Kamil Ozdil
    Citation: BMC Gastroenterology 2022 22:264
  37. The frequency and intensity of natural disasters are increasing worldwide, which makes our understanding of disaster-related diseases more important than ever. Natural disasters cause mental stress and infecti...

    Authors: Yuji Okazaki, Shuhei Yoshida, Saori Kashima, Daisuke Miyamori and Masatoshi Matsumoto
    Citation: BMC Gastroenterology 2022 22:263
  38. Diverticulosis of the appendix is an uncommon clinical entity, and a preoperative diagnosis is often difficult. Herein we report an unusual case of appendiceal diverticulosis.

    Authors: Toshihisa Kimura, Takanori Goi, Yuki Kidoguchi, Kenji Ohnishi, Tamotsu Togawa, Atsushi Iida and Yasunori Sato
    Citation: BMC Gastroenterology 2022 22:262
  39. Systemic inflammatory response (SIR) plays a crucial role in every step of tumorigenesis and development. More recently, the fibrinogen-to-albumin ratio (FAR), an inflammation-based model, was suggested as a p...

    Authors: Rong-yun Mai, Tao Bai, Xiao-ling Luo and Guo-bin Wu
    Citation: BMC Gastroenterology 2022 22:261
  40. There is a clinical need to develop biomarkers of small bowel damage in coeliac disease and Crohn’s disease. This study evaluated intestinal fatty acid binding protein (iFABP), a potential biomarker of small b...

    Authors: Michael Logan, Mary MacKinder, Clare Martha Clark, Aikaterini Kountouri, Mwansa Jere, Umer Zeeshan Ijaz, Richard Hansen, Paraic McGrogan, Richard K. Russell and Konstantinos Gerasimidis
    Citation: BMC Gastroenterology 2022 22:260
  41. Endocytoscopy (ECS) enables microscopic observation in vivo for the gastrointestinal mucosa; however, there has been no prospective study in which the diagnostic accuracy of ECS for lesions that have not yet u...

    Authors: Yoshihiko Shimoda, Yuichi Shimizu, Hiroaki Takahashi, Satoshi Okahara, Takakazu Miyake, Shin Ichihara, Ikko Tanaka, Masaki Inoue, Sayoko Kinowaki, Masayoshi Ono, Keiko Yamamoto, Shoko Ono and Naoya Sakamoto
    Citation: BMC Gastroenterology 2022 22:259
  42. Colon capsule endoscopy (CCE) is a non-invasive alternative to colonoscopy. The reported sensitivity and specificity of CCE for the detection of clinically significant colonic neoplasia is high. To date, there...

    Authors: C. MacLeod, R. Oliphant, J. G. Docherty and A. J. M. Watson
    Citation: BMC Gastroenterology 2022 22:258
  43. Metallic stents placed in the descending duodenum can cause compression of the major duodenal papilla, resulting in biliary obstruction and pancreatitis. These are notable early adverse events of duodenal sten...

    Authors: Junichi Kaneko, Hirotoshi Ishiwatari, Koiku Asakura, Tatsunori Satoh, Junya Sato, Kazuma Ishikawa, Hiroyuki Matsubayashi, Yohei Yabuuchi, Yoshihiro Kishida, Masao Yoshida, Sayo Ito, Noboru Kawata, Kenichiro Imai, Kohei Takizawa, Kinichi Hotta and Hiroyuki Ono
    Citation: BMC Gastroenterology 2022 22:257
  44. Guidelines on colorectal cancer (CRC) screening recommend screening of average-risk adults only. In addition, screening of individuals with active inflammatory bowel disease (IBD) might result in too many fals...

    Authors: Pernille Thordal Larsen, Susanne Fogh Jørgensen and Sisse Helle Njor
    Citation: BMC Gastroenterology 2022 22:256
  45. For patients with gastro-oesophageal reflux symptoms, the preferred treatment is proton pump inhibitor (PPI) administration for approximately 8 weeks. However, long-term use of PPIs can cause gut microbiome (G...

    Authors: Wenjun Liu, Yong Xie, Yingmeng Li, Longjin Zheng, Qiuping Xiao, Xu Zhou, Qiong Li, Ni Yang, Kexuan Zuo, Tielong Xu, Nong-Hua Lu and Heping Zhang
    Citation: BMC Gastroenterology 2022 22:255

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