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  1. Content type: Research article

    Gastric cancer (GC) has a poor prognosis with wide variation in survival rates across the world. Several studies have shown premalignant lesions gastric atrophy (GA) and intestinal metaplasia (IM) influence ga...

    Authors: Andrew D. Spence, Chris R. Cardwell, Úna C. McMenamin, Blanaid M. Hicks, Brian T. Johnston, Liam J. Murray and Helen G. Coleman

    Citation: BMC Gastroenterology 2017 17:157

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  2. Content type: Research article

    The only treatment for celiac disease (CeD) is a lifelong gluten-free diet (GFD). The restrictive nature of the GFD makes adherence a challenge. As an integral part of CeD management, multiple professional org...

    Authors: Jacob J. Hughey, Bonnie K. Ray, Anne R. Lee, Kristin N. Voorhees, Ciaran P. Kelly and Detlef Schuppan

    Citation: BMC Gastroenterology 2017 17:156

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  3. Content type: Research article

    Gallbladder disease (GBD) is a highly prevalent condition; however, little is known about potential differences in risk factors by sex and ethnicity/race. Our aim was to evaluate dietary, reproductive and obes...

    Authors: Jane C. Figueiredo, Christopher Haiman, Jacqueline Porcel, James Buxbaum, Daniel Stram, Neal Tambe, Wendy Cozen, Lynne Wilkens, Loic Le Marchand and Veronica Wendy Setiawan

    Citation: BMC Gastroenterology 2017 17:153

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  4. Content type: Research article

    Non-alcoholic fatty liver disease (NAFLD) has been recently identified as a risk factor of gastrointestinal tract cancers, especially hepatocellular carcinoma, and colorectal cancer. Whether NAFLD is a risk fa...

    Authors: Nicha Wongjarupong, Buravej Assavapongpaiboon, Paweena Susantitaphong, Wisit Cheungpasitporn, Sombat Treeprasertsuk, Rungsun Rerknimitr and Roongruedee Chaiteerakij

    Citation: BMC Gastroenterology 2017 17:149

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  5. Content type: Research article

    Irritable bowel syndrome (IBS) is a common functional disease of the gastrointestinal tract. The current study aimed to examine the association between visceral hypersensitivity in IBS and cortical activation ...

    Authors: Danping Wang, Xie Zhang, Xuesong Zhang, Zhigang Huang and Yufei Song

    Citation: BMC Gastroenterology 2017 17:148

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  6. Content type: Case report

    Familial adenomatous polyposis (FAP) is a rare, autosomal dominant disease clinically characterized by the early onset of many adenomatous polyps throughout the colon, which turn into colon cancer, if left unt...

    Authors: Flaminia Purchiaroni, Takeshi Nakajima, Taku Sakamoto, Seiichiro Abe and Yutaka Saito

    Citation: BMC Gastroenterology 2017 17:152

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  7. Content type: Technical advance

    Infected pancreatic necrosis (IPN) is a serious local complication of acute pancreatitis, with high mortality. Minimally invasive therapy including percutaneous catheter drainage (PCD) has become the preferred...

    Authors: Pi Liu, Jun Song, Hua-jing Ke, Nong-hua Lv, Yin Zhu, Hao Zeng, Yong Zhu, Liang Xia, Wen-hua He, Ji Li, Xin Huang and Yu-peng Lei

    Citation: BMC Gastroenterology 2017 17:155

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  8. Content type: Research article

    The serum gradient of hepatitis B surface antigen (HBsAg) varies over time after cessation of nucleos(t)ide analog (NA) treatment in patients with chronic hepatitis B (CHB). The association between the time-va...

    Authors: Nai-Hsuan Chien, Yen-Tsung Huang, Chun-Ying Wu, Chi-Yang Chang, Ming-Shiang Wu, Jia-Horng Kao, Lein-Ray Mo, Chi-Ming Tai, Chih-Wen Lin, Tzeng-Huey Yang, Jaw-Town Lin and Yao-Chun Hsu

    Citation: BMC Gastroenterology 2017 17:154

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  9. Content type: Case report

    Esophageal basaloid squamous cell carcinoma (EBSCC) is a rare malignant disease. Advanced EBSCC (AEBSCC) has a poorer prognosis than the more common esophageal squamous cell carcinoma, but no treatment policy ...

    Authors: Toshiya Maebayashi, Naoya Ishibashi, Takuya Aizawa, Masakuni Sakaguchi, Homma Taku, Moritaka Ohhara, Toshirou Takimoto and Yoshiaki Tanaka

    Citation: BMC Gastroenterology 2017 17:151

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  10. Content type: Research article

    Blue laser imaging (BLI) and linked color imaging (LCI) are the color enhancement features of the LASEREO endoscopic system, which provide a narrow band light observation function and expansion and reduction o...

    Authors: Yoshikazu Yoshifuku, Yoji Sanomura, Shiro Oka, Mio Kurihara, Takeshi Mizumoto, Tomohiro Miwata, Yuji Urabe, Toru Hiyama, Shinji Tanaka and Kazuaki Chayama

    Citation: BMC Gastroenterology 2017 17:150

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  11. Content type: Research article

    Although Helicobacter-induced gastric inflammation is the major predisposing factor for gastric carcinogenesis, the precise mechanism by which chronic gastritis causes gastric cancer remains unclear. Intestinal a...

    Authors: Wataru Shibata, Soichiro Sue, Sachiko Tsumura, Yasuaki Ishii, Takeshi Sato, Eri Kameta, Makoto Sugimori, Hiroaki Yamada, Hiroaki Kaneko, Tomohiko Sasaki, Tomohiro Ishii, Toshihide Tamura, Masaaki Kondo and Shin Maeda

    Citation: BMC Gastroenterology 2017 17:145

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    The Correction to this article has been published in BMC Gastroenterology 2018 18:4

  12. Content type: Case report

    Pancreatic hamartomas are extremely rare and may be misdiagnosed as malignant tumors. We report herein a case of a small, solid-type pancreatic hamartoma.

    Authors: Hiroaki Nagano, Masayuki Nakajo, Yoshihiko Fukukura, Yoriko Kajiya, Atsushi Tani, Sadao Tanaka, Mari Toyota, Toru Niihara, Masaki Kitazono, Toyokuni Suenaga and Takashi Yoshiura

    Citation: BMC Gastroenterology 2017 17:146

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  13. Content type: Research article

    Pancreatic cancer occurs more frequently in older patients, but these are underrepresented in the phase III clinical studies that established the current treatment standards. This leads to uncertainty regardin...

    Authors: Anne Katrin Berger, Georg Martin Haag, Martin Ehmann, Anne Byl, Dirk Jäger and Christoph Springfeld

    Citation: BMC Gastroenterology 2017 17:143

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  14. Content type: Case report

    Portal vein embolization is essential for patients with biliary cancer who undergo extended hepatectomy to induce hypertrophy of the future remnant liver. Over 830 patients have undergone the portal vein embol...

    Authors: Chun-Yi Tsai, Motoi Nojiri, Yukihiro Yokoyama, Tomoki Ebata, Takashi Mizuno and Masato Nagino

    Citation: BMC Gastroenterology 2017 17:144

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  15. Content type: Research article

    The prognosis of a gastrointestinal stromal tumor (GIST) is influenced by its anatomic site; however, few studies on the prognosis of gastric GISTs have been reported. The aims of this study were to evaluate l...

    Authors: Chul Hong Park, Gwang Ha Kim, Bong Eun Lee, Geun Am Song, Do Youn Park, Kyung Un Choi, Dae Hwan Kim and Tae Yong Jeon

    Citation: BMC Gastroenterology 2017 17:141

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  16. Content type: Research article

    Alpha-fetoprotein (AFP) is a biomarker for hepatocellular carcinoma (HCC). The significance of pre-treatment AFP (pt-AFP) in non-viral HCC (nvHCC) is not clear.

    Authors: Siriwardana Rohan Chaminda, Thilakarathne Suchintha, Niriella Madunil Anuk, Dassanayake Anuradha Supun, Gunathilake Mahen Bhagya, Liyanage Chandika Anuruddha Habarakada and De Silva Hithadurage Janaka

    Citation: BMC Gastroenterology 2017 17:142

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  17. Content type: Research article

    Gastric cancer is a frequent malignant tumor worldwide and its early detection is crucial for curing the disease and enhancing patients’ survival rate. This study aimed to assess whether the multi-disciplinary...

    Authors: Lianjun Di, Huichao Wu, Rong Zhu, Youfeng Li, Xinglong Wu, Rui Xie, Hongping Li, Haibo Wang, Hua Zhang, Hong Xiao, Hui Chen, Hong Zhen, Kui Zhao, Xuefeng Yang, Ming Xie and Bigung Tuo

    Citation: BMC Gastroenterology 2017 17:147

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  18. Content type: Research article

    Currently, a suitable questionnaire in German language is not available to monitor the progression and evaluate the severity of irritable bowel syndrome (IBS). Therefore, this study aimed to translate the Gast...

    Authors: Sarah K. Schäfer, Kathrin Julia Weidner, Jorge Hoppner, Nicolas Becker, Dana Friedrich, Caroline S. Stokes, Frank Lammert and Volker Köllner

    Citation: BMC Gastroenterology 2017 17:139

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  19. Content type: Research article

    The current clinical practice on chronic hepatitis B (CHB) requires better on-treatment monitoring of viral persistence. Quantified assays for hepatitis B surface antigen (HBsAg) and core-related antigen (HBcr...

    Authors: Zhan-Qing Zhang, Xiao-Nan Zhang, Wei Lu, Yan-Bing Wang, Qi-Cheng Weng and Yan-Ling Feng

    Citation: BMC Gastroenterology 2017 17:140

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  20. Content type: Research article

    Real-life data on inflammatory bowel disease (IBD) prevalence and costs are scarce. The aims of this study were to provide an overview of the prevalence, mortality, health care utilization and costs of IBD pat...

    Authors: Caroline Bähler, Stephan R. Vavricka, Alain M. Schoepfer, Beat Brüngger and Oliver Reich

    Citation: BMC Gastroenterology 2017 17:138

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  21. Content type: Research article

    Very few studies report on the prevalence of irritable bowel syndrome (IBS) and its correlates in the Middle East. This study investigated Irritable Bowel Syndrome (IBS) prevalence in a sample of Lebanese adul...

    Authors: Rajaa Chatila, Mahmoud Merhi, Essa Hariri, Nada Sabbah and Mary E. Deeb

    Citation: BMC Gastroenterology 2017 17:137

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  22. Content type: Research article

    The gut microbiota plays crucial roles in the development of non-alcoholic steatohepatitis (NASH). However, the precise mechanisms by which alterations of the gut microbiota and its metabolism contributing to ...

    Authors: Shoji Yamada, Nobuhiko Kamada, Takeru Amiya, Nobuhiro Nakamoto, Toshiaki Nakaoka, Masaki Kimura, Yoshimasa Saito, Chieko Ejima, Takanori Kanai and Hidetsugu Saito

    Citation: BMC Gastroenterology 2017 17:136

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  23. Content type: Research article

    Nonalcoholic fatty liver disease (NAFLD) is a common problem across the world. We aimed to determine the prevalence of NAFLD and its associations in Sri Lankan adolescents living in an urban Sri Lankan community.

    Authors: Shaman Rajindrajith, Arunasalam Pathmeswaran, Chamilka Jayasinghe, Dulani Kottahachchi, Anuradhani Kasturiratne, Shamila T. de Silva, Madunil A. Niriella, Anuradha S. Dassanayake, Arjuna P. de Silva and H. Janaka de Silva

    Citation: BMC Gastroenterology 2017 17:135

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  24. Content type: Research article

    Gut microbiota may be altered in patients with cirrhosis, and may further change after administration of lactulose. We studied the composition of gut microbiota in patients with cirrhosis and assessed the effe...

    Authors: Aditya Narayan Sarangi, Amit Goel, Ankur Singh, Avani Sasi and Rakesh Aggarwal

    Citation: BMC Gastroenterology 2017 17:125

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  25. Content type: Research article

    Hypovitaminosis D is associated with many features of the metabolic syndrome, including non-alcoholic fatty liver disease. Vitamin D-enriched mushrooms extracts exert a synergistic anti-inflammatory effect. Th...

    Authors: A. Drori, D. Rotnemer-Golinkin, S. Avni, A. Drori, O. Danay, D. Levanon, J. Tam, L. Zolotarev and Y. Ilan

    Citation: BMC Gastroenterology 2017 17:130

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  26. Content type: Debate

    During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequ...

    Authors: Frederick Verbeke, Yorick Janssens, Evelien Wynendaele and Bart De Spiegeleer

    Citation: BMC Gastroenterology 2017 17:128

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  27. Content type: Research article

    Gastro-esophageal reflux disease (GERD) is suggested to be associated with some socio-demographic and lifestyle factors. Although the roles of some factors such as obesity are well documented, evidence on the ...

    Authors: Omid Eslami, Mansour Shahraki, Ali Bahari and Touran Shahraki

    Citation: BMC Gastroenterology 2017 17:132

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  28. Content type: Research article

    Liver stiffness measurement (LSM) has recently become available for assessment of liver fibrosis. We aimed to develop a prediction model for liver fibrosis using clinical variables, including LSM.

    Authors: Yusuke Mitsuka, Yutaka Midorikawa, Hayato Abe, Naoki Matsumoto, Mitsuhiko Moriyama, Hiroki Haradome, Masahiko Sugitani, Shingo Tsuji and Tadatoshi Takayama

    Citation: BMC Gastroenterology 2017 17:133

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  29. Content type: Research article

    Acetaminophen (APAP) is a readily available and safe painkiller. However, its overdose is the most common cause of acute liver injury (ALI). Many predisposing factors contribute to susceptibility to APAP-induc...

    Authors: Tae Hyung Kim, Dahee Choi, Joo Young Kim, Jeong Hyeon Lee and Seung-Hoi Koo

    Citation: BMC Gastroenterology 2017 17:124

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  31. Content type: Case report

    Post-transplant tuberculosis (PTTB) is a serious opportunistic infection in renal graft recipients with a 30-70 fold higher incidence compared to the general population. PTTB occurs most frequently within the ...

    Authors: Andrea Cikova, Diana Vavrincova-Yaghi, Peter Vavrinec, Anna Dobisova, Andrea Gebhardtova, Zora Flassikova, Mark A. Seelen, Robert H. Henning and Aktham Yaghi

    Citation: BMC Gastroenterology 2017 17:131

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  32. Content type: Research article

    The present study was performed to compare the safety of sedation during endoscopic submucosal dissection (ESD) in the endoscopy room versus operation room.

    Authors: Daisuke Yamaguchi, Naoko Yamaguchi, Yuki Takeuchi, Takahiro Yukimoto, Kei Ikeda, Kosuke Matsumoto, Rikako Kinoshita, Saori Kamachi, Kyosuke Sugiyama, Tomohito Morisaki, Keisuke Ario, Hisako Yoshida, Ryo Katsuki, Seiji Tsunada and Kazuma Fujimoto

    Citation: BMC Gastroenterology 2017 17:127

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  33. Content type: Research article

    Additional surgery is recommended when early colorectal cancer (ECRC) is resected by non-curative endoscopic submucosal dissection (ESD) and there is significant risk of lymph node metastasis (LNM). The aim of...

    Authors: Tao Chen, Yi-Qun Zhang, Wei-Feng Chen, Ying-Yong Hou, Li-Qing Yao, Yun-Shi Zhong, Mei-Dong Xu and Ping-Hong Zhou

    Citation: BMC Gastroenterology 2017 17:134

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  34. Content type: Case report

    Hepatobiliary tuberculosis includes miliary, tuberculous hepatitis or localized forms. The localised form is extremely uncommon and can mimic malignancy. Still rarer is its presentation as sclerosing cholangitis.

    Authors: Aleena Jain, Rachana Chaturvedi, Chetan Kantharia, Amita Joshi, Mangesh Londhe and Mayura Kekan

    Citation: BMC Gastroenterology 2017 17:126

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  35. Content type: Research article

    Chronic hepatitis C virus (HCV) infection is associated with impairment of cognitive function and mood disorders. Our aim was to evaluate the impact of sustained virological response (SVR) on cognitive functio...

    Authors: Mary Ellen Dias Barbosa, Ana Luiza Zaninotto, Daniel Ferraz de Campos Mazo, Mario Guimarães Pessoa, Cláudia Pinto Marques Souza de Oliveira, Flair José Carrilho and Alberto Queiroz Farias

    Citation: BMC Gastroenterology 2017 17:122

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  36. Content type: Research article

    Functional dyspepsia (FD) is a gastrointestinal disorder characterized by recurrent and diverse symptoms and pathophysiology that remains unexplained following routine clinical investigation. Enzynorm®f is a phar...

    Authors: Kristin Forssmann, Larissa Meier, Bernhard Uehleke, Cornelia Breuer and Rainer Stange

    Citation: BMC Gastroenterology 2017 17:123

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  37. Content type: Research article

    Eradication of hepatitis C virus (HCV) using direct-acting agents (DAA) has been associated with a financial burden to health authorities worldwide. We aimed to evaluate the guideline-based treatment costs by ...

    Authors: Hugo Perazzo, Marcelino Jose Jorge, Julio Castro Silva, Alexandre Monken Avellar, Patrícia Santos Silva, Carmen Romero, Valdilea Gonçalves Veloso, Ruben Mujica-Mota, Rob Anderson, Chris Hyde and Rodolfo Castro

    Citation: BMC Gastroenterology 2017 17:119

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  38. Content type: Research article

    Minimally invasive pancreatoduodenectomy (MIPD) has been gradually attempted. However, whether MIPD is superior, equal or inferior to its conventional open pancreatoduodenectomy (OPD) is not clear.

    Authors: Ke Chen, Yu Pan, Xiao-long Liu, Guang-yi Jiang, Di Wu, Hendi Maher and Xiu-jun Cai

    Citation: BMC Gastroenterology 2017 17:120

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  39. Content type: Research article

    In metastatic colorectal cancer, the location of the primary tumor has been suggested to have biological significance. In this study, we investigated whether primary tumor location affects cetuximab efficacy i...

    Authors: Dalyong Kim, Sun Young Kim, Ji Sung Lee, Yong Sang Hong, Jeong Eun Kim, Kyu-pyo Kim, Jihun Kim, Se Jin Jang, Young-Kwang Yoon and Tae Won Kim

    Citation: BMC Gastroenterology 2017 17:121

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  40. Content type: Research article

    The anatomy of esophagogastric junction (EGJ) serves as the anti-reflux barrier. The gastroesophageal flap valve (GEFV) is a component of EGJ. The aim of the current study was to assess its correlation with th...

    Authors: Chenxi Xie, Yuwen Li, Ning Zhang, Lishou Xiong, Minhu Chen and Yinglian Xiao

    Citation: BMC Gastroenterology 2017 17:118

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  42. Content type: Correction

    After publication of the original article [1], it was noticed that one of the affiliations of author Carmine Vecchione was missing.

    Authors: Marcello Persico, Mario Masarone, Antonio Damato, Mariateresa Ambrosio, Alessandro Federico, Valerio Rosato, Tommaso Bucci, Albino Carrizzo and Carmine Vecchione

    Citation: BMC Gastroenterology 2017 17:116

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    The original article was published in BMC Gastroenterology 2017 17:35

  43. Content type: Research article

    In clinical practice, assessment of constipation depends on reliability, consistency and frequency of several commonly reported or core symptoms. It is not known if frequency patterns of constipation symptoms ...

    Authors: Abdul Wahab Patimah, Yeong Yeh Lee and Mohd Yusoff Dariah

    Citation: BMC Gastroenterology 2017 17:115

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  44. Content type: Research article

    Patients could develop endocrine and exocrine pancreatic insufficiency after acute pancreatitis (AP), but the morbidity, risk factors and outcome remain unclear. The aim of the present study was to evaluate th...

    Authors: Jianfeng Tu, Jingzhu Zhang, Lu Ke, Yue Yang, Qi Yang, Guotao Lu, Baiqiang Li, Zhihui Tong, Weiqin Li and Jieshou Li

    Citation: BMC Gastroenterology 2017 17:114

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  45. Content type: Research article

    Approximately 60% of patients presenting to dentists with erosive tooth wear have significant gastroesophageal reflux (GERD), despite minor reflux symptoms. No longitudinal studies of reflux-associated erosive...

    Authors: Clive H. Wilder-Smith, Andrea Materna, Lukas Martig and Adrian Lussi

    Citation: BMC Gastroenterology 2017 17:113

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  46. Content type: Research article

    Tumor suppressor gene p53 expression has been reported in patients with ulcerative colitis (UC). However, the correlation between p53 expression and UC remains controversial. The aim of this meta-analysis was ...

    Authors: Xiaohong Lu, Yuanjie Yu and Shiyun Tan

    Citation: BMC Gastroenterology 2017 17:111

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  47. Content type: Research article

    Portal vein thrombosis (PVT) is a serious complication in liver cirrhosis with portal hypertension. We examined the treatment, recurrence and prognosis of PVT in cirrhotic patients.

    Authors: Shunichiro Fujiyama, Satoshi Saitoh, Yusuke Kawamura, Hitomi Sezaki, Tetsuya Hosaka, Norio Akuta, Masahiro Kobayashi, Yoshiyuki Suzuki, Fumitaka Suzuki, Yasuji Arase, Kenji Ikeda and Hiromitsu Kumada

    Citation: BMC Gastroenterology 2017 17:112

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  48. Content type: Research article

    Globus pharyngeus is common and has a low cure rate. Its etiology is complex and reported to be associated with laryngopharyngeal reflux (LPR). However, some patients with globus do not exhibit any reflux symp...

    Authors: Heyan Ding, Zhijun Duan, Dong Yang, Zhifeng Zhang, Lixia Wang, Xiaoyu Sun, Yiwen Yao, Xue Lin, Hang Yang, Shan Wang and Jiande D. Z. Chen

    Citation: BMC Gastroenterology 2017 17:109

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  49. Content type: Research article

    We aimed to evaluate the role of fecal calprotectin (FC) as a noninvasive marker for the disease activity of ulcerative colitis (UC) in a Korean cohort.

    Authors: Sun-Ho Lee, Min-Ju Kim, Kiju Chang, Eun Mi Song, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kyung-Jo Kim, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang and Byong Duk Ye

    Citation: BMC Gastroenterology 2017 17:110

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  50. Content type: Technical advance

    Prophylactic pancreatic stents after endoscopic retrograde cholangiopancreatography (ERCP) can help prevent post-ERCP pancreatitis. However most of the pancreatic stents need to be removed by another ERCP. The...

    Authors: Cheng Zhang, Yu-long Yang, Yue-feng Ma, Hong-wei Zhang, Jing-yi Li, Mei-ju Lin, Li-jun Shi and Chun-chun Qi

    Citation: BMC Gastroenterology 2017 17:108

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