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  1. Aortoenteric fistula (AEF) is a rare cause of gastrointestinal bleeding and is often misdiagnosed in clinical practice. Herein, a case series of AEFs are presented and the clinical characteristics, diagnosis, ...

    Authors: Jia Luo, Wen Tang, Mengran Wang, Yao Xiao, Manhong Tan and Chunyan Jiang
    Citation: BMC Gastroenterology 2021 21:49
  2. Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disease characterized by chronic abdominal discomfort and pain. The mechanisms of abdominal pain, as a relevant symptom, in IBS are...

    Authors: Zhongyuan Lin, Yimin Wang, Shiqing Lin, Decheng Liu, Guohui Mo, Hui Zhang and Yunling Dou
    Citation: BMC Gastroenterology 2021 21:48
  3. Aorto-esophageal fistula (AEF) caused by foreign bodies ingestion is a rare but devastating disorder. Thoracic endovascular aortic repair (TEVAR) has become a widely accepted intervention for treating aorto-es...

    Authors: Yu-Yan Zhang, Shan Li, Xiang-Lei Yuan and Bing Hu
    Citation: BMC Gastroenterology 2021 21:46
  4. Upper gastrointestinal (GI) bleeding is the most important presentation of an aorto-duodenal fistula (ADF). Early diagnosis is difficult, and the disease is associated with high mortality. The present study ai...

    Authors: Chikamasa Ichita, Akiko Sasaki, Chihiro Sumida, Karen Kimura, Takashi Nishino, Junichi Tasaki, Sakue Masuda, Kazuya Koizumi, Jun Kawachi and Makoto Kako
    Citation: BMC Gastroenterology 2021 21:45
  5. This study evaluates preliminary results of image-guided percutaneous direct pancreatic duct intervention in the management of pancreatic fistula after surgery or pancreatitis when initially ineligible for sur...

    Authors: Xi Li, Ricardo Paz-Fumagalli, Weiping Wang, Beau B. Toskich, John A. Stauffer, Gregory T. Frey, J. Mark McKinney and Justin H. Nguyen
    Citation: BMC Gastroenterology 2021 21:44
  6. A series of evidence revealed that body mass index was an important confounding factor in the research of uric acid and ischemic heart disease/hypertension. The objective of this study was to investigate wheth...

    Authors: Mimi Zhou, Nan Yang, Xin Xing, Danyan Chang, Juan Li, Jiang Deng, Yi Chen, Chunhua Hu, Rou Zhang, Xiaolan Lu, Yingren Zhao and Yingli He
    Citation: BMC Gastroenterology 2021 21:43
  7. Nutrition is a modifiable risk factor that plays an important role in the prevention or delaying of the onset of non-alcoholic fatty liver disease (NAFLD). Previous studies have focused on NAFLD and individual...

    Authors: Ammar Salehi-sahlabadi, Samaneh Sadat, Sara Beigrezaei, Makan Pourmasomi, Awat Feizi, Reza Ghiasvand, Amir Hadi, Cain C. T. Clark and Maryam Miraghajani
    Citation: BMC Gastroenterology 2021 21:41
  8. Gastrointestinal tumor bleeding remains a clinical challenge because it is difficult to treat with conventional endoscopic hemostatic options. Recently, an endoscopic hemostatic powder (UI-EWD) was developed a...

    Authors: Jongbeom Shin, Boram Cha, Jin-Seok Park, Weonjin Ko, Kye Sook Kwon, Jin-Woo Lee, Hyung Kil Kim and Yong Woon Shin
    Citation: BMC Gastroenterology 2021 21:40
  9. A wide variation of causes can lead to gastrointestinal symptoms in children- an infection with parasites is one of them. The expansion of international travel might lead to an increase in testing children for...

    Authors: Corinne Légeret, Céline Rüttimann, Hans Fankhauser and Henrik Köhler
    Citation: BMC Gastroenterology 2021 21:39
  10. Adenocarcinoma in Esophagogastric Junction (AEG) is a severe gastrointestinal malignancy with a unique clinicopathological feature. Hence, we aimed to develop a competing risk nomogram for predicting survival ...

    Authors: Tongbo Wang, Yan Wu, Hong Zhou, Chaorui Wu, Xiaojie Zhang, Yingtai Chen and Dongbing Zhao
    Citation: BMC Gastroenterology 2021 21:38
  11. Irritable bowel syndrome (IBS) is defined as a multifactorial disorder associated with visceral hypersensitivity, altered gut motility and dysfunction of the brain-gut axis. Gut microbiota and its metabolites ...

    Authors: Ilnar F. Shaidullov, Dina M. Sorokina, Farit G. Sitdikov, Anton Hermann, Sayar R. Abdulkhakov and Guzel F. Sitdikova
    Citation: BMC Gastroenterology 2021 21:37
  12. The Korean National Cancer Screening Program has been providing annual fecal immunochemical test for colorectal cancer (CRC) to adults aged 50 years and older since 2004. The Korean Colonoscopy Screening Pilot...

    Authors: Bomi Park, Jae Kwan Jun, Byung Chang Kim, Kui Son Choi and Mina Suh
    Citation: BMC Gastroenterology 2021 21:36
  13. Various serum markers for early identification of severe acute pancreatitis (SAP) have been studied. Serum macrophage migration inhibitory factor (MIF) was reported to be correlated with severity of acute panc...

    Authors: Dingcheng Shen, Caixi Tang, Shuai Zhu and Gengwen Huang
    Citation: BMC Gastroenterology 2021 21:34
  14. Vedolizumab has become a standard treatment for the inflammatory bowel diseases ulcerative colitis (UC) and Crohn’s disease (CD). However, there is an ongoing debate on the ideal individual treatment algorithm...

    Authors: Laura Mühl, Emily Becker, Tanja M. Müller, Raja Atreya, Imke Atreya, Markus F. Neurath and Sebastian Zundler
    Citation: BMC Gastroenterology 2021 21:33
  15. Patients with inflammatory bowel disease (IBD) and intestinal Behçet’s disease (BD) are vulnerable to micronutrient deficiencies due to diarrhea-related gastrointestinal loss and poor dietary intake caused by ...

    Authors: Yong Eun Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, TaeIl Kim and Won Ho Kim
    Citation: BMC Gastroenterology 2021 21:32
  16. Percutaneous Endoscopic Gastrostomy (PEG) can involve some complications, despite the good safety of its track record. The Buried Bumper Syndrome (BBS) is a rare, late and dangerous complication that consists ...

    Authors: A. G. Gravina, A. Tessitore, V. M. Ormando, F. Nagar, M. Romeo, M. R. Amato, M. Dallio, C. Loguercio, A. Federico, M. Romano and F. Ferraro
    Citation: BMC Gastroenterology 2021 21:31
  17. Thrombocytopenia can rapidly improve in chronic hepatitis C (CHC) patients receiving direct-acting antiviral agents (DAA). The role of baseline (BL) thrombopoietin (TPO) in this phenomenon is unclear.

    Authors: Yen-Chun Chen, Ping-Hung Ko, Chi-Che Lee, Chih-Wei Tseng and Kuo-Chih Tseng
    Citation: BMC Gastroenterology 2021 21:30
  18. Mucosal Schwann cell hamartomas are rare neurogenic tumors which present most commonly in the distal colon. They are usually discovered as small, single polyps in asymptomatic patients.

    Authors: Takeshi Okamoto, Takaaki Yoshimoto and Katsuyuki Fukuda
    Citation: BMC Gastroenterology 2021 21:29
  19. Only a few reports have assessed the effectiveness of endoscopic biliary drainage (EBD) in hepatocellular carcinoma (HCC) patients with obstructive jaundice and liver dysfunction.

    Authors: Akihiro Matsumi, Hironari Kato, Toru Ueki, Etsuji Ishida, Masahiro Takatani, Masakuni Fujii, Masaki Wato, Tatsuya Toyokawa, Ryo Harada, Hirofumi Tsugeno, Minoru Matsubara, Hiroshi Matsushita and Hiroyuki Okada
    Citation: BMC Gastroenterology 2021 21:28
  20. Gastritis cystica polyposa (GCP) is a recently recognized entity histologically characterized by hyperplasia and cystic dilatation of the gastric glands spreading through the submucosal layer. Its symptoms inc...

    Authors: Masaaki Yoshikawa, Hiroki Kinoshita, Naoki Nishimura, Rieko Takai, Takuya Matsuda, Satoshi Nakatani, Erika Shioyama, Kosuke Takeda and Hitoshi Yoshiji
    Citation: BMC Gastroenterology 2021 21:27
  21. To evaluate the efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) on hepatic sinusoidal obstruction syndrome (HSOS) associated with consumption of Gynura segetum (GS).

    Authors: Lijie Zhang, Qing Li, Joyman Makamure, Dan Zhao, Ziyi Liu, Chuansheng Zheng and Bin Liang
    Citation: BMC Gastroenterology 2021 21:26
  22. We aimed to determine the prevalence of elevated alanine aminotransferase (eALT) in employees of a German chemical company, and analyze its association with sociodemographic, work- and lifestyle-related factors.

    Authors: Matthias Claus, Christoph Antoni and Bernd Hofmann
    Citation: BMC Gastroenterology 2021 21:25
  23. An intravascular ultrasound catheter (IVUSc) was developed for intracardiac ultrasound to assess interventions with compelling results. However, intrahepatic vascular exploration was rarely tested and was alwa...

    Authors: Takeshi Urade, Juan Manuel Verde, Alain García Vázquez, Konstanze Gunzert, Patrick Pessaux, Jacques Marescaux and Mariano Eduardo Giménez
    Citation: BMC Gastroenterology 2021 21:24
  24. Irritable bowel syndrome (IBS) is a very common functional bowel disorder. However, the difference of depression and anxiety comorbidities among different IBS subtypes is still not well evaluated. This study a...

    Authors: Zhichao Hu, Meixuan Li, Liang Yao, Yinshu Wang, Enkang Wang, Jianye Yuan, Fengyun Wang, Kehu Yang, Zhaoxiang Bian and Linda L. D. Zhong
    Citation: BMC Gastroenterology 2021 21:23
  25. Sedation is commonly used in gastrointestinal endoscopy; however, considerable variability in sedation practices has been reported. The objective of this review was to identify and synthesize existing recommen...

    Authors: Fahima Dossa, Olivia Megetto, Mafo Yakubu, David D. Q. Zhang and Nancy N. Baxter
    Citation: BMC Gastroenterology 2021 21:22
  26. The histological diagnosis of autoimmune pancreatitis (AIP) by an endoscopic ultrasound (EUS)-guided approach is still challenging.

    Authors: Koichiro Tsutsumi, Toru Ueki, Yasuhiro Noma, Kunihiro Omonishi, Kyotaro Ohno, Soichiro Kawahara, Takashi Oda, Hironari Kato and Hiroyuki Okada
    Citation: BMC Gastroenterology 2021 21:21
  27. Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is an infrequent type of primary liver cancer that comprises hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). This study investigat...

    Authors: Chih-Wen Lin, Tsung-Chin Wu, Hung-Yu Lin, Chao-Ming Hung, Pei-Min Hsieh, Jen-Hao Yeh, Pojen Hsiao, Ya-Ling Huang, Yu-Chan Li, Ya-Chin Wang, Chih-Wen Shu and Yaw-Sen Chen
    Citation: BMC Gastroenterology 2021 21:20
  28. Dasatinib is a second-generation tyrosine kinase inhibitor (TKI) developed for treatment of patients with chronic myeloid leukemia (CML). The drug has been shown to act as a potent multikinase inhibitor by blo...

    Authors: Naoki Oshima, Yoshiyuki Mishima, Kotaro Shibagaki, Kousaku Kawashima, Norihisa Ishimura, Fumiyoshi Ikejiri, Chie Onishi, Takahiro Okada, Masaya Inoue, Ichiro Moriyama, Junji Suzumiya, Yoshikazu Kinoshita and Shunji Ishihara
    Citation: BMC Gastroenterology 2021 21:19
  29. Combining upper and lower gastrointestinal tract (GI) approaches allows expansion of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) indications for pelvic lesions. The upper GI approach has been...

    Authors: Naoki Mita, Takuji Iwashita, Akihiko Senju, Hironao Ichikawa, Yuhei Iwasa, Shinya Uemura, Ichiro Yasuda and Masahito Shimizu
    Citation: BMC Gastroenterology 2021 21:18
  30. Impairment of activities of daily living (ADL) due to hemorrhagic gastroduodenal ulcers (HGU) has rarely been evaluated. We analyzed the risk factors of poor prognosis, including mortality and impairment of AD...

    Authors: Junya Arai, Jun Kato, Nobuo Toda, Ken Kurokawa, Chikako Shibata, Shigeyuki Kurosaki, Kazuyoshi Funato, Mayuko Kondo, Kaoru Takagi, Kentaro Kojima, Takamasa Ohki, Michiharu Seki and Kazumi Tagawa
    Citation: BMC Gastroenterology 2021 21:16
  31. The number of positive lymph nodes, which was defined as “N stage”, is mostly used to predict the survival of D2-resected gastric cancer patients, not the location. A “central lymph node” (CnLN) was defined by...

    Authors: Huiwen Lu, Bochao Zhao, Rui Huang, Yimeng Sun, Zirui Zhu, Huimian Xu and Baojun Huang
    Citation: BMC Gastroenterology 2021 21:15
  32. Short-chain fatty acids (SCFAs) and serotonin (5-hydroxytryptamine, 5-HT) may be associated with the pathogenesis of irritable bowel syndrome (IBS). There are some reports of alterations in SCFAs and 5-HT in I...

    Authors: Mei Luo, Xiaojun Zhuang, Zhenyi Tian and Lishou Xiong
    Citation: BMC Gastroenterology 2021 21:14
  33. Many patients with ulcerative colitis (UC) in clinical remission frequently complain of bowel symptoms such as increased stool frequency (SF) and rectal bleeding (RB). However, studies on these patient-reporte...

    Authors: Kwangwoo Nam, Sang Hyoung Park, Jun Ho Oh, Ho-Su Lee, Soomin Noh, Jae Cheol Park, Jin Yong Kim, Eun Hye Oh, Jeongseok Kim, Nam Seok Ham, Sung Wook Hwang, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung and Suk-Kyun Yang
    Citation: BMC Gastroenterology 2021 21:13
  34. Chronic intestinal schistosomiasis has been reported to be associated with colonic polyps, colorectal cancer and ulcerative colitis. We aim to investigate the clinical characteristics of intestinal-related les...

    Authors: Xian Qin, Cai-Yuan Liu, Yi-Lin Xiong, Tao Bai, Lei Zhang, Xiao-Hua Hou and Jun Song
    Citation: BMC Gastroenterology 2021 21:12
  35. Colonic volvulus, a condition in which a colonic segment partially twists around its base, is the third leading cause of large bowel obstruction after colonic neoplasms and diverticular disease. However, volvu...

    Authors: Akihiro Yoshida, Yasutake Uchima, Naoki Hosaka, Kosuke Minaga and Masatoshi Kudo
    Citation: BMC Gastroenterology 2021 21:11
  36. The gold standard for the diagnosis of liver fibrosis and nonalcoholic fatty liver disease (NAFLD) is liver biopsy. Various noninvasive modalities, e.g., ultrasonography, elastography and clinical predictive s...

    Authors: Pakanat Decharatanachart, Roongruedee Chaiteerakij, Thodsawit Tiyarattanachai and Sombat Treeprasertsuk
    Citation: BMC Gastroenterology 2021 21:10
  37. Pancreatic ductal adenocarcinoma (PDAC) rarely metastasizes to the brain; therefore, the features of brain metastasis of PDAC are still unknown. We encountered simultaneous metastases to the brain and lung in ...

    Authors: Yoshito Oka, Shigetsugu Takano, Yusuke Kouchi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Isamu Hosokawa, Takashi Mishima, Takanori Konishi, Takashi Kishimoto and Masayuki Ohtsuka
    Citation: BMC Gastroenterology 2021 21:9
  38. Endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/B) is a standard method for pathological diagnosis of pancreatic solid lesions. The EchoTip ProCore 20G® (PC20), a 20-gauge biopsy needle wit...

    Authors: Shunsuke Watanabe, Jun Miyoshi, Masao Toki, Komei Kambayashi, Shuichi Kitada, Takeshi Nosaka, Tomoyuki Goto, Hirotaka Ota, Kazushige Ochiai, Koichi Gondo, Nobuhito Ikeuchi, Shujiro Tsuji, Kenji Nakamura, Junji Shibahara and Tadakazu Hisamatsu
    Citation: BMC Gastroenterology 2021 21:8
  39. Desmoglein2 (DSG2) is a transmembrane protein that helps regulate intercellular connections and contributes to desmosome assembly. Desmosome are associated with cell adhesion junctions, which play an important...

    Authors: Tingting Yang, Xuan Gu, Lizhou Jia, Jiaojiao Guo, Qi Tang, Jin Zhu, Wei Zhao and Zhenqing Feng
    Citation: BMC Gastroenterology 2021 21:7
  40. Chronic active Epstein–Barr virus infection (CAEBV) is defined as Epstein–Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious...

    Authors: Yosuke Aihara, Kei Moriya, Naotaka Shimozato, Shinsaku Nagamatsu, Shinya Kobayashi, Masakazu Uejima, Hideki Matsuo, Eiwa Ishida, Hideo Yagi, Toshiya Nakatani, Hitoshi Yoshiji and Eiryo Kikuchi
    Citation: BMC Gastroenterology 2021 21:6
  41. Non-celiac gluten or wheat sensitivity (NCWS) is a “clinical entity induced by the ingestion of wheat leading to intestinal and/or extraintestinal symptoms that improve once the wheat-containing foodstuff is r...

    Authors: Consolato Sergi, Vincenzo Villanacci and Antonio Carroccio
    Citation: BMC Gastroenterology 2021 21:5
  42. At present, most assessments of liver fibrosis staging mainly focus on non-invasive diagnostic methods. This study aims to construct a noninvasive model to predict liver histology for antiviral therapy in chro...

    Authors: Shanshan Chen, Haijun Huang and Wei Huang
    Citation: BMC Gastroenterology 2021 21:4

    The Correction to this article has been published in BMC Gastroenterology 2021 21:109

  43. What kind of patients with hypertriglyceridemic acute pancreatitis (HLAP) might benefit from plasmapheresis (PP) remains unknown. The objective of this study is to determine the predict function of total chole...

    Authors: Zhu Chen, Xiaolong Huang, Na Han, Yanxia Guo, Jing Chen, Yaogui Ning and Minwei Zhang
    Citation: BMC Gastroenterology 2021 21:3
  44. Portal hypertension (PH) is the main cause of complications and death in liver cirrhosis. The effect of oral administration of octreotide (OCT), a drug that reduces PH by the constriction of mesenteric arterie...

    Authors: Xiaoyu Sun, Shunxiong Tang, Binbin Hou, Zhijun Duan, Zhen Liu, Yang Li, Shoucheng He, Qiuming Wang and Qingyong Chang
    Citation: BMC Gastroenterology 2021 21:2
  45. The role of platelets on the prognosis of patients with liver transplantation remains unclear. Thus, we aimed to evaluate the influence of preoperative platelet count on postoperative morbidity after liver tra...

    Authors: Qingshan Li, Yue Wang, Tao Ma, Fenggang Ren, Fan Mu, Rongqian Wu, Yi Lv and Bo Wang
    Citation: BMC Gastroenterology 2021 21:1
  46. End-stage liver disease (ESLD) is a major burden on public health, particularly in sub-Saharan Africa, where hepatitis B virus (HBV) is an important risk factor. We aimed to describe clinical characteristics o...

    Authors: Yvonne Ayerki Nartey, Yaw Asante Awuku, Adwoa Agyei-Nkansah, Amoako Duah, Sally Afua Bampoh, Joshua Ayawin, Shadrack Osei Asibey, Niklas K. Björkström, Weimin Ye, Mary Yeboah Afihene, Lewis Rowland Roberts and Amelie Plymoth
    Citation: BMC Gastroenterology 2020 20:428
  47. Treating hernias is one of the oldest challenges in surgery. The gallbladder as content in the case of abdominal hernias has only been reported in a few cases in the current literature. Cholecyst has only been...

    Authors: János Tajti Jr., József Pieler, Szabolcs Ábrahám, Zsolt Simonka, Attila Paszt and György Lázár
    Citation: BMC Gastroenterology 2020 20:425

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