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  1. Content type: Research article

    Transarterial chemoembolization (TACE) is the recommended treatment for hepatocellular carcinoma (HCC) patients at Barcelona Clinic Liver Cancer (BCLC) B-stage, whereas sorafenib is an orally administered smal...

    Authors: Lin Li, Wenzhuo Zhao, Mengmeng Wang, Jie Hu, Enxin Wang, Yan Zhao and Lei Liu

    Citation: BMC Gastroenterology 2018 18:138

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  2. Content type: Case report

    The use of immune-checkpoint inhibitors in cancer treatment has become increasingly common, resulting in an increase in the incidence of related side effects. Diarrhoea and colitis have been previously documen...

    Authors: Ryosuke Yamauchi, Toshihiro Araki, Keiichi Mitsuyama, Takaaki Tokito, Hidenobu Ishii, Shinichiro Yoshioka, Kotaro Kuwaki, Atsushi Mori, Tetsuhiro Yoshimura, Osamu Tsuruta and Takuji Torimura

    Citation: BMC Gastroenterology 2018 18:135

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  3. Content type: Research article

    Successful H. pylori treatment requires the knowledge of local antimicrobial resistance. Data on the efficacy of H. pylori eradication regimens available in sub-Saharan Africa are scant, hence the optimal treatme...

    Authors: Jean Damascene Kabakambira, Celestin Hategeka, Cameron Page, Cyprien Ntirenganya, Vincent Dusabejambo, Jules Ndoli, Francois Ngabonziza, DeVon Hale, Claude Bayingana and Tim Walker

    Citation: BMC Gastroenterology 2018 18:134

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  4. Content type: Research article

    Although many patients still have anxiety about upper gastrointestinal (GI) endoscopy, there have been few reports on the influence of distractions for a person who is going to undergo upper GI endoscopy soon....

    Authors: Masahiro Sogabe, Toshiya Okahisa, Yuka Adachi, Masanori Takehara, Shinichi Hamada, Jun Okazaki, Yasuteru Fujino, Akira Fukuya, Kaizo Kagemoto, Akihiro Hirao, Koichi Okamoto, Masahiko Nakasono and Tetsuji Takayama

    Citation: BMC Gastroenterology 2018 18:132

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  5. Content type: Research article

    Synchronous polypectomy in colonic malignancies is contentious due to the perceived risks of tumour implantation at polypectomy sites (PS). We assess the risks of tumour implantation after synchronous polypect...

    Authors: W. J. Tan, N. ZP. Ng, Y. D. Chen, Y. H. M. Chee, F. J. Foo, C. L. Tang and M. H. Chew

    Citation: BMC Gastroenterology 2018 18:133

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  6. Content type: Research article

    Alteration of the gut microbiota by repeated antibiotic treatment increases susceptibility to Clostridioides difficile infection. Faecal microbiota transplantation from donors with a normal microbiota effectively...

    Authors: Jillian R.-M. Brown, Burkhardt Flemer, Susan A. Joyce, Akbar Zulquernain, Donal Sheehan, Fergus Shanahan and Paul W. O’Toole

    Citation: BMC Gastroenterology 2018 18:131

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  7. Content type: Case report

    Iguratimod is a novel anti-rheumatic drug with the capability of anti-cytokines as report goes. It has been reported that iguratimod is effective and safe for rheumatoid arthritis and other rheumatisms. As sid...

    Authors: Xiao-li Li, Xiao-Chang Liu, Yu-Lin Song, Ru-Tao Hong and Hai Shi

    Citation: BMC Gastroenterology 2018 18:130

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  8. Content type: Research article

    Anorexia nervosa (AN) concerns approximately up to 1.8% of the pediatric female population. One of the complications that can occur in the course of this disease is acute liver failure. This study’s objective ...

    Authors: Katarzyna Górowska-Kowolik, Agata Chobot and Jarosław Kwiecień

    Citation: BMC Gastroenterology 2018 18:126

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  9. Content type: Research article

    A variety of extra-intestinal manifestations (EIMs), including hepatobiliary complications, are associated with inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) have been shown to play a potenti...

    Authors: Guo chao Niu, Lei Liu, Libo Zheng, Hong Zhang, David Q. Shih and Xiaolan Zhang

    Citation: BMC Gastroenterology 2018 18:127

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  10. Content type: Research article

    Antibiotic-associated diarrhea (AAD) is a side-effect frequently associated with the use of broad spectrum antibiotics. Although a number of clinical studies show that co-administration of specific probiotics ...

    Authors: Valeria Agamennone, Cyrille A. M. Krul, Ger Rijkers and Remco Kort

    Citation: BMC Gastroenterology 2018 18:103

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  11. Content type: Research article

    Endoscopic submucosal dissection (ESD) of the postoperative stomach (ESD-P) for early gastric cancer (EGC) is considered a technically difficult procedure. However, it is difficult to compare the outcomes of E...

    Authors: Mitsuru Esaki, Sho Suzuki, Yasuyo Hayashi, Azusa Yokoyama, Shuichi Abe, Taizo Hosokawa, Shinichi Tsuruta, Yosuke Minoda, Yoshitaka Hata, Haruei Ogino, Hirotada Akiho, Eikichi Ihara and Yoshihiro Ogawa

    Citation: BMC Gastroenterology 2018 18:125

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  12. Content type: Research article

    Currently, no standard of care or therapies have been established for patients with advanced HCC. We evaluated the efficacy and safety of conventional transarterial chemoembolization using gelatin sponges or m...

    Authors: Yi-Sheng Liu, Chia-Ying Lin, Ming-Tsung Chuang, Chia-Ying Lin, Yi-Shan Tsai, Chien-Kuo Wang and Ming-Ching Ou

    Citation: BMC Gastroenterology 2018 18:124

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  13. Content type: Research article

    The vertical transmission of HBV from mothers to their infants at birth or in early infancy has a significant role in the endemicity of HBV infection. Tenofovir is one of the most potent anti-HBV agents with a...

    Authors: Wenhui Li, Li Jia, Xin Zhao, Xiaoyuan Wu and Hongxia Tang

    Citation: BMC Gastroenterology 2018 18:121

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  14. Content type: Case report

    Acute pancreatitis is an acute inflammation of the pancreas that varies in severity from mild to life threatening usually requiring hospitalization. The true incidence of drug-induced pancreatitis (DIP) is ind...

    Authors: Sana Chams, Skye El Sayegh, Mulham Hamdon, Sarwan Kumar and Vesna Tegeltija

    Citation: BMC Gastroenterology 2018 18:122

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  15. Content type: Research article

    The mortality due to hemorrhage of esophageal varices (EV) is still high. The predominant cause for EV is liver cirrhosis, which has a high prevalence in Western Europe. Therefore, non-invasive screening marke...

    Authors: Birgit Tsaknakis, Rawan Masri, Ahmad Amanzada, Golo Petzold, Volker Ellenrieder, Albrecht Neesse and Steffen Kunsch

    Citation: BMC Gastroenterology 2018 18:123

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  16. Content type: Research article

    Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC). Nonetheless, the relevance o...

    Authors: Takahiro Shimoyama, Takayuki Yamamoto, Satoru Umegae and Koichi Matsumoto

    Citation: BMC Gastroenterology 2018 18:120

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  17. Content type: Research article

    Stress is a common contributing factor for irritable bowel syndrome (IBS). This study was to evaluate the efficacy of the centralized health education program in improving the quality of life (QOL) of middle s...

    Authors: Shi-Cheng Zheng, Hui Gong, Yi-Ping Wang, Qiang Zhang, Li-Li Wang, Xue-Fen Liao, Dai-Wen He and Jing Wu

    Citation: BMC Gastroenterology 2018 18:119

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  18. Content type: Study protocol

    Obesity is a global problem leading to reduced life expectancy, cardiovascular diseases, diabetes and many types of cancer. Even people willing to accept treatment only achieve a mean weight loss of about 5 kg...

    Authors: Marcus Hollenbach, Christiane Prettin, Felix Gundling, Wolfgang Schepp, Jochen Seufert, Jürgen Stein, Thomas Rösch, Jens Aberle, Jürgen Feisthammel, David Petroff and Albrecht Hoffmeister

    Citation: BMC Gastroenterology 2018 18:118

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  19. Content type: Research article

    Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal disorders worldwide, with relevant impact on the quality of life and health care costs.The aim of our study is to assess the pr...

    Authors: Irene Martinucci, Michela Natilli, Valentina Lorenzoni, Luca Pappalardo, Anna Monreale, Giuseppe Turchetti, Dino Pedreschi, Santino Marchi, Roberto Barale and Nicola de Bortoli

    Citation: BMC Gastroenterology 2018 18:116

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  20. Content type: Research article

    Anastomotic leakage (AL) is the most serious and common complication of surgery for rectal cancer, and associated risk factors remain unknown despite developments in laparoscopic surgery. The present study aim...

    Authors: Seiichi Shinji, Yoshibumi Ueda, Takeshi Yamada, Michihiro Koizumi, Yasuyuki Yokoyama, Goro Takahashi, Masahiro Hotta, Takuma Iwai, Keisuke Hara, Kohki Takeda, Mikihiro Okusa, Hayato Kan, Eiji Uchida and Hiroshi Yoshida

    Citation: BMC Gastroenterology 2018 18:117

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  21. Content type: Research article

    Patients with familial adenomatous polyposis (FAP) frequently undergo colectomy to reduce the 70 to 90% lifetime risk of colorectal cancer. After risk-reducing colectomy, duodenal cancer and complications from...

    Authors: Danielle C. Sample, N. Jewel Samadder, Lisa M. Pappas, Kenneth M. Boucher, Wade S. Samowitz, Therese Berry, Michelle Westover, Deepika Nathan, Priyanka Kanth, Kathryn R. Byrne, Randall W. Burt and Deborah W. Neklason

    Citation: BMC Gastroenterology 2018 18:115

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  22. Content type: Research article

    Non-alcoholic fatty liver disease (NAFLD) comprises non-progressive steatosis and non-alcoholic steatohepatitis (NASH), the latter of which may cause cirrhosis and hepatocellular carcinoma (HCC). As NAFLD dete...

    Authors: Tilman Kühn, Tobias Nonnenmacher, Disorn Sookthai, Ruth Schübel, Daniel Antonio Quintana Pacheco, Oyunbileg von Stackelberg, Mirja E. Graf, Theron Johnson, Christopher L. Schlett, Romy Kirsten, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor and Johanna Nattenmüller

    Citation: BMC Gastroenterology 2018 18:113

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  23. Content type: Research article

    Previous studies have indicated that bile acid is associated with progression of liver cirrhosis. However, the particular role of specific bile acid in the development of liver cirrhosis is not definite. The p...

    Authors: Zhimin Liu, Zhifeng Zhang, Mei Huang, Xiaoping Sun, Bojia Liu, Qiyang Guo, Qingshan Chang and Zhijun Duan

    Citation: BMC Gastroenterology 2018 18:112

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  24. Content type: Research article

    Graft-versus-host disease (GVHD) is a common complication of allo-hematopoietic stem cell transplantation (allo-HSCT). Endoscopic biopsy can provide a definitive diagnosis, but the optimal endoscopic approach ...

    Authors: Yuusaku Sugihara, Sakiko Hiraoka, Nobuharu Fujii, Shiho Takashima, Yasushi Yamasaki, Toshihiro Inokuchi, Masahiro Takahara, Kenji Kuwaki, Keita Harada, Takehiro Tanaka and Hiroyuki Okada

    Citation: BMC Gastroenterology 2018 18:111

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  25. Content type: Correction

    After publication of the original article [1], the authors reported that the Acknowledgments section was incomplete. The full section is the following:

    Authors: Amira Widyasari, Winona Alda Pravitasari, Andi Dwihantoro and Gunadi

    Citation: BMC Gastroenterology 2018 18:110

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    The original article was published in BMC Gastroenterology 2018 18:56

  26. Content type: Research article

    Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. Worldwide, 6.3 to 33% of the general populati...

    Authors: Bashu Dev Pardhe, Shreena Shakya, Anjeela Bhetwal, Jennifer Mathias, Puspa Raj Khanal, Roshan Pandit, Jyotsna Shakya, Hari Om Joshi and Sujan Babu Marahatta

    Citation: BMC Gastroenterology 2018 18:109

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  27. Content type: Research article

    Acute pancreatitis (AP) is associated with considerable morbidity and mortality. Current severity scores include multiple variables and some of them are only complete within 48 h of admission. Red cell distrib...

    Authors: Marta Gravito-Soares, Elisa Gravito-Soares, Dário Gomes, Nuno Almeida and Luís Tomé

    Citation: BMC Gastroenterology 2018 18:108

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  28. Content type: Research article

    Progressive familial intrahepatic cholestasis (PFIC) is caused by variations in ATP8B1, ABCB11 or ABCB4 genes. Data on genetic variations in Indian patients with PFIC are lacking.

    Authors: Anjali Sharma, Ujjal Poddar, Shikha Agnihotry, Shubha R. Phadke, Surender K. Yachha and Rakesh Aggarwal

    Citation: BMC Gastroenterology 2018 18:107

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  29. Content type: Research article

    Recently, although studies have investigated the role of NSAIDs in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP), selection of the ideal drug, the time and route of i...

    Authors: Yunxiao Lyu, Yunxiao Cheng, Bin Wang, Yueming Xu and Weibing Du

    Citation: BMC Gastroenterology 2018 18:106

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  30. Content type: Research article

    Malignant growth and metastasis of gastrointestinal stromal tumors (GIST) occur in some patients even during the course of treatment, but their mechanisms remains poorly understand at the molecular level so far.

    Authors: Chaoyong Shen, Yuan Yin, Huijiao Chen, Ruixue Wang, Xiaonan Yin, Zhaolun Cai, Bo Zhang, Zhixin Chen and Zongguang Zhou

    Citation: BMC Gastroenterology 2018 18:105

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  31. Content type: Research article

    Laparoscopic pancreaticoduodenectomy (LPD) remains to be established as a safe and effective alternative to open pancreaticoduodenectomy (OPD) for pancreatic-head and periampullary malignancy. The purpose of t...

    Authors: Ke Chen, Xiao-long Liu, Yu Pan, Hendi Maher and Xian-fa Wang

    Citation: BMC Gastroenterology 2018 18:102

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  32. Content type: Research article

    Percutaneous endoscopic gastrostomy (PEG) is a relatively safe procedure; however, acute and chronic complications of PEG have been reported. We aimed to determine risk factors associated with complications an...

    Authors: Gyu Young Pih, Hee Kyong Na, Ji Yong Ahn, Kee Wook Jung, Do Hoon Kim, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Gin Hyug Lee and Hwoon-Yong Jung

    Citation: BMC Gastroenterology 2018 18:101

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  33. Content type: Research article

    The classifications and counts of white blood cells (WBCs) have been proved to be able to be used as prognostic markers in cancer cases. The present study investigated the potential values of the classificatio...

    Authors: Yin-Ling Wang, Xin-Xin Ge, Yi Wang, Meng-Dan Xu, Fei-Ran Gong, Min Tao, Wen-Jie Wang, Liu-Mei Shou, Kai Chen, Meng-Yao Wu and Wei Li

    Citation: BMC Gastroenterology 2018 18:99

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  34. Content type: Research article

    This study aims to compare the performance of AIMS65, Glasgow–Blatchford (GBS) and Rockall scores (RS) in predicting the death risk among emergency-hospitalized patients with upper gastrointestinal bleeding (U...

    Authors: Lei Gu, Fei Xu and Jie Yuan

    Citation: BMC Gastroenterology 2018 18:98

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  35. Content type: Case report

    Pneumatosis cystoides intestinalis (PCI) is characterized by gas-filled cysts in the intestinal submucosa and subserosa. There are few reports of PCI occurring in duodenum and rectum. Here we demonstrated four...

    Authors: Yong juan Wang, Yu ming Wang, Yan min Zheng, Hui qing Jiang and Jie Zhang

    Citation: BMC Gastroenterology 2018 18:100

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  36. Content type: Case report

    Chronic Hepatitis C Virus (HCV) infection has been commonly linked to the development of autoimmunity, in part through activation of B cells. B cells are also postulated to play a pathogenic role in the autoim...

    Authors: Henry H. Nguyen, Abdullah Khathlan, Marvin J. Fritzler and Mark G. Swain

    Citation: BMC Gastroenterology 2018 18:97

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  37. Content type: Case report

    Transient infantile hypertriglyceridemia (HTGTI) is an autosomal recessive disorder caused by mutations in the glycerol-3-phosphate dehydrogenase 1 (GPD1) gene.

    Authors: Jia-Qi Li, Xin-Bao Xie, Jia-Yan Feng, Lian Chen, Kuerbanjiang Abuduxikuer, Yi Lu, Yu-Chuan Li and Jian-She Wang

    Citation: BMC Gastroenterology 2018 18:96

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  38. Content type: Research article

    A high rate of complete colon capsule endoscopy (CCE) investigations is required for a more widespread use of CCE. The objective of this study was to assess if coffee or chewing gum can increase excretion of t...

    Authors: Maria Magdalena Buijs, Morten Kobaek-Larsen, Lasse Kaalby and Gunnar Baatrup

    Citation: BMC Gastroenterology 2018 18:95

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  39. Content type: Research article

    Human rotavirus (HRV) is a major cause of viral gastroenteritis in infants; particularly in developing countries where malnutrition is prevalent. Malnutrition perturbs the infant gut microbiota leading to sub-...

    Authors: Anand Kumar, Anastasia N. Vlasova, Loic Deblais, Huang-Chi Huang, Asela Wijeratne, Sukumar Kandasamy, David D. Fischer, Stephanie N. Langel, Francine Chimelo Paim, Moyasar A. Alhamo, Lulu Shao, Linda J. Saif and Gireesh Rajashekara

    Citation: BMC Gastroenterology 2018 18:93

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  40. Content type: Study protocol

    Esophageal cancers accounted for nearly 16,000 deaths in 2016. The number of patients with esophageal cancers increases every year. Neoadjuvant chemoradiotherapy (nCRT) prior to esophagectomy is a standard tre...

    Authors: R. Taylor Ripley, Deborah R. Surman, Laurence P. Diggs, Jane B. Trepel, Min-Jung Lee, Jeremy Ryan, Jeremy L. Davis, Seth M. Steinberg, Jonathan M. Hernandez, Choung Hoang, Cara M. Kenney, Colleen D. Bond, Tricia F. Kunst, Anthony Letai and David S. Schrump

    Citation: BMC Gastroenterology 2018 18:94

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  41. Content type: Research article

    Current available treatments for Helicobacter pylori eradication are chosen according to local clarithromycin and metronidazole resistance prevalence. The aim of this study was to estimate, by means of molecular ...

    Authors: Patricio Gonzalez-Hormazabal, Maher Musleh, Susana Escandar, Hector Valladares, Enrique Lanzarini, V. Gonzalo Castro, Lilian Jara and Zoltan Berger

    Citation: BMC Gastroenterology 2018 18:91

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  42. Content type: Research article

    Submucosal hematoma has never been associated with caustic injuries. Long-term follow-up of patients who ingested ammonia is not well known and ammonia ingestion is rare.

    Authors: Moana Gelu-Simeon, Anh-Phuc Chuong, Faouzi Saliba, Guillaume Thiery, Marc Laurent, Claire Vilain, Marius Borel, Leonardo Amaral, Marceline Alexis, Georgette Saint-Georges and Eric Saillard

    Citation: BMC Gastroenterology 2018 18:92

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  43. Content type: Case report

    Hepatic cysts are the most frequent, innocuous, space-occupying lesions of the liver. The majority of solitary liver cysts are nonsymptomatic. When liver cysts reach a large size, there are some complications,...

    Authors: Cheng Zhang, Yue-Feng Ma and Yu-Long Yang

    Citation: BMC Gastroenterology 2018 18:90

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  44. Content type: Research article

    Unlike western world, gallstones and hypertriglyceridemia (HTG) are among the first two etiologies of acute pancreatitis (AP) in China. But yet, detailed differences in clinical features and outcomes between h...

    Authors: Xiaoyao Li, Lu Ke, Jie Dong, Bo Ye, Lei Meng, Wenjian Mao, Qi Yang, Weiqin Li and Jieshou Li

    Citation: BMC Gastroenterology 2018 18:89

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  45. Content type: Research article

    The epidemiology of inflammatory bowel disease (IBD) varies in different countries. This study aimed to assess phenotype, medications, prevalence and incidence of IBD in the State of Espírito Santo, Brazil.

    Authors: Adalberta Lima Martins, Rhaisa Almeida Volpato and Maria da Penha Zago-Gomes

    Citation: BMC Gastroenterology 2018 18:87

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  46. Content type: Case report

    Crohn’s Disease (CD) is typically characterized by abdominal symptoms, however, besides gastrointestinal symptoms, CD patients may suffer from extraintestinal manifestations which are far less common and medic...

    Authors: Arne Bokemeyer, Nicolas Tentrop, Peter J. Barth, Frank Lenze, Karin Hengst, Johannes Kleinheinz and Dominik Bettenworth

    Citation: BMC Gastroenterology 2018 18:88

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