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  1. Metabolic syndrome (MetS) is a worldwide pandemic and complex disorder associated with colorectal cancer (CRC). This study aims to identify the influence of number of MetS components on CRC incidence and morta...

    Authors: Kuan-Chih Chung, Sin-Ei Juang, Hong-Hwa Chen, Kung-Chuan Cheng, Kuen-Lin Wu, Ling-Chiao Song and Ko-Chao Lee
    Citation: BMC Gastroenterology 2022 22:453
  2. Patients with low HBV DNA levels (< 2000 IU/mL), HBV DNA negative, and HBsAg-negative hepatitis B virus(HBV)infection can still progress to decompensated cirrhosis; however, clinical research data in such pati...

    Authors: Xu Huang, Meimei Yan, Zerun Deng, Lei Yao, Dan Han and Lihua Sun
    Citation: BMC Gastroenterology 2022 22:452
  3. The aim of our study was to evaluate the curative effect and safety of stereotactic body radiation therapy (SBRT) in treating hepatocellular carcinoma (HCC) patients with inferior vena cava (IVCTT) and right a...

    Authors: Dan Zhang, Qian Li, Dong Li, Jun Jia, JunQiang Ding, Jing Sun and Xuezhang Duan
    Citation: BMC Gastroenterology 2022 22:451
  4. Hepatocellular carcinoma (HCC) is the most common neoplasm and the major cause of cancer-associated death worldwide. The high mortality rate of HCC is mainly attributed to its widespread prevalence and the lac...

    Authors: Rui Li, Chen Jin, Weiheng Zhao, Rui Liang and Huihua Xiong
    Citation: BMC Gastroenterology 2022 22:450
  5. This study aimed to develop and validate a nomogram to predict the risk of pancreatitis after percutaneous transhepatic biliary stent insertion (PTBS) in patients with malignant biliary obstruction (MBO).

    Authors: Chen Xu, Yiming Gu, Weizhong Zhou, Guoxiong Xu, Sheng Liu and Haibin Shi
    Citation: BMC Gastroenterology 2022 22:449
  6. Obesity, non-alcoholic fatty liver disease (NAFLD) and insulin resistance are three pathological conditions highly correlated, but this relationship is not fully elucidated. Hence, we aimed to assess the assoc...

    Authors: Kathrine Aglen Seeberg, Dag Hofsø, Heidi Borgeraas, John Olav Grimnes, Farhat Fatima, Lars Thomas Seeberg, Nils Petter Kvan, Marius Svanevik, Jens Kristoffer Hertel and Jøran Hjelmesæth
    Citation: BMC Gastroenterology 2022 22:448
  7. The incidence and diagnosis of inflammatory bowel disease (IBD) has increased considerably in recent years. Many clinical practice guidelines (CPG) have been developed for the management of this disease across...

    Authors: R. Zambrano-Sánchez, P. Alvarez-Mena, D. Hidalgo, C. M. Escobar Liquitay, J. V. A. Franco, R. W. M. Vernooij, D. Simancas-Racines, A. Viteri-García and C. Montesinos-Guevara
    Citation: BMC Gastroenterology 2022 22:447
  8. We analysed the survival of colorectal cancer (CRC) patients with lung metastasis and lung-only metastasis and determined the risk factors for lung metastasis in CRC patients.

    Authors: Lin-Lin Liu, Jun-Die Sun and Zuo-Lin Xiang
    Citation: BMC Gastroenterology 2022 22:446
  9. This study aimed to evaluate the usefulness of discharge standards in outpatients undergoing sedative endoscopy by comparing the modified post-anesthetic discharge scoring system (MPADSS) and the modified Aldr...

    Authors: Daisuke Yamaguchi, Tomohito Morisaki, Yasuhisa Sakata, Yumi Mizuta, Goshi Nagatsuma, Suma Inoue, Akane Shimakura, Amane Jubashi, Yuki Takeuchi, Kei Ikeda, Yuichiro Tanaka, Wataru Yoshioka, Naoyuki Hino, Keisuke Ario, Seiji Tsunada and Motohiro Esaki
    Citation: BMC Gastroenterology 2022 22:445
  10. Aberrant cytokeratin 7 expression by hepatocytes (CK7+Hs) is the hallmark characteristic of cholestasis diseases, especially in ductopenia diseases such as primary biliary cholangitis (PBC). This study attempted ...

    Authors: Hong-Li Liu, An-Yin Yang, Qing-Fang Xiong, Yan-Dan Zhong, Du-Xian Liu, Ping Huang, Xiao-Ning Feng, Yu Zhang and Yong-Feng Yang
    Citation: BMC Gastroenterology 2022 22:443
  11. Gamma-glutamyl transpeptidase to platelet ratio (GPR) and gamma-glutamyl transpeptidase to lymphocyte ratio (GLR) are assumed to be prognostic factors in liver fibrosis, cirrhosis and hepatocellular carcinoma....

    Authors: Weijie Chen, Danmian Hong, Zeliang Chen, Xiaoqing Dai, Jing Cao, Min Yu and Liping Li
    Citation: BMC Gastroenterology 2022 22:442
  12. Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths worldwide every year, and most HCC patients are diagnosed with advanced disease and can only receive systemic treatment. TKIs...

    Authors: Xiaoying Gu, Su Zhang, Xuejiao Yang, Tao Guan, Zhenyu Hou, Manqing Cao, Huikai Li and Ti Zhang
    Citation: BMC Gastroenterology 2022 22:441
  13. To establish a prediction model for acute gastrointestinal injury (AGI) in patients with prolonged disorder of consciousness (pDOC) and to evaluate and apply the prediction model. 

    Authors: Wenpei Fu, Zhihang Hu, Xiaomei Zhou, Liang Chen, Mei Wang, Yingying Zhu and Yinliang Qi
    Citation: BMC Gastroenterology 2022 22:440
  14. Patients with Rockall scores ≥6 have an increased risk of long-term peptic ulcer rebleeding. This study was aimed toward investigating whether an extended course of oral esomeprazole up to 1 year decreased ulc...

    Authors: Hsueh-Chien Chiang, Er-Hsiang Yang, Huang-Ming Hu, Wei-Ying Chen, Wei-Lun Chang, Chung-Tai Wu, Deng-Chyang Wu, Bor-Shyang Sheu and Hsiu-Chi Cheng
    Citation: BMC Gastroenterology 2022 22:439
  15. The prevalence and risk factors of eating disorders among patients with IBD are poorly described in existing literature. Early recognition and intervention may influence clinical outcomes in both physical and ...

    Authors: Gianna Stoleru, Andrew Leopold, Amanda Auerbach, Shelley Nehman and Uni Wong
    Citation: BMC Gastroenterology 2022 22:438
  16. Selenium-binding protein 1 (SELENBP1), a member of the selenium-containing protein family, plays an important role in malignant tumorigenesis and progression. However, it is currently lacking research about re...

    Authors: Cheng Zhu, Siya Wang, Yishan Du, Ying Dai, Qian Huai, Xiaolei Li, Yingying Du, Hanren Dai, Wenkang Yuan, Shi Yin and Hua Wang
    Citation: BMC Gastroenterology 2022 22:437
  17. Portal hypertensive gastropathy (PHG) is often underestimated in clinical diagnosis. Gastrointestinal bleeding in cirrhosis of PHG accounts for approximately 10% of upper gastrointestinal bleeding. However, th...

    Authors: Ran Wu, Kunyi Liu, Chengyi Shi, Hui Tian and Na Wang
    Citation: BMC Gastroenterology 2022 22:436
  18. Hospital readmissions in the first weeks following surgery are common, expensive, and associated with increased mortality among colorectal cancer patients. This study is designed to assess the 30-day hospital ...

    Authors: Mesnad S. Alyabsi, Anwar H. Alqarni, Latifah M. Almutairi, Mohammed A. Algarni, Kanan M. Alshammari, Adel Almutairi and Nahar A. Alselaim
    Citation: BMC Gastroenterology 2022 22:434
  19. Liver diseases post-COVID-19 vaccination is extremely rare but can occur. A growing body of evidence has indicated that portal vein thrombosis, autoimmune hepatitis, raised liver enzymes and liver injuries, et...

    Authors: Saad Alhumaid, Abbas Al Mutair, Ali A. Rabaan, Fatemah M. ALShakhs, Om Prakash Choudhary, Shin Jie Yong, Firzan Nainu, Amjad Khan, Javed Muhammad, Fadil Alhelal, Mohammed Hussain Al Khamees, Hussain Ahmed Alsouaib, Ahmed Salman Al Majhad, Hassan Redha AL-Tarfi, Ali Hussain ALyasin, Yaqoub Yousef Alatiyyah…
    Citation: BMC Gastroenterology 2022 22:433
  20. Functional dyspepsia (FD) is diagnosed based on self-reported symptoms and negative upper gastrointestinal endoscopic findings. The Rome criteria were not adopted as a diagnostic instrument in clinical guideli...

    Authors: Leonard Ho, Shuijiao Chen, Fai Fai Ho, Charlene H. L. Wong, Jessica Y. L. Ching, Pui Kuan Cheong, Irene X. Y. Wu, Xiaowei Liu, Ting Hung Leung, Justin C. Y. Wu and Vincent C. H. Chung
    Citation: BMC Gastroenterology 2022 22:432
  21. Immune checkpoint inhibitors have shown promise in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) advanced colorectal cancer (CRC) immunotherapy, and many clinical trials have been cond...

    Authors: Yuegang Li, Yuwei Du, Chi Xue, Pei Wu, Nan Du, Guolian Zhu, Huimian Xu and Zhi Zhu
    Citation: BMC Gastroenterology 2022 22:431
  22. We aimed to evaluate the correlation between the pathological changes and multi-parameter MRI characteristics of liver regeneration (LR) in a standard partial hepatectomy (PH) rat model.

    Authors: Caixin Qiu, Shuangshuang Xie, Yajie Sun, Yongquan Yu, Kun Zhang, Xuyang Wang, Jinxia Zhu, Robert Grimm and Wen Shen
    Citation: BMC Gastroenterology 2022 22:430
  23. Gastric cancer is often comorbid with hypertension and diabetes mellitus and increases the mortality risk.

    Authors: Laicheng Wang, Dan Hu, Zongcheng Fan, Jianjian Yu, Shunpeng Zhang, Yunchai Lin, Xin Chen, Xiandong Lin, Xiyao Yan, Jinxiu Lin and Feng Peng
    Citation: BMC Gastroenterology 2022 22:429
  24. ColoDefense1.0 assay has demonstrated its excellent sensitivity and specificity for early detection of colorectal cancer (CRC) by detecting the methylation levels of SDC2 and SEPT9, while exhibited limitations on...

    Authors: Yanmiao Dai, Guodong Zhao, Jun Yang, Xilang Zhou, Shangmin Xiong, Xirong Lu, Liming Gao, Jianfang Wu, Zouhua Xu, Sujuan Fei, Minxue Zheng and Hongwei Xu
    Citation: BMC Gastroenterology 2022 22:428
  25. The prognosis of hepatocellular carcinoma (HCC) has been extensively studied. However, the impact on prognosis of stage I HCC has not been well studied at clincopathological, mutational and transcriptional lev...

    Authors: Zhiqiang Li, Hongqiang Gao, Xiang Zhang, Qiyu Liu and Gang Chen
    Citation: BMC Gastroenterology 2022 22:427
  26. Inflammatory bowel disease (IBD) has become a global public health problem. The prevalence of IBD in China increased annually in past two decades.

    Authors: Jianfeng Luo, Jiamin Zhong, Haiwen Li, Shijing Zhang, Liwan Zhang, Jiang-tao Hou, Junyu Ke, Huibiao Li, Fengbin Liu and Xin-lin Chen
    Citation: BMC Gastroenterology 2022 22:426
  27. New direct-acting antiviral therapies have revolutionized hepatitis C virus (HCV) infection therapy. Nonetheless, once liver cirrhosis is established, the risk of hepatocellular carcinoma (HCC) still exists de...

    Authors: Shen-Shong Chang, Hsiao-Yun Hu, Yu-Chin Chen, Yung-Feng Yen and Nicole Huang
    Citation: BMC Gastroenterology 2022 22:425
  28. Colonoscopy is a standard procedure for evaluating colon diseases and screening for colorectal cancer, and bowel cleanliness prior to colonoscopy is key. The aim of this study was to compare the bowel cleansin...

    Authors: Apichet Sirinawasatien, Pallop Sakulthongthawin, Kanokpoj Chanpiwat and Tanyaporn Chantarojanasiri
    Citation: BMC Gastroenterology 2022 22:424
  29. Differential diagnosis between tuberculous peritonitis and peritoneal carcinomatosis remains challenging in clinical practice; thus, in-patients diagnosed with tuberculous peritonitis or peritoneal carcinomato...

    Authors: Li Du, Xiuqi Wei, Zhuanglong Xiao, Hui Wang and Yuhu Song
    Citation: BMC Gastroenterology 2022 22:423
  30. The aim of our study was to investigate the clinical characteristics and pathogenesis of tumor-induced acute pancreatitis (AP), and to develop a reliable prediction model of the clinical features to guide the ...

    Authors: Linlin Zheng, Ping Zhao, Xiaoqian Peng, Yunhui Zhou, Yichen Bao, Yuling Sun and Lin Zhou
    Citation: BMC Gastroenterology 2022 22:422
  31. Biomarkers such as fecal calprotectin (FC) and fecal immunochemical occult blood tests (FIT) for ulcerative colitis (UC) are used in clinical practice. In this study, the effect of UC disease duration on FC wa...

    Authors: Natsuki Ishida, Masanao Kaneko, Yusuke Asai, Takahiro Miyazu, Satoshi Tamura, Shinya Tani, Mihoko Yamade, Moriya Iwaizumi, Yasushi Hamaya, Satoshi Osawa, Takahisa Furuta and Ken Sugimoto
    Citation: BMC Gastroenterology 2022 22:420
  32. Evidence regarding the relationship between serum uric acid-to-creatinine (SUA/Scr) ratio and non-alcoholic fatty liver disease (NAFLD) in Chinese non-obese people is still limited. Therefore, the present stud...

    Authors: Xiaoyu Wang, Yong Han, Yufei Liu and Haofei Hu
    Citation: BMC Gastroenterology 2022 22:419
  33. Early hepatocellular carcinoma (HCC) detection with non-invasive biomarkers remains an unmet clinical need. We aimed to construct a predictive model based on the pre-diagnostic levels of serum markers to predi...

    Authors: Liming Zheng, Zeyu Huang, Xiaoping Li, Meifang He, Xiaoqin Liu, Guojun Zheng, Xike Zhou and Longgen Liu
    Citation: BMC Gastroenterology 2022 22:418
  34. Endoscopic submucosal dissection (ESD) can provide a high en bloc resection rate and has been widely applied as curative treatment for early colorectal cancer (ECC). However, surgical treatment is occasionally...

    Authors: Jongbeom Shin, Eun Ran Kim, Hyun Joo Jang, Dong Hoon Baek, Dong-Hoon Yang, Bo-In Lee, Kwang Bum Cho, Jin Woong Cho, Sung-Ae Jung, Su Jin Hong and Bong Min Ko
    Citation: BMC Gastroenterology 2022 22:417
  35. Clarithromycin-based therapy is important for Helicobacter pylori eradication treatment. However, clarithromycin may increase cardiovascular risk. Hence, we investigated the association between clarithromycin use...

    Authors: Yen-Chun Chen, Yi-Da Li, Ben-Hui Yu and Yi-Chun Chen
    Citation: BMC Gastroenterology 2022 22:416
  36. Recent data based on large databases show that bowel preparation (BP) is associated with improved outcomes in patients undergoing elective colorectal surgery. However, it remains unclear whether BP in elective...

    Authors: Haoran Zhuo, Zheng Liu, Benjamin J. Resio, Jialiang Liu, Xishan Wang, Kevin Y. Pei and Yawei Zhang
    Citation: BMC Gastroenterology 2022 22:415
  37. The effectiveness of pancreatic duct (PD) stenting in the early stages of acute pancreatitis (AP) remains controversial. This study aimed to investigate the efficacy and safety of PD stenting in the early stag...

    Authors: Weijie Yao, Genwang Wang, Qi Wang, Feng Wang, Zuoquan Wang and Zuozheng Wang
    Citation: BMC Gastroenterology 2022 22:414
  38. One of the most important risk factors for Helicobacter pylori (H. pylori) infection is nutrition. Balanced diets with high antioxidant properties may have protective effects against the consequences of this i...

    Authors: Zohreh Ebrahimi, Mohsen Masoodi, Zahra Aslani, Sina Naghshi, Masoumeh Khalighi Sikaroudi and Farzad Shidfar
    Citation: BMC Gastroenterology 2022 22:413
  39. Guillain–Barré Syndrome is an immune mediated polyneuropathy. Ulcerative Colitis is an immune mediated chronic inflammatory condition mainly of the large intestine. Guillain–Barré Syndrome can present as a rar...

    Authors: Jayasundara Mudiyanselage Hishali Dahami Jayasundara, Vajira Tharanga Samarawickrama, Ranjith Peiris, Tilan Aponso and Danushi Abeynayake
    Citation: BMC Gastroenterology 2022 22:411
  40. Malignancy-related ascites accounts for approximately 10% of causes of ascites. Our AIM was to characterize the ascites fluid and correlate clinical outcomes in those with extrahepatic malignancy and ascites.

    Authors: Omar Alshuwaykh, Amanda Cheung, Aparna Goel, Allison Kwong, Renumathy Dhanasekaran, T. Tara Ghaziani, Aijaz Ahmed, Tami Daugherty, Deepti Dronamraju, Radhika Kumari, Mindie Nguyen, W. Ray Kim and Paul Yien Kwo
    Citation: BMC Gastroenterology 2022 22:410
  41. T1 colorectal cancers have a low lymph node metastasis rate and good prognosis. Thus, endoscopic resection is an attractive choice. This study aimed to describe the value of poorly differentiated cluster grade...

    Authors: Xiaolin Ji, Mei Kang, Xianzhi Zhao, Xiaoyu Li, Yingjie Guo, Ping Xie, Yanan Yu and Zibin Tian
    Citation: BMC Gastroenterology 2022 22:409
  42. Serum ferritin (SF), as an acute-phase response protein, is used to reflect the degree of oxidative stress and systemic inflammatory responses. This study was designed to assess the effect of elevated SF level...

    Authors: Jie Wang, Qing-xie Liu, Dong-ling Teng, Yan-bing Ding, Guo-tao Lu, Wei-juan Gong, Qing-tian Zhu, Fei Han and Wei-ming Xiao
    Citation: BMC Gastroenterology 2022 22:408
  43. Gastric lymphangioma is one of the highly rare benign tumors characterized by multilocular or unilocular lymphatic spaces. Herein, we report a case of lymphangioma in the gastric antrum.

    Authors: Kunhao Bai, Yujun Dai, Chen Jiang, Shiyong Lin and Guobao Wang
    Citation: BMC Gastroenterology 2022 22:407
  44. Common variable immunodeficiency (CVID) is a rare disease that affects children and adults and is often difficult to diagnose. Despite being one of the most frequent causes of immunodeficiency, involving gastr...

    Authors: Mariana Barros Marcondes, Cíntia Mitsue Pereira Susuki, Newton Key Hokama, Paula de Oliveira Montandon Hokama, Felipe Aguera Oliver, Paulo Sergio Chaib, Xingshun Qi and Fernando Gomes Romeiro
    Citation: BMC Gastroenterology 2022 22:406
  45. In acute pancreatitis, secondary infection of pancreatic necrosis is a complication that mostly necessitates interventional therapy. A reliable prediction of infected necrotizing pancreatitis would enable an e...

    Authors: Mats L. Wiese, Steffi Urban, Sabrina von Rheinbaben, Fabian Frost, Matthias Sendler, Frank Ulrich Weiss, Robin Bülow, Marie-Luise Kromrey, Quang Trung Tran, Markus M. Lerch, Birgit Schauer and Ali A. Aghdassi
    Citation: BMC Gastroenterology 2022 22:405
  46. Ischemia–reperfusion injury (IRI) is the pathophysiological hallmark of hepatic dysfunction after orthotopic liver transplantation (OLT). Related to IRI, early allograft dysfunction (EAD) after OLT affects sho...

    Authors: Katja Frick, Elisabeth A. Beller, Marit Kalisvaart, Philipp Dutkowski, Reto A. Schüpbach and Stephanie Klinzing
    Citation: BMC Gastroenterology 2022 22:404

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