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  1. Anorectal malignant melanoma (ARMM) and low rectal adenocarcinoma (LRAC) have some similarities in clinical behaviors, histopathological characteristics and ultrasonographic findings, diagnostic errors are com...

    Authors: Jingwen Yan, Jigang Jing, Shuang Wu, Lacong Geiru and Hua Zhuang
    Citation: BMC Gastroenterology 2022 22:165
  2. Dyspepsia is a common complaint in upper gastrointestinal disorders. It is described as predominant epigastric pain lasting for at least one month. Globally, peptic ulcer disease occurs in 3.5–32% of patients ...

    Authors: Belete Assefa, Abilo Tadesse, Zenahebezu Abay, Alula Abebe, Tsebaot Tesfaye, Melaku Tadesse and Ayenew Molla
    Citation: BMC Gastroenterology 2022 22:164
  3. Estimates of cervical lymph node (LN) metastasis in patients with middle and lower thoracic esophageal squamous cell carcinoma (ESCC) are important. A nomogram is a useful tool for individualized prediction.

    Authors: Zhaoyang Yan, Xinjian Xu, Juntao Lu, Yang You, Jinsheng Xu and Tongxin Xu
    Citation: BMC Gastroenterology 2022 22:163
  4. The long-term prognosis of patients with hepatitis B virus–related acute-on-chronic liver failure (HBV-ACLF) is not well characterised. We assessed long-term outcomes and the associated risk factors of HBV-ACL...

    Authors: Lu Wang, Wenxiong Xu, Xuejun Li, Dabiao Chen, Yeqiong Zhang, Yuanli Chen, Juan Wang, Qiumin Luo, Chan Xie and Liang Peng
    Citation: BMC Gastroenterology 2022 22:162
  5. Non-traumatic hemoperitoneum was a rare event with the risk of sudden death. Spontaneous rupture of hepatocellular carcinoma is the most intuitive diagnosis when hemoperitoneum occurs in cirrhotic patients who...

    Authors: W. S. Yu, M. H. Chang, H. L. Lee, Y. T. Lee, M. C. Tsai and C. C. Wang
    Citation: BMC Gastroenterology 2022 22:160
  6. Sarcopenia is associated with disability, mortality, and poorer survival in cirrhotic patients. For the evaluation of muscle volume, computed tomography (CT) is the most accurate tool. Unfortunately, it would ...

    Authors: Lalida Luengpradidgun, Naichaya Chamroonkul, Pimsiri Sripongpun, Apichat Kaewdech, Pramot Tanutit, Natee Ina and Teerha Piratvisuth
    Citation: BMC Gastroenterology 2022 22:159
  7. The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising at an exponential rate throughout the world. Given the confirmed association between nutritional status and NAFLD, this study aimed to inve...

    Authors: Nasir Talenezhad, Farhang Mirzavandi, Shahab Rahimpour, Amir Pasha Amel Shahbaz, Mohammad Mohammadi and Mahdieh Hosseinzadeh
    Citation: BMC Gastroenterology 2022 22:158
  8. Primary malignant melanoma of esophagus (PMME) is an extremely rare disease with poor prognosis. We aimed to determine the clinical characteristics and treatment outcomes of patients with PMME.

    Authors: Tae-Se Kim, Byung-Hoon Min, Yang Won Min, Hyuk Lee, Poong-Lyul Rhee, Jae J. Kim and Jun Haeng Lee
    Citation: BMC Gastroenterology 2022 22:157
  9. In this study, we aimed to identify the distribution of presenting laboratory and nonenhanced computed tomography (CT) imaging features within 48 h before percutaneous cholecystostomy (PC) and create a model t...

    Authors: Bai-Qing Chen, Feng Xie, Guo-Dong Chen, Xue Li, Xue Mao and Bao Jia
    Citation: BMC Gastroenterology 2022 22:155
  10. Various hemostatic devices have been utilized to reduce blood loss during hepatectomy. Nonetheless, a comparison between monopolar and bipolar coagulation, particularly their usefulness or inferiority, has bee...

    Authors: Ryuta Muraki, Yoshifumi Morita, Shinya Ida, Ryo Kitajima, Satoru Furuhashi, Makoto Takeda, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Atsuko Fukazawa, Takanori Sakaguchi, Mayu Fukushima, Eisaku Okada and Hiroya Takeuchi
    Citation: BMC Gastroenterology 2022 22:154
  11. Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest gastrointestinal cancers with a 5-year survival rate of less than 10%. Biomarkers for early PDAC detection are useful in treating patients with P...

    Authors: Haruki Odaka, Keiko Hiemori, Asako Shimoda, Kazunari Akiyoshi and Hiroaki Tateno
    Citation: BMC Gastroenterology 2022 22:153
  12. Gallbladder cancer (GBC) with liver metastasis is considered unresectable. However, there have been infrequent reports of long-term survival in patients with GBC and liver metastases. Therefore, we examined th...

    Authors: Ryota Higuchi, Hiroaki Ono, Ryusei Matsuyama, Yusuke Takemura, Shinjiro Kobayashi, Takehito Otsubo, Yuta Abe, Itaru Endo, Minoru Tanabe and Masakazu Yamamoto
    Citation: BMC Gastroenterology 2022 22:152
  13. Selective internal radiation therapy (SIRT) with yttrium-90 (90Y) resin microspheres is an established locoregional treatment option for unresectable hepatocellular carcinoma (HCC), which delivers a lethal dose o...

    Authors: Armeen Mahvash, Steven Chartier, Mark Turco, Paula Habib, Steven Griffith, Scott Brown and S. Cheenu Kappadath
    Citation: BMC Gastroenterology 2022 22:151
  14. Pneumatosis cystoides intestinalis (PCI) is a rare condition characterized by the presence of air collection within the subserosa and/or submucosa of the gastrointestinal wall. Due to the lack of specific symp...

    Authors: Liqing Yang, Xi Zhong, Hao Yang, Qin Wu, Yuping Gong and Bo Wang
    Citation: BMC Gastroenterology 2022 22:150
  15. Behçet’s disease (BD) is a recurrent multisystem inflammatory disease. Anti-tumor necrosis factor (TNF) α agents have been used to treat patients with intestinal BD with severe disease activity or those who ar...

    Authors: Haruka Miyazaki, Daisuke Watanabe, Norihiro Okamoto, Eri Tokunaga, Yuna Ku, Haruka Takenaka, Namiko Hoshi, Makoto Ooi and Yuzo Kodama
    Citation: BMC Gastroenterology 2022 22:149
  16. Many studies have focused on prophylactic therapy for post-endoscopic submucosal dissection (ESD) of esophageal strictures. However, various strategies cannot prevent the occurrence of postoperative strictures...

    Authors: Qing Lu, Jin Wang, Xiuhe Lv, Mingjia Xi, Tiantian Lei, Zijing Wang, Li Yang and Jinlin Yang
    Citation: BMC Gastroenterology 2022 22:147
  17. Analysis of the constituents of gallstones using various spectroscopic techniques assists in identification of the pathogenesis of gallstones. In the current study, using Fourier Transform Infra-Red (FTIR) Spe...

    Authors: Lena Jafri, Muhammad Abbas Abid, Humera Asif, Bilal Hashmi, Hafsa Majid, Farooq Ghani, Sibtain Ahmed, Imran Siddiqui and Aysha Habib Khan
    Citation: BMC Gastroenterology 2022 22:146
  18. Ornithine transcarbamylase deficiency (OTCD) is most common among urea cycle disorders (UCDs), defined by defects in enzymes associated with ureagenesis. Corticosteroid administration to UCD patients, includin...

    Authors: Koji Imoto, Masatake Tanaka, Takeshi Goya, Tomomi Aoyagi, Motoi Takahashi, Miho Kurokawa, Shigeki Tashiro, Masaki Kato, Motoyuki Kohjima and Yoshihiro Ogawa
    Citation: BMC Gastroenterology 2022 22:144
  19. Therapeutic options for inflammatory bowel disease (IBD) have increased since the introduction of tumour necrosis factor (TNF) inhibitors a few decades ago. However, direct comparisons of the effectiveness of ...

    Authors: Hye Kyung Hyun, Hyun-Soo Zhang, Jongwook Yu, Eun Ae Kang, Jihye Park, Soo Jung Park, Jae Jun Park, Tae Il Kim, Won Ho Kim and Jae Hee Cheon
    Citation: BMC Gastroenterology 2022 22:143
  20. The relationship between PROX1 expression and clinicopathological characteristics and prognosis in patients with gastric cancer (GC) remain controversial. The aim of this study is to determine the clinicopatho...

    Authors: Zirui Jia, Yuhang Wang, Jiacheng Gao and Guo Zu
    Citation: BMC Gastroenterology 2022 22:142
  21. Regional lymph node metastases are the main adverse prognostic factor in patients with rectal cancer without distant metastases. There are discrepancies, however, regarding additional risk factors in the group...

    Authors: Marcin Zeman, Władysław Skałba, Piotr Szymański, Grzegorz Hadasik, Dmytro Żaworonkow, Dominik A. Walczak and Agnieszka Czarniecka
    Citation: BMC Gastroenterology 2022 22:141
  22. Hospitalization admissions and discharge databases (DAD) using the International Classification of Diseases (ICD) codes are often used to describe the epidemiology of Clostridioides difficile infections (CDI) amo...

    Authors: Seth R. Shaffer, Zoann Nugent, Charles N. Bernstein, Andrew Walkty and Harminder Singh
    Citation: BMC Gastroenterology 2022 22:140
  23. It is unclear whether prophylactic endoscopic closure after colorectal endoscopic submucosal dissection (ESD) reduces the risk of postoperative adverse events due to variability in lesion characteristics. Ther...

    Authors: Jun Omori, Osamu Goto, Tsugumi Habu, Yumiko Ishikawa, Kumiko Kirita, Eriko Koizumi, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Teppei Akimoto, Naohiko Akimoto, Norio Itokawa, Mitsuru Kaise and Katsuhiko Iwakiri
    Citation: BMC Gastroenterology 2022 22:139

    The Correction to this article has been published in BMC Gastroenterology 2022 22:206

  24. Ulcerative colitis (UC) is a common inflammatory bowel disease, during which cell necroptosis plays key roles in driving inflammation initiation and aggravation. Previous studies reported Receptor Interacting ...

    Authors: Chaoqin Duan, Xi Xu, Xiaoyi Lu, Ling Wang and Zhongkai Lu
    Citation: BMC Gastroenterology 2022 22:137
  25. Pancreatic portal hypertension (PPH) is a type of extrahepatic portal hypertension. We compared the clinical efficacy of different treatment methods for PPH caused by splenic vein stenosis in chronic pancreati...

    Authors: Jingjing Liu, Qingbing Wang, Xiaoyi Ding, Qin Liu, Wei Huang, Junwei Gu, Zhongmin Wang, Wei Wu and Zhiyuan Wu
    Citation: BMC Gastroenterology 2022 22:136
  26. In a randomized controlled trial, lenvatinib was non-inferior to sorafenib in overall survival (OS) of patients with unresectable hepatocellular carcinoma (uHCC). This study aimed to compare the effects of sor...

    Authors: Na Ryung Choi, Ju Yeon Kim, Ji Hoon Hong, Moon Haeng Hur, Heejin Cho, Min Kyung Park, Jihye Kim, Yun Bin Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon and Yoon Jun Kim
    Citation: BMC Gastroenterology 2022 22:135
  27. Remnant cholesterol/high-density lipoprotein cholesterol (RC/HDL-C) ratio has been shown to be a good predictor of metabolic disease risk, but no studies have further investigated the role of RC/HDL-C ratio in...

    Authors: Yang Zou, Chong Hu, Maobin Kuang and Yuliang Chai
    Citation: BMC Gastroenterology 2022 22:134
  28. Reconstruction surgery-associated stricture frequently occurs in patients with long-gap esophageal atresia (LGEA). While several endoscopic dilatation methods have been applied and would be desirable, endoscop...

    Authors: Shin Kashima, Kentaro Moriichi, Yu Kobayashi, Yuya Sugiyama, Yuki Murakami, Takahiro Sasaki, Keitaro Takahashi, Katsuyoshi Ando, Nobuhiro Ueno, Hiroki Tanabe and Mikihiro Fujiya
    Citation: BMC Gastroenterology 2022 22:132
  29. Patients can present for a wide variety of etiologies for dysphagia, and it is important to consider less common causes once common etiologies have been ruled out. Extrapulmonary Mycobacterium tuberculosis (TB) p...

    Authors: Dylan Olson, Kevin C. Liu, Anthony P. Merza, Ermias Tilahun and A. Aziz Aadam
    Citation: BMC Gastroenterology 2022 22:131
  30. Although coexisting alcohol-induced liver disease and hepatitis B or C virus-induced liver cirrhosis (ALD + HBV or ALD + HCV) has been the center of recent hepatology researches, numerous controversies still p...

    Authors: Kodjo-Kunale Abassa, Xiao-Ying Wu, Xiu-Ping Xiao, Hao-Xiong Zhou, Yun-Wei Guo and Bin Wu
    Citation: BMC Gastroenterology 2022 22:130
  31. Immunoglobulin light chain (AL) amyloidosis commonly affects the kidney or heart, but may also involve the liver at a histopathological level. Early diagnosis of AL amyloidosis is important for proper manageme...

    Authors: Kehui Liu, Yezhou Ding, Yumin Xu, Weiliang Tang, Mingyang Feng, Yunye Liu, Shisan Bao and Hui Wang
    Citation: BMC Gastroenterology 2022 22:128
  32. Colon cancer remains one of the most common malignancies across the world. Thus far, a biomarker, which can comprehensively predict the survival outcomes, clinical characteristics, and therapeutic sensitivity,...

    Authors: Yonggan Xue, Bobin Ning, Hongyi Liu and Baoqing Jia
    Citation: BMC Gastroenterology 2022 22:127
  33. Using endoscopy as the reference, this study evaluated the accuracy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in measuring distance from the incisors to the PET de...

    Authors: Szu-Wei Hsu, Jeffrey S. Chang, Wei-Lun Chang, Forn-Chia Lin and Nan-Tsing Chiu
    Citation: BMC Gastroenterology 2022 22:126
  34. No studies have compared the performance of microvascular and microsurface patterns alone with their combination in patients undergoing magnifying endoscopy with narrow-band imaging for diagnosing gastric canc...

    Authors: Yusuke Horiuchi, Toshiaki Hirasawa, Naoki Ishizuka, Junki Tokura, Mitsuaki Ishioka, Yoshitaka Tokai, Ken Namikawa, Shoichi Yoshimizu, Akiyoshi Ishiyama, Toshiyuki Yoshio and Junko Fujisaki
    Citation: BMC Gastroenterology 2022 22:125
  35. Serum ceruloplasmin is one of the major diagnostic parameters for Wilson’s disease (WD). Age and gender difference of serum ceruloplasmin remain controversy. This study aims to assess diagnostic value of serum...

    Authors: Xinshuo Lu, Simin Li, Wen Zhang, Yunting Lin, Zhikun Lu, Yanna Cai, Xueying Su, Yongxian Shao, Zongcai Liu, Huiying Sheng, Yonglan Huang, Li Liu and Chunhua Zeng
    Citation: BMC Gastroenterology 2022 22:124
  36. Intraoperative near-infrared fluorescence (NIR) imaging with indocyanine green (ICG) can demonstrate real-time lymphatic drainage and thus improve the accuracy and completeness of lymphadenectomy in colorectal...

    Authors: Yanwu Sun, Yu Lin, Zhun Liu, Weizhong Jiang and Pan Chi
    Citation: BMC Gastroenterology 2022 22:123
  37. The prognostic value of intratumor T regulatory cells (Tregs) in colorectal cancer (CRC) was previously reported, but the role of these cells in tumor draining lymph nodes (TDLNs) was less addressed.

    Authors: Bing Yan, Jianmei Xiong, Qianwen Ye, Tianhui Xue, Jia Xiang, Mingyue Xu, Fang Li and Wei Wen
    Citation: BMC Gastroenterology 2022 22:122
  38. Previous studies have confirmed that systemic immune-inflammatory index (SII) and prognostic nutritional index (PNI) can predict the prognosis and chemotherapy efficacy of various malignant tumors. However, to...

    Authors: Ping’an Ding, Honghai Guo, Chenyu Sun, Peigang Yang, Na Hyun Kim, Yuan Tian, Yang Liu, Pengpeng Liu, Yong Li and Qun Zhao
    Citation: BMC Gastroenterology 2022 22:121
  39. The clinical characteristics of synchronous colorectal cancer (SCRC) reported in previous studies differ significantly. Furthermore, little is known about the characteristics of early-onset synchronous colorec...

    Authors: Huaxian Chen, Shi Yin, Zhizhong Xiong, Xianzhe Li, Fengxiang Zhang, Xijie Chen, Jianping Guo, Minghao Xie, Chaobin Mao, Longyang Jin and Lei Lian
    Citation: BMC Gastroenterology 2022 22:120
  40. The natural history and incidence of hepatocellular carcinoma (HCC) arising from indeterminate liver lesions are not well described. We aimed to define the incidence of HCC in a cohort of patients undergoing s...

    Authors: Sara Cococcia, Priti Dutta, Melika Moghim, Brian Hogan, Sudeep Tanwar, Aileen Marshall, Douglas Macdonald, Dominic Yu, James O’Beirne, William M. Rosenberg and Paul M. Trembling
    Citation: BMC Gastroenterology 2022 22:118
  41. Studies investigating the changes in short-chain fatty acids (SCFAs) in patients with ulcerative colitis (UC) have yielded inconsistent results. We performed a meta-analysis of studies that investigated the al...

    Authors: Hao-Ming Xu, Hai-Lan Zhao, Gong-Jing Guo, Jing Xu, You-Lian Zhou, Hong-Li Huang and Yu-Qiang Nie
    Citation: BMC Gastroenterology 2022 22:117
  42. Enteric fever is a systemic disease caused by Salmonella enterica serovar Typhi or Salmonella enterica serovar Paratyphi, characterized by high fever and abdominal pain. Most patients with enteric fever improve w...

    Authors: Hong Jae Jeon, Jong Seo Lee, Byung Seok Lee, Seok Hyun Kim, Eaum Seok Lee, Jae Kyu Sung, Hee Seok Moon, Sun Hyung Kang, Hyun Seok Lee, Seongwoo Choi, Heon Sa-Kong, Shinhye Cheon and Hyuk Soo Eun
    Citation: BMC Gastroenterology 2022 22:116

    The Correction to this article has been published in BMC Gastroenterology 2022 22:230

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