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  1. To determine the safety and efficacy of different doses of tolvaptan for treating Chinese cirrhotic patients with or without hyponatraemia who still had ascites after routine therapy with diuretics.

    Authors: Jieting Tang, Yongfeng Wang, Tao Han, Qing Mao, Jun Cheng, Huiguo Ding, Jia Shang, Qin Zhang, Junqi Niu, Feng Ji, Chengwei Chen, Jidong Jia, Xiangjun Jiang, Nonghua Lv, Yueqiu Gao, Zhenghua Wang…
    Citation: BMC Gastroenterology 2020 20:391
  2. Ultrasound (US) imaging is known to underestimate tumor size in clinical. This study is aimed to compare the size measurements of hepatocellular carcinoma (HCC) in three US imaging modalities, i.e. two-dimensi...

    Authors: Fei Chen, Fei Wang, Si Sun, Mei Zhu and Zheng Liu
    Citation: BMC Gastroenterology 2020 20:390
  3. The current virtual chromoendoscopy equipment cannot completely detect superficial squamous cell carcinoma (SCC) in the esophagus, despite its development in the recent years. Thus, in this study, we aimed to ...

    Authors: Taro Iwatsubo, Ryu Ishihara, Yasushi Yamasaki, Yusuke Tonai, Kenta Hamada, Minoru Kato, Sho Suzuki, Mitsuhiro Kono, Hiromu Fukuda, Yusaku Shimamoto, Kentaro Nakagawa, Masayasu Ohmori, Masamichi Arao, Kenshi Matsuno, Hiroyoshi Iwagami, Shuntaro Inoue…
    Citation: BMC Gastroenterology 2020 20:389
  4. The outbreak of COVID-19 and SARS-CoV-2 infection is spreading worldwide as the first coronavirus pandemic. The clinical picture is variable but flu-like symptoms are common with bilateral interstitial pneumon...

    Authors: Luca Elli, Donatella Barisani, Valentina Vaira, Maria Teresa Bardella, Matilde Topa, Maurizio Vecchi, Luisa Doneda, Alice Scricciolo, Vincenza Lombardo and Leda Roncoroni
    Citation: BMC Gastroenterology 2020 20:387

    The Correction to this article has been published in BMC Gastroenterology 2022 22:86

  5. In the correspondence from Abdurrahman et al., they raised three main concerns and critiques of our recently published article entitled “Syphilitic hepatitis: a case report and review of the literature”. First...

    Authors: Jiaofeng Huang, Bo Wan, Mingfang Wang, Yueyong Zhu and Su Lin
    Citation: BMC Gastroenterology 2020 20:385

    The original article was published in BMC Gastroenterology 2020 20:379

  6. Mucosal healing (MH) has been indicated as the therapeutic goal for ulcerative colitis (UC). Platelet count is known as an inflammation evaluation. However, the association between platelet count and MH among ...

    Authors: Shinya Furukawa, Sen Yagi, Kana Shiraishi, Kenichirou Mori, Tomoyuki Ninomiya, Keitarou Kawasaki, Yuji Mizukami, Seiyuu Suzuki, Masayoshi Uraoka, Naozumi Shibata, Sanae Nakamura, Satoshi Imamine, Hidehiro Murakami, Katsuhisa Ohashi, Masamoto Torisu, Aki Hasebe…
    Citation: BMC Gastroenterology 2020 20:384
  7. Development of gastrointestinal (GI) complications is adversely associated with prognosis in the critically ill. However, little is known about their impact on the outcome of non-critically ill patients. In th...

    Authors: Chun-Ta Huang, Chun-Ming Hong, Yi-Ju Tsai, Wang-Huei Sheng and Chong-Jen Yu
    Citation: BMC Gastroenterology 2020 20:383
  8. Amplification of HER2 gene (ERBB2) and overexpression of HER2 protein on cancer cells are found in 10–26% of gastric cancer (GC) and esophagogastric junction cancer (EGJC). Gene copy number variation (CNV) could ...

    Authors: Anna Grenda, Kamila Wojas-Krawczyk, Tomasz Skoczylas, Paweł Krawczyk, Jadwiga Sierocińska-Sawa, Grzegorz Wallner and Janusz Milanowski
    Citation: BMC Gastroenterology 2020 20:382
  9. Lipid profiles are declined in patients with viral liver cirrhosis and correlated with severity of liver disease. Hepatitis B virus (HBV) is the leading cause of liver cirrhosis in China. Our primary aim was t...

    Authors: Ran Cheng, Ning Tan, Qian Kang, Hao Luo, Hongyu Chen, Jiali Pan, Yifan Han, Yuqing Yang and Xiaoyuan Xu
    Citation: BMC Gastroenterology 2020 20:381
  10. Syphilis is a sexuality transmitted disease caused by Treponema pallidum. Liver involvement is very rarely seen and occurs in the second phase of the disease. Syphilitic hepatitis generally is mild clinical condi...

    Authors: Abdurrahman Kaya and Sibel Yıldız Kaya
    Citation: BMC Gastroenterology 2020 20:379

    The original article was published in BMC Gastroenterology 2019 19:191

    The Correspondence to this article has been published in BMC Gastroenterology 2020 20:385

  11. Hepatic artery dissection after liver transplantation is an uncommon morbidity. The onset mechanism and management for this disorder remain unclear. The present report describes the cases of two patients with ...

    Authors: Keita Shimata, Yasuhiko Sugawara, Tomoaki Irie, Yuzuru Sambommatsu, Masashi Kadohisa, Sho Ibuki, Seiichi Kawabata, Kaori Isono, Masaki Honda, Hidekazu Yamamoto and Taizo Hibi
    Citation: BMC Gastroenterology 2020 20:378
  12. We aimed to characterize the trends of prognosis in ulcerative colitis (UC) and Crohn’s disease (CD) in a Chinese tertiary hospital.

    Authors: Hong Lv, Meng Jin, Huimin Zhang, Xuanfu Chen, Meixu Wu, Mingyue Guo, Runing Zhou, Zheng Wang, Hong Yang and Jiaming Qian
    Citation: BMC Gastroenterology 2020 20:377

    The Correction to this article has been published in BMC Gastroenterology 2022 22:109

  13. The risk of recurrent colonic adenoma associated with high-grade dysplasia (HGD) colon polyps at baseline colonoscopy remains unclear. We conducted a clinical cohort study with patients who underwent polypecto...

    Authors: Jia-Jang Chang, Cheng-Hung Chien, Shuo-Wei Chen, Li-Wei Chen, Ching-Jung Liu and Cho-Li Yen
    Citation: BMC Gastroenterology 2020 20:376
  14. Portal vein thrombosis (PVT) occurs frequently in hepatocellular carcinoma (HCC) and is often diagnosed in the course of a routine patient evaluation and surveillance for liver cancer. The purpose of this stud...

    Authors: Giulia Malaguarnera, Vito Emanuele Catania, Saverio Latteri, Antonio Maria Borzì, Gaetano Bertino, Roberto Madeddu, Filippo Drago and Michele Malaguarnera
    Citation: BMC Gastroenterology 2020 20:375
  15. The role of common bile duct (CBD) stenting in the establishment of bile stream in the elderly patients and the ones who are not good candidates for surgery due to not responding to treatments was well documen...

    Authors: Ahmad Hormati, Mohammad Reza Ghadir, Seyed Saeed Sarkeshikian, Faezeh Alemi, Majid Moghaddam, Sajjad Ahmadpour, Abolfazl Mohammadbeigi and Gholam Reza Sivandzadeh
    Citation: BMC Gastroenterology 2020 20:374
  16. The microsatellite instability (MSI) in colorectal cancer (CRC) has a more favorable clinical outcome and is characterized by highly upregulated expression of various immunological checkpoints than microsatell...

    Authors: Wen-juan Huang, Xin Wang, Meng-lin Zhang, Li Li and Rui-tao Wang
    Citation: BMC Gastroenterology 2020 20:373
  17. Inflammatory bowel disease (IBD) is a debilitating chronic disease with limited treatment options. Resistant starches may represent a novel treatment for IBD. However, its efficacy and safety remain unclear. O...

    Authors: Joshua Montroy, Rania Berjawi, Manoj M. Lalu, Eyal Podolsky, Cayden Peixoto, Levent Sahin, Alain Stintzi, David Mack and Dean A. Fergusson
    Citation: BMC Gastroenterology 2020 20:372
  18. Sarcopenia is a syndrome characterized by progressive and systemic decreases in skeletal muscle mass and muscle strength. The influence or prognosis of various liver diseases in this condition have been widely...

    Authors: Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, Kentaro Tanaka, Satoshi Narahara, Takayuki Tokunaga, Takeshi Kawasaki, Yoko Yoshimaru, Katsuya Nagaoka, Takehisa Watanabe, Hiroko Setoyama, Yutaka Sasaki and Yasuhito Tanaka
    Citation: BMC Gastroenterology 2020 20:371
  19. Despite zinc finger and BTB domain-containing 7A (ZBTB7A) documented importance in multiple tumors, the function and clinical value in Colorectal cancer (CRC) remain elusive. The aim of this study was to evalu...

    Authors: Li Wang, Meng-Xia Zhang, Mei-Fang Zhang and Zi-Wei Tu
    Citation: BMC Gastroenterology 2020 20:370
  20. The prognostic factors of morbidity and mortality in patients with lean NAFLD (body mass index < 25.0 kg/m2) are unknown.

    Authors: Soichi Iritani, Norio Akuta, Yusuke Kawamura, Akira Kajiwara, Kayoko Kasuya, Shunichiro Fujiyama, Hitomi Sezaki, Tetsuya Hosaka, Masahiro Kobayashi, Mariko Kobayashi, Satoshi Saito, Fumitaka Suzuki, Yasuji Arase, Kenji Ikeda, Yoshiyuki Suzuki and Hiromitsu Kumada
    Citation: BMC Gastroenterology 2020 20:368
  21. Using fluorescence in situ hybridisation (FISH) to detect any gain of chromosomes 3, 7, or 17 and loss of the 9p21 locus has been proven to be sensitive in the diagnosis of pancreatobiliary tumors. However, bo...

    Authors: Xiaohong Pu, Hongwei Zheng, Xin Yang, Qing Ye, Zhiwen Fan, Jun Yang, Xiangshan Fan, Xiaoping Zhou, Yudong Qiu, Qin Huang, Hongyan Wu and Jun Chen
    Citation: BMC Gastroenterology 2020 20:367
  22. The occurrence of non-alcoholic fatty liver disease (NAFLD) is found to be higher in patients with obstructive sleep apnea (OSA), which is characterized by intermittent hypoxia. Activation of hypoxia-inducible...

    Authors: Xiaofang Zhang, Caoxin Huang, Xuejun Li, Zhaoshui Shangguan, Wenjing Wei, Suhuan Liu, Shuyu Yang and Yijie Liu
    Citation: BMC Gastroenterology 2020 20:366
  23. Nasogastric intubation (NGI) is usually challenging in patients under general anesthesia, with reported success rate at the first attempt to be less than 50%. The aim of this study was to investigate whether a...

    Authors: Ting-Yang Huang, Jr-Rung Lin and Yung-Tai Chung
    Citation: BMC Gastroenterology 2020 20:365
  24. A full spectrum of video capsule endoscopy (VCE) adverse events over the past two decades has not been evaluated. We aimed to determine pooled rates, predictors and temporal-trend of VCE adverse events over th...

    Authors: Yuan-Chen Wang, Jun Pan, Ya-Wei Liu, Feng-Yuan Sun, Yang-Yang Qian, Xi Jiang, Wen-Bin Zou, Ji Xia, Bin Jiang, Nan Ru, Jia-Hui Zhu, En-Qiang Linghu, Zhao-Shen Li and Zhuan Liao
    Citation: BMC Gastroenterology 2020 20:364
  25. The development of gallbladder disease (GBD) is related to bile acid (BA) metabolism, and the rate of BA circulation increases the risk of biliary cancer. However, it is unclear whether patterns of circulating...

    Authors: Linshi Wu, Yinping Wang, Sibo Zhu, Xunxia Bao, Zhiliang Fu, Timing Zhen, Zhiqing Yuan, Qiwei Li, Zheng Deng, Jianhua Sun and Tao Chen
    Citation: BMC Gastroenterology 2020 20:363
  26. A care pathway for nonalcoholic fatty liver disease (NAFLD) in Kaiser Permanente San Diego, California was instituted in August 2017 to improve efficiency of disease staging and promote lifestyle modification.

    Authors: Heather Patton, Raoul Burchette, Stephanie Tovar, Jose Pio, Jiaxiao Shi and Lisa M. Nyberg
    Citation: BMC Gastroenterology 2020 20:362
  27. Gastric varices are encountered less frequently than esophageal varices. Nonetheless, gastric variceal bleeding is more severe and associated with worse outcomes. Conventionally, gastric varices have been desc...

    Authors: Cyriac Abby Philips, Rizwan Ahamed, Sasidharan Rajesh, Tom George, Meera Mohanan and Philip Augustine
    Citation: BMC Gastroenterology 2020 20:361
  28. The prison population is considered at high risk of acquiring infectious diseases due to confined conditions, behavioral factors, injection drug use, unprotected sexual activity, non-professional tattooing and...

    Authors: Ifeyinwa M. Okafor, Solomon O. Ugwu and Henshaw U. Okoroiwu
    Citation: BMC Gastroenterology 2020 20:360
  29. To develop the Patient Health Questionnaire-8 (PHQ-8) as a more reliable approach than the Somatic Symptom Scale-8 (SSS-8), evaluating somatization which might be a critical factor influencing the quality of l...

    Authors: Chaoqun Yuan, Guizhen Yong, Xi Wang, Ting Xie, Chunyan Wang, Yuan Yuan and Guobin He
    Citation: BMC Gastroenterology 2020 20:359
  30. Thymic carcinoma is a rare mediastinal neoplasm with a high malignant potential. It often shows pleural invasion and distant metastasis. The metastasis of thymic carcinoma to the small intestine is rarely repo...

    Authors: Yi Yuan, Hong Pu, Ming-hui Pang, Yi-sha Liu and Hang Li
    Citation: BMC Gastroenterology 2020 20:358
  31. Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a vasculitis that mostly occurs in young children. Adult-onset KD (AKD) is rare and often misdiagnosed. Here we report a rare case of KD with chole...

    Authors: Massimo Gallerani, Marco Pala, Fabio Fabbian and Alfredo De Giorgi
    Citation: BMC Gastroenterology 2020 20:357
  32. With more prevalent gastroesophageal reflux disease comes increased cases of Barrett's esophagus and esophageal adenocarcinoma. Image-enhanced endoscopy using linked-color imaging (LCI) differentiates between ...

    Authors: Tsutomu Takeda, Daisuke Asaoka, Daiki Abe, Maiko Suzuki, Yuta Nakagawa, Hitoshi Sasaki, Yoshihiro Inami, Muneo Ikemura, Hisanori Utsunomiya, Shotaro Oki, Nobuyuki Suzuki, Atsushi Ikeda, Noboru Yatagai, Hiroyuki Komori, Yoichi Akazawa, Kohei Matsumoto…
    Citation: BMC Gastroenterology 2020 20:356
  33. Diarrhea is a common adverse event of fluoropyrimidine-based chemotherapy. However, limited data are available on the frequency and risk factors of complicated chemotherapy-induced diarrhea (CID) and small int...

    Authors: Miho Sakumura, Takayuki Ando, Ayumu Hosokawa, Takahiko Nakajima, Iori Motoo, Hiroshi Mihara, Akira Ueda, Shinya Kajiura, Sohachi Nanjo, Haruka Fujinami, Kohei Ogawa and Ichiro Yasuda
    Citation: BMC Gastroenterology 2020 20:355
  34. Placement of feeding jejunostomy (PFJ) during esophagectomy is an effective method to maintain adequate nutrition, but is associated with serious complications such as bowel obstruction and jejunal torsion. Th...

    Authors: Teppei Kamada, Hironori Ohdaira, Hideyuki Takeuchi, Junji Takahashi, Rui Marukuchi, Eisaku Ito, Norihiko Suzuki, Satoshi Narihiro, Sojun Hoshimoto, Masashi Yoshida, Mitsuyoshi Urashima and Yutaka Suzuki
    Citation: BMC Gastroenterology 2020 20:354
  35. Eosinophilic gastrointestinal disorders (EGIDs) are a rare group of inflammatory disorders that can occur anywhere along the gastrointestinal tract, from the esophagus to the rectum. In particular, those with ...

    Authors: Ryo Ataka, Hirokazu Tanaka, Shintaro Yagi, Kei Yamane, Kenji Yoshino, Tomoyuki Miyauchi, Tomoaki Yoh, Keiichi Arafuka, Shinichi Fujita, Akihiko Hamada, Bunji Endo and Shinji Uemoto
    Citation: BMC Gastroenterology 2020 20:353
  36. Kawasaki Disease (KD) is the most common paediatric vasculitis affecting small to medium arteries. Although the average age of diagnosis is 3.4 years with a well-defined clinical presentation, older patients w...

    Authors: Krishan Pratap, Logan S. Gardner, David Gillis, Martin Newman, Dana Wainwright and Roger Prentice
    Citation: BMC Gastroenterology 2020 20:352
  37. Early gastric carcinoma is heterogeneous and can be divided into early gastric cardiac carcinoma (EGCC) and early gastric non-cardiac carcinoma (EGNCC) groups. At present, differences in clinicopathology remai...

    Authors: Yaohui Wang, Xiuqing Li, Lili Gao, Chenxi Wang, Yifen Zhang and Qin Huang
    Citation: BMC Gastroenterology 2020 20:351
  38. Hepatolithiasis often leads to atrophy–hypertrophy complex due to bile duct obstruction, inflammation or infection in the affected liver segments and compensatory response in the normal segments. In severe bil...

    Authors: Wei Wang, ZiJie Zhang and Jian Wang
    Citation: BMC Gastroenterology 2020 20:350
  39. Despite promising animal data, there is no randomized controlled trial (RCT) on the effects of high protein (HP)-diet and/or β-cryptoxanthin in non-alcoholic fatty liver disease (NAFLD). Aims: Safety and effic...

    Authors: Fatemeh Haidari, Abdollah Hojhabrimanesh, Bizhan Helli, Seyed-Saeed Seyedian, Kambiz Ahmadi-Angali and Behnaz Abiri
    Citation: BMC Gastroenterology 2020 20:349
  40. Previous studies have demonstrated the benefits of thymosin alpha-1 (Tα1) in anti-virus, immunological enhancement and anti-inflammation. However, it is controversial about the efficacy and safety of entecavir...

    Authors: Dan Peng, Hai-Yan Xing, Chen Li, Xian-Feng Wang, Min Hou, Bin Li and Jian-Hong Chen
    Citation: BMC Gastroenterology 2020 20:348
  41. Vitamin D (VD) is important in hepatic fibrogenesis in animal models and human studies. VD deficiency is associated with liver fibrosis progression. Metabolic dysfunction of the liver, as an intermediate organ...

    Authors: Supachaya Sriphoosanaphan, Kessarin Thanapirom, Sirinporn Suksawatamnuay, Panarat Thaimai, Sukanya Sittisomwong, Kanokwan Sonsiri, Nunthiya Srisoonthorn, Nicha Teeratorn, Nattaporn Tanpowpong, Bundit Chaopathomkul, Sombat Treeprasertsuk, Yong Poovorawan and Piyawat Komolmit
    Citation: BMC Gastroenterology 2020 20:346
  42. Tunneled peritoneal drainage catheters are described as an effective and relatively safe method in the management of malignant and non-malignant refractory ascites. Therapeutic advantages, linked to their use,...

    Authors: Maria Paparoupa, Henning Wege, Anna Creutzfeldt, Marcial Sebode, Faik G. Uzunoglu, Olaf Boenisch, Axel Nierhaus, Jakob R. Izbicki and Stefan Kluge
    Citation: BMC Gastroenterology 2020 20:345
  43. Several genetic variants are known to be associated with nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the longitudinal associations between genetic variants and NAFLD.

    Authors: Goh Eun Chung, Eunsoon Shin, Min-Sun Kwak, Jong In Yang, Jong-Eun Lee, Eun Kyung Choe and Jeong Yoon Yim
    Citation: BMC Gastroenterology 2020 20:344
  44. As with isolated ileitis the findings of nonspecific small bowel enteritis (NSE) on capsule endoscopy (CE) poses a clinical challenge. There is lack of available evidence to help clinicians to predict signific...

    Authors: Sandeep Sihag, Brandon Tan, Serhiy Semenov, Mohd Syafiq Ismail, Barbara Ryan, Anthony O’Connor, Niall Breslin, Rita Douglas and Deirdre McNamara
    Citation: BMC Gastroenterology 2020 20:341
  45. Previous studied revealed that psoriasis and Inflammatory bowel disease (IBD) have highly overlapping epidemiological characteristics, genetic susceptibility loci, disease risk factors, immune mechanisms, and ...

    Authors: Jingyi Ju, Yuanyuan Dai, Jiaolan Yang, Changqin Liu, Li Fan, Lijin Feng, Binghui Zhao, Meiying Zeng, Zhanju Liu and Xiaomin Sun
    Citation: BMC Gastroenterology 2020 20:340

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