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  1. Submucosal oesophageal squamous cell carcinoma is a quite infrequent and special type of oesophageal cancer. Its endoscopic manifestations are similar to those of submucosal oesophageal lesions, so it is easil...

    Authors: Yuting Jia, Quanmao Zhang, Erfeng Li, Zhen Zhang and Xing Chen
    Citation: BMC Gastroenterology 2022 22:97
  2. Portal hypertensive biliopathy (PHB) was caused by anatomical and functional abnormalities in the intrahepatic and extrahepatic bile ducts secondary to portal hypertension. Currently, there is no consensus reg...

    Authors: Ming Zhao, Xiaoze Wang, Bangxi Liu and Xuefeng Luo
    Citation: BMC Gastroenterology 2022 22:96
  3. The current guideline recommends patients who meet high probability criteria for choledocholithiasis to receive endoscopic retrograde cholangiopancreatography (ERCP). However, adverse events can occur during E...

    Authors: Meng-Ying Lin, Chun-Te Lee, Ming-Tsung Hsieh, Ming-Ching Ou, Yao-Shen Wang, Meng-Chieh Lee, Wei-Lun Chang and Bor-Shyang Sheu
    Citation: BMC Gastroenterology 2022 22:94
  4. Mucosal healing (MH) evaluated by endoscopy is a novel target of therapy in UC as it is associated with improved long-term outcomes. It is defined based on the Mayo endoscopic score (MES), but it is still to d...

    Authors: Angelo Viscido, Marco Valvano, Gianpiero Stefanelli, Annalisa Capannolo, Chiara Castellini, Eugenia Onori, Antonio Ciccone, Filippo Vernia and Giovanni Latella
    Citation: BMC Gastroenterology 2022 22:92
  5. Acute adhesion-related small bowel obstruction (ASBO) is a common digestive emergency, accounting for 1 to 3% of all digestive emergencies. The efficacy of conservative management in this setting is a subject ...

    Authors: Charles Sabbagh, Francois Mauvais, Jean-Jacques Tuech, Christophe Tresallet, Pablo Ortega-Debalon, Muriel Mathonnet, Jeremie H. Lefevre, Zaher Lakkis, David Fuks, Fabrice Muscari, Bernard Dron, Philippe Couderc, Arnaud Alves and Jean-Marc Regimbeau
    Citation: BMC Gastroenterology 2022 22:90
  6. Intestinal tuberculosis still has a high incidence, especially in developing countries. The biggest challenge of this disease is the establishment of the diagnosis because the clinical features are not typical...

    Authors: Hasan Maulahela, Marcellus Simadibrata, Erni Juwita Nelwan, Nur Rahadiani, Editha Renesteen, S. W. T. Suwarti and Yunita Windi Anggraini
    Citation: BMC Gastroenterology 2022 22:89
  7. Methylated SDC2 and TFPI2 are widely used for colorectal cancer (CRC) detection. However, they often miss some CRCs, which directly diminishes the sensitivity. Further investigations of the underlying mechanisms ...

    Authors: Ruixue Lei, Yanteng Zhao, Kai Huang, Qian Wang, Kangkang Wan, Tingting Li, Haijun Yang and Xianping Lv
    Citation: BMC Gastroenterology 2022 22:88
  8. Abnormal hypermethylation of the septin 9 gene was an inchoate incident in some cancers. Though latest several researches had paid attention to its value in prognosis, the consequences were not distinctly, esp...

    Authors: Mingliang Huang, Jiehua He, Wei Lai, Lu Liu, Heyang Xu, Yujie Zeng, Qiusheng Lan, Xiangan Lin and Zhonghua Chu
    Citation: BMC Gastroenterology 2022 22:87
  9. Authors: Luca Elli, Donatella Barisani, Valentina Vaira, Maria Teresa Bardella, Matilde Topa, Maurizio Vecchi, Luisa Doneda, Alice Scricciolo, Vincenza Lombardo and Leda Roncoroni
    Citation: BMC Gastroenterology 2022 22:86

    The original article was published in BMC Gastroenterology 2020 20:387

  10. To predict survival time of Korean hepatocellular carcinoma (HCC) patients using multi-center data as a foundation for the development of a predictive artificial intelligence model according to treatment metho...

    Authors: Byeonggwan Noh, Young Mok Park, Yujin Kwon, Chang In Choi, Byung Kwan Choi, Kwang il Seo, Yo-Han Park, Kwangho Yang, Sunju Lee, Taeyoung Ha, YunKyong Hyon and Myunghee Yoon
    Citation: BMC Gastroenterology 2022 22:85
  11. Children in low-resource settings are exposed to multiple risk factors for enteropathogens. However, the probability of exposures may be different across exposure pathways. Accordingly, this study was conducte...

    Authors: Zemichael Gizaw, Alemayehu Worku Yalew, Bikes Destaw Bitew, Jiyoung Lee and Michael Bisesi
    Citation: BMC Gastroenterology 2022 22:84
  12. Endoscopic assessment of disease activity is a key parameter in the management of ulcerative colitis. Whether sigmoidoscopy alone is sufficient to evaluate the disease activity in ulcerative colitis lacks stud...

    Authors: Su Bum Park, Seong-Jung Kim, Jun Lee, Yoo Jin Lee, Dong Hoon Baek, Geom Seog Seo, Eun Soo Kim, Sang-Wook Kim and So Yeong Kim
    Citation: BMC Gastroenterology 2022 22:83
  13. In patients with severe polycystic liver disease (PLD), there is a need for new treatments. Estrogens and possibly other female sex hormones stimulate growth in PLD. In some patients, liver volume decreases af...

    Authors: S. E. Aapkes, L. H. P. Bernts, A. P. van den Berg, M. van den Berg, H. Blokzijl, A. E. P. Cantineau, M. D. A. van Gastel, R. J. de Haas, P. Kappert, R. U. Müller, F. Nevens, R. Torra, A. Visser, J. P. H. Drenth and R. T. Gansevoort
    Citation: BMC Gastroenterology 2022 22:82
  14. The role of Helicobacter pylori (H. pylori) infection in the development of non-alcoholic fatty liver disease (NAFLD) remains controversial. The exact relationship requires further investigation. This study aimed...

    Authors: Weijun Wang, Mengke Fan, Rui Gong, Yurui Zhang, Junchao Zeng, Sanping Xu and Rong Lin
    Citation: BMC Gastroenterology 2022 22:81
  15. Acute-on-chronic liver failure (ACLF) is featured with rapid deterioration of chronic liver disease and poor short-term prognosis. Liver transplantation (LT) is recognized as the curative option for ACLF. Howe...

    Authors: Min Yang, Bo Peng, Quan Zhuang, Junhui Li, Hong Liu, Ke Cheng and Yingzi Ming
    Citation: BMC Gastroenterology 2022 22:80
  16. Colorectal cancer (CRC) consists of several histological subtypes that greatly affect prognosis. Venous invasion (VI) has been implicated in the postoperative recurrence of CRC, but the relationship between th...

    Authors: Yasuo Imai and Masanori Ichinose
    Citation: BMC Gastroenterology 2022 22:79
  17. Heterotopic tumor is a rare disease. Thus far, no cases of heterotopic cholangiocarcinoma have been reported in the world. Cholangiocarcinoma mainly metastasizes by direct invasion, and it can lead to liver me...

    Authors: Chao Wang, Baoyue Zhang, Runmei Peng, Zan Zuo, Hongzhong Cheng, Jun Zhu, Tianxing Chen and Zhengji Song
    Citation: BMC Gastroenterology 2022 22:78
  18. Hepatocellular carcinoma (HCC) was frequently considered as a kind of malignant tumor with a poor prognosis. Cyclin-dependent kinases (CDK) 4 was considered to be cell-cycle-related CDK gene. In this study, ...

    Authors: Zhong-liu Wei, Xin Zhou, Chen-lu Lan, Hua-sheng Huang, Xi-wen Liao, Shu-tian Mo, Yong-guang Wei and Tao Peng
    Citation: BMC Gastroenterology 2022 22:77
  19. Accumulating studies have demonstrated that lncRNAs play vital roles in the prognosis of gastric cancer (GC); however, the prognostic value of N6-methyladenosine-related lncRNAs has not been fully reported in ...

    Authors: Jun-Mei Wang, Xuan Li, Peng Yang, Wen-Bin Geng and Xiao-Yong Wang
    Citation: BMC Gastroenterology 2022 22:76
  20. Colorectal juvenile polyps are rare and generally considered benign in adults. Carcinogenesis or neoplastic changes are rarely mentioned in the literature. We systematically evaluated the characteristics and p...

    Authors: Jie Dong, Tian-Shi Ma, Yuan-Hong Xu, Peng Li, Wan-Yuan Chen, Jiang-Feng Tu and You-Wei Chen
    Citation: BMC Gastroenterology 2022 22:75
  21. Intrabolus pressure (IBP) recorded by high-resolution manometry (HRM) portrays the compartmentalized force on a bolus during esophageal peristalsis. HRM may be a reliable screening tool for esophageal dysmotil...

    Authors: Katelyn E. Madigan, J. Shawn Smith, Joni K. Evans and Steven B. Clayton
    Citation: BMC Gastroenterology 2022 22:74
  22. Irritable Bowel Syndrome (IBS) is a highly prevalent functional gastrointestinal disorder. Earlier studies have shown that IBS can limit the ability to perform at work and lead to absenteeism. However, few stu...

    Authors: Åsa Frändemark, Hans Törnblom, Magnus Simrén and Sofie Jakobsson
    Citation: BMC Gastroenterology 2022 22:73
  23. Inflammatory bowel disease (IBD) treatment paradigms recommend objective disease activity assessment and reactive therapeutic drug monitoring (TDM) prior to changes in biologic therapy. We aimed to describe ob...

    Authors: Benjamin Click, Edward L. Barnes, Benjamin L. Cohen, Bruce E. Sands, John S. Hanson, David T. Rubin, Marla C. Dubinsky, Miguel Regueiro, Derek Gazis, Julie M. Crawford and Millie D. Long
    Citation: BMC Gastroenterology 2022 22:71
  24. Gastric polyps (GPs) are usually asymptomatic lesions of the upper gastrointestinal tract observed in 1–3% of esophagogastroduodenoscopies (EGD). Most GPs are benign. The aim of this study was to precise the f...

    Authors: Haythem Yacoub, Norsaf Bibani, Mériam Sabbah, Nawel Bellil, Asma Ouakaa, Dorra Trad and Dalila Gargouri
    Citation: BMC Gastroenterology 2022 22:70
  25. Serum pepsinogen (PG) is recommended as a screening test for premalignant gastric lesions. However, real-world evidence demonstrating its applicability and equivalence between different test brands is limited.

    Authors: Tsung-Hsien Chiang, Yen-Nien Chen, Yi-Ru Chen, Yu-Hua Tseng, Chun-Fu Shieh, Cheng-Ying Liu, Han-Mo Chiu, Hung Chiang, Chia-Tung Shun, Ming-Shiang Wu, Jaw-Town Lin and Yi-Chia Lee
    Citation: BMC Gastroenterology 2022 22:69
  26. Skin metastases from colorectal adenocarcinoma are rare conditions that are metachronous in most of cases and may represent the first sign of a recurrence. These lesions are usually located to the abdominal wa...

    Authors: A. Picciariello, G. Tomasicchio, G. Lantone, G. Martines, R. Dibra, G. Trigiante, A. d’Amati, D. Piscitelli and D. F. Altomare
    Citation: BMC Gastroenterology 2022 22:68
  27. Upper gastrointestinal (GI) bleeding is a severe acute disease of gastroenterology department. Fish bone is the most common food-related foreign body. However, fish bone piercing the esophagus, causing the med...

    Authors: Zhiqiang Yi, Cheng Chen, Biguang Tuo, Taolang Li and Xuemei Liu
    Citation: BMC Gastroenterology 2022 22:67
  28. Physical inactivity and sarcopenia are two important predictors associated with increased morbidity and mortality in patients with cirrhosis. At present, the benefit of a home-based exercise training program i...

    Authors: Pavapol Sirisunhirun, Wimolrak Bandidniyamanon, Yonworanat Jrerattakon, Kobkun Muangsomboon, Pornpoj Pramyothin, Supot Nimanong, Tawesak Tanwandee, Phunchai Charatcharoenwitthaya, Siwaporn Chainuvati and Watcharasak Chotiyaputta
    Citation: BMC Gastroenterology 2022 22:66
  29. Synchronous peritoneal metastasis of colorectal cancer usually predicts a bleak prognosis. Hyperthermic intraperitoneal chemotherapy (HIPEC) and cytoreductive surgery (CRS) have brought a glimmer of hope to th...

    Authors: Peilin Dai, Zaisheng Ye, Zhai Cai, Zeyu Luo, Enming Qiu, Yu Lin, Jian Cai, Hui Wang, Zhou Li and Shuai Han
    Citation: BMC Gastroenterology 2022 22:65
  30. Peptic ulcer bleeding remains a typical medical emergency with significant morbidity and mortality. Peptic ulcer rebleeding often occurs within three days after emergent endoscopic hemostasis. Our study aims t...

    Authors: Yongkang Lai, Yuling Xu, Zhenhua Zhu, Xiaolin Pan, Shunhua Long, Wangdi Liao, Bimin Li, Yin Zhu, Youxiang Chen and Xu Shu
    Citation: BMC Gastroenterology 2022 22:64
  31. An increasing number of studies have shown the merits of endoscopic retrograde appendicitis therapy (ERAT) in diagnosing and treating acute uncomplicated appendicitis. However, no related prospective controlle...

    Authors: Zhemin Shen, Peilong Sun, Miao Jiang, Zili Zhen, Jingtian Liu, Mu Ye and Weida Huang
    Citation: BMC Gastroenterology 2022 22:63
  32. The pathogenesis of ulcerative colitis (UC) is closely related to the gut microbiota. Moxibustion has been used to improve the inflammation and gastrointestinal dysfunctions in gastrointestinal disorders such ...

    Authors: Qin Qi, Ya-Nan Liu, Si-Yi Lv, Huan-Gan Wu, Lin-Shuang Zhang, Zhan Cao, Hui-Rong Liu, Xiao-Mei Wang and Lu-Yi Wu
    Citation: BMC Gastroenterology 2022 22:62
  33. The purpose of this study was to investigate the diagnosis and treatment experience of traumatic duodenal ruptures in children.

    Authors: Yuanyuan Luo, Xiaobing He, Lanlan Geng, Runxian Ouyang, Yingyi Xu, Yufeng Liang, Jinhui Wu, Hong Zhang, Zhihua Ye, Rongjun Zou, Qiang Wu and Chengwei Chai
    Citation: BMC Gastroenterology 2022 22:61
  34. Stricturing gastrointestinal tuberculosis (GITB) may result in persistent symptoms even after antitubercular therapy (ATT) and may require surgical intervention. Data on efficacy and safety of endoscopic dilat...

    Authors: Pankaj Kumar, Anuraag Jena, Chhagan Lal Birda, Harjeet Singh, Pankaj Gupta, Kaushal Kishor Prasad, Usha Dutta and Vishal Sharma
    Citation: BMC Gastroenterology 2022 22:60
  35. Liver injury related to Graves’ Disease (GD) includes hepatotoxicity of thyroid hormone excess, drug-induced liver injury, and changes resulting from concomitant liver disease. Methimazole (MMI) has been shown...

    Authors: Meifang Zheng, Shiyuan Cui, Wei Zhang, David R. Brigstock and Runping Gao
    Citation: BMC Gastroenterology 2022 22:59
  36. Peptic ulcer disease (PUD) is a common digestive disorder, of which the prevalence decreased in the past few decades. However, the decreasing tendency has plateaued in recent years due to changes in risk facto...

    Authors: Xin Xie, Kaijie Ren, Zhangjian Zhou, Chengxue Dang and Hao Zhang
    Citation: BMC Gastroenterology 2022 22:58
  37. Rectal adenocarcinoma is one of major public health problems, severely threatening people’s health and life. Cox proportional hazard models have been applied in previous studies widely to analyze survival data...

    Authors: Xu Zhang, Fengshuo Xu, Yadi Bin, Tianjie Liu, Zhichao Li, Dan Guo, Yarui Li, Qiao Huang, Jun Lyu and Shuixiang He
    Citation: BMC Gastroenterology 2022 22:57
  38. Type 2 isolated dextrogastria in conjunction with protrusion of the right hemidiaphragm and hiatal hernia is an uncommon anomaly among all transpositions of the viscera. Clear diagnosis is not straightforward ...

    Authors: Shahid Aziz, Simone König, Haseeb Noor, Muhammad Nadeem, Rabaab Zahra and Faisal Rasheed
    Citation: BMC Gastroenterology 2022 22:56
  39. Liver cirrhosis is a well-known risk factor of sepsis after emergent gastrointestinal (GI) endoscopy. Elective GI endoscopy before living donor liver transplantation (LDLT), however, may also carry the septic ...

    Authors: Yi-Chia Chan, Chao-Long Chen, Chih-Chi Wang, Chih-Che Lin, Chee-Chien Yong, King-Wah Chiu and Keng-Liang Wu
    Citation: BMC Gastroenterology 2022 22:54
  40. Congenital portosystemic shunts (CPSS) are rare vascular malformations and can be classified into extrahepatic and intrahepatic shunts. Extrahepatic CPSS, also termed Abernethy malformations are associated wit...

    Authors: Ludger Sieverding, Michael Hofbeck, Jörg Michel, Andreas Hornung, Christian Scheckenbach, Gerd Grözinger, Ekkehard Sturm, Steven W. Warmann and Anja Hanser
    Citation: BMC Gastroenterology 2022 22:53
  41. Juxta-papillary duodenal diverticulum (JPDD) has been associated with obstructive jaundice and ascending cholangitis. Potential mechanisms include periampullary colonization of pathogenic bacteria and mechanic...

    Authors: Uday Shankar, Priyanka Bhandari, Ankur Panchal, David Weeks, Helen Wu, Fufei Chen, Narinder Maheshwari, Raghav Bansal, Aaron Walfish, Joel Baum, Priya A. Jamidar and Joshua Aron
    Citation: BMC Gastroenterology 2022 22:52
  42. Postoperative pancreatic fistula (POPF) is a frequent complication after pancreaticoduodenectomy (PD). This study aimed to investigate the impact of Vater’s ampullary carcinoma (VAC) on clinically relevant POP...

    Authors: Yifei Yang, Xu Fu, Saisai Zhu, Zhenghua Cai, Yudong Qiu and Liang Mao
    Citation: BMC Gastroenterology 2022 22:51
  43. Fewer than 50% of patients with acute-on-chronic liver failure (ACLF) recover spontaneously, and ACLF has high mortality without liver transplantation. Oxidative stress has been shown to mediate hepatic inflam...

    Authors: Zhen Tian, Naijuan Yao, Yuchao Wu, Fei Wang and Yingren Zhao
    Citation: BMC Gastroenterology 2022 22:50
  44. Previous studies have shown that tumor mutation burden (TMB) in cancer is associated with prognosis. The purpose of this study is to identify TMB related genes in gastric cancer (GC) and to explore their progn...

    Authors: Wenjie Li, Kezhi Zhou, Mengting Li, Qian Hu, Wanhui Wei, Lan Liu and Qiu Zhao
    Citation: BMC Gastroenterology 2022 22:45

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