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  1. Content type: Research article

    In patients with common bile duct stones (CBDS) and intact gallbladder, further management for the gallbladder after the CBDS clearance is still controversial. The relationship between gallbladder motility and...

    Authors: Tzung-Jiun Tsai, Hoi-Hung Chan, Kwok-Hung Lai, Chih-An Shih, Sung-Shuo Kao, Wei-Chih Sun, E-Ming Wang, Wei-Lun Tsai, Kung-Hung Lin, Hsien-Chung Yu, Wen-Chi Chen, Huay-Min Wang, Feng-Woei Tsay, Huey-Shyan Lin, Jin-Shiung Cheng and Ping-I Hsu

    Citation: BMC Gastroenterology 2018 18:32

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  2. Content type: Research article

    Cyclooxygenase (COX) activity is increased in endoscopic normal colonic mucosa from patients with colorectal neoplasia (CRN). COX-2 is thought to be the predominant COX isozyme involved in neoplasia. Meanwhile...

    Authors: Thorbjørn Søren Rønn Jensen, Badar Mahmood, Morten Bach Damm, Marie Balslev Backe, Mattias Salling Dahllöf, Steen Seier Poulsen, Mark Berner Hansen and Niels Bindslev

    Citation: BMC Gastroenterology 2018 18:31

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  3. Content type: Research article

    Chronic abdominal pain is a common worldwide problem and known to be associated with psychological problems. This study evaluated the association between abdominal pain-predominant functional gastrointestinal ...

    Authors: Nishadi Ranasinghe, Niranga Manjuri Devanarayana, Shaman Rajindrajith, Madusanka S. Perera, Samudu Nishanthinie, Tania Warnakulasuriya and Piyanjali Thamesha de Zoysa

    Citation: BMC Gastroenterology 2018 18:33

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  4. Content type: Research article

    Geranylgeranylacetone (GGA), an anti-ulcer drug widely used in Japan, has attracted interest because of its various therapeutic effects. Therefore, we investigated the effects of GGA on human hepatic stellate ...

    Authors: Takemasa Senoo, Ryu Sasaki, Yuko Akazawa, Tatsuki Ichikawa, Satoshi Miuma, Hisamitsu Miyaaki, Naota Taura and Kazuhiko Nakao

    Citation: BMC Gastroenterology 2018 18:34

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  5. Content type: Research article

    Endoscopic submucosal dissection (ESD) is a standard treatment for early gastric cancer. A new multi-functional ESD device was developed to achieve complete ESD with a single device. A metal plate attached to ...

    Authors: Mitsuru Esaki, Sho Suzuki, Yasuyo Hayashi, Azusa Yokoyama, Shuichi Abe, Taizo Hosokawa, Haruei Ogino, Hirotada Akiho, Eikichi Ihara and Yoshihiro Ogawa

    Citation: BMC Gastroenterology 2018 18:35

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  6. Content type: Research article

    Anal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for overall survival. The aim of this study was to evalu...

    Authors: Paulo C. Soares, Eliana S. Abdelhay, Luiz Claudio S. Thuler, Bruno Moreira Soares, Samia Demachki, Gessica Valéria Rocha Ferro, Paulo P. Assumpção, Leticia Martins Lamarão, Luis Felipe Ribeiro Pinto and Rommel Mario Rodríguez Burbano

    Citation: BMC Gastroenterology 2018 18:30

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  7. Content type: Study protocol

    Of all older patients that opt for elective colorectal surgery, approximately one-third has one or more postoperative complications, particularly those patients with a low cardiorespiratory fitness (ventilator...

    Authors: Annefleur E. M. Berkel, Bart C. Bongers, Marie-Janne S. van Kamp, Hayke Kotte, Paul Weltevreden, Frans H. C. de Jongh, Michiel M. M. Eijsvogel, A. N. Machteld Wymenga, Marloes Bigirwamungu-Bargeman, Job van der Palen, Marc J. van Det, Nico L. U. van Meeteren and Joost M. Klaase

    Citation: BMC Gastroenterology 2018 18:29

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  8. Content type: Research article

    Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence o...

    Authors: Stian Magnus Staurung Orlien, Nejib Yusuf Ismael, Tekabe Abdosh Ahmed, Nega Berhe, Trine Lauritzen, Borghild Roald, Robert David Goldin, Kathrine Stene-Johansen, Anne Margarita Dyrhol-Riise, Svein Gunnar Gundersen, Marsha Yvonne Morgan and Asgeir Johannessen

    Citation: BMC Gastroenterology 2018 18:27

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  9. Content type: Research article

    The primary function of the intestines is the absorption of water and nutrients. Although our knowledge about these processes on the cellular level is extensive, a number of important intracellular elements re...

    Authors: Satu Oltedal, Ivar Skaland, Jodi Maple-Grødem, Kjersti Tjensvoll, Emiel A. M. Janssen, Bjørnar Gilje, Rune Smaaland, Reino Heikkilä and Oddmund Nordgård

    Citation: BMC Gastroenterology 2018 18:26

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  10. Content type: Research article

    It has been reported that some single-nucleotide polymorphisms (SNPs) in lipid regulators such as apolipoproteins and cell surface molecules for hepatitis C virus (HCV) entry into hepatocytes are associated wi...

    Authors: Rie Harada, Masako Kimura, Yasushi Sato, Tatsuya Taniguchi, Tetsu Tomonari, Takahiro Tanaka, Hironori Tanaka, Naoki Muguruma, Hirohiko Shinomiya, Hirohito Honda, Issei Imoto, Masahiro Sogabe, Toshiya Okahisa and Tetsuji Takayama

    Citation: BMC Gastroenterology 2018 18:24

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  11. Content type: Research article

    Serum IgG and IgA food antibodies have been used for dietary advice to subjects with gastrointestinal symptoms and perceived food intolerance, but the role of these antibodies in mediating intolerance is contr...

    Authors: Anne Stine Kvehaugen, Dag Tveiten and Per G. Farup

    Citation: BMC Gastroenterology 2018 18:22

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  12. Content type: Research article

    Accelerated treatment strategy, including tight disease control and early aggressive therapy with immunosuppressives (IS) and biological agents have become increasingly common in inflammatory bowel disease (IB...

    Authors: Zsuzsanna Kurti, Akos Ilias, Lorant Gonczi, Zsuzsanna Vegh, Petra Fadgyas-Freyler, Gyula Korponay, Petra A. Golovics, Barbara D. Lovasz and Peter L. Lakatos

    Citation: BMC Gastroenterology 2018 18:23

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  13. Content type: Research article

    Although subacute and chronic gastrointestinal symptoms are very common in primary care, epidemiological date are sparse. The aim of the study was to examine and quantify the prevalence of subacute and chronic...

    Authors: Maria Avramidou, Felix Angst, Jules Angst, André Aeschlimann, Wulf Rössler and Ulrich Schnyder

    Citation: BMC Gastroenterology 2018 18:21

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  14. Content type: Research article

    The gastric microbiota has recently been implicated in the causation of organic/structural gastroduodenal diseases (gastric and duodenal ulcers, gastric cancer) in patients with Helicobacter pylori (H. pylori) in...

    Authors: Verima Pereira, Philip Abraham, Sivaramaiah Nallapeta and Anjali Shetty

    Citation: BMC Gastroenterology 2018 18:20

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  15. Content type: Research article

    Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) predict severity in various diseases. In this study, we evaluated the value of NLR and PLR as prognostic factors in acute pancreatiti...

    Authors: Seung Kook Cho, Saehyun Jung, Kyong Joo Lee and Jae Woo Kim

    Citation: BMC Gastroenterology 2018 18:18

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  16. Content type: Research article

    Peripheral neuropathy is one most common, limiting and invalidating neurological symptom in subjects with hepatitis C virus and mixed cryoglobulinemia. Notably, the medical therapy proposed to eradicate HCV, c...

    Authors: Rita Moretti, Paola Caruso, Matteo Dal Ben, Silvia Gazzin and Claudio Tiribelli

    Citation: BMC Gastroenterology 2018 18:19

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  17. Content type: Research article

    Compliance with a gluten-free diet (GFD) is difficult at all ages but particularly for teenagers due to social, cultural, economic, and practical pressures. The multidisciplinary team responsible for the treat...

    Authors: Maraci Rodrigues, Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro

    Citation: BMC Gastroenterology 2018 18:15

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    The Correction to this article has been published in BMC Gastroenterology 2018 18:36

  18. Content type: Case report

    We present the first description of en bloc endoscopic submucosal dissection (ESD) for total circumferential Barrett’s adenocarcinoma, predominantly of the long-segment Barrett’s esophagus (LSBE), with a 2-year f...

    Authors: Miki Kaneko, Akira Mitoro, Motoyuki Yoshida, Masayoshi Sawai, Yasushi Okura, Masanori Furukawa, Tadashi Namisaki, Kei Moriya, Takemi Akahane, Hideto Kawaratani, Mitsuteru Kitade, Kousuke Kaji, Hiroaki Takaya, Yasuhiko Sawada, Kenichiro Seki, Shinya Sato…

    Citation: BMC Gastroenterology 2018 18:16

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  19. Content type: Research article

    Endoscopic retrograde cholangiography using a short double-balloon endoscope (DB-ERC) is a promising minimally-invasive method for accessing hepaticojejunostomy (HJ) anastomosis in patients with surgically alt...

    Authors: Sho Mizukawa, Koichiro Tsutsumi, Hironari Kato, Shinichiro Muro, Yutaka Akimoto, Daisuke Uchida, Kazuyuki Matsumoto, Takeshi Tomoda, Shigeru Horiguchi and Hiroyuki Okada

    Citation: BMC Gastroenterology 2018 18:14

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  20. Content type: Research article

    Dyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The...

    Authors: Abdurahaman Seid, Zemenu Tamir and Wondmagegn Demsiss

    Citation: BMC Gastroenterology 2018 18:13

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  21. Content type: Research article

    Slingshot homolog-1 (SSH1) plays an important role in pathological processes, including in the occurrence and development of tumours. The purpose of this study was to determine whether SSH1 is a key biomarker ...

    Authors: Yusufu Maimaiti, Maimaitiaili Maimaitiming, Yiliang Li, Saifuding Aibibula, Azatijiang Ainiwaer, Aikebaier Aili, Zhenzhu Sun and Kelimu Abudureyimu

    Citation: BMC Gastroenterology 2018 18:12

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  22. Content type: Research article

    Nutrition support is a common means for patients with gastric cancer, especially for those undergoing elective surgery. Recently, enteral immunonutrition (EIN) was increasingly found to be more effective than ...

    Authors: Ying Cheng, Junfeng Zhang, Liwei Zhang, Juan Wu and Zhen Zhan

    Citation: BMC Gastroenterology 2018 18:11

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  23. Content type: Research article

    Different clinical behaviour influences the importance of differentiating focal nodular hyperplasia (FNH) from other focal liver lesions (FLLs). The aim of this study was to compare the efficacy of contrast-en...

    Authors: Tomasz K. Nowicki, Karolina Markiet, Ewa Izycka-Swieszewska, Katarzyna Dziadziuszko, Michal Studniarek and Edyta Szurowska

    Citation: BMC Gastroenterology 2018 18:10

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  24. Content type: Case report

    Mesenteric inflammatory veno-occlusive disease (MIVOD) is difficult to diagnose because of its rarity, nonspecific clinical findings, and frequent confusion with other diseases including inflammatory bowel dis...

    Authors: Yosuke Yamada, Ken Sugimoto, Yashiro Yoshizawa, Yoshifumi Arai, Yoshiro Otsuki, Tomio Arai, Yasuyuki Kobayashi, Yoshihiko Sato and Yoshisuke Hosoda

    Citation: BMC Gastroenterology 2018 18:9

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  25. Content type: Research article

    Gastroesophageal reflux disease (GERD) is a factor that has a significant negative impact on the quality of life (QoL). Vertebral fractures and/or spinal malalignment may influence the frequency of GERD. Howev...

    Authors: Tetsuro Ohba, Shigeto Ebata, Kensuke Koyama and Hirotaka Haro

    Citation: BMC Gastroenterology 2018 18:8

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  26. Content type: Research article

    The risk of Hepatitis B virus (HBV) reactivation in patients with different hematological malignancy except lymphoma were rarely known before.

    Authors: Chien-Yuan Chen, Feng-Ming Tien, Aristine Cheng, Shang-Yi Huang, Wen-Chien Chou, Ming Yao, Jih-Luh Tang, Hwei-Fang Tien and Wang-Huei Sheng

    Citation: BMC Gastroenterology 2018 18:6

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  27. Content type: Research article

    Colonoscopy plays crucial role in the establishment of the diagnosis, management and follow-up of ulcerative colitis (UC). None of the currently widely used endoscopic scores consider disease extent, and there...

    Authors: Anita Bálint, Klaudia Farkas, Zoltán Szepes, Ferenc Nagy, Mónika Szűcs, László Tiszlavicz, Renáta Bor, Ágnes Milassin, Mariann Rutka, Anna Fábián and Tamás Molnár

    Citation: BMC Gastroenterology 2018 18:7

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  28. Content type: Research article

    Ramosetron is a potent and selective serotonin type 3 receptor antagonist. This meta-analysis aimed to analyze the efficacy and safety of ramosetron for irritable bowel syndrome with diarrhea (IBS-D).

    Authors: Qingqing Qi, Yan Zhang, Feixue Chen, Xiuli Zuo and Yanqing Li

    Citation: BMC Gastroenterology 2018 18:5

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  29. Content type: Correction

    Unfortunately, the original article [1] contained an error incorporated during production. A duplicated version of Table 1 was published in place of Table 2. Table 2 has been corrected in the original article ...

    Authors: Wataru Shibata, Soichiro Sue, Sachiko Tsumura, Yasuaki Ishii, Takeshi Sato, Eri Kameta, Makoto Sugimori, Hiroaki Yamada, Hiroaki Kaneko, Tomohiko Sasaki, Tomohiro Ishii, Toshihide Tamura, Masaaki Kondo and Shin Maeda

    Citation: BMC Gastroenterology 2018 18:4

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    The original article was published in BMC Gastroenterology 2017 17:145

  30. Content type: Research article

    Elevation of the transcription factor HIF-1 is a prominent mediator of not only processes that accompany hypoxia, but also the tumor microenvironment and tissue regeneration. This study uses mediators of “chem...

    Authors: K. M. DiGuilio, M. C. Valenzano, E. Rybakovsky and J. M. Mullin

    Citation: BMC Gastroenterology 2018 18:2

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  31. Content type: Research article

    Pathogenesis in non-alcoholic steatohepatitis (NASH) involves abnormal cholesterol metabolism and hepatic accumulation of toxic free cholesterol. Apical sodium-dependent bile acid transporter (ASBT) inhibition...

    Authors: Renger G. Tiessen, Ciara A. Kennedy, Bradley T. Keller, Nancy Levin, Lisette Acevedo, Bronislava Gedulin, Andre A. van Vliet, Alejandro Dorenbaum and Melissa Palmer

    Citation: BMC Gastroenterology 2018 18:3

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  32. Content type: Case report

    The burden of disease caused by Streptococcus agalactiae has increased significantly among older adults in the last decades. Group B streptococcus infection can be associated with invasive disease and severe clin...

    Authors: Pietro Achilli, Angelo Guttadauro, Paolo Bonfanti, Sabina Terragni, Luca Fumagalli, Ugo Cioffi, Francesco Gabrielli, Matilde De Simone and Marco Chiarelli

    Citation: BMC Gastroenterology 2017 17:170

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  33. Content type: Research article

    It is essential to accurately predict Postoperative liver failure (PHLF) which is a life-threatening complication. Liver hardness measurement (LSM) is widely used in non-invasive assessment of liver fibrosis. ...

    Authors: Jie-wen Lei, Xiao-yu Ji, Jun-feng Hong, Wan-bin Li, Yan Chen, Yan Pan and Jia Guo

    Citation: BMC Gastroenterology 2017 17:171

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  34. Content type: Research article

    Chemokines/cytokines play important roles in the pathogenesis of chronic hepatitis C (CHC). However, their clinical characteristics and implications in treatment responses to pegylated interferon plus ribaviri...

    Authors: Chia-Chen Lin, Shih-Huan Su, Wen-Juei Jeng, Chien-Hao Huang, Wei Teng, Wei-Ting Chen, Yi-Cheng Chen, Chun-Yen Lin and I-Shyan Sheen

    Citation: BMC Gastroenterology 2017 17:169

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  35. Content type: Review

    Hepatitis B virus (HBV) chronic infection affects up to 240 million people in the world and it is a common cause of cirrhosis and hepatocellular carcinoma (HCC). HBV covalently closed circular DNA (cccDNA) pla...

    Authors: Sonia Alonso, Adriana-René Guerra, Lourdes Carreira, Juan-Ángel Ferrer, María-Luisa Gutiérrez and Conrado M. Fernandez-Rodriguez

    Citation: BMC Gastroenterology 2017 17:168

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  36. Content type: Research article

    Upper gastrointestinal bleeding (UGIB) is a common gastrointestinal emergency, which is potentially fatal. Proper management of UGIB requires risk-stratification of patients which can guide the type and aggres...

    Authors: Sibtain M. Moledina and Ewaldo Komba

    Citation: BMC Gastroenterology 2017 17:165

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  37. Content type: Research article

    Increasing attention is focused on the relationship of inflammation biomarkers with malignant tumors. The purpose of the present study was to detect whether the preoperative the red distribution width (RDW) an...

    Authors: Shiqing Cheng, Fuyan Han, Yong Wang, Yanqiu Xu, Teng Qu, Ying Ju and Zhiming Lu

    Citation: BMC Gastroenterology 2017 17:163

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  38. Content type: Case report

    Extramedullary plasmacytoma is a very rare tumor derived from plasma cells and found outside the bone marrow. Most have been identified in patients with the more aggressive anaplastic form of the disease. Only...

    Authors: Tao Lu, Hong Pu and Gaoping Zhao

    Citation: BMC Gastroenterology 2017 17:167

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  39. Content type: Study protocol

    The number of bariatric interventions for morbid obesity is increasing worldwide. Rapid weight loss is a major risk factor for gallstone development. Approximately 11 % of patients who underwent Roux-en-Y gast...

    Authors: Thomas C. C. Boerlage, Sylke Haal, L. Maurits de Brauw, Yair I. Z. Acherman, Sjoerd Bruin, Arnold W. J. M. van de Laar, Daan E. Moes, Bart A. van Wagensveld, Claire E. E. de Vries, Ruben van Veen, Ruben Schouten, Marcel G. Dijkgraaf, Paul Fockens, Victor E. A. Gerdes and Rogier P. Voermans

    Citation: BMC Gastroenterology 2017 17:164

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  40. Content type: Research article

    To assess the feasibility of noninvasive and quantitative evaluation of hepatic pathophysiological changes in rabbit hepatic warm ischemia-reperfusion injury (WIRI) models by using intravoxel incoherent motion...

    Authors: Qian Ji, Zhi Qiang Chu, Tao Ren, Shi Chao Xu, Long Jiang Zhang, Wen Shen and Guang Ming Lu

    Citation: BMC Gastroenterology 2017 17:161

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  41. Content type: Research article

    In recent years, there has been growing concern about the overuse of colonoscopy (CC). Our objective was to evaluate the incidence rate and cumulative probability of having a potentially inadequate CC (PI-CC, ...

    Authors: Santiago Esteban, Ricardo Ricci, Sergio Terrasa and Karin Kopitowski

    Citation: BMC Gastroenterology 2017 17:162

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  42. Content type: Research article

    Children and adolescents with inflammatory bowel disease (IBD) report impairments in daily activities, social interactions and coping. Findings regarding psychological functioning are inconsistent, while limit...

    Authors: Laura Mählmann, Markus Gerber, Raoul I. Furlano, Corinne Legeret, Nadeem Kalak, Edith Holsboer-Trachsler and Serge Brand

    Citation: BMC Gastroenterology 2017 17:160

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  43. Content type: Research article

    Risk scoring systems are used to evaluate patients with upper gastrointestinal bleeding (UGIB). We compared Glasgow-Blatchford score (GBS), modified GBS (mGBS), and Pre-endoscopy Rockall score (Pre-E RS) for i...

    Authors: Il-Gyu Ko, Sung-Eun Kim, Bok Soon Chang, Min Seob Kwak, Jin Young Yoon, Jae Myung Cha, Hyun Phil Shin, Joung Il Lee, Sang Hyun Kim, Jin Hee Han and Jung Won Jeon

    Citation: BMC Gastroenterology 2017 17:159

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  44. Content type: Research article

    Serrated adenocarcinoma (SAC) is a distinct colorectal carcinoma variant that accounts for approximately 7.5% of all advanced colorectal carcinomas. While its prognosis is worse than conventional carcinoma, it...

    Authors: Daiki Hirano, Shiro Oka, Shinji Tanaka, Kyoku Sumimoto, Yuki Ninomiya, Yuzuru Tamaru, Kenjiro Shigita, Nana Hayashi, Yuji Urabe, Yasuhiko Kitadai, Fumio Shimamoto, Koji Arihiro and Kazuaki Chayama

    Citation: BMC Gastroenterology 2017 17:158

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  45. Content type: Research article

    The only treatment for celiac disease (CeD) is a lifelong gluten-free diet (GFD). The restrictive nature of the GFD makes adherence a challenge. As an integral part of CeD management, multiple professional org...

    Authors: Jacob J. Hughey, Bonnie K. Ray, Anne R. Lee, Kristin N. Voorhees, Ciaran P. Kelly and Detlef Schuppan

    Citation: BMC Gastroenterology 2017 17:156

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