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  1. Gastroparesis, a condition of abnormal gastric emptying, is most commonly observed in diabetic women. To date, the role of ovarian hormones and/or gastric hormone receptors on regulating nitrergic-mediated gas...

    Authors: Jeremy Sprouse, Chethan Sampath and Pandu R. Gangula

    Citation: BMC Gastroenterology 2020 20:313

    Content type: Research article

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  2. Underwater endoscopic mucosal resection (UEMR) is a recently developed technique and can be performed during water-aided or ordinary colonoscopy for the treatment of colorectal polyps. The objective of this cl...

    Authors: Zhixin Zhang, Yonghong Xia, Hongyao Cui, Xin Yuan, Chunnian Wang, Jiarong Xie, Yarong Tong, Weihong Wang and Lei Xu

    Citation: BMC Gastroenterology 2020 20:311

    Content type: Research article

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  3. We investigated whether duodenal major papilla morphology could be a risk factor for failure of selective biliary cannulation (SBC) and post endoscopic retrograde cholangiography and pancreatography (ERCP) com...

    Authors: Po-Han Chen, Chun-Fang Tung, Yen-Chung Peng, Hong-Zen Yeh, Chi-Sen Chang and Chia-Chang Chen

    Citation: BMC Gastroenterology 2020 20:310

    Content type: Research article

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  4. Delayed post-polypectomy bleeding (PPB) is a major complication of polypectomy. The effect of prophylactic hemoclipping on delayed PPB is uncertain. The aim of this study was to evaluate the effectiveness of p...

    Authors: Chun-Wei Chen, Chia-Jung Kuo, Cheng-Tang Chiu, Ming-Yao Su, Chun-Jung Lin, Puo-Hsien Le, Siew-Na Lim, Chau-Ting Yeh, Malcolm R. Alison and Wey-Ran Lin

    Citation: BMC Gastroenterology 2020 20:309

    Content type: Research article

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  5. Infantile liver failure syndrome-2 (ILFS2) is caused by neuroblastoma amplified sequence (NBAS) mutation. The disease is characterized by recurrent episodes of acute liver failure (ALF) or by liver crisis trig...

    Authors: Weiran Li, Yu Zhu, Qin Guo and Chaomin Wan

    Citation: BMC Gastroenterology 2020 20:308

    Content type: Case report

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  6. Inflammatory bowel diseases are classic polygenic disorders, with genetic loads that reflect immunopathological processes in response to the intestinal microbiota. Herein we performed the multiomics analysis b...

    Authors: Filip Ambrozkiewicz, Jakub Karczmarski, Maria Kulecka, Agnieszka Paziewska, Magdalena Niemira, Natalia Zeber-Lubecka, Edyta Zagorowicz, Adam Kretowski and Jerzy Ostrowski

    Citation: BMC Gastroenterology 2020 20:307

    Content type: Research article

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  8. Hepatitis B infection is a significant worldwide health issue, predispose to the development of liver cirrhosis and hepatocellular carcinoma. Entecavir is a potent oral antiviral agent of high genetic barrier ...

    Authors: Xiong Khee Cheong, Zhiqin Wong, Norazirah Md Nor and Bang Rom Lee

    Citation: BMC Gastroenterology 2020 20:305

    Content type: Case report

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  9. There are only 6 cases of intraductal papillary mucinous neoplasm (IPMN) complicated with intraductal hemorrhage have been reported in English literatures. All these 6 cases of IPMN occurred in the old people....

    Authors: Jianman Wu, Yin Lin and Jingwen Wu

    Citation: BMC Gastroenterology 2020 20:304

    Content type: Case report

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  10. We experienced a rare case of intraductal papillary mucinous neoplasm arising from Santorini’s duct (SD) forming a tumor protruding into the duodenum .

    Authors: Haruna Komatsubara, Hiroyuki Kato, Daisuke Noguchi, Kazuyuki Gyoten, Aoi Hayasaki, Yusuke Iizawa, Takehiro Fujii, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Hiroyuki Sakurai and Shugo Mizuno

    Citation: BMC Gastroenterology 2020 20:303

    Content type: Case report

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  11. We examined how extra-hepatic comorbidity burden impacts mortality in patients with cirrhosis referred for liver transplantation (LT).

    Authors: Scott Coppel, Karan Mathur, Burcin Ekser, Kavish R. Patidar, Eric Orman, Archita P. Desai, Eduardo Vilar-Gomez, Chandrashekhar Kubal, Naga Chalasani, Lauren Nephew and Marwan Ghabril

    Citation: BMC Gastroenterology 2020 20:302

    Content type: Research article

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  12. Systemic inflammatory response is closely related to the development and prognosis of liver failure. This study aimed to establish a new model combing the inflammatory markers including neutrophil/lymphocyte r...

    Authors: Li Qiang, Jiao Qin, Changfeng Sun, Yunjian Sheng, Wen Chen, Bangdong Qiu, Xin Chen, Yuanfang Chen, Fei Liu and Gang Wu

    Citation: BMC Gastroenterology 2020 20:301

    Content type: Research article

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  13. Cryptogenic multifocal ulcer stenosing enteritis (CMUSE) is a rare disease characterized by multiple superficial ulcers, stenosis, and obstruction of the small intestine of unknown origin, and the course can r...

    Authors: Cheng Chang, Chen Jiang, Yaoyao Miao, Bin Fang and Lili Zhang

    Citation: BMC Gastroenterology 2020 20:300

    Content type: Case report

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  14. Edwardsiella tarda is a motile, facultatively anaerobic gram-negative bacillus that is isolated from a wide spectrum of animals in aquatic environments but rarely causes infection in humans. Here, we describe the...

    Authors: Koshi Ota, Hiroki Yamanoue, Nobuyuki Aizawa, Naoyuki Suzuki, Kanna Ota and Akira Takasu

    Citation: BMC Gastroenterology 2020 20:299

    Content type: Case report

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  15. Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell malignancy caused by human T-cell leukemia virus type 1. The clinical course of ATLL is very heterogeneous, and many organs, including the gastroint...

    Authors: Tadashi Miike, Hiroshi Kawakami, Takuro Kameda, Shojiro Yamamoto, Yoshihiro Tahara, Tomonori Hidaka, Yoko Kubuki, Kenji Yorita, Yutaka Akiyama, Yasuji Arimura, Yoshimasa Kubota, Hiroaki Kataoka and Kazuya Shimoda

    Citation: BMC Gastroenterology 2020 20:298

    Content type: Research article

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  16. Gastroesophageal reflux disease (GERD), which leads to acid reflux into the esophagus, is a common gastrointestinal disorder. Several studies have shown the prevalence of GERD in Iranian population, but their ...

    Authors: Mohammad Karimian, Hassan Nourmohammadi, Majid Salamati, Mohammad Reza Hafezi Ahmadi, Fatemeh Kazemi and Milad Azami

    Citation: BMC Gastroenterology 2020 20:297

    Content type: Research article

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  17. Thioguanine (TG) is a thiopurine which has been used for patients with inflammatory bowel disease (IBD), who have failed azathioprine (AZA) or mercaptopurine (MP) due to adverse events or suboptimal response. ...

    Authors: Ahmed B. Bayoumy, Elsa L. S. A. van Liere, Melek Simsek, Ben Warner, Aathavan Loganayagam, Jeremy D. Sanderson, Simon Anderson, Jonathan Nolan, Nanne K. de Boer, Chris J. J. Mulder and Azhar Ansari

    Citation: BMC Gastroenterology 2020 20:296

    Content type: Research article

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  18. Amebiasis is a rare condition in developed countries but epidemiologically growing. Clinical manifestation may range from asymptomatic to invasive disease, amoebic liver abscess being the most common manifesta...

    Authors: Matteo Borro, Giuseppe Murdaca, Monica Greco, Simone Negrini and Maurizio Setti

    Citation: BMC Gastroenterology 2020 20:295

    Content type: Case report

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  19. Cytomegalovirus (CMV) infection can significantly complicate and worsen the condition of acute severe ulcerative colitis (UC) patients. We aimed to explore the predictive risk factors to prevent and identify C...

    Authors: Hong Yang, Kaichun Wu, Hongjie Zhang, Qin Owyang, Yinglei Miao, Fang Gu, Naizhong Hu, Kaifang Zou, Jianqiu Sheng, Jin Li, Ping Zheng, Yulan Liu, Junxia Li, Xiaodi Wang, Yongdong Wu, Yaozong Yuan…

    Citation: BMC Gastroenterology 2020 20:294

    Content type: Research article

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  20. It is unclear if the 99mTc-sodium phytate (99mTc-SP) is as reliable as the gold-standard 99mTc-sulfur colloid (99mTc-SC) for gastric emptying scintigraphy (GES). This study is aimed to compare the emptying rates ...

    Authors: Norazlina Mat Nawi, Nashrulhaq Tagiling, Mohd Fazrin Mohd Rohani, Wan Mohd Nazlee Wan Zainon, Muhammad Saifuddin Zanial, Mung Seong Wong and Yeong Yeh Lee

    Citation: BMC Gastroenterology 2020 20:293

    Content type: Research article

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  21. With the recent increased use of lanthanum carbonate, several cases of lanthanum phosphate deposition to gastric mucosa in dialysis patients have been reported. However, the endoscopic appearance of the early-...

    Authors: Akiko Ohno, Jun Miyoshi, Hidesato Tanabe, Mitsunori Kusuhara, Masao Toki, Tomohiro Chiba, Hiroaki Shimoyamada, Junji Shibahara and Tadakazu Hisamatsu

    Citation: BMC Gastroenterology 2020 20:292

    Content type: Case report

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  22. Esophageal tuberculosis (ET) is relatively rare, and the diagnosis is challenging. The aim of this study was to evaluate the clinical features of ET and highlight the role of endoscopic ultrasonography (EUS) i...

    Authors: Rong Zhu, Yonghua Bai, Yuankun Zhou, Xingguo Fang, Kui Zhao, Biguang Tuo and Huichao Wu

    Citation: BMC Gastroenterology 2020 20:291

    Content type: Research article

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  23. Poorly differentiated anal neuroendocrine carcinomas (ANECs) are rare lesions with poor prognosis, and the molecular etiology is only partially understood.

    Authors: Carl Christofer Juhlin, Henrik Falhammar, Magnus Kjellman, Jan Åhlén, Staffan Welin and Jan Calissendorff

    Citation: BMC Gastroenterology 2020 20:290

    Content type: Case report

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  24. With the improvement of treatment and prognosis for patients with late malignant diseases, certain malignancies with distant metastasis (M1 category) have been further classified into M1a (single metastatic si...

    Authors: Fang Feng, Wei Cai, Gaoming Wang, Weigang Chen, Haochang Yang, Mingyu Sun and Li Zhou

    Citation: BMC Gastroenterology 2020 20:289

    Content type: Research article

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  25. The importance of donor-specific antibodies (DSA) after liver transplantation (LT) for graft and patient survival is an ongoing controversy. So far it has not been elucidated when and in how far DSA are harmfu...

    Authors: Katharina Willuweit, Alexandra Frey, Lisa Bieniek, Andreas Heinold, Matthias Büchter, Peter A. Horn, Heiner Wedemeyer and Kerstin Herzer

    Citation: BMC Gastroenterology 2020 20:288

    Content type: Research article

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  26. In the diagnosis of IgG4-related sclerosing cholangitis (IgG4-SC), differentiation from extrahepatic cholangiocarcinoma (ECC) is extremely important but is still a clinical challenge. This study aimed to eluci...

    Authors: Yasutaka Ishii, Masahiro Serikawa, Tomofumi Tsuboi, Ryota Kawamura, Ken Tsushima, Shinya Nakamura, Tetsuro Hirano, Ayami Fukiage, Juri Ikemoto, Yusuke Kiyoshita, Sho Saeki, Yosuke Tamura and Kazuaki Chayama

    Citation: BMC Gastroenterology 2020 20:287

    Content type: Research article

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  27. Pancreatic panniculitis is a rare skin manifestation in pancreatic disease patients that most frequently develops on the lower legs. We report the unique case of a 68-year-old man who suffered from pancreatic ...

    Authors: Yuki Yamashita, Satoru Joshita, Tetsuya Ito, Masafumi Maruyama, Shuichi Wada and Takeji Umemura

    Citation: BMC Gastroenterology 2020 20:286

    Content type: Case report

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  28. Recent improvements in stone extraction implements and apparatus have lessened the complexity of the endoscopic bile duct stone treatment. However, despite confirmation of complete removal, cases of residual s...

    Authors: Akashi Fujita, Kazunari Nakahara, Yosuke Michikawa, Ryo Morita, Keigo Suetani, Junya Sato, Yosuke Igarashi, Ryuichiro Araki, Hiroki Ikeda, Kotaro Matsunaga, Tsunamasa Watanabe and Fumio Itoh

    Citation: BMC Gastroenterology 2020 20:285

    Content type: Research article

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  29. The prevalence of chronic constipation is increased in females and with age or environmental (low temperature), racial, socioeconomic, and habitual risk factors. The impact of low outside temperature on consti...

    Authors: Hiroshi Mihara, Aiko Murayama, Sohachi Nanjo, Takayuki Ando, Kazuto Tajiri, Haruka Fujinami, Masaaki Yamada and Ichiro Yasuda

    Citation: BMC Gastroenterology 2020 20:284

    Content type: Research article

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  30. Pressure sores are sometimes refractory to treatment, often due to malnutrition. Small intestinal bacterial overgrowth (SIBO) obstructs absorption in the digestive tract and causes malnutrition. However, littl...

    Authors: Yoshitaka Kubota, Hidekazu Nagano, Kentaro Ishii, Takashi Kono, Satomi Kono, Shinsuke Akita, Nobuyuki Mitsukawa and Tomoaki Tanaka

    Citation: BMC Gastroenterology 2020 20:283

    Content type: Case report

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  31. Inflammatory pseudotumour has been used to describe an inflammatory or fibrosing tumoral process of an undetermined cause that may involve a variety of organ systems, including the lungs, spleen, liver, lymph ...

    Authors: Antonio Calvo, Jesús Salas, Gloria Muñoz, Ana Díez and María Coral de la Vega

    Citation: BMC Gastroenterology 2020 20:282

    Content type: Case report

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  32. The incidence of mucinous appendiceal adenocarcinomas (MAA) has increased over the past three decades. Advanced stage tumor diagnosis is likely attributable to non-specific findings. Here we describe advanced ...

    Authors: Katerina Roma, Mark Baldwin, Daniel Sedmak, Matthew Silva, William Stellar and Gina Many

    Citation: BMC Gastroenterology 2020 20:281

    Content type: Case report

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  33. While Helicobacter pylori (H. pylori) ulcers has declined recently, H. pylori-negative and/or gastrotoxic drug-negative peptic ulcers (HNGN-PU) has increased. This study aimed to analyze the etiology of peptic ul...

    Authors: Jung Yeon Joo, Jin Min Cho, In Hyuk Yoo and Hye Ran Yang

    Citation: BMC Gastroenterology 2020 20:280

    Content type: Research article

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  34. We aimed to compare the safety and effectiveness of the following procedures after pancreaticoduodenectomy: isolated pancreaticojejunostomy, isolated gastrojejunostomy, and conventional pancreaticojejunostomy.

    Authors: Yunxiao Lyu, Bin Wang, Yunxiao Cheng, Yueming Xu and Wei Bing Du

    Citation: BMC Gastroenterology 2020 20:279

    Content type: Research article

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  35. Almost all liver tumours can be removed laparoscopically, but some difficult tumour locations complicate laparoscopic surgery. Recurrent liver tumours often pose great difficulties to laparoscopic surgery due ...

    Authors: Baifeng Li, Tao Liu, Yijie Zhang and Jialin Zhang

    Citation: BMC Gastroenterology 2020 20:278

    Content type: Case report

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  36. Although the etiology of pouchitis remains unknown, inflammatory cytokines are significantly associated with the pathogenesis of pouchitis. The cytokine responses that characterize inflammatory bowel diseases ...

    Authors: Takahito Kitajima, Yoshiki Okita, Mikio Kawamura, Satoru Kondo, Yuji Toiyama, Keiichi Uchida and Masato Kusunoki

    Citation: BMC Gastroenterology 2020 20:277

    Content type: Research article

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  37. Left-sided portal hypertension (LSPH) is an extremely rare clinical syndrome, and it is the only form of curable portal hypertension. It is primarily caused by pancreatic disease, and is associated with compli...

    Authors: Dajun Yu, Xiaolan Li, Jianping Gong, Jinzheng Li, Fei Xie and Jiejun Hu

    Citation: BMC Gastroenterology 2020 20:276

    Content type: Case report

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  38. The extraesophageal manifestations of gastroesophageal reflux disease (GERD) are more difficult to manage than the typical symptoms. The efficacy of high-dose and standard-dose proton pump inhibitors against t...

    Authors: Jae Ho Cho, Cheol Min Shin, Hyuk Yoon, Young Soo Park, Nayoung Kim and Dong Ho Lee

    Citation: BMC Gastroenterology 2020 20:275

    Content type: Research article

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  39. African Americans (AA) are at high risk for Colorectal Cancer (CRC). Studies report a 30–60% increase in CRC risk with physical inactivity, obesity and metabolic syndrome. Activation of the WNT/β-catenin (CTNN...

    Authors: Babak Shokrani, Hassan Brim, Tahmineh Hydari, Ali Afsari, Edward Lee, Mehdi Nouraie, Zaki Sherif and Hassan Ashktorab

    Citation: BMC Gastroenterology 2020 20:274

    Content type: Research article

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  40. Epstein-Barr virus-associated early gastric carcinoma with lymphoid stroma (EBV-GCLS) is a rare variant of early gastric carcinomas. Clinicopathological features of this variant remain obscure, especially in C...

    Authors: Yuqing Cheng, Xiaoli Zhou, Kequn Xu, Jin Huang and Qin Huang

    Citation: BMC Gastroenterology 2020 20:273

    Content type: Research article

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  41. Segmental absence of intestinal musculature (SAIM) is a rare cause of intestinal obstruction and perforation due to partial or complete defects in the intestinal muscularis propria in neonates and is occasiona...

    Authors: Kosuke Kashiwagi, Keisuke Jimbo, Kenji Hosoi, Go Miyano, Takahiro Kudo, Atsuyuki Yamataka and Toshiaki Shimizu

    Citation: BMC Gastroenterology 2020 20:272

    Content type: Case report

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  42. Patients with liver cirrhosis typically exhibit abnormal coagulation parameters in conventional coagulation tests (CCTs). Rotational thromboelastometry (ROTEM) is a holistic blood coagulation assay. This metho...

    Authors: Jessica Seeßle, Jan Löhr, Marietta Kirchner, Josefin Michaelis and Uta Merle

    Citation: BMC Gastroenterology 2020 20:271

    Content type: Research article

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  43. Reflux esophagitis (RE) and absence of Helicobacter pylori (non-H. pylori) are considered to be associated with the progression to long-segment Barrett’s esophagus (LSBE). However, it is difficult to assess this ...

    Authors: Genki Usui, Tomohiro Shinozaki, Toyohisa Jinno, Kazutoshi Fujibayashi, Teppei Morikawa, Toshiaki Gunji and Nobuyuki Matsuhashi

    Citation: BMC Gastroenterology 2020 20:270

    Content type: Research article

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  45. Adenomatous gallbladder polyps, premalignant lesions of the gallbladder, have fatal outcomes, whereas cholesterol polyps have benign features. Herein, we proposed a novel, predictive scoring model of adenomato...

    Authors: Eun-young Kim and Tae-ho Hong

    Citation: BMC Gastroenterology 2020 20:268

    Content type: Research article

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  46. A pyogenic liver abscess (PLA) represents a pus-filled cavity within the liver parenchyma caused by the invasion and multiplication of bacteria. The most common offender isolated from the PLA in children is Staph...

    Authors: Petar Rasic, Srdjan Bosnic, Zorica V. Vasiljevic, Slavisa M. Djuricic, Vesna Topic, Maja Milickovic and Djordje Savic

    Citation: BMC Gastroenterology 2020 20:267

    Content type: Case report

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  47. Helicobacter pylori is accounted as the most etiologic agent for digestive disorders, in particular, the most important of them i.e. peptic ulcer and gastric cancer. In the recent years, association of vacA genot...

    Authors: Masoud Keikha, Mohammad Ali-Hassanzadeh and Mohsen Karbalaei

    Citation: BMC Gastroenterology 2020 20:266

    Content type: Research article

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  48. MELD score and MELD score derivates are used to objectify and grade the risk of liver-related death in patients with liver cirrhosis. We recently proposed a new predictive model that combines serum creatinine ...

    Authors: Tomasz Dziodzio, Robert Öllinger, Wenzel Schöning, Antonia Rothkäppel, Radoslav Nikolov, Andrzej Juraszek, Paul V. Ritschl, Martin Stockmann, Johann Pratschke and Maximilian Jara

    Citation: BMC Gastroenterology 2020 20:265

    Content type: Research article

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  49. Postoperative pancreatic fistula (POPF) is a life-threatening postoperative complication. The aim of this study was to evaluate the efficacy of the fistula risk score (FRS) and preoperative body composition fa...

    Authors: Tomoyuki Abe, Hironobu Amano, Tsuyoshi Kobayashi, Keiji Hanada, Minoru Hattori, Masahiro Nakahara, Hideki Ohdan and Toshio Noriyuki

    Citation: BMC Gastroenterology 2020 20:264

    Content type: Research article

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  50. Delayed bowel obstruction due to seat belt injury is extremely rare. The delayed onset of nonspecific symptoms makes a timely diagnosis difficult. A deep understanding of the characteristics of this condition ...

    Authors: Xing-Bin Ma, Bao-Guang Hu, Wei Wang, Xian-Yong Cheng, Chun-Di Guan and Cheng-Xia Liu

    Citation: BMC Gastroenterology 2020 20:262

    Content type: Case report

    Published on:

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