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  1. The question of whether the choice of preservation solution affects outcome after liver transplantation is still not satisfactorily answered. The purpose of this study is to examine the preservation solutions’...

    Authors: Alexander Kaltenborn, Jill Gwiasda, Volker Amelung, Christian Krauth, Frank Lehner, Felix Braun, Jürgen Klempnauer, Benedikt Reichert and Harald Schrem
    Citation: BMC Gastroenterology 2014 14:169
    Content type: Research article Published on:

  2. Semi-solidification by gelation or increased viscosity could slow the influx of liquid enteral nutrition (EN) into the small intestine. A liquid EN formula containing pectin that gels under acidic conditions s...

    Authors: Ippei Yamaoka, Takeshi Kikuchi, Naoyuki Endo and Goro Ebisu
    Citation: BMC Gastroenterology 2014 14:168
    Content type: Research article Published on:

  3. Foreign body ingestion complicated by perforation of the digestive tract is a well-known occurrence. Contrary to this, perforation by fishbones has most often been described in South East Asian populations, an...

    Authors: Pierre-François Laterre and Carole Dangoisse
    Citation: BMC Gastroenterology 2014 14:167
    Content type: Case report Published on:

    The Erratum to this article has been published in BMC Gastroenterology 2015 15:27

  4. Few studies have compared the prognosis and liver-related mortality in patients with NAFLD (nonalcoholic fatty liver disease) and AFLD (alcoholic fatty liver disease). We aimed to investigate the etiology and ...

    Authors: Svanhildur Haflidadottir, Jon G Jonasson, Helga Norland, Sylvia O Einarsdottir, David E Kleiner, Sigrun H Lund and Einar S Björnsson
    Citation: BMC Gastroenterology 2014 14:166
    Content type: Research article Published on:

  5. Diagnosis of choledocholithiasis requires clinical manifestations and imaging examination findings suggesting a stone in the common bile duct (CBD), but these factors are not highly sensitive or specific. The ...

    Authors: Varayu Prachayakul, Pitulak Aswakul, Patommatat Bhunthumkomol and Morakod Deesomsak
    Citation: BMC Gastroenterology 2014 14:165
    Content type: Research article Published on:

  6. Laparoscopic cholecystectomy (LC) has become the “gold standard” for treating symptomatic gallstones. Innovative methods, such as a scarless therapeutic procedure through a natural orifice are being introduced...

    Authors: Nan Ge, Zhiguo Wang, Siyu Sun, Sheng Wang, Guoxin Wang, Shiwei Sun, Linlin Feng, Fei Yang, Wenzhuang Ma, Shupeng Wang, Xiang Liu, Jintao Guo and Wen Liu
    Citation: BMC Gastroenterology 2014 14:164
    Content type: Research article Published on:

  7. Aberrant R/subclavian artery is a rare congenital anomaly involving aortic arch. Oesophageal carcinoma with associated aberrant R/subclavian artery is very rare and only few cases has been reported in literatu...

    Authors: Duminda Subasinghe, Hemantha Sudasinghe, Chathuranga Tisara Keppetiyagama, Sumana D Handagala, Anuja Abayadeera and Merrenna IM De Zoysa
    Citation: BMC Gastroenterology 2014 14:163
    Content type: Case report Published on:

  8. In up to 30 percent of small bowel capsule endoscopy procedures, the capsule does not reach the cecum within recording time. A prolonged gastric transit time has been recognized as a risk factor for incomplete...

    Authors: Jessie Westerhof, Rinse K Weersma, Reinier A Hoedemaker and Jan J Koornstra
    Citation: BMC Gastroenterology 2014 14:162
    Content type: Research article Published on:

  9. The influence of size on the effectiveness of nasobiliary catheters has not yet been studied. We compared biliary drainage effectiveness and procedure-related discomfort and adverse events in 5 French (Fr) and...

    Authors: Toshio Fujisawa, Koichi Kagawa, Shunsuke Watanabe, Kantaro Hisatomi, Kensuke Kubota, Hajime Sato, Atsushi Nakajima and Nobuyuki Matsuhashi
    Citation: BMC Gastroenterology 2014 14:161
    Content type: Research article Published on:

  10. Intrahepatic cholestasis of pregnancy (ICP) is a cholestasis condition caused by elevated levels of serum bile acids that mainly occurs in the third trimester of pregnancy. Maternal symptoms include pruritus; ...

    Authors: Kenya Kamimura, Hiroyuki Abe, Naomi Kamimura, Masayuki Yamaguchi, Maiko Mamizu, Kanna Ogi, Yoshifumi Takahashi, Ken-ichi Mizuno, Hiroteru Kamimura, Yuji Kobayashi, Manabu Takeuchi, Kunihiko Yoshida, Kyoko Yamada, Takayuki Enomoto, Koichi Takakuwa, Minoru Nomoto…
    Citation: BMC Gastroenterology 2014 14:160
    Content type: Case report Published on:

  11. Systemic amyloidoses is a heterogeneous group of diseases either acquired or hereditary. Amyloidoses can involve the gastrointestinal tract and the nature of the precursor protein that forms the fibrils deposi...

    Authors: Estelle Jean, Mikael Ebbo, Sophie Valleix, Lucas Benarous, Laurent Heyries, Aurélie Grados, Emmanuelle Bernit, Gilles Grateau, Thomas Papo, Brigitte Granel, Laurent, Daniel, Jean-Robert Harlé and Nicolas Schleinitz
    Citation: BMC Gastroenterology 2014 14:159
    Content type: Case report Published on:

  12. Laparoscopy-assisted low anterior resection (LAR) of colorectal cancer, using a posterior surgical approach, is a difficult and controversial procedure to perform. We report successful operations on 13 patient...

    Authors: Hao Qu, Yan-Fu Du, Min-Zhe Li, Yu-Dong Zhang and Jian Shen
    Citation: BMC Gastroenterology 2014 14:158
    Content type: Research article Published on:

  13. Recent studies have focused on the diagnostic and prognostic significance of CD24 and CD44 expression in human cancers. This study aimed to explore changes in CD44 and CD24 expression levels in patients with g...

    Authors: Xueyuan Cao, Donghui Cao, MeiShan Jin, Zhifang Jia, Fei Kong, Hongxi Ma, Yinping Wang and Jing Jiang
    Citation: BMC Gastroenterology 2014 14:157
    Content type: Research article Published on:

  14. Predicting response to proton pump inhibitor (PPI) treatment can aid the effective management of gastroesophageal reflux disease (GERD). The aim was to investigate the predictors of symptomatic response to pan...

    Authors: Khean Lee Goh, Kee Don Choi, Myung-Gyu Choi, Tsai-Yuan Hsieh, Hwoon-Yong Jung, Han-Chung Lien, Jayaram Menon, Steven Mesenas, Hyojin Park, Bor-Shyang Sheu and Justin CY Wu
    Citation: BMC Gastroenterology 2014 14:156
    Content type: Research article Published on:

  15. Meckel’s diverticulum is a congenital anomaly of the gastrointestinal tract. About 98% of affected patients are asymptomatic. Small intestinal examination has become easier since the development of double-ball...

    Authors: Masashi Fukushima, Chiharu Kawanami, Satoko Inoue, Akihiko Okada, Yukihiro Imai and Tetsuro Inokuma
    Citation: BMC Gastroenterology 2014 14:155
    Content type: Case report Published on:

  16. Aim was to explore the association of ERCC1 and TS mRNA levels with the disease free survival (DFS) in Chinese colorectal cancer (CRC) patients receiving oxaliplatin and 5-FU based adjuvant chemotherapy.

    Authors: Sheng Li, Liangjun Zhu, Li Yao, Lei Xia and Liangxi Pan
    Citation: BMC Gastroenterology 2014 14:154
    Content type: Research article Published on:

  17. Very little is known about whether mortality following acute pancreatitis may be influenced by the following five factors: social deprivation, week day of admission, recruitment of junior doctors in August eac...

    Authors: Stephen E Roberts, Kymberley Thorne, P Adrian Evans, Ashley Akbari, David G Samuel and John G Williams
    Citation: BMC Gastroenterology 2014 14:153
    Content type: Research article Published on:

  18. Gastric endoscopic submucosal dissection (ESD) has gradually come to be recommended as the optimal treatment for early gastric cancer; however, one of the primary issues is postoperative bleeding. Although sec...

    Authors: Fumiaki Takahashi, Naoto Yoshitake, Takashi Akima, Hitoshi Kino, Masakazu Nakano, Chieko Tsuchida, Kohei Tsuchida, Keiichi Tominaga, Takako Sasai, Hironori Masuyama and Hideyuki Hiraishi
    Citation: BMC Gastroenterology 2014 14:9004
    Content type: Research article Published on:

  19. Numerous pathological processes that affect liver function in patients with liver failure have been identified. Among them, hyperammonia is one of the most common phenomena.The purpose of this study was to det...

    Authors: Jingjing Li, Zujiang Yu, Qiongye Wang, Duolu Li, Bin Jia, Yubing Zhou, Yanwei Ye, Shen Shen, Yanfang Wang, Shasha Li, Lu Bai and Quancheng Kan
    Citation: BMC Gastroenterology 2014 14:151
    Content type: Research article Published on:

  20. Abdominal pain predominant functional gastrointestinal diseases (AP-FGD) are commonly seen in the paediatric age group. It has significant impact on daily activities of affected children. Main objective of thi...

    Authors: Niranga Manjuri Devanarayana, Shaman Rajindrajith and Marc A Benninga
    Citation: BMC Gastroenterology 2014 14:150
    Content type: Research article Published on:

  21. The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with ch...

    Authors: Zhengwei Wen, Xiaomei Li, Qian Lu, Julie Brunson, Miao Zhao, Jianfeng Tan, Chonghua Wan and Pingguang Lei
    Citation: BMC Gastroenterology 2014 14:149
    Content type: Research article Published on:

  22. Acetaminophen (APAP) is one of the most widely used analgesic and antipyretic pharmaceutical substances in the world and accounts for most cases of drug induced liver injury resulting in acute liver failure. A...

    Authors: Niels Steinebrunner, Carolin Mogler, Spiros Vittas, Birgit Hoyler, Catharina Sandig, Wolfgang Stremmel and Christoph Eisenbach
    Citation: BMC Gastroenterology 2014 14:148
    Content type: Research article Published on:

  24. Evaluation of pregnant women with known or suspected Crohn’s disease (CD) remains a challenge. Magnetic Resonance Enterography (MRE) is a promising diagnostic tool in these patients; however, the clinical data...

    Authors: Myriam D Stern, Uri Kopylov, Shomron Ben-Horin, Sarah Apter and Marianne Michal Amitai
    Citation: BMC Gastroenterology 2014 14:146
    Content type: Research article Published on:

  25. Hepatitis B virus (HBV) infection is a serious public health problem worldwide. This study aimed to investigate the relationship between serum alpha-fetoprotein (AFP) levels and pathological stages of liver bi...

    Authors: Yu-rui Liu, Bin-bin Lin, Da-wu Zeng, Yue-yong Zhu, Jing Chen, Qi Zheng, Jing Dong and Jia-ji Jiang
    Citation: BMC Gastroenterology 2014 14:145
    Content type: Research article Published on:

  26. Gastroesophageal reflux disease (GERD) is the most common gastrointestinal disease, and the cost of health care and lost productivity due to GERD is extremely high. Recently described side effects of long-term...

    Authors: Ai Kubo, Gladys Block, Charles P Quesenberry Jr, Patricia Buffler and Douglas A Corley
    Citation: BMC Gastroenterology 2014 14:144
    Content type: Research article Published on:

  27. Gemcitabine/Cisplatin (Gem/CDDP) combination has demonstrated a clear survival advantage over gemcitabine alone and has become a new standard in advanced Biliary Tract Carcinoma (aBTC). However, Gemcitabine/Ox...

    Authors: Frédéric Fiteni, Marine Jary, Franck Monnien, Thierry Nguyen, Eric Beohou, Martin Demarchi, Erion Dobi, Francine Fein, Denis Cleau, Serge Fratté, Virginie Nerich, Franck Bonnetain, Xavier Pivot, Christophe Borg and Stefano Kim
    Citation: BMC Gastroenterology 2014 14:143
    Content type: Research article Published on:

  28. Crohn’s disease (CD) is a lifelong, relapsing and remitting inflammatory condition of the intestine. Medical imaging is crucial for diagnosis, phenotyping, activity assessment and detecting complications. Dive...

    Authors: Stuart Taylor, Susan Mallett, Gauraang Bhatnagar, Stuart Bloom, Arun Gupta, Steve Halligan, John Hamlin, Ailsa Hart, Antony Higginson, Ilan Jacobs, Sara McCartney, Steve Morris, Nicola Muirhead, Charles Murray, Shonit Punwani, Manuel Rodriguez-Justo…
    Citation: BMC Gastroenterology 2014 14:142
    Content type: Study protocol Published on:

  29. Recent technological advances have stimulated the development of endoscopic optical biopsy technologies. This study compared the accuracy of endoscopic diagnosis using magnifying narrow-band imaging (NBI) and ...

    Authors: Kengo Nagai, Ryu Ishihara, Shingo Ishiguro, Takashi Ohta, Hiromitsu Kanzaki, Takeshi Yamashina, Kenji Aoi, Noriko Matsuura, Takashi Ito, Mototsugu Fujii, Sachiko Yamamoto, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Noriya Uedo, Hiroyasu Iishi…
    Citation: BMC Gastroenterology 2014 14:141
    Content type: Research article Published on:

  31. Coeliac disease is a common enteropathy characterized by an increased mortality mainly due to its complications. The natural history of complicated coeliac disease is characterised by two different types of co...

    Authors: Federico Biagi, Alessandra Marchese, Francesca Ferretti, Rachele Ciccocioppo, Annalisa Schiepatti, Umberto Volta, Giacomo Caio, Carolina Ciacci, Fabiana Zingone, Anna D’Odorico, Antonio Carroccio, Giuseppe Ambrosiano, Pasquale Mansueto, Antonio Gasbarrini, Anna Chiara Piscaglia, Alida Andrealli…
    Citation: BMC Gastroenterology 2014 14:139
    Content type: Research article Published on:

  32. Alkaline sphingomyelinase (NPP7) is an ecto-enzyme expressed in intestinal mucosa, which hydrolyses sphingomyelin (SM) to ceramide and inactivates platelet activating factor. It is also expressed in human live...

    Authors: Rui-Dong Duan, Ulf Hindorf, Yajun Cheng, Per Bergenzaun, Mats Hall, Erik Hertervig and Åke Nilsson
    Citation: BMC Gastroenterology 2014 14:138
    Content type: Research article Published on:

  33. The societal, clinical and economic burden imposed by the complications of chronic hepatitis C virus (HCV) infection - including cirrhosis and hepatocellular carcinoma (HCC) - is expected to increase over the ...

    Authors: Matthew E Cramp, William M Rosenberg, Steven D Ryder, Sarah Blach and Julie Parkes
    Citation: BMC Gastroenterology 2014 14:137
    Content type: Research article Published on:

  34. WHO guidelines recommend zinc supplementation as a key adjunct therapy for childhood diarrhea in developing countries, however zinc’s anti-diarrheal effects remain only partially understood. Recently, it has b...

    Authors: Camila AA de Queiroz, Said Gonçalves C Fonseca, Priscila B Frota, Ítalo L Figueiredo, Karoline S Aragão, Carlos Emanuel C Magalhães, Cibele BM de Carvalho, Aldo Ângelo M Lima, Ronaldo A Ribeiro, Richard L Guerrant, Sean R Moore and Reinaldo B Oriá
    Citation: BMC Gastroenterology 2014 14:136
    Content type: Research article Published on:

  35. This study aimed to better understand the supporting role that mutational profiling (MP) of DNA from microdissected cytology slides and supernatant specimens may play in the diagnosis of malignancy in fine-nee...

    Authors: Nidhi Malhotra, Sara A Jackson, Lindsay L Freed, Mindi A Styn, Mary K Sidawy, Nadim G Haddad and Sydney D Finkelstein
    Citation: BMC Gastroenterology 2014 14:135
    Content type: Research article Published on:

  36. Hydroxyurea at a relatively low dose is frequently prescribed to induce hemoglobin F production in patients with sickle cell and β-thalassemia diseases because of its good efficacy and safety profiles. However...

    Authors: Kochawan Boonyawat, Sansanee Wongwaisayawan, Prawat Nitiyanant and Vichai Atichartakarn
    Citation: BMC Gastroenterology 2014 14:134
    Content type: Case report Published on:

  37. Although pyogenic liver abscess (PPLA) fatalities are decreasing owing to early diagnosis and effective treatments, PPLA-associated complications still exist. The purpose of this study was to analyze the chara...

    Authors: Chang-Hua Chen, Shung-Sheng Wu, Hung-Chi Chang and Yu-Jun Chang
    Citation: BMC Gastroenterology 2014 14:133
    Content type: Research article Published on:

  38. Hepatitis C virus (HCV) and Schistosoma mansoni are major causes of chronic liver disease (CLD) in which immune alteration is common. Recent studies suggested that certain platelets and lymphocytes activation mar...

    Authors: Mahmoud M Kamel, Shawky A Fouad and Maha MA Basyoni
    Citation: BMC Gastroenterology 2014 14:132
    Content type: Research article Published on:

  39. The aim of this study was to assess whether two-years treatment with Pirfenidone influences necroinflammation, fibrosis and steatosis, serum levels of TGF-β1, IL-6, TNF-α and CB1 and CB2 gene expression, in pa...

    Authors: Lucia Flores-Contreras, Ana S Sandoval-Rodríguez, Mayra G Mena-Enriquez, Silvia Lucano-Landeros, Inmaculada Arellano-Olivera, Arnulfo Álvarez-Álvarez, M Guadalupe Sanchez-Parada and Juan Armendáriz-Borunda
    Citation: BMC Gastroenterology 2014 14:131
    Content type: Research article Published on:

  40. Gastrointestinal bleeding (GIB) is a common and often serious complication after stroke. Although several risk factors for post-stroke GIB have been identified, no reliable or validated scoring system is curre...

    Authors: Ruijun Ji, Haipeng Shen, Yuesong Pan, Penglian Wang, Gaifen Liu, Yilong Wang, Hao Li, Aneesh B Singhal and Yongjun Wang
    Citation: BMC Gastroenterology 2014 14:130
    Content type: Research article Published on:

  42. Obesity is associated with a risk of gastroesophageal reflux disease. The pharmacodynamic efficacy of proton pump inhibitors has not been specifically evaluated in obese subjects. The aim of this study was to ...

    Authors: Kafia Belhocine, Fabienne Vavasseur, Christelle Volteau, Laurent Flet, Yann Touchefeu and Stanislas Bruley des Varannes
    Citation: BMC Gastroenterology 2014 14:128
    Content type: Research article Published on:

  44. Staphylococcus epidermidis is the most frequently isolated species of the coagulase negative staphylococci from human stool. However, it is not clear how its presence in the gut affects the cellular structures a...

    Authors: Ezekiel Olugbenga Akinkunmi, Oluwole Isaac Adeyemi, Oluwatoyin Abimbola Igbeneghu, Esther Omowunmi Olaniyan, Abidemi Emmanuel Omonisi and Adebayo Lamikanra
    Citation: BMC Gastroenterology 2014 14:126
    Content type: Research article Published on:

  45. When primary care of constipation fails, the patient may need emergency hospitalisation for disimpaction. This study aimed to provide population-based data on the number of unplanned admissions and the cost to...

    Authors: Humaira Ansari, Zahid Ansari, John M Hutson and Bridget R Southwell
    Citation: BMC Gastroenterology 2014 14:125
    Content type: Research article Published on:

  46. Early induction with biologics can reduce complications in patients with Crohn’s disease (CD) and improve their quality of life. The safety of biologics, however, is uncertain. Granulocyte and monocyte adsorpt...

    Authors: Takumi Fukuchi, Hiroshi Nakase, Satoshi Ubukata, Minoru Matsuura, Takuya Yoshino, Takahiko Toyonaga, Keiji Shimazu, Hideaki Koga, Hiroshi Yamashita, Dai Ito and Kiyoshi Ashida
    Citation: BMC Gastroenterology 2014 14:124
    Content type: Research article Published on:

  47. Hirschsprung’s disease (HSCR) is the most common congenital gut motility disorder. We aimed to investigate the roles of miR-195 in the pathogenesis of HSCR.

    Authors: Hao Lei, Junwei Tang, Hongxing Li, Hongwei Zhang, Changgui Lu, Huan Chen, Wei Li, Yankai Xia and Weibing Tang
    Citation: BMC Gastroenterology 2014 14:123
    Content type: Research article Published on:

  48. Colonic lipomas (CL) are rare benign adipose tumours usually found incidentally during colonoscopy. Endoscopic resection of symptomatic large CL remains controversial, since significant rates of perforation ha...

    Authors: Hrvoje Ivekovic, Nadan Rustemovic, Tomislav Brkic, Rajko Ostojic and Klaus Monkemuller
    Citation: BMC Gastroenterology 2014 14:122
    Content type: Research article Published on:

  49. To perform a meta-analysis evaluating the diagnostic ability of fecal lactoferrin (FL) to distinguish inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS).

    Authors: Xing-lu Zhou, Wen Xu, Xiao-xiao Tang, Lai-sheng Luo, Jiang-feng Tu, Chen-jing Zhang, Xiang Xu, Qin-dong Wu and Wen-sheng Pan
    Citation: BMC Gastroenterology 2014 14:121
    Content type: Research article Published on:

  50. Statins can modify bile cholesterol and, thus, the formation of gallstones. We examined whether statin use also modifies the severity of symptomatic gallstone disease and its treatment.

    Authors: Jukka Pulkkinen, Matti Eskelinen, Vesa Kiviniemi, Tuukka Kotilainen, Markus Pöyhönen, Lasse Kilpeläinen, Pirjo Käkelä, Helena Kastarinen and Hannu Paajanen
    Citation: BMC Gastroenterology 2014 14:119
    Content type: Research article Published on:
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