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  1. Insulin is highly recommended for diabetes management in persons with liver cirrhosis. However, few studies have evaluated its long-term effects in these persons. We conducted this study to compare the risks o...

    Authors: Fu-Shun Yen, Jung-Nien Lai, James Cheng-Chung Wei, Lu-Ting Chiu, Chih-Cheng Hsu, Ming-Chih Hou and Chii-Min Hwu
    Citation: BMC Gastroenterology 2021 21:263
  2. Hepatocellular carcinoma (HCC) can lead to liver failure which renders to liver transplant. miRNAs might be detected as biomarkers in subclinical stage of several hepatobiliary disorders like HCC. Therefore, i...

    Authors: Afsoon Afshari, Ramin Yaghobi, Mohammad Hossein Karimi and Javad Mowla
    Citation: BMC Gastroenterology 2021 21:262
  3. Natural killer (NK) cells have been known to contribute to surveillance and control of hepatocellular carcinoma (HCC). However, the association of NK cell activity with stage and recurrence risk of HCC have no...

    Authors: Han Ah Lee, Hyun Gil Goh, Young-Sun Lee, Young Kul Jung, Ji Hoon Kim, Hyung Joon Yim, Min-Goo Lee, Hyunggin An, Yoon Tae Jeen, Jong Eun Yeon, Kwan Soo Byun and Yeon Seok Seo
    Citation: BMC Gastroenterology 2021 21:258
  4. The efficacy of endoscopic ultrasound (EUS) for determining the T category of gastric cancer is variable. The aim of this study was to evaluate the superiority of EUS by using the 6th edition American Joint Co...

    Authors: Chaoqun Han, Tao Xu, Qin Zhang, Jun Liu, Zhen Ding and Xiaohua Hou
    Citation: BMC Gastroenterology 2021 21:255
  5. Epstein–Barr virus (EBV)-associated NK/T-cell lymphoproliferative disorder (LPD) involving the gastrointestinal tract is rarely observed in individuals with normal immunity. The atypical clinical, colonoscopic...

    Authors: Si-Zhu Wang, Ying-Huan Dai, Jie Zhang, Fang-Gen Lu, La-Mei Yan and Shan Wu
    Citation: BMC Gastroenterology 2021 21:254
  6. Hemostasis profile is often complicated in liver cirrhosis. Thromboelastography is a global viscoelastic test recommended by the current practice guideline and consensus. This cross-sectional study aimed to ev...

    Authors: Yanglan He, Shanshan Yuan, Xiaozhong Guo, Fangfang Yi, Xiangbo Xu, Yang An, Shixue Xu, Walter Ageno and Xingshun Qi
    Citation: BMC Gastroenterology 2021 21:253
  7. The aim of this study was to analyze prognostic indicators of in-hospital mortality among patients listed for urgent liver transplantation (LT) for non-acetaminophen (APAP)-induced acute liver failure (ALF).

    Authors: Estela Regina Ramos Figueira, Joel Avancini Rocha-Filho, Cinthia Lanchotte, Lucas Souto Nacif, Luciana Bertocco de Paiva Haddad, Adriana Rochetto Assalin, Yumi Ricucci Shinkado, Agustin Moscoso Vintimilla, Flavio Henrique Ferreira Galvao and Luiz Augusto Carneiro D’Albuquerque
    Citation: BMC Gastroenterology 2021 21:252
  8. The Micro Hand S robot is a new surgical tool that has been applied to total mesorectal excision (TME) surgery for rectal cancer in our center. In this study, we compared the operative outcomes, functional out...

    Authors: Yanlei Wang, Guohui Wang, Zheng Li, Hao Ling, Bo Yi and Shaihong Zhu
    Citation: BMC Gastroenterology 2021 21:251
  9. Few studies have reported whether a biopsy in emergency gastroscopy (EG) increased the risk of rebleeding in patients with Forrest I acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) combined with su...

    Authors: Quchuan Zhao and Tianyu Chi
    Citation: BMC Gastroenterology 2021 21:250
  10. The right posterior segment (RPS) graft was introduced to overcome graft size discrepancy in living donor liver transplantation (LDLT). However, it was very rarely used in pediatric patients. Here we presented...

    Authors: Xiaoye Qu, Ping Wan, Mingxuan Feng, Bijun Qiu, Yi Luo, Tao Zhou, Jianjun Zhu, Dong Zhao, Guangxiang Gu, Jianjun Zhang and Qiang Xia
    Citation: BMC Gastroenterology 2021 21:249
  11. Undifferentiated carcinoma with osteoclast-like giant cells (UCOGCs) is a rare and aggressive non endocrine pancreatic carcinoma characterized by the presence of osteoclastic giant cells mixed with mononuclear...

    Authors: Elisabetta Cavalcanti, Nicolo’ Schena, Grazia Serino, Giulio Lantone and Raffaele Armentano
    Citation: BMC Gastroenterology 2021 21:247
  12. Several trend analyses on liver transplantation (LT) indications have been published in the U.S. and in other countries, but there are limited data on LT indication trends in Saudi Arabia (SA), especially sinc...

    Authors: Saleh A. Alqahtani, Dieter C. Broering, Saad A. Alghamdi, Khalid I. Bzeizi, Noara Alhusseini, Saleh I. Alabbad, Ali Albenmousa, Nasreen Alfaris, Faisal Abaalkhail and Waleed K. Al-hamoudi
    Citation: BMC Gastroenterology 2021 21:245
  13. Zanubrutinib is a Bruton’s tyrosine kinase inhibitor that has been recently licensed in refractory mantle cell lymphoma and under assessment in phase 3 clinical trials for other B cell malignancies. To date, t...

    Authors: Edmond Atallah, Pramudi Wijayasiri, Nicole Cianci, Khorrum Abdullah, Abhik Mukherjee and Guruprasad P. Aithal
    Citation: BMC Gastroenterology 2021 21:244
  14. Symptoms associated with acute pancreatitis can be debilitating, and treatment remains a challenge. This study aimed to investigate the efficacy of selectively inhibiting the soluble form of TNF (solTNF) using...

    Authors: Rajasa Randhi, Melissa Damon and Kirsty J. Dixon
    Citation: BMC Gastroenterology 2021 21:243
  15. Three-dimensional (3D) technology has been used in many fields, including flexible endoscopy. We evaluated the usefulness of 3D visualization for endoscopically diagnosing superficial gastric neoplasia.

    Authors: Kazutoshi Higuchi, Mitsuru Kaise, Hiroto Noda, Kumiko Kirita, Eriko Koizumi, Takamitsu Umeda, Teppei Akimoto, Jun Omori, Naohiko Akimoto, Osamu Goto, Atsushi Tatsuguchi and Katsuhiko Iwakiri
    Citation: BMC Gastroenterology 2021 21:242
  16. A chronic expanding hematoma (CEH) enlarges as a result of slight bleeding over several months, and the tissue shows a mixture of blood breakdown products, granulation tissue with capillary ingrowth, and infla...

    Authors: Yasuyuki Ono, Shuji Kariya, Miyuki Nakatani, Yutaka Ueno, Takuji Maruyama, Atsushi Komemushi, Masaki Kaibori, Masatoshi Ikeda and Noboru Tanigawa
    Citation: BMC Gastroenterology 2021 21:241
  17. The waist-to-height ratio (WHtR) has been recognised as a powerful indicator to evaluate non-alcoholic fatty liver disease (NAFLD) in recent years, but few related studies are available. Thus, clarifying the a...

    Authors: Guotai Sheng, Qiyang Xie, Rongsheng Wang, Chong Hu, Mingchun Zhong and Yang Zou
    Citation: BMC Gastroenterology 2021 21:239
  18. Neuroendocrine tumors (NETs), as a rare and heterogeneous category of solid tumors, feature various morphologies and behaviors. In recent years, the incidence of NETs has continued to increase. Endoscopic muco...

    Authors: Gholam Reza Sivandzadeh, Fardad Ejtehadi, Shima Shoaee, Ladan Aminlari, Ramin Niknam, Ali Reza Taghavi, Bita Geramizadeh, Ahmad Hormati, Ali Reza Safarpour and Kamran Bagheri Lankarani
    Citation: BMC Gastroenterology 2021 21:238
  19. We conducted a randomized controlled trial to investigate the effects of consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 in women healthcare workers. In a previous study ...

    Authors: Tetsu Kinoshita, Koutatsu Maruyama, Keiko Suyama, Mariko Nishijima, Kimiko Akamatsu, Akiko Jogamoto, Kikumi Katakami and Isao Saito
    Citation: BMC Gastroenterology 2021 21:237
  20. Vonoprazan is more potent and longer acting than traditional proton pump inhibitor. Although vonoprazan is expected to be superior to proton pump inhibitor, its efficacy in the treatment of gastric ulcers foll...

    Authors: Daisuke Kawai, Ryuta Takenaka, Mikako Ishiguro, Shotaro Okanoue, Tatsuhiro Gotoda, Yoshiyasu Kono, Koji Takemoto, Hirofumi Tsugeno and Shigeatsu Fujiki
    Citation: BMC Gastroenterology 2021 21:236
  21. Irritable bowel syndrome (IBS) is characterised by gastrointestinal (GI) and psychological symptoms (e.g., depression, anxiety, and somatization). Depression and anxiety, but not somatization, have already bee...

    Authors: Laura Prospero, Giuseppe Riezzo, Michele Linsalata, Antonella Orlando, Benedetta D’Attoma, Marta Di Masi, Manuela Martulli and Francesco Russo
    Citation: BMC Gastroenterology 2021 21:235
  22. The Cryoballoon focal ablation system (CbFAS) for dysplastic Barrett’s esophagus is simple, time-saving and has high therapeutic efficacy. This study aimed to evaluate the technical feasibility and tissue dama...

    Authors: Hironori Sunakawa, Yusuke Yoda, Nobuyoshi Takeshita, Hiro Hasegawa, Kenji Takashima, Tomohiro Kadota, Takeo Fujita, Tetsuo Akimoto, Satoshi Fujii and Tomonori Yano
    Citation: BMC Gastroenterology 2021 21:234
  23. As a nutritional index, preoperative serum prealbumin highly correlates with surgical complications. However, the correlation between preoperative prealbumin and postoperative complications remains unclear in ...

    Authors: Yuancheng Li, Xingchao Liu, Yan Jiang, Kun Wan, Wei Liu, Yanjiao Ou, Jie Bai, Yuemei You, Feng Hu, Zeliang Xu, Ping Bie, Chengcheng Zhang and Leida Zhang
    Citation: BMC Gastroenterology 2021 21:233
  24. High quality bowel preparation prior to colonoscopy can be difficult to achieve in the inpatient setting. Hospitalized patients are at risk for extended hospital stays and low diagnostic yield due to inadequat...

    Authors: Helmut Neumann, Melissa Latorre, Tim Zimmerman, Gabriel Lang, Jason Samarasena, Seth Gross, Bhaumik Brahmbhatt, Haleh Pazwash and Vladimir Kushnir
    Citation: BMC Gastroenterology 2021 21:232
  25. The clinical outcomes of drug-eluting beads transarterial chemoembolization (DEB-TACE) with doxorubicin-loaded CalliSpheres® beads for patients with unresectable or recurrent esophageal carcinoma have not been...

    Authors: Yonghua Bi, Xiaonan Shi, Jianzhuang Ren, Mengfei Yi, Xinwei Han and Min Song
    Citation: BMC Gastroenterology 2021 21:231
  26. The effect of time delay from diagnosis to surgery on the prognosis of elderly patients with liver cancer is not well known. We investigated the effect of surgical timing on the prognosis of elderly hepatocell...

    Authors: Yongfei He, Tianyi Liang, Shutian Mo, Zijun Chen, Shuqi Zhao, Xin Zhou, Liping Yan, Xiangkun Wang, Hao Su, Guangzhi Zhu, Chuangye Han and Tao Peng
    Citation: BMC Gastroenterology 2021 21:230
  27. Wilson’s disease (WD) is a rare autosomal recessive disease associated with defective biliary excretion of copper. The simultaneous occurrence of WD and systemic lupus erythematosus (SLE) has seldom been repor...

    Authors: Lishan Xu, Bin Liu, Zhaoyang Liu, Ning Tang, Chunhui She, Jing Wang, Bo Zang and Yifei Yang
    Citation: BMC Gastroenterology 2021 21:229
  28. Immune checkpoint inhibitors (ICPIs) have changed the way advanced malignancies are currently confronted, improving cancer patients’ outcomes but also generating distinct immune-related (ir) adverse events. IC...

    Authors: Stratigoula Sakellariou, Dionysia N. Zouki, Dimitrios C. Ziogas, Despoina Pouloudi, Helen Gogas and Ioanna Delladetsima
    Citation: BMC Gastroenterology 2021 21:227
  29. Percutaneous transhepatic gallbladder drainage (PTGBD) is recommended for acute cholecystitis patients at high risk for surgical treatment. However, there is no evidence about the best timing of surgery after ...

    Authors: Koichi Kimura, Eisuke Adachi, Sachie Omori, Ayako Toyohara, Takahiro Higashi, Kippei Ohgaki, Shuhei Ito, Shin-ichiro Maehara, Toshihiko Nakamura, Yoichi Ikeda and Yoshihiko Maehara
    Citation: BMC Gastroenterology 2021 21:226
  30. Endoscopic papillectomy of duodenal papillary tumors (PT) is indicated for adenomas or well-differentiated adenocarcinomas that do not involve the sphincter of Oddi. However, there is currently no reliable pre...

    Authors: Hiroyuki Tanaka, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Tadashi Iida, Eri Ishikawa, Kazuhiro Furukawa, Masanao Nakamura, Takashi Honda, Yoshie Shimoyama, Ryoji Miyahara, Naoto Kawabe, Teiji Kuzuya, Senju Hashimoto, Masatoshi Ishigami, Yoshiki Hirooka…
    Citation: BMC Gastroenterology 2021 21:224
  31. In this study, to clarify the evolving background of people with non-alcoholic fatty liver disease (NAFLD), we compared the current prevalence of NAFLD with that of 2 decades ago.

    Authors: Takuro Okamura, Yoshitaka Hashimoto, Masahide Hamaguchi, Akihiro Obora, Takao Kojima and Michiaki Fukui
    Citation: BMC Gastroenterology 2021 21:223
  32. Jackhammer esophagus is a rare esophageal motility disorder that can result in dysphagia, chest pain, and gastro-esophageal reflux symptoms. High-resolution manometry is the gold standard for diagnosis, while ...

    Authors: Apichet Sirinawasatien and Pallop Sakulthongthawin
    Citation: BMC Gastroenterology 2021 21:222
  33. Non-alcohol fatty liver disease (NAFLD) is the most common liver disease and an unhealthy lifestyle can lead to an increased risk of NAFLD. The present study aims to evaluate the association of meat consumptio...

    Authors: Hewei Peng, Xiaoxu Xie, Xinting Pan, Jing Zheng, Yidan Zeng, Xiaoling Cai, Zhijian Hu and Xian-E Peng
    Citation: BMC Gastroenterology 2021 21:221
  34. The benefits of surgical resection (SR) for various Barcelona Clinic Liver Cancer (BCLC) stages of hepatocellular carcinoma (HCC) remain unclear. We investigated the risk factors of overall survival (OS) and s...

    Authors: Yaw-Sen Chen, Pei-Min Hsieh, Hung-Yu Lin, Chao-Ming Hung, Gin-Ho Lo, Yao-Chun Hsu, I.-Cheng Lu, Chih-Yuan Lee, Tsung-Chin Wu, Jen-Hao Yeh, Pojen Hsiao, Yu-Chan Li, Ya-Chin Wang, Kun-Chou Hsieh and Chih-Wen Lin
    Citation: BMC Gastroenterology 2021 21:220
  35. Schistosoma mansoni related hepatic fibrosis is usually associated with hemodynamic alteration with increased mortality due to bleeding varices. The diagnosis of varices before bleeding imposes a big challenge in...

    Authors: Daniel W. Gunda, Elizabeth F. Mtui, Paulina M. Manyiri, David C. Majinge, Semvua B. Kilonzo, Humphrey D. Mazigo and Benson R. Kidenya
    Citation: BMC Gastroenterology 2021 21:219
  36. Constipation and obesity have common risk factors. However, little is known about the occurrence of constipation in individuals with severe obesity and the associated factors.

    Authors: Erika Aparecida Silveira, Annelisa Silva e Alves de Carvalho Santos, Jessivane Nascimento Ribeiro, Matias Noll, Ana Paula dos Santos Rodrigues and Cesar de Oliveira
    Citation: BMC Gastroenterology 2021 21:217
  37. This retrospective analysis was undertaken to evaluate the efficiency of SIRT with Y-90 microspheres and determined prognostic factors affecting patients with unresectable HCC.

    Authors: Nguyen Van Thai, Nguyen Tien Thinh, Thai Doan Ky, Mai Hong Bang, Dinh Truong Giang, Le Ngoc Ha, Mai Hong Son, Dao Duc Tien and Hyun Woong Lee
    Citation: BMC Gastroenterology 2021 21:216
  38. The normalization of liver biochemical parameters usually reflects the histological response to treatment for nonalcoholic fatty liver disease (NAFLD). Researchers have not clearly determined whether different...

    Authors: Qianqian Ma, Xianhua Liao, Congxiang Shao, Yansong Lin, Tingfeng Wu, Yanhong Sun, Shi-Ting Feng, Junzhao Ye and Bihui Zhong
    Citation: BMC Gastroenterology 2021 21:215
  39. Portal hypertension induced esophageal and gastric variceal bleeding is the main cause of death among patients of decompensated liver cirrhosis. Therefore, a standardized, biomarker-based test, to make an earl...

    Authors: Ying Zhu, Wen Xu, Wei Hu, Fang Wang, Yan Zhou, Jianguo Xu and Wei Gong
    Citation: BMC Gastroenterology 2021 21:214
  40. Colorectal cancer on the right side of the colon has been suggested to be harder to detect by colonoscopy. The aim of this study was to evaluate whether a second forward-view examination of the right side of t...

    Authors: Keshu Shan, Hongpeng Lu, Zhixin Zhang, Jiarong Xie, Lu Xu, Weihong Wang, Chunjiu Hu and Lei Xu
    Citation: BMC Gastroenterology 2021 21:213
  41. Metabolic associated fatty liver disease (MAFLD) is a new definition for liver disease associated with known metabolic dysfunction. Based on new diagnostic criteria, we aimed to investigate its prevalence and ...

    Authors: Yu-ling Chen, Hao Li, Shu Li, Zhou Xu, Shen Tian, Juan Wu, Xin-yu Liang, Xin Li, Zi-li Liu, Jun Xiao, Jia-ying Wei, Chen-yu Ma, Kai-nan Wu, Liang Ran and Ling-quan Kong
    Citation: BMC Gastroenterology 2021 21:212
  42. Pancreatic exocrine insufficiency (PEI) is associated with the outcome of pancreatic disease. However, there is no method for assessing PEI that can be used noninvasively and easily for outpatient. It has been...

    Authors: Kota Uetsuki, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Tadashi Iida, Kenta Yamamoto, Kazuhiro Furukawa, Masanao Nakamura, Takashi Honda, Masatoshi Ishigami, Yoshiki Hirooka and Mitsuhiro Fujishiro
    Citation: BMC Gastroenterology 2021 21:211

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