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  1. Physical inactivity and sarcopenia are two important predictors associated with increased morbidity and mortality in patients with cirrhosis. At present, the benefit of a home-based exercise training program i...

    Authors: Pavapol Sirisunhirun, Wimolrak Bandidniyamanon, Yonworanat Jrerattakon, Kobkun Muangsomboon, Pornpoj Pramyothin, Supot Nimanong, Tawesak Tanwandee, Phunchai Charatcharoenwitthaya, Siwaporn Chainuvati and Watcharasak Chotiyaputta
    Citation: BMC Gastroenterology 2022 22:66
    Content type: Research Published on:

  2. Peptic ulcer bleeding remains a typical medical emergency with significant morbidity and mortality. Peptic ulcer rebleeding often occurs within three days after emergent endoscopic hemostasis. Our study aims t...

    Authors: Yongkang Lai, Yuling Xu, Zhenhua Zhu, Xiaolin Pan, Shunhua Long, Wangdi Liao, Bimin Li, Yin Zhu, Youxiang Chen and Xu Shu
    Citation: BMC Gastroenterology 2022 22:64
    Content type: Research Published on:

  3. An increasing number of studies have shown the merits of endoscopic retrograde appendicitis therapy (ERAT) in diagnosing and treating acute uncomplicated appendicitis. However, no related prospective controlle...

    Authors: Zhemin Shen, Peilong Sun, Miao Jiang, Zili Zhen, Jingtian Liu, Mu Ye and Weida Huang
    Citation: BMC Gastroenterology 2022 22:63
    Content type: Research Published on:

  4. The pathogenesis of ulcerative colitis (UC) is closely related to the gut microbiota. Moxibustion has been used to improve the inflammation and gastrointestinal dysfunctions in gastrointestinal disorders such ...

    Authors: Qin Qi, Ya-Nan Liu, Si-Yi Lv, Huan-Gan Wu, Lin-Shuang Zhang, Zhan Cao, Hui-Rong Liu, Xiao-Mei Wang and Lu-Yi Wu
    Citation: BMC Gastroenterology 2022 22:62
    Content type: Research Published on:

  5. The purpose of this study was to investigate the diagnosis and treatment experience of traumatic duodenal ruptures in children.

    Authors: Yuanyuan Luo, Xiaobing He, Lanlan Geng, Runxian Ouyang, Yingyi Xu, Yufeng Liang, Jinhui Wu, Hong Zhang, Zhihua Ye, Rongjun Zou, Qiang Wu and Chengwei Chai
    Citation: BMC Gastroenterology 2022 22:61
    Content type: Research Published on:

  6. Stricturing gastrointestinal tuberculosis (GITB) may result in persistent symptoms even after antitubercular therapy (ATT) and may require surgical intervention. Data on efficacy and safety of endoscopic dilat...

    Authors: Pankaj Kumar, Anuraag Jena, Chhagan Lal Birda, Harjeet Singh, Pankaj Gupta, Kaushal Kishor Prasad, Usha Dutta and Vishal Sharma
    Citation: BMC Gastroenterology 2022 22:60
    Content type: Research Published on:

  7. Liver injury related to Graves’ Disease (GD) includes hepatotoxicity of thyroid hormone excess, drug-induced liver injury, and changes resulting from concomitant liver disease. Methimazole (MMI) has been shown...

    Authors: Meifang Zheng, Shiyuan Cui, Wei Zhang, David R. Brigstock and Runping Gao
    Citation: BMC Gastroenterology 2022 22:59
    Content type: Case report Published on:

  8. Peptic ulcer disease (PUD) is a common digestive disorder, of which the prevalence decreased in the past few decades. However, the decreasing tendency has plateaued in recent years due to changes in risk facto...

    Authors: Xin Xie, Kaijie Ren, Zhangjian Zhou, Chengxue Dang and Hao Zhang
    Citation: BMC Gastroenterology 2022 22:58
    Content type: Research article Published on:

  9. Rectal adenocarcinoma is one of major public health problems, severely threatening people’s health and life. Cox proportional hazard models have been applied in previous studies widely to analyze survival data...

    Authors: Xu Zhang, Fengshuo Xu, Yadi Bin, Tianjie Liu, Zhichao Li, Dan Guo, Yarui Li, Qiao Huang, Jun Lyu and Shuixiang He
    Citation: BMC Gastroenterology 2022 22:57
    Content type: Research article Published on:

  10. Type 2 isolated dextrogastria in conjunction with protrusion of the right hemidiaphragm and hiatal hernia is an uncommon anomaly among all transpositions of the viscera. Clear diagnosis is not straightforward ...

    Authors: Shahid Aziz, Simone König, Haseeb Noor, Muhammad Nadeem, Rabaab Zahra and Faisal Rasheed
    Citation: BMC Gastroenterology 2022 22:56
    Content type: Case report Published on:

  12. Liver cirrhosis is a well-known risk factor of sepsis after emergent gastrointestinal (GI) endoscopy. Elective GI endoscopy before living donor liver transplantation (LDLT), however, may also carry the septic ...

    Authors: Yi-Chia Chan, Chao-Long Chen, Chih-Chi Wang, Chih-Che Lin, Chee-Chien Yong, King-Wah Chiu and Keng-Liang Wu
    Citation: BMC Gastroenterology 2022 22:54
    Content type: Research Published on:

  13. Congenital portosystemic shunts (CPSS) are rare vascular malformations and can be classified into extrahepatic and intrahepatic shunts. Extrahepatic CPSS, also termed Abernethy malformations are associated wit...

    Authors: Ludger Sieverding, Michael Hofbeck, Jörg Michel, Andreas Hornung, Christian Scheckenbach, Gerd Grözinger, Ekkehard Sturm, Steven W. Warmann and Anja Hanser
    Citation: BMC Gastroenterology 2022 22:53
    Content type: Case report Published on:

  14. Juxta-papillary duodenal diverticulum (JPDD) has been associated with obstructive jaundice and ascending cholangitis. Potential mechanisms include periampullary colonization of pathogenic bacteria and mechanic...

    Authors: Uday Shankar, Priyanka Bhandari, Ankur Panchal, David Weeks, Helen Wu, Fufei Chen, Narinder Maheshwari, Raghav Bansal, Aaron Walfish, Joel Baum, Priya A. Jamidar and Joshua Aron
    Citation: BMC Gastroenterology 2022 22:52
    Content type: Research article Published on:

  15. Postoperative pancreatic fistula (POPF) is a frequent complication after pancreaticoduodenectomy (PD). This study aimed to investigate the impact of Vater’s ampullary carcinoma (VAC) on clinically relevant POP...

    Authors: Yifei Yang, Xu Fu, Saisai Zhu, Zhenghua Cai, Yudong Qiu and Liang Mao
    Citation: BMC Gastroenterology 2022 22:51
    Content type: Research Published on:

  16. Fewer than 50% of patients with acute-on-chronic liver failure (ACLF) recover spontaneously, and ACLF has high mortality without liver transplantation. Oxidative stress has been shown to mediate hepatic inflam...

    Authors: Zhen Tian, Naijuan Yao, Yuchao Wu, Fei Wang and Yingren Zhao
    Citation: BMC Gastroenterology 2022 22:50
    Content type: Research article Published on:

  17. Sunitinib and pazopanib are both oral small molecule multityrosine kinase inhibitors (MTKI) used in the treatment of renal cell carcinoma (RCC). Hepatotoxicity or “liver injury” is the most important adverse e...

    Authors: Hana Studentova, Jindriska Volakova, Martina Spisarova, Anezka Zemankova, Kvetoslava Aiglova, Tomas Szotkowski and Bohuslav Melichar
    Citation: BMC Gastroenterology 2022 22:49
    Content type: Case report Published on:

  18. Irritable bowel syndrome (IBS) represents the most common functional disorder of the gastrointestinal tract. Many patients with IBS display complex gastrointestinal (GI) symptoms leading to overlapping diagnos...

    Authors: Sven H. Loosen, Karel Kostev, Markus S. Jördens, Tom Luedde and Christoph Roderburg
    Citation: BMC Gastroenterology 2022 22:48
    Content type: Research article Published on:

  20. Transcatheter arterial chemoembolization (TACE) via the inferior phrenic artery has been recognized to have its own therapeutic role without causing serious procedural complications. We report a case of diaphr...

    Authors: Ji Soo Kim, Hyoung Nam Lee, Woong Hee Lee and Suk Hyun Bae
    Citation: BMC Gastroenterology 2022 22:46
    Content type: Case report Published on:

  21. Previous studies have shown that tumor mutation burden (TMB) in cancer is associated with prognosis. The purpose of this study is to identify TMB related genes in gastric cancer (GC) and to explore their progn...

    Authors: Wenjie Li, Kezhi Zhou, Mengting Li, Qian Hu, Wanhui Wei, Lan Liu and Qiu Zhao
    Citation: BMC Gastroenterology 2022 22:45
    Content type: Research Published on:

  22. Prevalence of inflammatory bowel disease (IBD) is increasing in China. The EXPLORE study evaluated the incidence and indicators of suboptimal responses to first-line anti-tumor necrosis factor (TNF) in patient...

    Authors: Ji Li, Zhanju Liu, Pinjin Hu, Zhonghui Wen, Qian Cao, Xiaoping Zou, Yan Chen, Yingde Wang, Jie Zhong, Xizhong Shen, Dirk Demuth, Olga Fadeeva, Li Xie, Jun Chen and Jiaming Qian
    Citation: BMC Gastroenterology 2022 22:44
    Content type: Research Published on:

  23. Irritable bowel syndrome (IBS) is a functional bowel disease that is characterized by abdominal pain, discomfort, and changes in the frequency and form of stool without any organic pathology. In this study, th...

    Authors: Emin Gemcioglu, Nuray Yılmaz Cakmak, Salih Baser, Servet Kocaoz and Osman Ersoy
    Citation: BMC Gastroenterology 2022 22:43
    Content type: Research Published on:

  25. Currently, the minimally invasive “Step-up” surgical strategy is still the main treatment for infected pancreatic necrosis (IPN). However, indiscriminate implementation of the “Step-up” strategy can lead to in...

    Authors: Zhi Zheng, Jiongdi Lu, Feng Cao, Yixuan Ding, Yulin Guo, Wentong Mei, Yuanxu Qu, Shuang Liu, Haichen Sun, Yeqing Cui, Ang Li and Fei Li
    Citation: BMC Gastroenterology 2022 22:41
    Content type: Study protocol Published on:

  26. Nonthyroidal illness syndrome (NTIS) is common in critical illness and is associated with poor prognosis. The aim of this study was to find the prevalence, charateristics, and prognosis of NTIS and its correla...

    Authors: Cheng Qu, Zehua Duan, Xiaojia Xiao, Mei Wei, Kun Gao, Xianqiang Yu, Lu Ke, Zhihui Tong and Weiqin Li
    Citation: BMC Gastroenterology 2022 22:40
    Content type: Research article Published on:

  27. A simple serum biomarker for clinical outcome in patients with ulcerative colitis (UC) remains an unmet need. Some studies have shown an association between C-reactive protein (CRP)-albumin ratio (CAR) and pro...

    Authors: Shinya Furukawa, Sen Yagi, Kana Shiraishi, Teruki Miyake, Kazuhiro Tange, Yu Hashimoto, Shogo Kitahata, Tomoe Kawamura, Tomoyuki Ninomiya, Kenichirou Mori, Seiyuu Suzuki, Naozumi Shibata, Hidehiro Murakami, Katsuhisa Ohashi, Aki Hasebe, Hideomi Tomida…
    Citation: BMC Gastroenterology 2022 22:39
    Content type: Research Published on:

  28. Coronavirus disease 2019 (COVID-19) has become a global pandemic, with healthcare workers at a high risk of exposure. During this pandemic, endoscopists must wear personal protective equipment (PPE), including...

    Authors: Jong Yoon Lee, Yeo Wool Kang, Myeongseok Koh, Dong Kyun Kim, Jin Seok Jang and Jong Hoon Lee
    Citation: BMC Gastroenterology 2022 22:38
    Content type: Research Published on:

  29. Noninvasive diagnostic technologies that can dynamically monitor changes in liver inflammation are highly important for the management of chronic hepatitis B (CHB) patients and thus warrant further exploration...

    Authors: Kaiping Jiang, Lei Zhang, Jianhong Li, Hongtao Hu, Qinghua Huang, Tengyu Qiu, Xiaoai Mo, Jian Ren, Wenqiang Guo, Yin Tao, Haijun Cui, Ying Zuo, Xuli Chen, Youqing Xie, Yanxing Li, Haimin Liang…
    Citation: BMC Gastroenterology 2022 22:37
    Content type: Research Published on:

  30. Crohn’s disease (CD)-related rectovaginal fistulas (RVFs) and anovaginal fistulas (AVFs) are rare, debilitating conditions that present a substantial disease and treatment burden for women. This systematic lit...

    Authors: Kristy Iglay, Dimitri Bennett, Michael D. Kappelman, Sydney Thai, Molly Aldridge, Chitra Karki and Suzanne F. Cook
    Citation: BMC Gastroenterology 2022 22:36
    Content type: Research article Published on:

  31. The right colon is difficult to cleanse compared with other colon segments. This post hoc analysis of two randomised clinical trials (MORA and NOCT) examined whether 1L polyethylene glycol (PEG) NER1006 and tw...

    Authors: Jonathan Manning, Juha Halonen, Sandra Jose Cheriyamkunnel and Marco Antonio Álvarez-González
    Citation: BMC Gastroenterology 2022 22:35
    Content type: Research Published on:

  32. Transplantation offers the best survival for patients with end stage organ disease. Transplant of hepatitis C virus (HCV) nucleic acid test (NAT) positive organs into negative recipients is a novel strategy th...

    Authors: Waleed Alghamdi, Khaled Lotfy, Corinne Weernink, Enad Alsolami, Anthony Jevnikar, Patrick Luke, Anton Skaro, Karim Qumosani, Mayur Brahmania, Paul Marotta, Syed M. Hosseini-Moghaddam and Anouar Teriaky
    Citation: BMC Gastroenterology 2022 22:34
    Content type: Research Published on:

  34. Intestinal pseudo-obstruction (IPO) accompanied by hepatobiliary dilatation and ureterohydronephrosis is extremely rare in systemic lupus erythematosus (SLE). This triad is also called visceral muscle dysmotil...

    Authors: Junxian Wen, Weijie Chen, Lu Gao, Xiaoyuan Qiu and Guole Lin
    Citation: BMC Gastroenterology 2022 22:32
    Content type: Case report Published on:

  36. The prognosis difference based on the depth of tumor muscularis propria invasion in gastric cancer (GC) was still debated, and therapy strategy for stage IB GC patient required further investigation.

    Authors: Kang He, Cheng Chen, Lei Xia, Lixiang Si, Xiaohua Pan, Zijian Sun, Yajing Wang, Yingying Jiang, Yue Shi, Bin Zhou, Shuaiyu Wang, Jing Han, Bo Shen, Guoren Zhou, Jianwei Lu and Xiaohua Wang
    Citation: BMC Gastroenterology 2022 22:30
    Content type: Research Published on:

  37. Malignant ascites is a manifestation of end stage events in a variety of cancers and is associated with significant morbidity. Epigenetic modulators play a key role in cancer initiation and progression, among ...

    Authors: Li Du, Dongyuan Wang, Xiuqi Wei, Chang Liu, Zhuanglong Xiao, Wei Qian, Yuhu Song and Xiaohua Hou
    Citation: BMC Gastroenterology 2022 22:29
    Content type: Research Published on:

  39. Although marginal donor livers expand the donor pool, an ideal method for quantitatively evaluating the quality of donor livers has not been developed. This study aimed to explore the feasibility of indocyanin...

    Authors: Liyu Shan, Huan Chen, Lifei Yang, Zhe Feng, Yue Wang, Rongfeng Wang, Nana Zhang, Rongqian Wu, Yi Lv and Tao Ma
    Citation: BMC Gastroenterology 2022 22:27
    Content type: Research Published on:

  40. Sarcopenia is an age-related syndrome that may have negative impact on surgical outcomes and long-term survival of patients with gastric cancer. Serum creatinine/cystatin C (Cr/CysC) ratio has attracted attent...

    Authors: Jing Sun, Hui Yang, Wentao Cai, Jingwei Zheng, Ningzhe Shen, Xinxin Yang, Bujian Pan, Weiteng Zhang, Xiaodong Chen and Xian Shen
    Citation: BMC Gastroenterology 2022 22:26
    Content type: Research Published on:

  41. Gastric cancer (GC) is one of the deadliest tumours due to its ability to metastasize. The Epithelial–to-mesenchymal transition plays a crucial role in promoting the GC metastasis, which increases the migratio...

    Authors: Xiao-tian Chang, Hui Wu, Hui-lin Li, Hong-lei Li and Ya-bing Zheng
    Citation: BMC Gastroenterology 2022 22:25
    Content type: Research Published on:

  43. The association between iron-metabolism-related variables and liver fibrosis in chronic hepatitis C and nonalcoholic fatty liver disease is now well known. However, the relationship has not been extensively st...

    Authors: Qingling Chen, Min Gao, Hang Yang, Ling Mei, Rui Zhong, Ping Han, Peiyan Liu, Lili Zhao, Jing Wang and Jia Li
    Citation: BMC Gastroenterology 2022 22:23
    Content type: Research Published on:

  44. Therapy regimens used in patients with inflammatory Bowel Disease (IBD) have been associated with enhanced risk of viral infections or viral reactivation. Moreover, it is uncertain whether IBD patients have in...

    Authors: Lisanne Rieker, Johannes Hofer, Golo Petzold, Volker Ellenrieder and Ahmad Amanzada
    Citation: BMC Gastroenterology 2022 22:22
    Content type: Case report Published on:

  45. Proton pump inhibitors (PPIs), including potassium ion-competitive acid blocker, are widely used worldwide and are often used for long periods of time. However, in recent years, potential side effects associat...

    Authors: Mariko Hojo, Daisuke Asaoka, Yuji Shimada, Shuko Nojiri and Akihito Nagahara
    Citation: BMC Gastroenterology 2022 22:21
    Content type: Study protocol Published on:

  46. Emerging evidence suggests that cardiometabolic index (CMI) is closely related to diabetes, hypertension, stroke, cardiovascular disease, and kidney disease, which implies that CMI has the value as an indicato...

    Authors: Jiawang Zou, Hailan Xiong, Huimin Zhang, Chong Hu, Song Lu and Yang Zou
    Citation: BMC Gastroenterology 2022 22:20
    Content type: Research Published on:

  47. During a global crisis like the current COVID-19 pandemic, delayed admission to hospital in cases of emergent medical illness may lead to serious adverse consequences. We aimed to determine whether such delaye...

    Authors: Amitai Bickel, Samer Ganam, Ibrahim Abu Shakra, Inbal Farkash, Rola Francis, Nour Karra, Fahed Merei, Isaac Cohen and Eli Kakiashvili
    Citation: BMC Gastroenterology 2022 22:19
    Content type: Research Published on:

  48. In this trial, we investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD).

    Authors: Zahra Akbari Namvar, Reza Mahdavi, Masood Shirmohammadi and Zeinab Nikniaz
    Citation: BMC Gastroenterology 2022 22:18
    Content type: Research Published on:

  49. We report the first case of a patient affected by peritoneal metastases from colon cancer, arising in the context of Lynch syndrome with pathological complete response. The patient was treated with immunothera...

    Authors: Marco Tonello, Floriana Nappo, Loretta Vassallo, Rosa Di Gaetano, Carla Davoli, Elisa Pizzolato, Ottavia De Simoni, Cristina Tassinari, Antonio Scapinello, Pierluigi Pilati, Fotios Loupakis, Sara Lonardi and Antonio Sommariva
    Citation: BMC Gastroenterology 2022 22:17
    Content type: Case report Published on:

  50. Recent studies have confirmed that combined surgery and anti-TNF therapy could improve outcomes in patients with perianal fistulising Crohn’s disease (PFCD). However, the optimal timing for infliximab infusion...

    Authors: Ping Zhu, Jin-fang Sun, Yun-fei Gu, Hong-jin Chen, Min-min Xu, You-ran Li and Bo-lin Yang
    Citation: BMC Gastroenterology 2022 22:15
    Content type: Research article Published on:
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BMC Gastroenterology

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