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  1. Rett syndrome (RTT) is a neurological disorder mainly caused by mutations in MeCP2 gene. It has been shown that MeCP2 impairments can lead to cytokine dysregulation due to MeCP2 regulatory role in T-helper and T-...

    Authors: Francesco Strati, Antonio Calabrò, Claudio Donati, Claudio De Felice, Joussef Hayek, Olivier Jousson, Silvia Leoncini, Daniela Renzi, Lisa Rizzetto, Carlotta De Filippo and Duccio Cavalieri
    Citation: BMC Gastroenterology 2018 18:57
  2. Several pull-through procedures have been described for Hirschsprung disease (HSCR) with varying functional outcomes. The voluntary bowel movement (VBM) and the absence of s...

    Authors: Amira Widyasari, Winona Alda Pavitasari, Andi Dwihantoro and Gunadi
    Citation: BMC Gastroenterology 2018 18:56

    The Correction to this article has been published in BMC Gastroenterology 2021 21:357

    The Correction to this article has been published in BMC Gastroenterology 2018 18:110

  3. An intra-abdominal abscess can sometimes become serious and difficult to treat. The current standard treatment strategy for intra-abdominal abscess is percutaneous imaging-guided drainage. However, in cases of...

    Authors: Shinichi Morita, Kenya Kamimura, Takeshi Suda, Chiyumi Oda, Takahiro Hoshi, Tsutomu Kanefuji, Kazuyoshi Yagi and Shuji Terai
    Citation: BMC Gastroenterology 2018 18:55
  4. Helicobacter pylori (H. pylori) infection can induce individual inflammatory and immune reactions which associated with extra-digestive disorders. Our aim is to investigate the association between H. pylori infec...

    Authors: Bo-Lin Pan, Chih-Fang Huang, Seng-Kee Chuah, Jui-Chin Chiang and Song-Seng Loke
    Citation: BMC Gastroenterology 2018 18:54
  5. Pancreatic duct obstructions are common in patients with pancreaticoduodenectomy. However, it is often neglected in follow up. This study was to review the outcomes of pancreatic duct obstruction and explore t...

    Authors: Lingfu Zhang, Dianrong Xiu, Chunhui Yuan, Bin Jiang and Zhaolai Ma
    Citation: BMC Gastroenterology 2018 18:53
  6. Pancreatic duct disruption is a challenging condition leading to pancreatic juice leakage and consequently to pancreatic fluid collections. The manifestations of pancreatic main duct leak include pseudocysts, ...

    Authors: Martino Gerosa, Marco Chiarelli, Angelo Guttadauro, Matilde De Simone, Fulvio Tagliabue, Melchiorre Costa, Sabina Terragni and Ugo Cioffi
    Citation: BMC Gastroenterology 2018 18:52
  7. Several studies have emerged indicating that sarcopenia is associated with nonalcoholic fatty liver disease, we aimed to systematically review and quantify the association between sacropenia and the histologic...

    Authors: Rui Yu, Qiangwei Shi, Lei Liu and Lidong Chen
    Citation: BMC Gastroenterology 2018 18:51
  8. Helicobacter pylori (H. pylori) infection is a worldwide threat to human health with high prevalence. In this study, we analyzed the relationship between latitude, average annual temperature, average daily sunshi...

    Authors: Chao Lu, Ye Yu, Lan Li, Chaohui Yu and Ping Xu
    Citation: BMC Gastroenterology 2018 18:50
  9. There are few reports about resection of portal vein (PV)/superior mesenteric vein (SMV) and reconstruction by using allogeneic vein. This case-control study was designed to explore the feasibility and safety ...

    Authors: Xing-mao Zhang, Jie Zhang, Hua Fan, Qiang He and Ren Lang
    Citation: BMC Gastroenterology 2018 18:49
  10. Epidermolysis bullosa (EB) constitutes a heterogenous group of rare multisystem genetically transmitted disorders comprising several blistering muco-cutaneous diseases with a monogenic basis and either autosom...

    Authors: Agata Michalak, Halina Cichoż-Lach, Beata Prozorow-Król, Leszek Buk and Monika Dzida
    Citation: BMC Gastroenterology 2018 18:47
  11. Bleeding after endoscopic submucosal dissection (ESD) in antithrombotic drug users is still one of the important issues to be solved. We performed scheduled second-look endoscopy (SLE) 5 days after ESD, when t...

    Authors: Koichi Izumikawa, Masaya Iwamuro, Tomoki Inaba, Shigenao Ishikawa, Kenji Kuwaki, Ichiro Sakakihara, Kumiko Yamamoto, Sakuma Takahashi, Shigetomi Tanaka, Masaki Wato and Hiroyuki Okada
    Citation: BMC Gastroenterology 2018 18:46
  12. Current treatment options for chronic hepatitis B (CHB) are pegylated interferon alpha and nucleoside analogues (NAs). NAs have relatively fewer side effects than interferon alpha, and generally well tolerated...

    Authors: Yue Ying, Yue-Kai Hu, Jia-Lin Jin, Ji-Ming Zhang, Wen-Hong Zhang and Yu-Xian Huang
    Citation: BMC Gastroenterology 2018 18:45
  13. Perianal fistula surgery can damage the anal sphincters which may cause faecal incontinence. By measuring regional pressures, 3D-HRAM potentially provides better guidance for surgical strategy in patients with...

    Authors: Richelle J. F. Felt-Bersma, Maarten S. Vlietstra, Paul F. Vollebregt, Ingrid J. M. Han-Geurts, Vera Rempe-Sorm, Grietje J. H. Vander Mijnsbrugge and Charlotte B. H. Molenaar
    Citation: BMC Gastroenterology 2018 18:44
  14. For patients with advanced gastric cancer (AGC), second-line chemotherapy regimen remains controversial. The efficacy and safety of irinotecan-containing doublet treatment and irinotecan monotherapy were compa...

    Authors: Liuting Yang, Xiaoyue Jiang, Han Yan, Yingying Li, Hongchao Zhen, Bingmei Chang, Seyed Kariminia and Qin Li
    Citation: BMC Gastroenterology 2018 18:43
  15. The primary purpose of this study was to compare Rome III and IV evaluation criteria for irritable bowel syndrome (IBS), functional dyspepsia (FD), and an overlap syndrome consisting of both IBS and FD by asse...

    Authors: Trent Edwards, Craig Friesen and Jennifer V. Schurman
    Citation: BMC Gastroenterology 2018 18:41
  16. Detection of human hepatitis B virus (HBV) DNA in the urine of patients with chronic hepatitis B infection (CHB) has been reported previously, suggesting urine could provide a potential route of horizontal HBV...

    Authors: Surbhi Jain, Ying-Hsiu Su, Yih-Ping Su, Sierra McCloud, Ruixia Xue, Tai-Jung Lee, Shu-Chuan Lin, Selena Y. Lin, Wei Song, Jamin D. Steffen and Chi-Tan Hu
    Citation: BMC Gastroenterology 2018 18:40
  17. Endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic sphincterotomy (ES) has become well established as a modality for the management of common bile duct stones (CBDS), especially in the setti...

    Authors: Tatenda C. Nzenza, Yahya Al-Habbal, Glen R. Guerra, S. Manolas, Tuck Yong and Trevor McQuillan
    Citation: BMC Gastroenterology 2018 18:39
  18. The incidence of biliary tract pathology is growing with an age-related trend, and progresses as the population ages. Endoscopic Retrograde Cholangiopancreatography (ERCP) represents the gold standard for trea...

    Authors: Marianna Galeazzi, Paolo Mazzola, Breanna Valcarcel, Giuseppe Bellelli, Marco Dinelli, Giulio Maria Pasinetti and Giorgio Annoni
    Citation: BMC Gastroenterology 2018 18:38
  19. Unfortunately, after publication of this article [1], it was noticed that the names of the second and third authors were incorrectly displayed, respectively, as Glauce Hiromi Yonaminez and Carla Aline Satiro. ...

    Authors: Maraci Rodrigues, Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro
    Citation: BMC Gastroenterology 2018 18:36

    The original article was published in BMC Gastroenterology 2018 18:15

  20. Endoscopic submucosal dissection (ESD) is a standard treatment for early gastric cancer. A new multi-functional ESD device was developed to achieve complete ESD with a single device. A metal plate attached to ...

    Authors: Mitsuru Esaki, Sho Suzuki, Yasuyo Hayashi, Azusa Yokoyama, Shuichi Abe, Taizo Hosokawa, Haruei Ogino, Hirotada Akiho, Eikichi Ihara and Yoshihiro Ogawa
    Citation: BMC Gastroenterology 2018 18:35
  21. Geranylgeranylacetone (GGA), an anti-ulcer drug widely used in Japan, has attracted interest because of its various therapeutic effects. Therefore, we investigated the effects of GGA on human hepatic stellate ...

    Authors: Takemasa Senoo, Ryu Sasaki, Yuko Akazawa, Tatsuki Ichikawa, Satoshi Miuma, Hisamitsu Miyaaki, Naota Taura and Kazuhiko Nakao
    Citation: BMC Gastroenterology 2018 18:34
  22. Chronic abdominal pain is a common worldwide problem and known to be associated with psychological problems. This study evaluated the association between abdominal pain-predominant functional gastrointestinal ...

    Authors: Nishadi Ranasinghe, Niranga Manjuri Devanarayana, Shaman Rajindrajith, Madusanka S. Perera, Samudu Nishanthinie, Tania Warnakulasuriya and Piyanjali Thamesha de Zoysa
    Citation: BMC Gastroenterology 2018 18:33
  23. In patients with common bile duct stones (CBDS) and intact gallbladder, further management for the gallbladder after the CBDS clearance is still controversial. The relationship between gallbladder motility and...

    Authors: Tzung-Jiun Tsai, Hoi-Hung Chan, Kwok-Hung Lai, Chih-An Shih, Sung-Shuo Kao, Wei-Chih Sun, E-Ming Wang, Wei-Lun Tsai, Kung-Hung Lin, Hsien-Chung Yu, Wen-Chi Chen, Huay-Min Wang, Feng-Woei Tsay, Huey-Shyan Lin, Jin-Shiung Cheng and Ping-I Hsu
    Citation: BMC Gastroenterology 2018 18:32
  24. Cyclooxygenase (COX) activity is increased in endoscopic normal colonic mucosa from patients with colorectal neoplasia (CRN). COX-2 is thought to be the predominant COX isozyme involved in neoplasia. Meanwhile...

    Authors: Thorbjørn Søren Rønn Jensen, Badar Mahmood, Morten Bach Damm, Marie Balslev Backe, Mattias Salling Dahllöf, Steen Seier Poulsen, Mark Berner Hansen and Niels Bindslev
    Citation: BMC Gastroenterology 2018 18:31
  25. Anal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for overall survival. The aim of this study was to evalu...

    Authors: Paulo C. Soares, Eliana S. Abdelhay, Luiz Claudio S. Thuler, Bruno Moreira Soares, Samia Demachki, Gessica Valéria Rocha Ferro, Paulo P. Assumpção, Leticia Martins Lamarão, Luis Felipe Ribeiro Pinto and Rommel Mario Rodríguez Burbano
    Citation: BMC Gastroenterology 2018 18:30
  26. Of all older patients that opt for elective colorectal surgery, approximately one-third has one or more postoperative complications, particularly those patients with a low cardiorespiratory fitness (ventilator...

    Authors: Annefleur E. M. Berkel, Bart C. Bongers, Marie-Janne S. van Kamp, Hayke Kotte, Paul Weltevreden, Frans H. C. de Jongh, Michiel M. M. Eijsvogel, A. N. Machteld Wymenga, Marloes Bigirwamungu-Bargeman, Job van der Palen, Marc J. van Det, Nico L. U. van Meeteren and Joost M. Klaase
    Citation: BMC Gastroenterology 2018 18:29
  27. Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence o...

    Authors: Stian Magnus Staurung Orlien, Nejib Yusuf Ismael, Tekabe Abdosh Ahmed, Nega Berhe, Trine Lauritzen, Borghild Roald, Robert David Goldin, Kathrine Stene-Johansen, Anne Margarita Dyrhol-Riise, Svein Gunnar Gundersen, Marsha Yvonne Morgan and Asgeir Johannessen
    Citation: BMC Gastroenterology 2018 18:27
  28. The primary function of the intestines is the absorption of water and nutrients. Although our knowledge about these processes on the cellular level is extensive, a number of important intracellular elements re...

    Authors: Satu Oltedal, Ivar Skaland, Jodi Maple-Grødem, Kjersti Tjensvoll, Emiel A. M. Janssen, Bjørnar Gilje, Rune Smaaland, Reino Heikkilä and Oddmund Nordgård
    Citation: BMC Gastroenterology 2018 18:26
  29. It has been reported that some single-nucleotide polymorphisms (SNPs) in lipid regulators such as apolipoproteins and cell surface molecules for hepatitis C virus (HCV) entry into hepatocytes are associated wi...

    Authors: Rie Harada, Masako Kimura, Yasushi Sato, Tatsuya Taniguchi, Tetsu Tomonari, Takahiro Tanaka, Hironori Tanaka, Naoki Muguruma, Hirohiko Shinomiya, Hirohito Honda, Issei Imoto, Masahiro Sogabe, Toshiya Okahisa and Tetsuji Takayama
    Citation: BMC Gastroenterology 2018 18:24
  30. Accelerated treatment strategy, including tight disease control and early aggressive therapy with immunosuppressives (IS) and biological agents have become increasingly common in inflammatory bowel disease (IB...

    Authors: Zsuzsanna Kurti, Akos Ilias, Lorant Gonczi, Zsuzsanna Vegh, Petra Fadgyas-Freyler, Gyula Korponay, Petra A. Golovics, Barbara D. Lovasz and Peter L. Lakatos
    Citation: BMC Gastroenterology 2018 18:23
  31. Serum IgG and IgA food antibodies have been used for dietary advice to subjects with gastrointestinal symptoms and perceived food intolerance, but the role of these antibodies in mediating intolerance is contr...

    Authors: Anne Stine Kvehaugen, Dag Tveiten and Per G. Farup
    Citation: BMC Gastroenterology 2018 18:22
  32. Although subacute and chronic gastrointestinal symptoms are very common in primary care, epidemiological date are sparse. The aim of the study was to examine and quantify the prevalence of subacute and chronic...

    Authors: Maria Avramidou, Felix Angst, Jules Angst, André Aeschlimann, Wulf Rössler and Ulrich Schnyder
    Citation: BMC Gastroenterology 2018 18:21
  33. The gastric microbiota has recently been implicated in the causation of organic/structural gastroduodenal diseases (gastric and duodenal ulcers, gastric cancer) in patients with Helicobacter pylori (H. pylori) in...

    Authors: Verima Pereira, Philip Abraham, Sivaramaiah Nallapeta and Anjali Shetty
    Citation: BMC Gastroenterology 2018 18:20
  34. Peripheral neuropathy is one most common, limiting and invalidating neurological symptom in subjects with hepatitis C virus and mixed cryoglobulinemia. Notably, the medical therapy proposed to eradicate HCV, c...

    Authors: Rita Moretti, Paola Caruso, Matteo Dal Ben, Silvia Gazzin and Claudio Tiribelli
    Citation: BMC Gastroenterology 2018 18:19
  35. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) predict severity in various diseases. In this study, we evaluated the value of NLR and PLR as prognostic factors in acute pancreatiti...

    Authors: Seung Kook Cho, Saehyun Jung, Kyong Joo Lee and Jae Woo Kim
    Citation: BMC Gastroenterology 2018 18:18
  36. The diagnosis of Barrett’s esophagus (BE) is disturbed by numerous factors, including correct gastroesophageal junction judgment, the initial location of the Z-line and the biopsy result above it. The acetic a...

    Authors: Yating Sun, Shiyang Ma, Li Fang, Jinhai Wang and Lei Dong
    Citation: BMC Gastroenterology 2018 18:17
  37. We present the first description of en bloc endoscopic submucosal dissection (ESD) for total circumferential Barrett’s adenocarcinoma, predominantly of the long-segment Barrett’s esophagus (LSBE), with a 2-year f...

    Authors: Miki Kaneko, Akira Mitoro, Motoyuki Yoshida, Masayoshi Sawai, Yasushi Okura, Masanori Furukawa, Tadashi Namisaki, Kei Moriya, Takemi Akahane, Hideto Kawaratani, Mitsuteru Kitade, Kousuke Kaji, Hiroaki Takaya, Yasuhiko Sawada, Kenichiro Seki, Shinya Sato…
    Citation: BMC Gastroenterology 2018 18:16
  38. Compliance with a gluten-free diet (GFD) is difficult at all ages but particularly for teenagers due to social, cultural, economic, and practical pressures. The multidisciplinary team responsible for the treat...

    Authors: Maraci Rodrigues, Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro
    Citation: BMC Gastroenterology 2018 18:15

    The Correction to this article has been published in BMC Gastroenterology 2018 18:36

  39. Endoscopic retrograde cholangiography using a short double-balloon endoscope (DB-ERC) is a promising minimally-invasive method for accessing hepaticojejunostomy (HJ) anastomosis in patients with surgically alt...

    Authors: Sho Mizukawa, Koichiro Tsutsumi, Hironari Kato, Shinichiro Muro, Yutaka Akimoto, Daisuke Uchida, Kazuyuki Matsumoto, Takeshi Tomoda, Shigeru Horiguchi and Hiroyuki Okada
    Citation: BMC Gastroenterology 2018 18:14
  40. Dyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The...

    Authors: Abdurahaman Seid, Zemenu Tamir and Wondmagegn Demsiss
    Citation: BMC Gastroenterology 2018 18:13
  41. Slingshot homolog-1 (SSH1) plays an important role in pathological processes, including in the occurrence and development of tumours. The purpose of this study was to determine whether SSH1 is a key biomarker ...

    Authors: Yusufu Maimaiti, Maimaitiaili Maimaitiming, Yiliang Li, Saifuding Aibibula, Azatijiang Ainiwaer, Aikebaier Aili, Zhenzhu Sun and Kelimu Abudureyimu
    Citation: BMC Gastroenterology 2018 18:12
  42. Nutrition support is a common means for patients with gastric cancer, especially for those undergoing elective surgery. Recently, enteral immunonutrition (EIN) was increasingly found to be more effective than ...

    Authors: Ying Cheng, Junfeng Zhang, Liwei Zhang, Juan Wu and Zhen Zhan
    Citation: BMC Gastroenterology 2018 18:11
  43. Different clinical behaviour influences the importance of differentiating focal nodular hyperplasia (FNH) from other focal liver lesions (FLLs). The aim of this study was to compare the efficacy of contrast-en...

    Authors: Tomasz K. Nowicki, Karolina Markiet, Ewa Izycka-Swieszewska, Katarzyna Dziadziuszko, Michal Studniarek and Edyta Szurowska
    Citation: BMC Gastroenterology 2018 18:10
  44. Mesenteric inflammatory veno-occlusive disease (MIVOD) is difficult to diagnose because of its rarity, nonspecific clinical findings, and frequent confusion with other diseases including inflammatory bowel dis...

    Authors: Yosuke Yamada, Ken Sugimoto, Yashiro Yoshizawa, Yoshifumi Arai, Yoshiro Otsuki, Tomio Arai, Yasuyuki Kobayashi, Yoshihiko Sato and Yoshisuke Hosoda
    Citation: BMC Gastroenterology 2018 18:9
  45. Gastroesophageal reflux disease (GERD) is a factor that has a significant negative impact on the quality of life (QoL). Vertebral fractures and/or spinal malalignment may influence the frequency of GERD. Howev...

    Authors: Tetsuro Ohba, Shigeto Ebata, Kensuke Koyama and Hirotaka Haro
    Citation: BMC Gastroenterology 2018 18:8

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