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  1. Advanced pancreatic cancer is accompanied not only by bile duct obstruction, but also occasionally by duodenal obstruction. With new advances in chemotherapy and improvement in the management of stent dysfunct...

    Authors: Kazuyuki Matsumoto, Hironari Kato, Shigeru Horiguchi, Koichiro Tsutsumi, Yosuke Saragai, Saimon Takada, Sho Mizukawa, Shinichiro Muro, Daisuke Uchida, Takeshi Tomoda and Hiroyuki Okada
    Citation: BMC Gastroenterology 2018 18:157
    Content type: Research article Published on:

  3. Symptom based referral criteria for colorectal cancer (CRC) detection are the cornerstone of the strategy to improve prognosis in CRC. In 2017, the National Institute for Health and Care Excellence (NICE) upda...

    Authors: Jesús-Miguel Herrero, Pablo Vega, María Salve, Luis Bujanda and Joaquín Cubiella
    Citation: BMC Gastroenterology 2018 18:155
    Content type: Research article Published on:

  6. Perioperative serum potassium levels are closely associated with postoperative clinical outcomes after gastrointestinal surgery. The aim of our retrospective study was to identify the prevalence and risk facto...

    Authors: Qianqian Zhu, Xianlong Li, Fang Tan, Yingqing Deng, Chulian Gong, Jingping Hu, Pinjie Huang and Shaoli Zhou
    Citation: BMC Gastroenterology 2018 18:152
    Content type: Research article Published on:

  7. Endoscopic ultrasonography-guided fine-needle biopsy (EUS-FNB) may facilitate tissue acquisition for a definitive diagnosis of gastrointestinal subepithelial tumors (SETs). This study aimed to determine the di...

    Authors: Do Hoon Kim, Gwang Ha Kim, Chang Min Cho, Chang Hwan Park, Soo-Young Na, Tae Hyeon Kim, Yu Kyung Cho, Ji Hyun Kim and Dong-Wan Seo
    Citation: BMC Gastroenterology 2018 18:151
    Content type: Research article Published on:

  8. To overcome duodenobiliary reflux induced by biliary stents, antireflux valve (ARV) biliary stents have been developed and showed improvement in stent patency. However, negative study results have also been re...

    Authors: Chang-Il Kwon, Jong Pil Moon, Ho Yun, Seok Jeong, Dong Hee Koh, Woo Jung Lee, Kwang Hyun Ko and Dae Hwan Kang
    Citation: BMC Gastroenterology 2018 18:150
    Content type: Research article Published on:

  9. Gastrointestinal complications are the main cause of death in patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Available treatments often restore biochemical homeostasis, but fail t...

    Authors: Rana Yadak, Max V. Boot, Niek P. van Til, Dominique Cazals-Hatem, Armin Finkenstedt, Elly Bogaerts, Irenaeus F. de Coo and Marianna Bugiani
    Citation: BMC Gastroenterology 2018 18:149
    Content type: Research article Published on:

  10. Existing data about the prognostic value of absolute count of blood cells in gastric cancer was limited. Thus, the present study aims to investigate the prognostic value of absolute count of white blood cell (...

    Authors: Fan Feng, Gaozan Zheng, Qiao Wang, Shushang Liu, Zhen Liu, Guanghui Xu, Fei Wang, Man Guo, Xiao Lian and Hongwei Zhang
    Citation: BMC Gastroenterology 2018 18:148
    Content type: Research article Published on:

  11. This study is to investigate the association between the hepatic expression of Yin Yang 1 (YY1) and the progression of non-alcoholic fatty liver disease (NAFLD) in patients undergoing bariatric surgery.

    Authors: Xianwen Yuan, Jun Chen, Qi Cheng, Yinjuan Zhao, Pengzi Zhang, Xiaoyan Shao, Yan Bi, Xiaolei Shi, Yitao Ding, Xitai Sun and Bin Xue
    Citation: BMC Gastroenterology 2018 18:147
    Content type: Research article Published on:

  12. We aimed to study the epidemiology and risk factors, including exposure to emotional stress, for constipation in Indonesian children and adolescents of 10–17 year age group.

    Authors: Hanifah Oswari, Fatima Safira Alatas, Badriul Hegar, William Cheng, Arnesya Pramadyani, Marc Alexander Benninga and Shaman Rajindrajith
    Citation: BMC Gastroenterology 2018 18:146
    Content type: Research article Published on:

  14. Pyogenic liver abscess(PLA) has become common in patients with diabetes mellitus (DM), but it is unclear whether differences exist between patients with and without DM. A retrospective study was performed to i...

    Authors: Wenfei Li, Hongjie Chen, Shuai Wu and Jie Peng
    Citation: BMC Gastroenterology 2018 18:144
    Content type: Research article Published on:

  15. Pancreatic pseudocyst (PPC) is a common complication of acute and chronic pancreatitis. To our knowledge no study has systematically reported the risk factors for the formation, intervention and recurrence of ...

    Authors: Jie-hui Tan, Lei Zhou, Rong-chang Cao and Guo-wei Zhang
    Citation: BMC Gastroenterology 2018 18:143
    Content type: Research article Published on:

  16. Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed drugs and can cause drug-induced liver injury. Although patients with drug-induced liver injury from NSAIDs often recover spontaneously,...

    Authors: Wen Xie, Qi Wang, Yuanjiao Gao and Calvin Q. Pan
    Citation: BMC Gastroenterology 2018 18:142
    Content type: Case report Published on:

  17. With the rising demands for pancreas transplantation, surgeons are trying to extend the donors pool and set up a more appropriate assessment system. We aim to evaluate the effect of donor hypertension on recip...

    Authors: Zhen-Hua Hu, Yang-Jun Gu, Wen-Qi Qiu, Jie Xiang, Zhi-Wei Li, Jie Zhou and Shu-Sen Zheng
    Citation: BMC Gastroenterology 2018 18:141
    Content type: Research article Published on:

  18. Vedolizumab is safe and effective in adult patients with Crohn’s disease (CD) and ulcerative colitis (UC); however, data in children with inflammatory bowel disease (IBD) are scarce. Therefore, we evaluated ve...

    Authors: Anna-Maria Schneider, Daniel Weghuber, Benjamin Hetzer, Andreas Entenmann, Thomas Müller, Georg Zimmermann, Sebastian Schütz, Wolf-Dietrich Huber and Judith Pichler
    Citation: BMC Gastroenterology 2018 18:140
    Content type: Research article Published on:

  19. Early onset pancreatic cancer (EOPC), i.e. pancreatic ductal adenocarcinoma (PDAC) occurring in patients below 50 years of age, is rare and there is limited information regarding risk factors, molecular basis ...

    Authors: Chara Ntala, Silvana Debernardi, Roger M. Feakins and Tatjana Crnogorac-Jurcevic
    Citation: BMC Gastroenterology 2018 18:139
    Content type: Research article Published on:

  20. Transarterial chemoembolization (TACE) is the recommended treatment for hepatocellular carcinoma (HCC) patients at Barcelona Clinic Liver Cancer (BCLC) B-stage, whereas sorafenib is an orally administered smal...

    Authors: Lin Li, Wenzhuo Zhao, Mengmeng Wang, Jie Hu, Enxin Wang, Yan Zhao and Lei Liu
    Citation: BMC Gastroenterology 2018 18:138
    Content type: Research article Published on:

  21. Although tolvaptan treatment improves hyponatremia, only few studies have investigated whether tolvaptan actually benefits the survival of cirrhotic patients. This study evaluated the impact of tolvaptan on si...

    Authors: Shuzhen Wang, Xin Zhang, Tao Han, Wen Xie, Yonggang Li, Hong Ma, Roman Liebe, Honglei Weng and Hui-Guo Ding
    Citation: BMC Gastroenterology 2018 18:137
    Content type: Research article Published on:

  22. IgG4-related disease (IgG4-RD) is a newly recognized autoimmune systemic disorder characterized by elevated levels of serum IgG4 and abundant infiltration of IgG4-positive plasmacytes in the affected organs. T...

    Authors: Xuexue Deng, Ronghua Fang, Jianshu Zhang and Rongqiong Li
    Citation: BMC Gastroenterology 2018 18:136
    Content type: Case report Published on:

  23. The use of immune-checkpoint inhibitors in cancer treatment has become increasingly common, resulting in an increase in the incidence of related side effects. Diarrhoea and colitis have been previously documen...

    Authors: Ryosuke Yamauchi, Toshihiro Araki, Keiichi Mitsuyama, Takaaki Tokito, Hidenobu Ishii, Shinichiro Yoshioka, Kotaro Kuwaki, Atsushi Mori, Tetsuhiro Yoshimura, Osamu Tsuruta and Takuji Torimura
    Citation: BMC Gastroenterology 2018 18:135
    Content type: Case report Published on:

  24. Successful H. pylori treatment requires the knowledge of local antimicrobial resistance. Data on the efficacy of H. pylori eradication regimens available in sub-Saharan Africa are scant, hence the optimal treatme...

    Authors: Jean Damascene Kabakambira, Celestin Hategeka, Cameron Page, Cyprien Ntirenganya, Vincent Dusabejambo, Jules Ndoli, Francois Ngabonziza, DeVon Hale, Claude Bayingana and Tim Walker
    Citation: BMC Gastroenterology 2018 18:134
    Content type: Research article Published on:

  25. Synchronous polypectomy in colonic malignancies is contentious due to the perceived risks of tumour implantation at polypectomy sites (PS). We assess the risks of tumour implantation after synchronous polypect...

    Authors: W. J. Tan, N. ZP. Ng, Y. D. Chen, Y. H. M. Chee, F. J. Foo, C. L. Tang and M. H. Chew
    Citation: BMC Gastroenterology 2018 18:133
    Content type: Research article Published on:

  26. Although many patients still have anxiety about upper gastrointestinal (GI) endoscopy, there have been few reports on the influence of distractions for a person who is going to undergo upper GI endoscopy soon....

    Authors: Masahiro Sogabe, Toshiya Okahisa, Yuka Adachi, Masanori Takehara, Shinichi Hamada, Jun Okazaki, Yasuteru Fujino, Akira Fukuya, Kaizo Kagemoto, Akihiro Hirao, Koichi Okamoto, Masahiko Nakasono and Tetsuji Takayama
    Citation: BMC Gastroenterology 2018 18:132
    Content type: Research article Published on:

  27. Alteration of the gut microbiota by repeated antibiotic treatment increases susceptibility to Clostridioides difficile infection. Faecal microbiota transplantation from donors with a normal microbiota effectively...

    Authors: Jillian R.-M. Brown, Burkhardt Flemer, Susan A. Joyce, Akbar Zulquernain, Donal Sheehan, Fergus Shanahan and Paul W. O’Toole
    Citation: BMC Gastroenterology 2018 18:131
    Content type: Research article Published on:

  28. Iguratimod is a novel anti-rheumatic drug with the capability of anti-cytokines as report goes. It has been reported that iguratimod is effective and safe for rheumatoid arthritis and other rheumatisms. As sid...

    Authors: Xiao-li Li, Xiao-Chang Liu, Yu-Lin Song, Ru-Tao Hong and Hai Shi
    Citation: BMC Gastroenterology 2018 18:130
    Content type: Case report Published on:

  31. A variety of extra-intestinal manifestations (EIMs), including hepatobiliary complications, are associated with inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) have been shown to play a potenti...

    Authors: Guo chao Niu, Lei Liu, Libo Zheng, Hong Zhang, David Q. Shih and Xiaolan Zhang
    Citation: BMC Gastroenterology 2018 18:127
    Content type: Research article Published on:

  32. Anorexia nervosa (AN) concerns approximately up to 1.8% of the pediatric female population. One of the complications that can occur in the course of this disease is acute liver failure. This study’s objective ...

    Authors: Katarzyna Górowska-Kowolik, Agata Chobot and Jarosław Kwiecień
    Citation: BMC Gastroenterology 2018 18:126
    Content type: Research article Published on:

  33. Endoscopic submucosal dissection (ESD) of the postoperative stomach (ESD-P) for early gastric cancer (EGC) is considered a technically difficult procedure. However, it is difficult to compare the outcomes of E...

    Authors: Mitsuru Esaki, Sho Suzuki, Yasuyo Hayashi, Azusa Yokoyama, Shuichi Abe, Taizo Hosokawa, Shinichi Tsuruta, Yosuke Minoda, Yoshitaka Hata, Haruei Ogino, Hirotada Akiho, Eikichi Ihara and Yoshihiro Ogawa
    Citation: BMC Gastroenterology 2018 18:125
    Content type: Research article Published on:

  34. Antibiotic-associated diarrhea (AAD) is a side-effect frequently associated with the use of broad spectrum antibiotics. Although a number of clinical studies show that co-administration of specific probiotics ...

    Authors: Valeria Agamennone, Cyrille A. M. Krul, Ger Rijkers and Remco Kort
    Citation: BMC Gastroenterology 2018 18:103
    Content type: Research article Published on:

  35. Currently, no standard of care or therapies have been established for patients with advanced HCC. We evaluated the efficacy and safety of conventional transarterial chemoembolization using gelatin sponges or m...

    Authors: Yi-Sheng Liu, Chia-Ying Lin, Ming-Tsung Chuang, Chia-Ying Lin, Yi-Shan Tsai, Chien-Kuo Wang and Ming-Ching Ou
    Citation: BMC Gastroenterology 2018 18:124
    Content type: Research article Published on:

  36. The mortality due to hemorrhage of esophageal varices (EV) is still high. The predominant cause for EV is liver cirrhosis, which has a high prevalence in Western Europe. Therefore, non-invasive screening marke...

    Authors: Birgit Tsaknakis, Rawan Masri, Ahmad Amanzada, Golo Petzold, Volker Ellenrieder, Albrecht Neesse and Steffen Kunsch
    Citation: BMC Gastroenterology 2018 18:123
    Content type: Research article Published on:

  37. Acute pancreatitis is an acute inflammation of the pancreas that varies in severity from mild to life threatening usually requiring hospitalization. The true incidence of drug-induced pancreatitis (DIP) is ind...

    Authors: Sana Chams, Skye El Sayegh, Mulham Hamdon, Sarwan Kumar and Vesna Tegeltija
    Citation: BMC Gastroenterology 2018 18:122
    Content type: Case report Published on:

  38. The vertical transmission of HBV from mothers to their infants at birth or in early infancy has a significant role in the endemicity of HBV infection. Tenofovir is one of the most potent anti-HBV agents with a...

    Authors: Wenhui Li, Li Jia, Xin Zhao, Xiaoyuan Wu and Hongxia Tang
    Citation: BMC Gastroenterology 2018 18:121
    Content type: Research article Published on:

  39. Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC). Nonetheless, the relevance o...

    Authors: Takahiro Shimoyama, Takayuki Yamamoto, Satoru Umegae and Koichi Matsumoto
    Citation: BMC Gastroenterology 2018 18:120
    Content type: Research article Published on:

  40. Stress is a common contributing factor for irritable bowel syndrome (IBS). This study was to evaluate the efficacy of the centralized health education program in improving the quality of life (QOL) of middle s...

    Authors: Shi-Cheng Zheng, Hui Gong, Yi-Ping Wang, Qiang Zhang, Li-Li Wang, Xue-Fen Liao, Dai-Wen He and Jing Wu
    Citation: BMC Gastroenterology 2018 18:119
    Content type: Research article Published on:

  41. Obesity is a global problem leading to reduced life expectancy, cardiovascular diseases, diabetes and many types of cancer. Even people willing to accept treatment only achieve a mean weight loss of about 5 kg...

    Authors: Marcus Hollenbach, Christiane Prettin, Felix Gundling, Wolfgang Schepp, Jochen Seufert, Jürgen Stein, Thomas Rösch, Jens Aberle, Jürgen Feisthammel, David Petroff and Albrecht Hoffmeister
    Citation: BMC Gastroenterology 2018 18:118
    Content type: Study protocol Published on:

  42. Anastomotic leakage (AL) is the most serious and common complication of surgery for rectal cancer, and associated risk factors remain unknown despite developments in laparoscopic surgery. The present study aim...

    Authors: Seiichi Shinji, Yoshibumi Ueda, Takeshi Yamada, Michihiro Koizumi, Yasuyuki Yokoyama, Goro Takahashi, Masahiro Hotta, Takuma Iwai, Keisuke Hara, Kohki Takeda, Mikihiro Okusa, Hayato Kan, Eiji Uchida and Hiroshi Yoshida
    Citation: BMC Gastroenterology 2018 18:117
    Content type: Research article Published on:

  43. Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal disorders worldwide, with relevant impact on the quality of life and health care costs.The aim of our study is to assess the pr...

    Authors: Irene Martinucci, Michela Natilli, Valentina Lorenzoni, Luca Pappalardo, Anna Monreale, Giuseppe Turchetti, Dino Pedreschi, Santino Marchi, Roberto Barale and Nicola de Bortoli
    Citation: BMC Gastroenterology 2018 18:116
    Content type: Research article Published on:

  44. Patients with familial adenomatous polyposis (FAP) frequently undergo colectomy to reduce the 70 to 90% lifetime risk of colorectal cancer. After risk-reducing colectomy, duodenal cancer and complications from...

    Authors: Danielle C. Sample, N. Jewel Samadder, Lisa M. Pappas, Kenneth M. Boucher, Wade S. Samowitz, Therese Berry, Michelle Westover, Deepika Nathan, Priyanka Kanth, Kathryn R. Byrne, Randall W. Burt and Deborah W. Neklason
    Citation: BMC Gastroenterology 2018 18:115
    Content type: Research article Published on:

  46. Non-alcoholic fatty liver disease (NAFLD) comprises non-progressive steatosis and non-alcoholic steatohepatitis (NASH), the latter of which may cause cirrhosis and hepatocellular carcinoma (HCC). As NAFLD dete...

    Authors: Tilman Kühn, Tobias Nonnenmacher, Disorn Sookthai, Ruth Schübel, Daniel Antonio Quintana Pacheco, Oyunbileg von Stackelberg, Mirja E. Graf, Theron Johnson, Christopher L. Schlett, Romy Kirsten, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor and Johanna Nattenmüller
    Citation: BMC Gastroenterology 2018 18:113
    Content type: Research article Published on:

  47. Previous studies have indicated that bile acid is associated with progression of liver cirrhosis. However, the particular role of specific bile acid in the development of liver cirrhosis is not definite. The p...

    Authors: Zhimin Liu, Zhifeng Zhang, Mei Huang, Xiaoping Sun, Bojia Liu, Qiyang Guo, Qingshan Chang and Zhijun Duan
    Citation: BMC Gastroenterology 2018 18:112
    Content type: Research article Published on:

  48. Graft-versus-host disease (GVHD) is a common complication of allo-hematopoietic stem cell transplantation (allo-HSCT). Endoscopic biopsy can provide a definitive diagnosis, but the optimal endoscopic approach ...

    Authors: Yuusaku Sugihara, Sakiko Hiraoka, Nobuharu Fujii, Shiho Takashima, Yasushi Yamasaki, Toshihiro Inokuchi, Masahiro Takahara, Kenji Kuwaki, Keita Harada, Takehiro Tanaka and Hiroyuki Okada
    Citation: BMC Gastroenterology 2018 18:111
    Content type: Research article Published on:

  49. After publication of the original article [1], the authors reported that the Acknowledgments section was incomplete. The full section is the following:

    Authors: Amira Widyasari, Winona Alda Pravitasari, Andi Dwihantoro and Gunadi
    Citation: BMC Gastroenterology 2018 18:110
    Content type: Correction Published on:

    The original article was published in BMC Gastroenterology 2018 18:56

  50. Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. Worldwide, 6.3 to 33% of the general populati...

    Authors: Bashu Dev Pardhe, Shreena Shakya, Anjeela Bhetwal, Jennifer Mathias, Puspa Raj Khanal, Roshan Pandit, Jyotsna Shakya, Hari Om Joshi and Sujan Babu Marahatta
    Citation: BMC Gastroenterology 2018 18:109
    Content type: Research article Published on:
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