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  1. Epstein-Barr virus-associated early gastric carcinoma with lymphoid stroma (EBV-GCLS) is a rare variant of early gastric carcinomas. Clinicopathological features of this variant remain obscure, especially in C...

    Authors: Yuqing Cheng, Xiaoli Zhou, Kequn Xu, Jin Huang and Qin Huang
    Citation: BMC Gastroenterology 2020 20:273
  2. Segmental absence of intestinal musculature (SAIM) is a rare cause of intestinal obstruction and perforation due to partial or complete defects in the intestinal muscularis propria in neonates and is occasiona...

    Authors: Kosuke Kashiwagi, Keisuke Jimbo, Kenji Hosoi, Go Miyano, Takahiro Kudo, Atsuyuki Yamataka and Toshiaki Shimizu
    Citation: BMC Gastroenterology 2020 20:272
  3. Patients with liver cirrhosis typically exhibit abnormal coagulation parameters in conventional coagulation tests (CCTs). Rotational thromboelastometry (ROTEM) is a holistic blood coagulation assay. This metho...

    Authors: Jessica Seeßle, Jan Löhr, Marietta Kirchner, Josefin Michaelis and Uta Merle
    Citation: BMC Gastroenterology 2020 20:271
  4. Reflux esophagitis (RE) and absence of Helicobacter pylori (non-H. pylori) are considered to be associated with the progression to long-segment Barrett’s esophagus (LSBE). However, it is difficult to assess this ...

    Authors: Genki Usui, Tomohiro Shinozaki, Toyohisa Jinno, Kazutoshi Fujibayashi, Teppei Morikawa, Toshiaki Gunji and Nobuyuki Matsuhashi
    Citation: BMC Gastroenterology 2020 20:270
  5. Adenomatous gallbladder polyps, premalignant lesions of the gallbladder, have fatal outcomes, whereas cholesterol polyps have benign features. Herein, we proposed a novel, predictive scoring model of adenomato...

    Authors: Eun-young Kim and Tae-ho Hong
    Citation: BMC Gastroenterology 2020 20:268
  6. A pyogenic liver abscess (PLA) represents a pus-filled cavity within the liver parenchyma caused by the invasion and multiplication of bacteria. The most common offender isolated from the PLA in children is Staph...

    Authors: Petar Rasic, Srdjan Bosnic, Zorica V. Vasiljevic, Slavisa M. Djuricic, Vesna Topic, Maja Milickovic and Djordje Savic
    Citation: BMC Gastroenterology 2020 20:267
  7. Helicobacter pylori is accounted as the most etiologic agent for digestive disorders, in particular, the most important of them i.e. peptic ulcer and gastric cancer. In the recent years, association of vacA genot...

    Authors: Masoud Keikha, Mohammad Ali-Hassanzadeh and Mohsen Karbalaei
    Citation: BMC Gastroenterology 2020 20:266
  8. MELD score and MELD score derivates are used to objectify and grade the risk of liver-related death in patients with liver cirrhosis. We recently proposed a new predictive model that combines serum creatinine ...

    Authors: Tomasz Dziodzio, Robert Öllinger, Wenzel Schöning, Antonia Rothkäppel, Radoslav Nikolov, Andrzej Juraszek, Paul V. Ritschl, Martin Stockmann, Johann Pratschke and Maximilian Jara
    Citation: BMC Gastroenterology 2020 20:265
  9. Postoperative pancreatic fistula (POPF) is a life-threatening postoperative complication. The aim of this study was to evaluate the efficacy of the fistula risk score (FRS) and preoperative body composition fa...

    Authors: Tomoyuki Abe, Hironobu Amano, Tsuyoshi Kobayashi, Keiji Hanada, Minoru Hattori, Masahiro Nakahara, Hideki Ohdan and Toshio Noriyuki
    Citation: BMC Gastroenterology 2020 20:264
  10. Chronic exposure to lead causes lead to accumulate mainly in the liver. In vivo studies have shown that lead toxicity is related to alterations in the inflammatory response. We aimed to evaluate the associatio...

    Authors: Tongluk Teerasarntipan, Roongruedee Chaiteerakij, Piyapan Prueksapanich and Duangporn Werawatganon
    Citation: BMC Gastroenterology 2020 20:263

    The Correction to this article has been published in BMC Gastroenterology 2021 21:108

  11. Delayed bowel obstruction due to seat belt injury is extremely rare. The delayed onset of nonspecific symptoms makes a timely diagnosis difficult. A deep understanding of the characteristics of this condition ...

    Authors: Xing-Bin Ma, Bao-Guang Hu, Wei Wang, Xian-Yong Cheng, Chun-Di Guan and Cheng-Xia Liu
    Citation: BMC Gastroenterology 2020 20:262
  12. Approximately 15% of all cancers are due to infection. The bacteria Helicobacter pylori is the single leading carcinogenic infectious agent and the main cause of stomach cancer. Prevalence of H. pylori, and, corr...

    Authors: Sydnee Crankshaw, Julia Butt, Jennifer M. Gierisch, Nadine J. Barrett, Sabrena Mervin-Blake, Kevin Oeffinger, Steven Patierno, Valarie Worthy, Ronald Godbee and Meira Epplein
    Citation: BMC Gastroenterology 2020 20:261
  13. Several DNA viruses are highly suspicious to have oncogenic effects in humans. This study investigates the presence of potentially oncogenic viruses such as SV40, JCV, BKV and EBV in patient-derived colorectal...

    Authors: Michael Gock, Marcel Kordt, Stephanie Matschos, Christina S. Mullins and Michael Linnebacher
    Citation: BMC Gastroenterology 2020 20:260
  14. The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated at approximately 5% of the population. Celiac disease (CD), dermatitis herpetiformis (DH), gluten a...

    Authors: Nazanin Taraghikhah, Sara Ashtari, Nastaran Asri, Bijan Shahbazkhani, David Al-Dulaimi, Mohammad Rostami-Nejad, Mostafa Rezaei-Tavirani, Mohammad Reza Razzaghi and Mohammad Reza Zali
    Citation: BMC Gastroenterology 2020 20:258
  15. Rapid and accurate diagnostic tools are needed for appropriate management of infectious diarrhea.

    Authors: Daisy Torres-Miranda, Hana Akselrod, Ryan Karsner, Alessandra Secco, Diana Silva-Cantillo, Marc O. Siegel, Afsoon D. Roberts and Gary L. Simon
    Citation: BMC Gastroenterology 2020 20:246
  16. Chronic active Epstein-Barr virus infection (CAEBV) is a rare disease, which is difficult to be differentiated from inflammatory bowel disease (IBD). To cause the attention, we present twelve cases of CAEBV in...

    Authors: Weijia Xu, Xiaoyun Jiang, Jiajie Chen, Qiqi Mao, Xianguang Zhao, Xu Sun, Liang Zhong and Lan Rong
    Citation: BMC Gastroenterology 2020 20:257
  17. Gastric cancer (GC) is the third leading cause of cancer-related mortality worldwide. Therefore, identifying the predictive factors for surgical morbidity, disease recurrence, and long-term survival is necessa...

    Authors: Hitomi Takechi, Nobuaki Fujikuni, Kazuaki Tanabe, Minoru Hattori, Hironobu Amano, Toshio Noriyuki and Masahiro Nakahara
    Citation: BMC Gastroenterology 2020 20:256
  18. Non-alcoholic fatty liver disease (NAFLD) is a frequent condition in obese patients and regularly progresses to non-alcoholic steatohepatitis (NASH) and subsequent cirrhosis. Histologic evaluation is the gold ...

    Authors: Sophia Marie-Therese Schmitz, Andreas Kroh, Tom Florian Ulmer, Julia Andruszkow, Tom Luedde, Jonathan Frederik Brozat, Ulf Peter Neumann and Patrick Hamid Alizai
    Citation: BMC Gastroenterology 2020 20:254
  19. Health care costs are growing faster than the rest of the global economy, according to the World Health Organization (WHO). Countries’ health expenditures include paying for general medicine, diagnostic proced...

    Authors: Larissa Akeme Nakano, Eduardo Luiz Rachid Cançado, Cleuber Esteves Chaves, Maria Cristina Vaz Madeira, Jéssica Toshie Katayose, Mariana Akemi Nabeshima, Victor Fossaluza, Gabriela Guimarães Uhrigshardt, Zheng Liting, Vanusa Barbosa Pinto, Flair José Carrilho and Suzane Kioko Ono
    Citation: BMC Gastroenterology 2020 20:253
  20. Hypereosinophilic syndrome (HES) is a very rare disease and usually treated with corticosteroids. Gastrointestinal (GI) cytomegalovirus (CMV) infection is also rare but frequent in patients with immunocompromi...

    Authors: Bin Luo, Chengxin Deng, Tieying Hou, Fangping Xu, Qianchao Liao, Yong Li and Junjiang Wang
    Citation: BMC Gastroenterology 2020 20:238
  21. Beta-thalassemia represents a heterogeneous group of haemoglobin inherited disorders, among the most common genetic diseases in the world, frequent in the Mediterranean basin. As beta-thalassemia patients’ sur...

    Authors: Alessandra Mangia, Davide Bellini, Umberto Cillo, Andrea Laghi, Giuseppe Pelle, Vanna Maria Valori and Eugenio Caturelli
    Citation: BMC Gastroenterology 2020 20:251

    The Commentary to this article has been published in BMC Gastroenterology 2020 20:409

  22. Controversies in terms of efficacy and postoperative advantages surround stapled esophagogastric anastomosis compared with the hand-sewn technique as a treatment for patients with esophageal cancer. The purpos...

    Authors: Seyed Ziaeddin Rasihashemi, Ali Ramouz, Samad Beheshtirouy and Hassan Amini
    Citation: BMC Gastroenterology 2020 20:250
  23. Alpha-fetoprotein (AFP) has been widely used for many years as a serum marker for hepatocellular carcinoma (HCC). However, AFP has been recognized as having poor sensitivity. More and more studies have conclud...

    Authors: Cheng Peng, Zhuonan Li, Zishan Xie, Zhanpeng Wang, Yanshuo Ye, Bo Li and Wei Li
    Citation: BMC Gastroenterology 2020 20:249
  24. Crystal storing histiocytosis is a rare disorder associated with monoclonal gammopathy. In this disease, monoclonal heavy and light chains accumulate in the lysosome of macrophages, leading to histiocytic reac...

    Authors: Adrien Contejean, Frédérique Larousserie, Didier Bouscary, Anthony Dohan, Bénédicte Deau-Fischer, Tali-Anne Szwebel, Marion Dhooge, Benoit Terris and Marguerite Vignon
    Citation: BMC Gastroenterology 2020 20:239
  25. Esophageal fistula and stricture is rare but life-threatening complication for esophageal cancer. The management of esophageal fistula and stricture remains challenging. We aimed to determine the safety, feasi...

    Authors: Yonghua Bi, Mengfei Yi, Zepeng Yu, Xinwei Han and Jianzhuang Ren
    Citation: BMC Gastroenterology 2020 20:248
  26. A gluten-free diet (GFD) is the only effective treatment for celiac patients and assessing adherence to this diet is important. Celiac disease Adherence Test (CDAT) is a valid English-language questionnaire th...

    Authors: Zeinab Nikniaz, Mohammad Asghari Jafarabadi, Saeideh Ghaffarifar, Zahra Saeedi, Zahra Akbari Namvar and Masood Shirmohammadi
    Citation: BMC Gastroenterology 2020 20:247
  27. Gastric cancer develops even in Helicobacter pylori(H. pylori)-uninfected patients and its typical histological feature is signet ring cell carcinoma (SRCC) within the mucosal layer. However, the biological chara...

    Authors: Mariko Kiso, Yuji Urabe, Masanori Ito, Kazuhiko Masuda, Tomoyuki Boda, Takahiro Kotachi, Kosaku Hata, Naoki Yorita, Naoko Nagasaki, Madina Abduwali, Yuich Hiyama, Shiro Oka, Shinji Tanaka and Kazuaki Chayama
    Citation: BMC Gastroenterology 2020 20:243
  28. Cystinosis is a multisystemic disease resulting from cystine accumulation primarily in kidney and many other tissues. We intended to study the evolution of less commonly seen extrarenal complications of cystin...

    Authors: Rezan Topaloglu, Ayşe Gültekingil, Bora Gülhan, Fatih Ozaltin, Hülya Demir, Türkmen Çiftci, Numan Demir, Çağrı Mesut Temucin, Aysel Yuce and Okhan Akhan
    Citation: BMC Gastroenterology 2020 20:242

    The Correction to this article has been published in BMC Gastroenterology 2022 22:166

  29. Tumor pyruvate kinase M2 isoform (tM2-PK), which is an isoform of PK-glycolytic enzyme and appears on the surface of cancerous proliferating cells, has been used as a diagnostic biomarker for colorectal cancer...

    Authors: Farideh Rigi, Aliakbar Jannatabad, Azra Izanloo, Reza Roshanravan, Hamid Reza Hashemian and Mohammad Amin Kerachian
    Citation: BMC Gastroenterology 2020 20:241
  30. Leukocytoclastic vasculitis (LCV) is an immune-complex mediated vasculitis characterized by neutrophilic inflammation and nuclear debris in post capillary venules. LCV is a rare dermatologic manifestation of C...

    Authors: Meredith Buck, Igor Dumic, Wendy McDermott, Charles Nordstrom, Samarth Dawan, Andrew Virata, Scott Martin, Ann Hudson, Tamara Milovanovic and Terri Nordin
    Citation: BMC Gastroenterology 2020 20:240
  31. Pigmented bile salts darken the small-bowel lumen and are present with bile acid, which is involved in the development of bowel habits. The small-bowel water content (SBWC) in the ileum could represent the col...

    Authors: Taiki Aoyama, Akira Fukumoto, Kenjiro Shigita, Naoki Asayama, Shinichi Mukai and Shinji Nagata
    Citation: BMC Gastroenterology 2020 20:237
  32. The induction of chronic inflammation, perforation, and abscess by foreign bodies (FBs) in adults is uncommon. We present a delayed diagnosis case for a patient who had a fishbone stuck in the duodenal bulb, r...

    Authors: Zhihui Wang, Zhiqiang Du, Xiangrong Zhou, Tianming Chen and Chunyan Li
    Citation: BMC Gastroenterology 2020 20:236
  33. NETest, a novel multi-gene liquid biopsy has utility in neuroendocrine tumor (NET) diagnosis and identification of residual disease. We independently assessed utility of the NETest to diagnose gastric neuroend...

    Authors: A. Malczewska, A. Procner, A. Walter, K. Kusnierz, W. Zajecki, H. Aslanian and B. Kos-Kudla
    Citation: BMC Gastroenterology 2020 20:235
  34. Melatonin has been shown with anticancer property and therapeutic potential for tumors. However, there lacks a systematic study on the molecular pathways of melatonin and its antitumor effects in gastrointesti...

    Authors: Lu Ao, Li Li, Huaqin Sun, Huxing Chen, Yawei Li, Haiyan Huang, Xianlong Wang, Zheng Guo and Ruixiang Zhou
    Citation: BMC Gastroenterology 2020 20:233
  35. Gastric cancer after Helicobacter pylori (HP) eradication is a crucial clinical challenge today as HP eradication therapy is widely performed. Detecting gastric cancer after HP eradication tends to be difficult w...

    Authors: Akiko Ohno, Jun Miyoshi, Atsushi Kato, Naohiko Miyamoto, Takahito Yatagai, Yu Hada, Mitsunori Kusuhara, Yoko Jimbo, Yosuke Ida, Kengo Tokunaga, Susumu Okamoto and Tadakazu Hisamatsu
    Citation: BMC Gastroenterology 2020 20:232
  36. A recent study by Digby et al. in BMC Gastroenterology evaluated the faecal haemoglobin, age and sex test (FAST) score in the assessment of patients with lower bowel symptoms attended in primary healthcare. Th...

    Authors: Joaquín Cubiella
    Citation: BMC Gastroenterology 2020 20:231

    The original article was published in BMC Gastroenterology 2019 19:213

  37. Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder with increased intestinal iron absorption and therefore iron Overload. iron overload leads to increased levels of toxic non-transferrin b...

    Authors: Jessica Seeßle, Hongying Gan-Schreier, Marietta Kirchner, Wolfgang Stremmel, Walee Chamulitrat and Uta Merle
    Citation: BMC Gastroenterology 2020 20:230
  38. The aim of the study was to compare the onset of oral feeding in the first 24 h after hospital admission with usual oral refeeding and determine whether the timing of the onset of oral feeding influences the r...

    Authors: Edgard Efrén Lozada-Hernández, Omar Barrón-González, Santa Vázquez-Romero, Martin Cano-Rosas and Evelia Apolinar-Jimenez
    Citation: BMC Gastroenterology 2020 20:228
  39. Inpatient status has been shown to be a predictor of poor bowel preparation for colonoscopy; however, the optimal bowel preparation regimen for hospitalized patients is unknown. Our aim was to compare the effi...

    Authors: Patricia V. Hernandez, Jennifer L. Horsley-Silva, Diana L. Snyder, Noemi Baffy, Mary Atia, Laura Koepke, Matthew R. Buras, Elisabeth S. Lim, Kevin Ruff, Sarah B. Umar, Sameer Islam and Francisco C. Ramirez
    Citation: BMC Gastroenterology 2020 20:227
  40. Patients co-infected with hepatitis B virus (HBV) and the human immunodeficiency virus (HIV) are at risk of developing hepatocellular carcinoma (HCC). In sub-Saharan Africa, the overlap between high HIV and HB...

    Authors: Tongai Gibson Maponga, Richard H. Glashoff, Hannali Vermeulen, Barbara Robertson, Sean Burmeister, Marc Bernon, Jones Omoshoro-Jones, Paul Ruff, Alfred I. Neugut, Judith S. Jacobson, Wolfgang Preiser and Monique I. Andersson
    Citation: BMC Gastroenterology 2020 20:226
  41. Studies of microbiota composition of infants with small intestinal ostomy due to various etiologies are limited. Here, we characterized the intestinal microbiota of neonates with ileostomy resulting from disti...

    Authors: Tian Qian, Haitao Zhu, Li Zhu, Chao Chen, Chun Shen and Rong Zhang
    Citation: BMC Gastroenterology 2020 20:224
  42. Intestinal and diffuse gastric adenocarcinomas differ in clinical, epidemiological and molecular features. However, most of the concepts related to the intestinal-type are translated to gastric adenocarcinoma ...

    Authors: Paulo Pimentel Assumpção, Williams Fernandes Barra, Geraldo Ishak, Luiz Gonzaga Vaz Coelho, Felipe José Fernandez Coimbra, Helano Carioca Freitas, Emmanuel Dias-Neto, M. Constanza Camargo and Moyses Szklo
    Citation: BMC Gastroenterology 2020 20:223

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