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  1. Hepatic encephalopathy has a negative impact on health-related quality of life (QoL) in liver cirrhosis. There are scarce and conflicting data on whether type or etiology of liver cirrhosis could be related to...

    Authors: Evangelos Kalaitzakis, Axel Josefsson and Einar Björnsson

    Citation: BMC Gastroenterology 2008 8:46

    Content type: Research article

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  2. Sexual function is impaired in women with inflammatory bowel disease (IBD) as compared to normal controls. We examined disease specific determinants of different aspects of low sexual function.

    Authors: Antje Timmer, Daniela Kemptner, Alexandra Bauer, Angela Takses, Claudia Ott and Alois Fürst

    Citation: BMC Gastroenterology 2008 8:45

    Content type: Research article

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  3. Non alcoholic fatty liver disease (NAFL) consists in the accumulation of fat vacuoles in the cytoplasm of hepatocytes. Many etiologic factors are associated with NAFL, such as, the metabolic syndrome factors, ...

    Authors: Llorenç Caballería, Ma Antonia Auladell, Pere Torán, Guillem Pera, Dolores Miranda, Alba Alumà, José Dario Casas, Laura Muñoz, Carmen Sanchez, Albert Tibau, Marti Birules, Santiago Canut, Jesús Bernad, Josep Aubà, Miren Maite Aizpurua and Enriqueta Alcaraz

    Citation: BMC Gastroenterology 2008 8:44

    Content type: Study protocol

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  4. Epidemiological studies suggest considerable overlap between functional dyspepsia (FD) and irritable bowel syndrome (IBS). To date, no surveys have been performed to investigate the clinical overlap between th...

    Authors: AnJiang WANG, XianHua LIAO, LiShou XIONG, Sui PENG, YingLian XIAO, SiChun LIU, PinJin HU and MinHu CHEN

    Citation: BMC Gastroenterology 2008 8:43

    Content type: Research article

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  5. Mast cells were associated with intestinal ischemia-reperfusion injury, the study was to observe the influence of Ketotifen, Cromolyn Sdium(CS), and Compound 48/80(CP) on the survival rates on the third day af...

    Authors: Hei Zi-qing, Gan Xiao-liang, Huang Pin-jie, Wei Jing, Shen Ning and Gao Wan-ling

    Citation: BMC Gastroenterology 2008 8:42

    Content type: Research article

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  6. The management of coincidental detected gallbladder polyps (GP) is still nebulous. There are few published data regarding their long-term growth. Objective of the present study was to investigate the prevalenc...

    Authors: Wolfgang Kratzer, Mark M Haenle, Andrea Voegtle, Richard A Mason, Atilla S Akinli, Klaus Hirschbuehl, Andreas Schuler and Volker Kaechele

    Citation: BMC Gastroenterology 2008 8:41

    Content type: Research article

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  7. The prevalence of nonalcoholic fatty liver disease (NAFLD) is high. NAFLD is linked to obesity, diabetes mellitus, and hypertriglyceridemia. Approximately 20% of patients with NAFLD will eventually develop cir...

    Authors: Luis Bujanda, Elizabeth Hijona, Mikel Larzabal, Marta Beraza, Pablo Aldazabal, Nerea García-Urkia, Cristina Sarasqueta, Angel Cosme, Belen Irastorza, Alberto González and Juan I Arenas Jr

    Citation: BMC Gastroenterology 2008 8:40

    Content type: Research article

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  8. Patients with advanced cirrhosis of the liver typically display circulatory disturbance. Haemodynamic management may be critical for avoiding and treating functional renal failure in such patients. This study ...

    Authors: Andreas Umgelter, Katrin Wagner, Wolfgang Reindl, Nils Nurtsch, Wolfgang Huber and Roland M Schmid

    Citation: BMC Gastroenterology 2008 8:39

    Content type: Research article

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  9. Motilin, a peptide hormone has a direct excitatory effect on circular smooth muscle strips derived from the human colon. Reduced plasma motilin concentration has been reported in adults with chronic constipati...

    Authors: Narayanan Venkatasubramani, Colin D Rudolph and Manu R Sood

    Citation: BMC Gastroenterology 2008 8:38

    Content type: Research article

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  10. Gastroesophageal reflux disease (GERD) causes a wide range of clinical symptoms and potentially serious complications, but epidemiological data about GERD in China are limited. The aim of this pilot study was ...

    Authors: Yang Cao, Xiaoyan Yan, Xiu-Qiang Ma, Rui Wang, Saga Johansson, Mari-Ann Wallander and Jia He

    Citation: BMC Gastroenterology 2008 8:37

    Content type: Research article

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  11. Protozoan infections are the most serious among all the superimposed infections in HIV patients and claim a number of lives every year. The line of treatment being different for diverse parasites necessitates ...

    Authors: Lekha Tuli, Anil K Gulati, Shyam Sundar and Tribhuban M Mohapatra

    Citation: BMC Gastroenterology 2008 8:36

    Content type: Research article

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  12. Helicobacter pylori is a common pathogen, and its prevalence varies with socioeconomic conditions (10–80%). It has recently been recognized as a class I carcinogen in relation to gastric cancer. The aim of this ...

    Authors: Aliye Soylu, Selvinaz Ozkara, Halil Alıs, Kemal Dolay, Mustafa Kalaycı, Nurgul Yasar and A Baki Kumbasar

    Citation: BMC Gastroenterology 2008 8:35

    Content type: Research article

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  13. The cause and pathophysiology of ulcerative colitis are both mainly unknown. We have previously used whole-genome microarray technique on biopsies obtained from patients with ulcerative colitis to identifiy 5 ...

    Authors: Anders Eriksson, Carl-Fredrik Flach, Anders Lindgren, Eva Kvifors and Stefan Lange

    Citation: BMC Gastroenterology 2008 8:34

    Content type: Research article

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  14. The membrane transporters such as P-glycoprotein (Pgp), the MDR1 gene product, are one of causes of treatment failure in cancer patients. In this study, the epigenetic mechanisms involved in differential MDR1 mRN...

    Authors: Tae-Bum Lee, Jung-Hee Park, Young-Don Min, Kyung-Jong Kim and Cheol-Hee Choi

    Citation: BMC Gastroenterology 2008 8:33

    Content type: Research article

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  15. Invasive pulmonary aspergillosis (IPA) is a rapid, progressive, fatal disease that occurs mostly in immunocompromised patients. Patients with severe liver disease are at a heightened risk for infections. Littl...

    Authors: Dan Li, Liang Chen, Xian Ding, Ran Tao, Yong Xin Zhang and Jie Fei Wang

    Citation: BMC Gastroenterology 2008 8:32

    Content type: Research article

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  16. The ingestion of caustic substances induces an extensive spectrum of injuries to the aerodigestive tract which include extensive necrosis and perforation of the esophagus and stomach. The gold standard of safe...

    Authors: Hao-Tsai Cheng, Chi-Liang Cheng, Cheng-Hui Lin, Jui-Hsiang Tang, Yin-Yi Chu, Nai-Jen Liu and Pang-Chi Chen

    Citation: BMC Gastroenterology 2008 8:31

    Content type: Research article

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  17. Irritable Bowel Syndrome (IBS) is a chronic/common condition that causes a significant effect on the individual (reduced quality of life), society (time lost off work) and health services. Comparison of studie...

    Authors: Andrea K Roalfe, Lesley M Roberts and Sue Wilson

    Citation: BMC Gastroenterology 2008 8:30

    Content type: Research article

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  18. In Wilson disease, copper is not sufficiently excreted into bile due to the absence or malfunction of the Wilson protein copper ATPase in the excretory pathway of hepatocytes. Copper is found in sweat. It is u...

    Authors: Mark Schaefer, Mavi Schellenberg, Uta Merle, Karl Heinz Weiss and Wolfgang Stremmel

    Citation: BMC Gastroenterology 2008 8:29

    Content type: Research article

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  19. Normal upper endoscopy may be a marker of ischemic heart disease in patients with unexplained chest/epigastric pain.

    Authors: Estrid Muff Munk, Bente Nørgård, Claus Dethlefsen, Hans Gregersen, Asbjørn Mohr Drewes, Peter Funch-Jensen and Henrik Toft Sørensen

    Citation: BMC Gastroenterology 2008 8:28

    Content type: Research article

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  20. Genetic factors as well as environmental factors are important in the development of NAFLD and in this study we investigated associations between polymorphisms of peroxisome proliferators-activated receptor γ ...

    Authors: Masato Yoneda, Kikuko Hotta, Yuichi Nozaki, Hiroki Endo, Takashi Uchiyama, Hironori Mawatari, Hiroshi Iida, Shingo Kato, Kunihiro Hosono, Koji Fujita, Kyoko Yoneda, Hirokazu Takahashi, Hiroyuki Kirikoshi, Noritoshi Kobayashi, Masahiko Inamori, Yasunobu Abe…

    Citation: BMC Gastroenterology 2008 8:27

    Content type: Research article

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  21. Pouchitis is the most common long-term complication of in patients with restorative proctocolectomy and ileal pouch-anal anastomosis. Patients often develop antibiotic-dependent form of pouchitis requiring lon...

    Authors: Bo Shen, Feza H Remzi, A Rocio Lopez and Elaine Queener

    Citation: BMC Gastroenterology 2008 8:26

    Content type: Research article

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  22. Consensus on how to adequately measure patient satisfaction with health care is limited, and has led to the development of many questionnaires with various methodological problems. The objective of this study ...

    Authors: Jolie J Gutteling, Robert A de Man, Jan JV Busschbach and Anne-Sophie E Darlington

    Citation: BMC Gastroenterology 2008 8:25

    Content type: Research article

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  23. Alterations in gene splicing occur in human sporadic colorectal cancer (CRC) and may contribute to tumour progression. The K-ras proto-oncogene encodes two splice variants, K-ras 4A and 4B, and K-ras activating m...

    Authors: Charles E Patek, Mark J Arends, Lorraine Rose, Feijun Luo, Marion Walker, Paul S Devenney, Rachel L Berry, Nicola J Lawrence, Rachel A Ridgway, Owen J Sansom and Martin L Hooper

    Citation: BMC Gastroenterology 2008 8:24

    Content type: Research article

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  24. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently backs up (or refluxes) into the gullet (or esophagus), and it has serious consequences for the quality of life. Usually this is felt a...

    Authors: Anke JE de Veer, Judith T Bos, Riet C Niezen-de Boer, Clarisse JM Böhmer and Anneke L Francke

    Citation: BMC Gastroenterology 2008 8:23

    Content type: Research article

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  25. Little is known about how to most effectively deliver relevant information to patients scheduled for endoscopy.

    Authors: Christian Felley, Thomas V Perneger, Isabelle Goulet, Catherine Rouillard, Nadereh Azar-Pey, Gian Dorta, Antoine Hadengue and Jean-Louis Frossard

    Citation: BMC Gastroenterology 2008 8:22

    Content type: Research article

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  26. The pathophysiological basis of diabetic gastroparesis is poorly understood, in large part due to the almost complete lack of data on neuropathological and molecular changes in the stomachs of patients. Experi...

    Authors: Pankaj J Pasricha, Nonko D Pehlivanov, Guillermo Gomez, Harsha Vittal, Matthew S Lurken and Gianrico Farrugia

    Citation: BMC Gastroenterology 2008 8:21

    Content type: Research article

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  27. The Brazilian consensus recommends a short-term treatment course with clarithromycin, amoxicillin and proton-pump inhibitor for the eradication of Helicobacter pylori (H. pylori). This treatment course has good e...

    Authors: Fernando M Silva, Jaime N Eisig, Ana Cristina S Teixeira, Ricardo C Barbuti, Tomás Navarro-Rodriguez and Rejane Mattar

    Citation: BMC Gastroenterology 2008 8:20

    Content type: Research article

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  28. Acute pancreatitis is an inflammatory disease characterized by local tissue injury and systemic inflammatory response leading to massive nitric oxide (NO) production and haemodynamic disturbances. Therefore, t...

    Authors: Enilton A Camargo, Maria Andréia Delbin, Tatiane Ferreira, Elen CT Landucci, Edson Antunes and Angelina Zanesco

    Citation: BMC Gastroenterology 2008 8:19

    Content type: Research article

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  29. The relationship between proton pump inhibitor therapy and other acid suppressing medications and the risk of gastrointestinal infections remains controversial.

    Authors: C Mel Wilcox, Toni Martin, Milind Phadnis, Jean Mohnen, Julie Worthington and Basil I Hirschowitz

    Citation: BMC Gastroenterology 2008 8:18

    Content type: Research article

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  30. Our previous proteomic study showed that the senescence marker protein (SMP30) is selectively present in the plasma of a murine model of acute liver failure (ALF). The aim of this study was to validate this SM...

    Authors: Sa Lv, Jiang-hua Wang, Feng Liu, Yan Gao, Ran Fei, Shao-cai Du and Lai Wei

    Citation: BMC Gastroenterology 2008 8:17

    Content type: Research article

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  31. Liver diseases are suspected risk factors for intracerebral haemorrhage (ICH). We conducted a population-based case-control study to examine risk of ICH among hospitalised patients with liver cirrhosis and oth...

    Authors: Henning Grønbæk, Søren P Johnsen, Peter Jepsen, Mette Gislum, Hendrik Vilstrup, Ulrik Tage-Jensen and Henrik T Sørensen

    Citation: BMC Gastroenterology 2008 8:16

    Content type: Research article

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  32. A Stanford University study reported that in asymptomatic GERD patients who were being treated with a proton pump inhibitor (PPI), 50% had pathologic esophageal acid exposure.

    Authors: Lauren B Gerson, George Triadafilopoulos, Peyman Sahbaie, Winston Young, Sheldon Sloan, Malcolm Robinson, Philip B Miner Jr and Jerry D Gardner

    Citation: BMC Gastroenterology 2008 8:15

    Content type: Correspondence

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  33. Cell death mode has been studied in cancer, autoimmune, and neurodegenerative diseases. In this study, apoptosis and necrosis are investigated for the first time in patients with chronic calculous cholecystitis.

    Authors: Constantinos Simopoulos, Alexandra K Tsaroucha, Byron Asimakopoulos, Alexandra Giatromanolaki, Paschalis Gavriilidis, Alexandros Polychronidis and Anastasios Karayiannakis

    Citation: BMC Gastroenterology 2008 8:14

    Content type: Research article

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  34. We address the independent and interactive roles of habitual betel quid chewing and other known risk factors for biochemical dysfunction and cirrhosis of the liver.

    Authors: Ching-Feng Lin, Tun-Jen Shiau, Ying-Chin Ko, Ping-Ho Chen and Jung-Der Wang

    Citation: BMC Gastroenterology 2008 8:13

    Content type: Research article

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  35. The precise role of capsule endoscopy in the diagnostic algorithm of obscure gastrointestinal bleeding has yet to be determined. Despite the higher diagnostic yield of capsule endoscopy, the actual impact on c...

    Authors: Hiroki Endo, Nobuyuki Matsuhashi, Masahiko Inamori, Keiko Akimoto, Tomohiko Ohya, Tatsuro Yanagawa, Masako Asayama, Kantaro Hisatomi, Takuma Teratani, Koji Fujita, Masato Yoneda and Atsushi Nakajima

    Citation: BMC Gastroenterology 2008 8:12

    Content type: Research article

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  36. The use of thickeners is a standard therapy for decreasing episodes of regurgitation or vomiting in infants. However, it remains to be investigated whether thickener is effective for vomiting and/or chronic re...

    Authors: Reiko Miyazawa, Takeshi Tomomasa, Hiroaki Kaneko, Hirokazu Arakawa, Nobuzo Shimizu and Akihiro Morikawa

    Citation: BMC Gastroenterology 2008 8:11

    Content type: Research article

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  37. In a cross-sectional community based study, as part of a randomised controlled trial of eradication of Helicobacter pylori infection, the association between blood pressure and symptoms of gastro-oesophageal r...

    Authors: Liam J Murray, Peter McCarron, Roger B McCorry, Lesley A Anderson, Athene J Lane, Brian T Johnston, George Davey Smith and Richard F Harvey

    Citation: BMC Gastroenterology 2008 8:10

    Content type: Research article

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  38. Human gastrointestinal mucosa regenerates vigorously throughout life, but the factors controlling cell fate in mature mucosa are poorly understood. GATA transcription factors direct cell proliferation and diff...

    Authors: Hanna Haveri, Mia Westerholm-Ormio, Katri Lindfors, Markku Mäki, Erkki Savilahti, Leif C Andersson and Markku Heikinheimo

    Citation: BMC Gastroenterology 2008 8:9

    Content type: Research article

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  39. Bowel symptoms are considered indicators of the presence of colorectal cancer and other bowel diseases. Self administered questionnaires that elicit information about lower bowel symptoms have not been assesse...

    Authors: Barbara-Ann Adelstein, Les Irwig, Petra Macaskill, Peter H Katelaris, David B Jones and Les Bokey

    Citation: BMC Gastroenterology 2008 8:8

    Content type: Research article

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  40. Acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography and benefit of pharmacological treatment is unclear. Although prophylactic use of corticosteroid for reduction of p...

    Authors: Minghua Zheng, Jianling Bai, Bosi Yuan, Feng Lin, Jie You, Mingqin Lu, Yuewen Gong and Yongping Chen

    Citation: BMC Gastroenterology 2008 8:6

    Content type: Research article

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  41. Therapeutic biliary procedures disrupt the function of the sphincter of Oddi. Patients are potential "bile refluxers". The aim of this study was to assess how these procedures affect the histology-based bile r...

    Authors: Sedef Kuran, Erkan Parlak, Gulden Aydog, Sabite Kacar, Nurgul Sasmaz, Ali Ozden and Burhan Sahin

    Citation: BMC Gastroenterology 2008 8:4

    Content type: Research article

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  42. Denmark has one of the highest alcohol consumption rates in Northern Europe. The overall per capita alcohol consumption has been stable in recent decades, but surveys have indicated that consumption has decrea...

    Authors: Peter Jepsen, Hendrik Vilstrup and Henrik T Sørensen

    Citation: BMC Gastroenterology 2008 8:3

    Content type: Research article

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  43. In rats, esophagogastroduodenal anastomosis (EGDA) without concomitant chemical carcinogen treatment leads to gastroesophageal reflux disease, multilayered epithelium (MLE, a presumed precursor in intestinal m...

    Authors: Xiaoxin Chen, Rong Qin, Ba Liu, Yan Ma, Yinghao Su, Chung S Yang, Jonathan N Glickman, Robert D Odze and Nicholas J Shaheen

    Citation: BMC Gastroenterology 2008 8:1

    Content type: Research article

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  44. Previous studies on healthy people show that vinegar delays gastric emptying and lowers postprandial blood glucose and insulin levels. The aim of this study was to investigate the effect of apple cider vinegar...

    Authors: Joanna Hlebowicz, Gassan Darwiche, Ola Björgell and Lars-Olof Almér

    Citation: BMC Gastroenterology 2007 7:46

    Content type: Research article

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  45. To compare tumor necrosis in hepatoma induced in rats by a single percutaneous injection of ethanol (PEI) or acetic acid (PAI).

    Authors: Enrico M Zardi, Domenico Borzomati, Fabio Cacciapaglia, Antonio Picardi, Sergio Valeri, Antonella Bianchi, Tommaso Galeotti, Giusy Coppolino, Roberto Coppola and Antonella Afeltra

    Citation: BMC Gastroenterology 2007 7:45

    Content type: Research article

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  46. Peroxisome proliferators-activated receptor alpha (PPARα) activation modulates cholesterol metabolism and suppresses bile acid synthesis. This study aims to evaluate the effect of short-term administration of ...

    Authors: Mehmet Cindoruk, Mustafa Kerem, Tarkan Karakan, Bulent Salman, Okan Akin, Murat Alper, Ozlem Erdem and Selahattin Ünal

    Citation: BMC Gastroenterology 2007 7:44

    Content type: Research article

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  47. Patients with malignant tumours of the upper gastrointestinal tract tumours exhibit important alarm symptoms such as dysphagia that warrant clinical investigations. An endoscopic examination of the upper gastr...

    Authors: Nafees A Qureshi, Michael T Hallissey and John W Fielding

    Citation: BMC Gastroenterology 2007 7:43

    Content type: Research article

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