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  1. The prevalence of fatty liver disease is potentially increasing in adolescents and young adults (AYAs) due to the obesity and alcohol pandemics. The aim of this study was to assess the prevalence of alcohol-as...

    Authors: Naim Alkhouri, Ashraf Almomani, Phuc Le, Julia Y. Payne, Imad Asaad, Celine Sakkal, Miriam Vos, Mazen Noureddin and Prabhat Kumar
    Citation: BMC Gastroenterology 2022 22:366
  2. Methotrexate is an immunomodulatory drug for patients with Crohn’s disease. Erythrocyte MTX-polyglutamates (MTX-PG1-5) may be used for therapeutic drug monitoring (TDM) as MTX-PG is thought to mediate MTX’s effic...

    Authors: M. M. van de Meeberg, M. L. Seinen, H. H. Fidder, M. Lin, B. Oldenburg, N. K. de Boer, G. Bouma, R. de Jonge and M. Bulatović Ćalasan
    Citation: BMC Gastroenterology 2022 22:365
  3. Targeted puncture of an appropriate portal venous branch during transjugular intrahepatic portosystemic shunt (TIPS) procedure may reduce the risk of postprocedural overt hepatic encephalopathy (HE). This stud...

    Authors: Chongtu Yang, Yang Chen, Chaoyang Wang, Jiacheng Liu, Songjiang Huang, Chen Zhou, Yingliang Wang, Shuguang Ju, Tongqiang Li, Yaowei Bai, Wei Yao and Bin Xiong
    Citation: BMC Gastroenterology 2022 22:363
  4. Gastric carcinosarcoma is most frequently diagnosed at an advanced stage when the tumor is generally large with invasion into other organs, lymph node metastasis, and distant metastasis. Standard chemotherapy ...

    Authors: Hirokatsu Hayashi, Akitaka Makiyama, Naoki Okumura, Itaru Yasufuku, Chiemi Saigo, Tamotsu Takeuchi, Tatsuhiko Miyazaki, Yoshihiro Tanaka, Nobuhisa Matsuhashi, Katsutoshi Murase, Takao Takahashi, Manabu Futamura and Kazuhiro Yoshida
    Citation: BMC Gastroenterology 2022 22:360
  5. Gastric cancer ranks high in terms of morbidity and mortality worldwide. Multimodal therapy is therefore essential for locally advanced gastric cancer. Recent studies have demonstrated that both perioperative ...

    Authors: Jinming Shi, Ning Li, Yuan Tang, Liming Jiang, Lin Yang, Shulian Wang, Yongwen Song, Yueping Liu, Hui Fang, Ningning Lu, Shunan Qi, Bo Chen, Ziyu Li, Shixin Liu, Jun Wang, Wenling Wang…
    Citation: BMC Gastroenterology 2022 22:359
  6. Recent studies have shown that chronic kidney disease (CKD) prevalence is significantly higher in patients with hepatic steatosis (HS); however, it remains unclear whether HS is associated with serum creatinin...

    Authors: Juan Ma, Zhongcao Wei, Qian Wang, Xiaolan Lu, Zhihua Zhou, Ruohan Li, Qiuai Shu, Yixin Liu, Jinhai Wang, Na Liu and Haitao Shi
    Citation: BMC Gastroenterology 2022 22:358
  7. Situs inversus totalis (SIT) is a rare congenital anomaly characterized by a complete transposition of all the viscera. SIT cases were usually reported because of the presence of tumors, leading to false assoc...

    Authors: Cheng Zhang, Bo Zhang, Haifeng Huang, Qida Hu, Yibing Jin, Qingsong Yu, Junsen Wang, Xin Zhang and Yun Zhang
    Citation: BMC Gastroenterology 2022 22:357
  8. Authors: Michael V. Chiorean, Jessica R. Allegretti, Puza P. Sharma, Benjamin Chastek, Leonardo Salese, Elizabeth J. Bell, Jesse Peterson-Brandt, Joseph C. Cappelleri, Xiang Guo and Nabeel Khan
    Citation: BMC Gastroenterology 2022 22:356

    The original article was published in BMC Gastroenterology 2022 22:177

  9. We retrospectively compared the effect of endoscopic variceal obturation (EVO) and retrograde transvenous obliteration (RTO) in acute cardiofundal variceal bleeding.

    Authors: Han Ah Lee, Jungwon Kwak, Sung Bum Cho, Young-Sun Lee, Young Kul Jung, Ji Hoon Kim, Seung Up Kim, Hyonggin An, Hyung Joon Yim, Jong Eun Yeon and Yeon Seok Seo
    Citation: BMC Gastroenterology 2022 22:355
  10. To evaluate the usefulness of Contrast-enhanced ultrasound (CEUS) in the diagnosis and differential diagnosis of Polypoid lesions of gallbladder (PLGs) ≥ 1 cm.

    Authors: Xiaoyue Zhang, Shaoshan Tang, Liping Huang, Hong Jin, Yijiao Wang, Yao Wang, Zhan Liu and Chunyu Lu
    Citation: BMC Gastroenterology 2022 22:354
  11. Upper gastrointestinal bleeding (UGIB) is a common complication in renal transplant recipients. However, the risk stratification value of bleeding scoring systems in these patients is unclear, and data regardi...

    Authors: Rui Wang and Qiang Wang
    Citation: BMC Gastroenterology 2022 22:353
  12. Chronic atrophic gastritis (CAG) is a precancerous disease that often leads to the development of gastric cancer (GC) and is positively correlated with GC morbidity. However, the sensitivity of the endoscopic ...

    Authors: Quchuan Zhao, Qing Jia and Tianyu Chi
    Citation: BMC Gastroenterology 2022 22:352
  13. Liver cancer is a severe public health problem worldwide, and it creates a relatively higher disease burden in China than in the Western world. Despite achieving notable progress in China, potential difference...

    Authors: Qiaoxin Wei, Haiyang Zhou, Xinhui Hou, Xiaoping Liu, Sisi Chen, Xueying Huang, Yu Chen, Mei Liu and Zhongping Duan
    Citation: BMC Gastroenterology 2022 22:351
  14. To identify patients suitable for endoscopic injection sclerotherapy (EIS) by evaluating their portal hemodynamics and liver function.

    Authors: Ryuta Shigefuku, Hideaki Takahashi, Tsunamasa Watanabe, Nobuhiro Hattori, Hiroki Ikeda, Kotaro Matsunaga, Takuya Ehira, Tatsuya Suzuki, Nobuyuki Matsumoto, Chiaki Okuse, Motoh Iwasa, Hayato Nakagawa, Fumio Itoh and Michihiro Suzuki
    Citation: BMC Gastroenterology 2022 22:350
  15. To investigate the effects of a reversed segment of the distal small intestine to improve weight gain in an experimental short bowel syndrome (SBS) model in piglets.

    Authors: Lasse Hartmann Schmidt, Jesper Stensig Aa, Bolette Hartmann, Gunvor Iben Madsen, Niels Qvist and Mark Bremholm Ellebæk
    Citation: BMC Gastroenterology 2022 22:349
  16. Hepatocellular carcinoma (HCC) is a kind of tumor with high invasiveness, and patients with advanced HCC have a higher risk of early death. The aim of the present study was to identify the risk factors of earl...

    Authors: Haidong Zhang, Xuanlong Du, Hui Dong, Wenjing Xu, Pengcheng Zhou, Shiwei Liu, Xin Qing, Yu Zhang, Meng Yang and Yewei Zhang
    Citation: BMC Gastroenterology 2022 22:348
  17. Primary gastric lymphoma (PGL) is the most common extranodal non-Hodgkin lymphoma (NHL). Due to the rarity of the disease, it is important to create a predictive model that provides treatment and prognosis for...

    Authors: Jinru Yang, Tao Liu, Ying Zhu, Fangyuan Zhang, Menglan Zhai, Dejun Zhang, Lei Zhao, Min Jin, Zhenyu Lin, Tao Zhang, Liling Zhang and Dandan Yu
    Citation: BMC Gastroenterology 2022 22:347
  18. Adenosquamous carcinoma (ASC)with concurrent gastric carcinoma with lymphoid stroma (GCLS) are extremely rare tumors. There are only limited cases reported in the literature. Epstein–Barr virus (EBV) infection...

    Authors: Fang Cao, Yan Yan, Dongfeng Niu, Xiaozheng Huang, Ling Jia, Xinting Diao and Zhongwu Li
    Citation: BMC Gastroenterology 2022 22:346
  19. Esophageal cancer (EC), one highly malignant gastrointestinal cancer, is the 6th leading cause of cancer-related deaths worldwide. Necroptosis and long non-coding RNA (lncRNA) play important roles in the occur...

    Authors: Yang Liu, Hongyu Hao, Lin Kang, Guona Zheng, Xiaowan Guo, Bingjie Li, Huanfen Zhao and Han Hao
    Citation: BMC Gastroenterology 2022 22:345
  20. Esophageal carcinoma (ESCA) is a common malignancy with a poor prognosis. Previous research has suggested that necroptosis is involved in anti-tumor immunity and promotes oncogenesis and cancer metastasis, whi...

    Authors: Kai Sun, Juan-juan Hong, Dong-mei Chen, Zhan-xiong Luo and Jing-zhang Li
    Citation: BMC Gastroenterology 2022 22:344
  21. Fecal microbiota transplantation (FMT) is a potential treatment for irritable bowel syndrome (IBS), but its efficacy in Japanese IBS patients is unknown. This study aimed to evaluate the efficacy, side effects...

    Authors: Motonobu Hamazaki, Tsunaki Sawada, Takeshi Yamamura, Keiko Maeda, Yasuyuki Mizutani, Eri Ishikawa, Satoshi Furune, Kenta Yamamoto, Takuya Ishikawa, Naomi Kakushima, Kazuhiro Furukawa, Eizaburo Ohno, Takashi Honda, Hiroki Kawashima, Masatoshi Ishigami, Masanao Nakamura…
    Citation: BMC Gastroenterology 2022 22:342
  22. Clinical evidence of the preventive effectiveness of medium-class topical corticosteroids for capecitabine-induced hand foot syndrome (HFS) is limited. Although the pathogenesis and mechanism of HFS are unclea...

    Authors: Yohei Iimura, Naoki Furukawa, Masaaki Ishibashi, Yuka Ahiko, Taro Tanabe, Susumu Aikou, Dai Shida, Masanori Nojima, Seiichiro Kuroda and Narikazu Boku
    Citation: BMC Gastroenterology 2022 22:341
  23. Optimal management of cirrhosis is complex, and patients often lack knowledge and skills, which can affect self-management. We assessed patient knowledge about cirrhosis and examined whether knowledge was asso...

    Authors: Patricia C. Valery, Christina M. Bernardes, Kelly L. Hayward, Gunter Hartel, Katelin Haynes, Louisa G. Gordon, Katherine A. Stuart, Penny L. Wright, Amy Johnson and Elizabeth E. Powell
    Citation: BMC Gastroenterology 2022 22:340
  24. First Nations Peoples of Australia are disproportionally affected by hepatitis C (HCV) infection. Through a prospective study we evaluated the outcome of direct-acting antiviral (DAA) therapy among First Natio...

    Authors: Paul J. Clark, Patricia C. Valery, James Ward, Simone I. Strasser, Martin Weltman, Alexander Thompson, Miriam T. Levy, Barbara Leggett, Amany Zekry, Julian Rong, Peter Angus, Jacob George, Steven Bollipo, Bruce McGarity, William Sievert, Gerry Macquillan…
    Citation: BMC Gastroenterology 2022 22:339
  25. A missed diagnosis of colorectal polyps during colonoscopy may be associated with the occurrence of interval colorectal cancer. The risk factors for a missed diagnosis or a method to predict the risk of a miss...

    Authors: Xiaobo Wang, Haiyang Guo, Yong Tang, Lin Chen and Xianfei Wang
    Citation: BMC Gastroenterology 2022 22:338
  26. Gastrointestinal bleeding is one of the major gastrointestinal diseases. In this study, our objective was to compare Glasgow-Blatchford score (GBS), AIMS65 score, MAP score, Modified GBS, and Iino score as out...

    Authors: Yoshihiro Sasaki, Tomoko Abe, Norio Kawamura, Taisei Keitoku, Isamu Shibata, Shino Ohno, Keiichi Ono and Makoto Makishima
    Citation: BMC Gastroenterology 2022 22:337
  27. Incidentalomas, defined as incidental findings on imaging, are a growing concern. Our aim was to determine the impact and outcomes of extrahepatic incidentalomas on liver transplantation.

    Authors: Pedro Cortés, Hassan M. Ghoz, Fernando Stancampiano, Mohamed Omer, Balkishan Malviya, Andrew W. Bowman and William C. Palmer
    Citation: BMC Gastroenterology 2022 22:336
  28. Nonalcoholic steatohepatitis (NASH), the inflammatory subtype of nonalcoholic fatty liver disease, is underdiagnosed and expected to become the leading indication for liver transplant in the United States. We ...

    Authors: Mary Rinella, Donna R. Cryer, Amy Articolo, Travis Fisher, Jennifer Schneider and Karl Nadolsky
    Citation: BMC Gastroenterology 2022 22:335
  29. Standard treatment strategy for low rectal cancer in Japan is different from Western countries. Total mesorectum excision (TME) + lateral lymph node dissection (LLND) is mainly carried out in Japan, whereas ne...

    Authors: Hiroshi Miyakita, Lin Fung Chan, Kazutake Okada, Hajime Kayano, Masaki Mori, Sotaro Sadahiro and Seiichiro Yamamoto
    Citation: BMC Gastroenterology 2022 22:334
  30. Nasointestinal tubes (NITs) have been increasingly used in patients with small bowel obstruction (SBO); However, severe adverse events (SAEs) of NITs might threaten the lives of patients. The indications of NI...

    Authors: Hui Wang, Jun-rong Zhang, Shuai Chen, Ping Hou, Qing-feng Chen, Zong-qi Weng, Xin-chang Shang-guan, Bing-qiang Lin and Xian-qiang Chen
    Citation: BMC Gastroenterology 2022 22:332
  31. Hepatic arterial variations were fully elaborated in anatomical monographs. Here, we aimed to present a rare case with multiple arterial variations of the liver complicated laparoscopic pancreaticoduodenectomy.

    Authors: Yong Yan, Bailin Wang, Wei Yuan, Jiansong Zhang, Junhao Xiao and Yanhua Sha
    Citation: BMC Gastroenterology 2022 22:331
  32. Thyroid dysfunction has been reported in severe liver diseases. The aim of this study was to analyze the impact of serum thyroid-stimulation hormone (TSH) levels on the prognosis of patients with hepatitis B v...

    Authors: Jun-feng Chen, Wei-zhen Weng, Miao Huang, Xiao-hua Peng, Jing Zhang, Jing Xiong, Jian-rong He, Shao-quan Zhang, Hui-juan Cao, Bin Gao, Deng-na Lin, Juan Gao, Zhi-liang Gao and Bing-liang Lin
    Citation: BMC Gastroenterology 2022 22:330
  33. The pathological evaluation of tissues with cholangitis is considered difficult, which can often occur after endoscopic sphincterotomy (EST) and endoscopic biliary stenting (EBS). This study aimed to evaluate ...

    Authors: Toshinori Aoki, Eizaburo Ohno, Takuya Ishikawa, Yasuyuki Mizutani, Tadashi Iida, Kentaro Yamao, Takeshi Yamamura, Kazuhiro Furukawa, Masanao Nakamura, Takashi Honda, Masatoshi Ishigami, Hiroshi Yatsuya and Hiroki Kawashima
    Citation: BMC Gastroenterology 2022 22:329
  34. Hepatic arterial infusion chemotherapy delivers the drug directly to the liver. We aim to explore the benefits and tolerability of Hepatic arterial infusion chemotherapy plus regorafenib in advanced colorectal...

    Authors: Guang Cao, Xiaodong Wang, Hui Chen, Song Gao, Jianhai Guo, Peng Liu, Haifeng Xu, Liang Xu, Xu Zhu and Renjie Yang
    Citation: BMC Gastroenterology 2022 22:328
  35. The importance of enteral nutrition (EN) in acute pancreatitis (AP) has been emphasised. Nasogastric (NG) feeding has been the preferred route for EN delivery in most AP patients intolerant to oral intake. How...

    Authors: Jiajia Lin, Cheng Lv, Cuili Wu, He Zhang, Zirui Liu, Lu Ke, Gang Li, Zhihui Tong, Jianfeng Tu and Weiqin Li
    Citation: BMC Gastroenterology 2022 22:327
  36. Transarterial radioembolization (TARE) with yttrium-90 microspheres is a clinically effective therapy for hepatocellular carcinoma (HCC) treatment. This study aimed to perform a systematic review of the availa...

    Authors: J. C. Alonso, I. Casans, F. M. González, D. Fuster, A. Rodríguez, N. Sánchez, I. Oyagüez, R. Burgos, A. O. Williams and N. Espinoza
    Citation: BMC Gastroenterology 2022 22:326
  37. Bile acid diarrhoea (BAD) can be severely debilitating and negatively affect patients’ quality of life (QoL). We carried out a multi-centre prospective study exploring QoL outcomes in patients with BAD after t...

    Authors: Aditi Kumar, Niall Galbraith, Hafid O. Al-Hassi, Manushri Jain, Oliver Phipps, Jeffrey Butterworth, Helen Steed, John McLaughlin and Matthew J. Brookes
    Citation: BMC Gastroenterology 2022 22:325
  38. Non-alcoholic fatty liver disease (NAFLD) is the commonest liver condition in the western world and is directly linked to obesity and the metabolic syndrome. Elevated body mass index is regarded as a major ris...

    Authors: Kushala W. M. Abeysekera, James G. Orr, Fiona H. Gordon, Laura D. Howe, Julian Hamilton-Shield, Jon Heron and Matthew Hickman
    Citation: BMC Gastroenterology 2022 22:323
  39. Despite an effective vaccine, hepatitis B remains a major global health problem due to its significant morbidity and mortality. Vaccination in immunosuppressed patients such as those treated for an inflammator...

    Authors: Juliette Besombes, Faouzi Souala, Guillaume Bouguen, Dominique Guyader, Claire Grolhier, Vincent Thibault and Charlotte Pronier
    Citation: BMC Gastroenterology 2022 22:322
  40. To compare the efficacy and safety of transcatheter arterial chemoembolization combined with microwave ablation (TACE–MWA) versus TACE alone for the treatment of recurrent small hepatocellular carcinoma (sHCC)...

    Authors: Jie Ji, Wei Yang, Hai-Bin Shi, Sheng Liu and Wei-Zhong Zhou
    Citation: BMC Gastroenterology 2022 22:321
  41. Most microbiota studies in microscopic colitis patients are performed after diagnostic colonoscopy without considering the potential effect of colonic lavage. Patients may achieve clinical remission after colo...

    Authors: Lissette Batista, Virginia Robles, Chaysavanh Manichanh, Laura Ruiz, Danila Guagnozzi, Ferran Pinsach, Francisco Guarner and Fernando Fernández-Bañares
    Citation: BMC Gastroenterology 2022 22:320
  42. To date, no in-depth studies have focused on the impact of various clinical characteristics of esophageal squamous cell carcinoma (ESCC), including its association with subjective symptoms, on patient prognosi...

    Authors: Jun Nakamura, Noriaki Manabe, Tomoki Yamatsuji, Yoshinori Fujiwara, Takahisa Murao, Maki Ayaki, Minoru Fujita, Akiko Shiotani, Tomio Ueno, Yasumasa Monobe, Takashi Akiyama, Ken Haruma, Yoshio Naomoto and Jiro Hata
    Citation: BMC Gastroenterology 2022 22:319
  43. The purpose of this retrospective study aimed to assess the accuracy of detection of remnant common bile duct (CBD) stones by injecting saline through endoscopic nasobiliary drainage (ENBD) tubes under transab...

    Authors: XiaoDong Wu, ShuoDong Wu and ShaoShan Tang
    Citation: BMC Gastroenterology 2022 22:318
  44. Allied disorders of Hirschsprung’s disease (ADHD) mainly present with bowel obstruction, intestinal dilatation, and chronic constipation, while recurrent spontaneous pneumoperitoneum was rarely reported. We ai...

    Authors: Yue Yin, Yun Zhang, Bei Tan, Weixun Zhou, Wei Liu and Xuejun Zeng
    Citation: BMC Gastroenterology 2022 22:316

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