Park SH: Current status of liver disease in Korea: Nonalcoholic fatty liver disease. Korean J Hepatol. 2009, 15: S34-10.3350/kjhep.2009.15.S6.S34.
Article
PubMed
Google Scholar
Angulo P: Nonalcoholic Fatty Liver Disease. N Engl J Med. 2002, 346: 1221-1231. 10.1056/NEJMra011775.
Article
CAS
PubMed
Google Scholar
Chitturi S, Wong VW-S, Farrell G: Nonalcoholic fatty liver in Asia: Firmly entrenched and rapidly gaining ground. J Gastroenterol Hepatol. 2011, 26: 163-172.
Article
PubMed
Google Scholar
Moscatiello S, Manini R, Marchesini G: Diabetes and liver disease: an ominous association. Nutr Metab Cardiovasc Dis. 2007, 17: 63-70. 10.1016/j.numecd.2006.08.004.
Article
PubMed
Google Scholar
Lonardo A, Lombardini S, Ricchi M, Scaglioni F, Loria P: Review article: hepatic steatosis and insulin resistance. Aliment Pharmacol Ther. 2005, 22 (Suppl 2): 64-70.
Article
CAS
PubMed
Google Scholar
Bedogni G, Gastaldelli A, Manco M, De Col A, Agosti F, Tiribelli C, Sartorio A: Relationship between fatty liver and glucose metabolism: a cross-sectional study in 571 obese children. Nutr Metab Cardiovasc Dis. 2010, 22: 120-126.
Article
PubMed
Google Scholar
Lin YC, Lo HM, Chen JD: Sonographic fatty liver, overweight and ischemic heart disease. World J Gastroenterol. 2005, 11: 4838-4842.
Article
PubMed
PubMed Central
Google Scholar
Hamaguchi M, Kojima T, Takeda N, Nagata C, Takeda J, Sarui H, Kawahito Y, Yoshida N, Suetsugu A, Kato T, et al: Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. World J Gastroenterol. 2007, 13: 1579-1584.
Article
CAS
PubMed
PubMed Central
Google Scholar
Volzke H, Robinson DM, Kleine V, Deutscher R, Hoffmann W, Ludemann J, Schminke U, Kessler C, John U: Hepatic steatosis is associated with an increased risk of carotid atherosclerosis. World J Gastroenterol. 2005, 11: 1848-1853.
Article
PubMed
PubMed Central
Google Scholar
Targher G, Bertolini L, Padovani R, Rodella S, Tessari R, Zenari L, Day C, Arcaro G: Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients. Diabetes Care. 2007, 30: 1212-1218. 10.2337/dc06-2247.
Article
PubMed
Google Scholar
Choi SY, Kim D, Kim HJ, Kang JH, Chung SJ, Park MJ, Kim YS, Kim CH, Choi SH, Kim W, et al: The relation between non-alcoholic fatty liver disease and the risk of coronary heart disease in Koreans. Am J Gastroenterol. 2009, 104: 1953-1960. 10.1038/ajg.2009.238.
Article
PubMed
Google Scholar
Machado M, Cortez-Pinto H: Non-alcoholic steatohepatitis and metabolic syndrome. Curr Opin Clin Nutr Metab Care. 2006, 9: 637-642. 10.1097/01.mco.0000241677.40170.17.
Article
PubMed
Google Scholar
Vanni E, Bugianesi E, Kotronen A, De Minicis S, Yki-Jarvinen H, Svegliati-Baroni G: From the metabolic syndrome to NAFLD or vice versa?. Dig Liver Dis. 2010, 42: 320-330. 10.1016/j.dld.2010.01.016.
Article
CAS
PubMed
Google Scholar
Rhee E-J, Lee W-Y, Cho Y-K, Kim B-I, Sung K-C: Hyperinsulinemia and the Development of Nonalcoholic Fatty Liver Disease in Nondiabetic Adults. Am J Med. 2011, 124: 69-76. 10.1016/j.amjmed.2010.08.012.
Article
CAS
PubMed
Google Scholar
Eguchi Y, Mizuta T, Sumida Y, Ishibashi E, Kitajima Y, Isoda H, Horie H, Tashiro T, Iwamoto E, Takahashi H, et al: The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease. J Gastroenterol. 2011, 46 (Suppl 1): 70-78.
Article
CAS
PubMed
Google Scholar
Eguchi Y, Eguchi T, Mizuta T, Ide Y, Yasutake T, Iwakiri R, Hisatomi A, Ozaki I, Yamamoto K, Kitajima Y, et al: Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease. J Gastroenterol. 2006, 41: 462-469. 10.1007/s00535-006-1790-5.
Article
CAS
PubMed
Google Scholar
Tsai EC, Boyko EJ, Leonetti DL, Fujimoto WY: Low serum testosterone level as a predictor of increased visceral fat in Japanese-American men. Int J Obes Relat Metab Disord. 2000, 24: 485-491. 10.1038/sj.ijo.0801183.
Article
CAS
PubMed
Google Scholar
Svartberg J, von Muhlen D, Sundsfjord J, Jorde R: Waist circumference and testosterone levels in community dwelling men. The Tromso study. Eur J Epidemiol. 2004, 19: 657-663.
Article
CAS
PubMed
Google Scholar
Zitzmann M: Testosterone deficiency, insulin resistance and the metabolic syndrome. Nat Rev Endocrinol. 2009, 5: 673-681. 10.1038/nrendo.2009.212.
Article
CAS
PubMed
Google Scholar
Laaksonen DE, Niskanen L, Punnonen K, Nyyssonen K, Tuomainen TP, Valkonen VP, Salonen R, Salonen JT: Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men. Diabetes Care. 2004, 27: 1036-1041. 10.2337/diacare.27.5.1036.
Article
CAS
PubMed
Google Scholar
Derby CA, Zilber S, Brambilla D, Morales KH, McKinlay JB: Body mass index, waist circumference and waist to hip ratio and change in sex steroid hormones: the Massachusetts Male Ageing Study. Clin Endocrinol (Oxf). 2006, 65: 125-131. 10.1111/j.1365-2265.2006.02560.x.
Article
CAS
Google Scholar
Tsai EC, Matsumoto AM, Fujimoto WY, Boyko EJ: Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat. Diabetes Care. 2004, 27: 861-868. 10.2337/diacare.27.4.861.
Article
CAS
PubMed
Google Scholar
Pitteloud N, Mootha VK, Dwyer AA, Hardin M, Lee H, Eriksson KF, Tripathy D, Yialamas M, Groop L, Elahi D, Hayes FJ: Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men. Diabetes Care. 2005, 28: 1636-1642. 10.2337/diacare.28.7.1636.
Article
CAS
PubMed
Google Scholar
Kley HK, Nieschlag E, Wiegelmann W, Solbach HG, Kruskemper HL: Steroid hormones and their binding in plasma of male patients with fatty liver, chronic hepatitis and liver cirrhosis. Acta Endocrinol (Copenh). 1975, 79: 275-285.
CAS
Google Scholar
Völzke H, Aumann N, Krebs A, Nauck M, Steveling A, Lerch MM, Rosskopf D, Wallaschofski H: Hepatic steatosis is associated with low serum testosterone and high serum DHEAS levels in men. Int J Androl. 2010, 33: 45-53. 10.1111/j.1365-2605.2009.00953.x.
Article
PubMed
Google Scholar
Haider A, Gooren LJ, Padungtod P, Saad F: Improvement of the metabolic syndrome and of non-alcoholic liver steatosis upon treatment of hypogonadal elderly men with parenteral testosterone undecanoate. Exp Clin Endocrinol Diabetes. 2010, 118: 167-171. 10.1055/s-0029-1202774.
Article
CAS
PubMed
Google Scholar
S-i K: Watanabe N, Numata M, Ogawa T, Matsuzaki S: Increase in the prevalence of fatty liver in Japan over the past 12 years: analysis of clinical background. J Gastroenterol. 2003, 38: 954-961. 10.1007/s00535-003-1178-8.
Article
Google Scholar
Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, Natale S, Vanni E, Villanova N, Melchionda N, Rizzetto M: Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology. 2003, 37: 917-923. 10.1053/jhep.2003.50161.
Article
PubMed
Google Scholar
Kim HJ, Lee KE, Kim DJ, Kim SK, Ahn CW, Lim SK, Kim KR, Lee HC, Huh KB, Cha BS: Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults. Arch Intern Med. 2004, 164: 2169-2175. 10.1001/archinte.164.19.2169.
Article
PubMed
Google Scholar
WHO: Report of a WHO consultation on obesity: prevention and managing, the global epidemic. 1999, Geneva: World Health Organization
Google Scholar
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985, 28: 412-419. 10.1007/BF00280883.
Article
CAS
PubMed
Google Scholar
Chung SJ, Kim D, Park MJ, Kim YS, Kim JS, Jung HC, Song IS: Metabolic syndrome and visceral obesity as risk factors for reflux oesophagitis: a cross-sectional case–control study of 7078 Koreans undergoing health check-ups. Gut. 2008, 57: 1360-1365. 10.1136/gut.2007.147090.
Article
CAS
PubMed
Google Scholar
Maurovich-Horvat P, Massaro J, Fox CS, Moselewski F, O'Donnell CJ, Hoffmann U: Comparison of anthropometric, area- and volume-based assessment of abdominal subcutaneous and visceral adipose tissue volumes using multi-detector computed tomography. Int J Obes (Lond). 2006, 31: 500-506.
Article
Google Scholar
Glantz SA, Slinker BK: Primer of Applied Regression and Analysis of Variance. 1990, New York: McGraw-Hill, 181-238.
Google Scholar
Matsumoto AM, Bremner WJ: Serum testosterone assays–accuracy matters. J Clin Endocrinol Metab. 2004, 89: 520-524. 10.1210/jc.2003-032175.
Article
CAS
PubMed
Google Scholar
Myking O, Aakvaag A, Digranes O: Androgen-oestrogen imbalance in men with chronic alcoholism and fatty liver. Alcohol Alcohol. 1987, 22: 7-15.
CAS
PubMed
Google Scholar
Seidell JC, Bjorntorp P, Sjostrom L, Kvist H, Sannerstedt R: Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels. Metabolism. 1990, 39: 897-901. 10.1016/0026-0495(90)90297-P.
Article
CAS
PubMed
Google Scholar
Kapoor D, Malkin CJ, Channer KS, Jones TH: Androgens, insulin resistance and vascular disease in men. Clin Endocrinol (Oxf). 2005, 63: 239-250. 10.1111/j.1365-2265.2005.02299.x.
Article
CAS
Google Scholar
Pitteloud N, Hardin M, Dwyer AA, Valassi E, Yialamas M, Elahi D, Hayes FJ: Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab. 2005, 90: 2636-2641. 10.1210/jc.2004-2190.
Article
CAS
PubMed
Google Scholar
Tarantino G, Savastano S, Colao A: Hepatic steatosis, low-grade chronic inflammation and hormone/growth factor/adipokine imbalance. World J Gastroenterol. 2010, 16: 4773-4783. 10.3748/wjg.v16.i38.4773.
Article
PubMed
PubMed Central
Google Scholar
Kamada Y, Takehara T, Hayashi N: Adipocytokines and liver disease. J Gastroenterol. 2008, 43: 811-822. 10.1007/s00535-008-2213-6.
Article
CAS
PubMed
Google Scholar
Maggio M: Correlation between Testosterone and the Inflammatory Marker Soluble Interleukin-6 Receptor in Older Men. J Clin Endocrinol Metab. 2006, 91: 345-347. 10.1210/jc.2005-1097.
Article
CAS
PubMed
Google Scholar
Laaksonen DE, Niskanen L, Punnonen K, Nyyssonen K, Tuomainen TP, Salonen R, Rauramaa R, Salonen JT: Sex hormones, inflammation and the metabolic syndrome: a population-based study. Eur J Endocrinol. 2003, 149: 601-608. 10.1530/eje.0.1490601.
Article
CAS
PubMed
Google Scholar
Kupelian V, Chiu GR, Araujo AB, Williams RE, Clark RV, McKinlay JB: Association of sex hormones and C-reactive protein levels in men. Clin Endocrinol (Oxf). 2010, 72: 527-533. 10.1111/j.1365-2265.2009.03713.x.
Article
CAS
Google Scholar
Malkin CJ, Pugh PJ, Jones RD, Kapoor D, Channer KS, Jones TH: The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. J Clin Endocrinol Metab. 2004, 89: 3313-3318. 10.1210/jc.2003-031069.
Article
CAS
PubMed
Google Scholar
Payer J, Banarova A: The influence of testosterone on cardiovascular disease in men. Vnitr Lek. 2010, 56: 702-708.
CAS
PubMed
Google Scholar
Langfort J, Jagsz S, Dobrzyn P, Brzezinska Z, Klapcinska B, Galbo H, Gorski J: Testosterone affects hormone-sensitive lipase (HSL) activity and lipid metabolism in the left ventricle. Biochem Biophys Res Commun. 2010, 399: 670-676. 10.1016/j.bbrc.2010.07.140.
Article
CAS
PubMed
Google Scholar
Joy D, Thava VR, Scott BB: Diagnosis of fatty liver disease: is biopsy necessary?. Eur J Gastroenterol Hepatol. 2003, 15: 539-543.
PubMed
Google Scholar