Fig. 3
From: RFC2 promotes aerobic glycolysis and progression of colorectal cancer
CREB5 regulates RFC2 transcriptional activity. A A sketch map of RFC2 promoter region. B The ov-CREB5 or ov-NC-transfected cells were transfected with promoter WT or mutant and luciferase activity was detected using dual-luciferase reporter assay. C ChIP assay was performed in cells. D Western blot of CREB5 and RFC2 in cells. E RFC2 protein in cells was measured using western blot. F Cell viability was examined using CCK-8 assay. G Wound healing assay was conducted in cells. H Transwell assay was performed in cells. *p < 0.05 vs. ov-NC + RFC2-luc, lgG, si-NC, or si-NC + vector group. #p < 0.05 vs. si-NC + RFC2 group