Fig. 1

RFC2 is upregulated in CRC tissues. A Expression of RFC2 in TCGA-COAD datasets. B Overall survival of patients with CRC in TCGA-COAD datasets, who were divided into high or low RFC2 expression. C and D RFC2 protein expressions in CRC and matched normal tissues were measured using IHC and western blot. E RFC2 protein expression in 50 CRC tissues was assessed by IHC. F Kaplan–Meier survival curve of overall survival. G RFC2 protein levels were detected in normal human colonic epithelial cells (FHC) and five human CRC cell lines (HCT116, LoVo, SW480, Caco-2, and DLD-1). *p < 0.05 vs. Normal or FHC group