Fig. 3

The CD1d-dependency of the steroid-induced liver damage, and the steroid-protective effect of GC, were studied in three groups of CD1d^−/− mice. Mice in group H received the vehicle alone; Group I received Dexamethasone, and Group J received a combination of Dexamethasone with GC for eight weeks. Mice were followed for fasting glucose levels (a); postprandial glucose levels as manifested by glucose tolerance test (b); serum triglyceride levels (c); AST and ALT liver enzymes (d); liver histology (H&E X10) (e); and hepatic triglycerides content (f) (**p < 0.01, *p < 0.05)