Table 1 Baseline characteristics of the patients
Parameter | Total | Cirrhosis | Non-cirrhosis | P value |
|---|---|---|---|---|
(n = 1177) | (n = 616) | (n = 561) | ||
Age (years) | 45.06 ± 10.57 | 47.38 ± 10.28 | 42.52 ± 10.30 | < 0.001 |
Sex, male (%) | 124 (10.5) | 72 (11.7) | 52 (9.3) | 0.209 |
Antiviral therapy (%) | 239 (20.3) | 172 (27.9) | 67 (12.0) | < 0.001 |
NA withdrawal (%) | 171 (14.6) | 115 (18.7) | 56 (10.0) | < 0.001 |
Drug resistance (%) | 21 (1.8) | 8 (1.3) | 13 (2.3) | 0.187 |
TBIL (µmol/L) | 355.57 ± 163.47 | 359.72 ± 168.67 | 351.00 ± 157.60 | 0.361 |
AST (U/L) | 215.50 (107.75, 598.50) | 158.50 (92.00, 360.75) | 316.00 (136.00, 817.00) | < 0.001 |
ALT (U/L) | 304.50 (88.00, 854.75) | 142.00 (65.00, 482.25) | 580.00 (177.50, 1316.00) | < 0.001 |
ALB (g/L) | 34.46 ± 17.49 | 34.65 ± 23.75 | 34.27 ± 4.80 | 0.709 |
PA (mg/L) | 38.05 ± 25.42 | 38.02 ± 24.42 | 38.07 ± 26.50 | 0.977 |
CHE (U/L) | 4035.22 ± 1885.37 | 3697.90 ± 1882.33 | 4406.34 ± 1819.41 | < 0.001 |
PT (s) | 28.03 ± 11.92 | 28.21 ± 9.10 | 27.82 ± 14.41 | 0.572 |
INR | 2.67 ± 2.09 | 2.68 ± 1.75 | 2.65 ± 2.41 | 0.832 |
Fib (g/L) | 1.56 (1.26, 1.96) | 1.51 (1.19, 1.83) | 1.65 (1.32, 2.09) | < 0.001 |
BUN (mmol/L) | 3.81 (2.74, 5.38) | 4.15 (3.00, 6.02) | 3.39 (2.48, 4.68) | < 0.001 |
Cr (µmol/L) | 83.11 ± 61.82 | 87.23 ± 54.99 | 78.57 ± 68.30 | 0.016 |
eGFR | 103.69 ± 39.05 | 98.36 ± 32.18 | 109.56 ± 44.73 | < 0.001 |
FBG (mmol/L) | 4.91 ± 2.88 | 4.81 ± 3.56 | 4.15 ± 1.83 | < 0.001 |
Na (mmol/L) | 136.13 ± 5.87 | 135.55 ± 5.24 | 136.77 ± 6.43 | < 0.001 |
WBC (109/L) | 7.09 (5.38, 9.39) | 6.72 (4.94, 9.02) | 7.31 (5.93, 9.90) | < 0.001 |
NEU (%) | 0.72 ± 0.46 | 0.71 ± 0.38 | 0.73 ± 0.54 | 0.467 |
PLT (109/L) | 117.77 ± 74.32 | 96.61 ± 54.73 | 140.97 ± 85.29 | < 0.001 |
AFP (ng/mL) | 34.85 (10.07, 96.85) | 29.90 (10.21, 96.90) | 35.50 (9.44, 102.90) | < 0.001 |
lgHBV-DNA | 5.07 (3.51, 6.53) | 4.52 (3.04, 6.12) | 5.53 (4.20, 7.04) | < 0.001 |
CTP score | 10.89 ± 1.63 | 11.31 ± 1.48 | 10.42 ± 1.67 | < 0.001 |
CTP score < 7 (%) | 0 (0) | 0 (0) | 0 (0) | 1 |
7 ≤ CTP score < 9 (%) | 253 (21.5) | 83 (13.5) | 170 (30.3) | < 0.001 |
CTP score ≥ 10 (%) | 924 (78.5) | 533 (86.5) | 391 (69.7) | < 0.001 |
MELD score | 25.76 ± 6.67 | 26.48 ± 6.69 | 24.97 ± 6.56 | < 0.001 |
MELD-Na score | 23.95 ± 12.41 | 25.55 ± 11.94 | 22.18 ± 12.69 | < 0.001 |