Table 3 Comparison of clinical features between the groups according to one year virologic response

Age (years)

46.8 ± 11.0

44.4 ± 14.7

0.285

Sex (male, %)

99 (61.5)

32 (65.3)

0.737

HBeAg-positive (%)

77 (47.8)

44 (89.8)

<0.001

Disease status;

CHB/LC (%)

85/76

(52.8/47.2)

41/8

(83.7/16.3)

<0.001

MELD (<7/7-13/>13, %)

109/47/5

(67.7/29.2/3.1)

35/12/2

(71.4/24.5/4.1)

0.768

Serum ALT (IU/L)

198.0 ± 305.7

231.8 ± 475.0

0.557

Serum total bilirubin (mg/dL)

1.12 ± 1.46

1.19 ± 1.77

0.774

Serum albumin(g/dL)

4.10 ± 0.53

4.11 ± 0.60

0.952

INR

1.12 ± 0.17

1.09 ± 0.21

0.319

IVR-3 (−/+)

12/149(7.5/92.5)

25/24 (51.0/49.0)

<0.001

Serum HBV DNA level (log₁₀ IU/mL)

6.30 ± 1.23

7.61 ± 0.97

<0.001

Treatment regimens

0.192

 ETV (n = 105, %)

76 (72.4)

29 (27.6)

 TDF (n = 105, %)

85 (81.0)

20 (19.0)