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Fig. 6 | BMC Gastroenterology

Fig. 6

From: Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis

Fig. 6

TEM of rat adrenocortical zona fasciculate cells at 12 h after pancreatitis. a Adrenocortical cells of CON group with normal nucleus (N) and mitochondria (m). Cytoplasm is filled with characteristic round mitochondria with tubulovesicular internal membranes, ample smooth endoplasmatic reticulums (r), and lipid droplets (l). b Adrenocortical cells of ANP rats in the zona fasciculata. The nucleus was seriously shrunk and dark-stained, chromatin was condensed, membrane of nucleus was tortuous. Some mitochondrion showed coagulation and mitochondrial crista disappeared or showed coagulation. Endoplasmic reticulum was dilated and swollen. c Treatment with 3-AB showed minimal irregularity in nucleus, mitochondria and endoplasmic reticulum. Bar = 6 μm. (TEM × 5000)

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