Skip to main content

Table 4 Multivariate analysis of factors predictive for requiring high tacrolimus doses (> 0.2 mg/kg)

From: The earliest trough concentration predicts the dose of tacrolimus required for remission induction therapy in ulcerative colitis patients

 

Multivariate analysis

 

p

CYP3A5 (*1*1 or *1*3)

6.14 (0.61 - 66.8)

0.12

The initial trough concentration/starting dose > 1 ng/mL/mga

28.0 (3.20 - 631)

<0.0001

  1. aTo estimate appropriate cutoff values, receiver operating characteristic (ROC) curve analysis was performed.
  2. CYP3A5, cytochrome P450 3A4.
Back to article page

BMC Gastroenterology

ISSN: 1471-230X

Contact us