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Table 2 Reproductive factors and risk of oesophageal cancer among female participants

From: Reproductive factors and oesophageal cancer in Chinese women: a case-control study

Variable

Controls n (%)

All types of oesophageal cancer

Squamous cell oesophageal cancer

  

Cases n (%)

Crude OR (95% CI)

Adjusted OR* (95% CI)

Cases n (%)

Crude OR (95% CI)

Adjusted OR* (95% CI)

Children

       

   No

23

9

1

1

8

1

1

   Yes

134

64

1.22 (0.53, 2.78)

1.17 (0.48, 2.85)

60

1.29 (0.54, 3.04)

1.20 (0.47, 3.36)

Number of children born

       

   0

23

9

1

1

8

1

1

   1 or 2

88

45

1.26 (0.71, 2.22)

1.31 (0.72, 2.35)

43

1.40 (0.58, 3.39)

1.34 (0.67, 2.68)

   3 or more

46

19

1.02 (0.51, 2.03)

1.03 (0.49, 2.14)

17

1.06 (0.40, 2.82)

1.02 (0.38, 2.74)

Age at first birth

       

   <22 years

51

17

1

1

15

1

1

   22-24 years

46

20

1.30 (0.61, 2.78)

1.27 (0.54, 2.98)

19

1.40 (0.64, 3.08)

1.31 (0.50, 3.43)

   >24 years

37

27

2.19 (1.05, 4.58)

2.02 (1.01, 4.04)

26

2.39 (1.11, 5.12)

2.12 (1.02, 4.41)

Spontaneous abortion

       

   No

129

55

1

1

51

1

1

   Yes

28

18

1.51 (0.77, 2.94)

1.37 (0.49, 3.83)

17

1.54 (0.77, 3.04)

1.39 (0.50, 3.86)

Age at menarche

       

   <12 years

19

11

1

1

10

1

1

   12-16 years

128

47

0.63 (0.28, 1.43)

0.81 (0.38, 1.86)

44

0.65 (0.28, 1.51)

0.80 (0.37, 1.72)

   >16 years

10

15

2.59 (0.87, 7.71)

2.15 (0.77, 6.00)

14

2.66 (0.87, 8.11)

2.19 (0.79, 6.07)

Age at menopause

       

   <46 years

44

19

1

1

18

1

1

   46-48 years

55

31

1.31 (0.65, 2.61)

1.12 (0.40, 3.14)

29

1.29 (0.63, 2.61)

1.10 (0.35, 2.86)

   >48 years

58

23

0.92 (0.45, 1.89)

0.96 (0.33, 2.79)

21

0.89 (0.42, 1.85)

0.94 (0.31, 2.85)

Years of menstruation

       

   <32 years

41

20

1

1

19

1

1

   33-36 years

60

28

0.96 (0.48, 1.92)

0.94 (0.41, 2.15)

25

0.90 (0.44, 1.84)

0.91 (0.39, 2.12)

   >36 years

56

25

0.92 (0.45, 1.86)

0.93 (0.38, 2.27)

24

0.92 (0.45, 1.90)

0.92 (0.35, 2.42)

  1. * Adjusted for age, reflux, smoking, alcohol use, education, employment, body mass index, and intake of fresh vegetables and fruits.