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Table 3 Logistic regression analysis of the risk of colorectal adenoma

From: MAFLD with central obesity is associated with increased risk of colorectal adenoma and high-risk adenoma

Characteristic

Colorectal adenoma (n = 593)

Control (n = 802)

Univariate analysis

Multivariate analysis

OR (95%CI)

P

OR (95%CI)

P

Age

< 60

326

588

2.3 (1.8, 2.8)

< 0.001

2.2 (1.4, 3.4)

< 0.001

≥ 60

267

214

Sex

Male

376

489

0.9 (0.7, 1.1)

0.355

0.9 (0.6, 1.5)

0.778

Female

217

313

Obesity

Yes

381

300

3.0 (2.4, 3.8)

< 0.001

0.1 (0.1, 0.3)

< 0.001

No

212

502

Central obesity

Yes

168

47

6.4 (4.5, 9.0)

< 0.001

3.3 (1.7, 6.2)

< 0.001

No

425

755

Hypertension

Yes

200

137

2.5 (1.9, 3.2)

< 0.001

2.7 (1.8, 4.2)

< 0.001

No

393

665

Diabetes

Yes

141

41

5.8 (4.0, 8.4)

< 0.001

2.2 (1.1, 4.1)

0.018

No

452

761

Fatty liver

Yes

341

286

2.4 (1.1, 3.7)

0.005

1.9 (0.6, 3.4)

0.007

No

252

536

Smoking

Yes

124

95

2.0 (1.5, 2.6)

< 0.001

2.6 (1.5, 4.4)

< 0.001

No

469

707

BMI

25.7 (24.6, 26.8)

24.5 (23.5, 25.5)

2.1 (1.9, 2.4)

< 0.001

4.3 (3.1, 5.9)

< 0.001

Waist circumference (cm)

85.6 (80.9, 90.5)

80.8 (77.0, 86.1)

1.1 (1.0, 1.1)

< 0.001

1.0 (1.0, 1.0)

0.846

Triglyceride (mg/dL)

126.0 (105.2, 143.1)

98.7 (75.8, 119.6)

1.1 (1.0, 1.1)

< 0.001

1.1 (1.0, 1.1)

< 0.001

HDL-cholesterol (mg/dL)

46.6 (40.6, 51.7)

56.3 (52.1, 60.4)

0.8

(0.7, 0.8)

< 0.001

0.8 (0.7, 0.8)

< 0.001

Fasting glucose (mg/dL)

100.0 (94.4, 105.0)

95.8 (90.0, 101.0)

1.1

(1.1, 1.1)

< 0.001

1.1 (1.1, 1.1)

< 0.001