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Table 2 Laboratory tests in CD patients with and without sarcopenia

From: The association between hemoglobin level and sarcopenia in Chinese patients with Crohn’s disease

Variables

Sarcopenia (n = 114)

Non-sarcopenia group (n = 98)

P-value

FC (µg/g)

948.9 (658.9,1279)

685.5 (291.9,1036.6)

0.001

ESR (mm/h)

35 (18,57)

23 (12,39)

0.003

CRP (mg/L)

24.3 (11.4,57.3)

10.3 (4.0,24.3)

< 0.001

FAR

0.123 ± 0.038

0.094 ± 0.030

< 0.001

NLR

3.48 (2.34,5.01)

3.08 (1.89,4.66)

0.094

Red blood cells (×1012 /L)

4.47 ± 0.59

4.65 ± 0.57

0.027

Leukocytes (×109 /L)

7.72 ± 3.3

7.14 ± 2.52

0.153

Hb (g/L)

116.5 ± 22.8

128.1 ± 21.0

< 0.001

Mean hemoglobin content (pg)

25.98 ± 3.31

27.54 ± 2.99

< 0.001

Mean hemoglobin concentration (g/L)

314.61 ± 15.46

320.83 ± 13.85

0.002

Neutrophils (×109 /L)

4.98 (3.46,6.37)

4.12 (3.33,6.11)

0.192

Lymphocytes (×109 /L)

1.41 (1.1,1.78)

1.45 (1.08,1.97)

0.496

Monocytes (×109 /L)

0.6 (0.41,0.8)

0.51 (0.4,0.7)

0.065

Eosinophils (×109 /L)

0.1 (0.07,0.18)

0.11 (0.06,0.2)

0.634

Basophils (×109 /L)

0.02 (0,0.035)

0.02 (0,0.04)

0.443

PT (s)

13.78 ± 0.87

13.36 ± 0.70

< 0.001

PT activity (%)

96.70 ± 13.82

104.2 ± 13.39

< 0.001

Activated partial thromboplastin time (s)

42.04 ± 5.11

41.55 ± 6.05

0.547

Activated partial thromboplastin ratio

1.215 (1.12, 353)

1.205 (1.11, 1.368)

0.831

Fibrinogen (g/L)

4.47 ± 1.08

3.83 ± 0.96

< 0.001

Thrombin time (s)

17.27 ± 1.45

17.39 ± 1.10

0.501

D-dimer (D-D) (mg/L)

0.345 (0.27, 0.55)

0.28 (0.22,0.377)

0.002

FDP (mg/L)

2.21 (1.89,3.02)

1.78 (1.473,2.355)

< 0.001

Plasma antithrombin (%)

92.43 ± 11.91

93.11 ± 11.89

0.703

Aspartate aminotransferase (U/L)

14 (10,17)

14 (12,18)

0.039

Alanine aminotransferase (U/L)

13 (8,18.25)

13 (9,19.25)

0.425

Total protein (g/L)

64.516 ± 7.730

67.987 ± 7.534

0.001

Albumin (g/L)

37.250 ± 5.816

41.329 ± 5.057

< 0.001

Globulin (g/L)

27.576 ± 5.291

26.665 ± 5.483

0.227

Albumin/globulin

1.390 ± 0.342

1.6248 ± 0.422

< 0.001

Prealbumin (mg/L)

128.92 ± 53.313

155.49 ± 52.766

< 0.001

Glucose (mmol/L)

4.28 (3.94, 4.82)

4.425 (4.07, 4.715)

0.396

  1. Continuous variables conforming to normal distribution are compared between groups using Student t-test; Continuous variables with severe skewed distribution are reported as median (interquartile range) and data are compared between groups using Wilcoxon rank sum test
  2. Note CRP = C-reactive protein; ESR = erythrocyte sedimentation rate; FAR = fibrinogen to albumin ratio; FC = fecal calprotectin; FDP: Fibrin degradation products; Hb = hemoglobin; PT: Prothrombin time; NLR = neutrophil to lymphocyte ratio