Table 2 Comorbidity and symptoms depending on histopathological classification
|  | Collagenous colitis N = 92 | Lymphocytic colitis N = 66 | P-value |
|---|---|---|---|
Comorbidity | |||
 Hypertension Missing value | 34 (37.0) 10 | 20 (30.3) 6 | 0.572 |
 Rheumatoid arthritis Missing value | 18 (19.6) 13 | 15 (22.7) 9 |  |
 Asthma and/or bronchitis Missing value | 16 (17.4) 11 | 9 (13.6) 12 | 0.632 |
 Diabetes Missing value | 6 (6.5) 13 | 5 (7.6) 11 | 0.694 |
 Celiac disease Missing value | 3 (3.3) 17 | 8 (12.1) 13 | 0.050 |
 Gastric ulcer Missing value | 12 (13.0) 14 | 11 (16.7) 8 | 0.749 |
 Thyroid disease Missing value | 16 (17.4) 15 | 12 (18.2) 10 | 1.000 |
 Cancer Missing value | 10 (10.9) 15 | 3 (4.5) 11 | 0.770 |
Drug treatment | |||
 Corticosteroids | 34 (37.0) | 14 (21.2) | 0.037 |
 Proton pump inhibitors | 23 (25.0) | 18 (27.3) | 0.854 |
 Selective serotonin reuptake inhibitors | 11 (12.0) | 19 (28.8) | 0.013 |
 Statins | 17 (18.5) | 11 (16.7) | 0.835 |
 Thyroid hormones | 15 (16.3) | 11 (16.7) | 1.000 |
Gastrointestinal symptoms | |||
 Abdominal pain 5 (1–15) | 35 (12–53) | 41 (12–57) | 0.196 |
 Diarrhea 3 (0–10) | 40 (14–77) | 50 (26–73) | 0.289 |
 Constipation 9 (1–22) | 6 (2–18) | 9 (4–28) | 0.085 |
 Bloating and flatulence 14 (1–29) | 55 (20–77) | 55 (25–71) | 0.805 |
 Vomiting and nausea 2 (0–3) | 7 (1–23) | 13 (2–38) | 0.130 |
 Intestinal influence on daily life 2 (0–18) | 45 (12–74) | 42 (26–84) | 0.151 |
 Psychological well-being 4 (0–16) | 26 (10–54) | 24 (10–50) | 0.751 |