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Table 3 Odds ratios (OR) and 95% confidence intervals (CIs) for the association between each symptom and rectal anatomic site among patients diagnosed with colorectal cancer, stratified by age at diagnosis (N = 626)

From: Colorectal cancer pre-diagnostic symptoms are associated with anatomic cancer site

 

Early Onset (age < 50 years) (n = 116)

Later Onset (age ≥ 50 years) (n = 510)

Symptom:

Odds Ratio (95% CI)ab

Odds Ratio (95% CI)ab

Blood in Stool

6.48 (2.73, 15.41)*

4.03 (2.71, 6.00)*

Changes to Stool

1.72 (0.80, 3.69)

1.87 (1.23, 2.85)*

Abdominal Pain

0.18 (0.08, 0.42)*

0.43 (0.26, 0.70)*

Anemia

0.19 (0.04, 0.94)*

0.48 (0.25, 0.94)*

Other Symptoms

0.18 (0.07, 0.48)*

0.46 (0.26, 0.83)*

Asymptomatic

1.43 (0.22, 9.14)

0.63 (0.42, 0.94)*

  1. *Statistically significant (p-value < 0.05)
  2. aAll associations were adjusted for sex (male, female), and BMI (kg/m2)
  3. bMost results remain statistically significant after a conservative Bonferroni correction for multiple comparisons
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BMC Gastroenterology

ISSN: 1471-230X

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