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Table 1 Clinical characteristics between patients with different treatment protocols

From: Comparative efficacy and safety of Sofosbuvir/Velpatasvir and Danoprevir for the treatment of chronic hepatitis C: the real-world data in China

Parameters

ECS (n = 94)

DNV (n = 84)

All (n = 178)

P

Age, year

48.88 ± 10.66

47.60 ± 10.32

48.27 ± 10.49

0.417

Sex

   

0.098

 Male

66 (70.21%)

49 (58.33%)

115 (64.6%)

 

 Female

28 (29.79%)

35(41.67%)

63 (35.4%)

 

Comorbidity

   

0.054

 No

80 (85.11%)

79 (94.05%)

159 (88.83%)

 

 Yes

14 (14.89%)

5 (5.95%)

19 (10.61%)

 

Log10(HCVRNA), log10(IU/mL)

5.73 ± 1.10

6.03 ± 0.96

5.89 ± 1.04

0.408

AFP, ng/mL

42.84 ± 93.906

5.91 ± 5.28

21.16 ± 62.79

0.012

HCV genotype

   

< 0.001

 1a

2(2.13%)

1 (1.19%)

3 (1.69%)

 

 1b

21 (22.34%)

41 (48.81%)

62 (34.83%)

 

 2a

7 (7.45%)

8 (9.52%)

15 (8.43%)

 

 3a

7 (7.45%)

10 (11.90%)

17 (9.55%)

 

 3b

12 (12.77%)

10 (11.90%)

22 (12.36%)

 

 6a

30 (31.91%)

11 (13.10%)

41 (23.03%)

 

 6e

1(1.06%)

0(0.00%)

1(0.56%)

 

 NA

14(14.89%)

3(3.57%)

17(9.55%)

 

Cirrhosis

   

0.054

 No

80(85.11%)

79 (94.05%)

159 (89.33%)

 

 Yes

14 (14.89%)

5(5.95%)

19 (10.67%)

 

Decompensated cirrhosis

   

0.006

 No

86 (91.49%)

84 (96.97%)

170 (95.51%)

 

 Yes

8 (8.51%)

0 (0)

8 (4.49%)