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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Dietary intervention reverses molecular markers of hepatocellular senescence in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH

Fig. 2

Dietary intervention improves NAFLD Activity Score but not fibrosis stage in GAN DIO-NASH mice. A NAFLD Activity Score (NAS). B Fibrosis stage. C Steatosis score. D Lobular inflammation score. E ballooning degeneration score. *p < 0.05, **p < 0.01, ***p < 0.001 compared to corresponding vehicle control group. One-sided Fisher’s exact test with Bonferroni correction. Comparison of individual pre-post liver biopsy histopathological scores, including (F) NAFLD Activity Score (NAS; composite of steatosis, lobular inflammation and hepatocyte ballooning degeneration scores) and (G) Fibrosis stage. ***p < 0.001 vs. corresponding DIO-NASH vehicle control group (one-sided Fisher’s exact test with Bonferroni correction)

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BMC Gastroenterology

ISSN: 1471-230X

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