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Table 3 Diagnostic performance of each endoscopic modality for diagnosis of H. pylori infection

From: Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy

Endoscopic technique

Sensitivity

(95% CI)

Specificity

(95% CI)

PPV

(95% CI)

NPV

(95% CI)

Accuracy

(95% CI)

M-BLI

Enlarged or elongated pits with obscure SECNs or dense fine irregular vessels

95%

(83.1–99.4)

80%

(67.7–89.2)

76%

(65.5–84.1)

96%

(86.1–98.9)

86%

(77.6–92.1)

M-NBI

Enlarged or elongated pits with obscure SECNs or dense fine irregular vessels

92.5%

(79.6–98.4)

86.7%

(75.4–94.1)

82.2%

(70.7–89.9)

94.6%

(85.3–98.1)

89%

(81.2–94.4)

LCI

Comprehensive findings on LCI were the presence of ≥ 1 of 8 endoscopic findings based on Kyoto classification*

90%

(76.3–97.2)

70%

(56.8–81.2)

66.7%

(57.3–74.9)

91.3%

(80.3–96.4)

78%

(68.6–85.7)

WLI

Comprehensive findings on WLI were the presence of ≥ 1 of 8 endoscopic findings based on Kyoto classification*

80%

(64.4–91.0)

71.7%

(58.6–82.6)

65.3%

(55.0-74.3)

84.3%

(73.9–91.1)

75%

(65.3–83.1)

  1. LCI = Linked Color Imaging, M-BLI = Magnifying Blue Light Imaging, M-NBI = Magnifying Narrow Band Imaging, NPV = Negative predictive value, PPV = Positive predictive value, SECNs = Subepithelial capillary networks, WLI = White Light Imaging
  2. *Eight endoscopic findings based on Kyoto classification included diffuse redness, spotty redness, antral nodularity, sticky mucus, enlarged gastric folds, mucosal edema, xanthoma, and hyperplastic polyp