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Table 2 Diagnostic performance of endoscopic findings for diagnosis of H. pylori status by WLI or LCI

From: Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy

Diagnostic performance to predict  H. pylori-positive status

Findings on each endoscopic mode

Sensitivity

Specificity

PPV

NPV

Accuracy

Mucosal edema

on WLI

75%

78.3%

69.8%

82.5%

77%

 

on LCI

80%

80%

72.7%

85.7%

80%

Diffuse redness

on WLI

57.5%

90%

79.3%

76.1%

77%

 

on LCI

75%

90%

83.3%

84.4%

84%

Spotty redness

on WLI

35%

95%

82.4%

68.7%

71%

 

on LCI

55%

95%

88%

76%

79%

Sticky mucus

on WLI

12.5%

98.3%

83.3%

62.8%

64%

 

on LCI

10%

98.3%

80%

62.1%

63%

Enlarged gastric folds

on WLI

12.5%

100%

100%

63.2%

65%

 

on LCI

12.5%

100%

100%

63.2%

65%

Antral nodularity

on WLI

10%

100%

100%

62.5%

64%

 

on LCI

12.5%

100%

100%

63.2%

65%

Gastric xanthoma

on WLI

2.5%

98.3%

50%

60.2%

60%

 

on LCI

2.5%

96.7%

33.3%

59.8%

59%

Hyperplastic polyp

on WLI

0%

98.3%

0%

59.6%

59%

 

on LCI

0%

98.3%

0%

59.6%

59%

Diagnostic performance to predict  H. pylori-negative status

Findings on each endoscopic mode

Sensitivity

Specificity

PPV

NPV

Accuracy

Presence of RAC

on WLI

86.7%

95%

96.3%

82.6%

90%

 

on LCI

83.3%

85%

89.3%

77.3%

84%

Fundic gland polyps

on WLI

16.7%

100%

100%

55.6%

50%

 

on LCI

16.7%

100%

100%

55.6%

50%

Hematin spots

on WLI

15%

97.5%

90%

56.7%

48%

 

on LCI

16.7%

97.5%

90.9%

43.8%

51%

Red streak

on WLI

8.3%

100%

100%

42.1%

45%

 

on LCI

8.3%

100%

100%

42.1%

45%

  1. LCI = Linked Color Imaging, NPV = Negative predictive value, PPV = Positive predictive value, RAC = Regular arrangement of collecting venules, WLI = White Light Imaging