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Fig. 1 | BMC Gastroenterology

Fig. 1

From: Transcriptional landscape of intestinal environment in DSS-induced ulcerative colitis mouse model

Fig. 1

Separated DEGs into two categories. A A bar graph displaying DEG statistical data. B A volcano plot of DEGs between the UC group and the control group. C Clustering of samples based on the expression level of the leading DEGs. Blue and green scatter points represent insignificant DEGs in the Volcano plot, while red scatter points represent upregulated DEGs and blue scatter points represent downregulated DEGs. The statistical method uses the default cutoff for log2FC, which is \(>|2|\), and the default cutoff for p-value, which is 10e-6, to highlight the most significant genes in red. D Tppp3, Saa3, Nr1d1, and Pappa expression in the controls and UC groups 7 days after DSS (n = 6). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001

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