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Table 2 Brain imaging data of frequently reported brain areas

From: Symptom effects and central mechanism of acupuncture in patients with functional gastrointestinal disorders: a systematic review based on fMRI studies

 

T after treatment VS Baseline

T VS C

 

 Resting state

Event-related((CRD) stimulation)

Resting state

Event-related((CRD) stimulation)

HIPP

(left)ALFFa [23],(Right)ALFFa [25, 30],(lateral)ALFFa [25],(left)FC with insulaa [32]

 

(left)ALFFc [23],(left)FC with inferior frontal gyrusc [32],

 

Temporal Gyrus

(middle)Rehoa [24],(middle)ALFFb [30],(superior)ALFFb [30],(superior)DMN FCa [31]

 

(inferior)ALFFc [23],(superior)ALFFc [23],(middle)ALFFc [23]

 

PrG

(Left)Rehoa [24]

   

BLA

(left)rsFC with right cuneusa [21],rsFC with right HIPP and INS/putamenb [21],(right)with left PCC, right HIPP and INS/putameb [21]

 

(left)rsFC with bilateral INS, putamen and MCC/PCC, HIPPd [21]

 

ACC

rsFC with right SMA and bilateral PrG/Poa [26], rsFC with right precuneus, PCC, HIPP/paraHIPPb [26], (left)ALFFa [30]

activation voxel valueb [27],brain activationa [28]

(right)rsFC with right cerebellumc [26]

 

IC

 

activation voxel valueb [27]

  

PFC

 

activation voxel valueb [27, 29], brain activationa [28]

  

Insula

(Right)ALFFa [30]

 

(left)ALFFc [23]

(right)activationc [28]

PCG

(left)DMN FCa [31]

 

(left)DMN FC↑* [29]

 

Nucleus

  

(right)fALFFc [25]

 

Occipital Gyrus

  

(middle)fALFFd [25]

 

PCC

  

(right)ALFFc [30]

 

Thalamus

 

activationa [28]

 

activationc [28]

  1. T treatment group, C control group, HIPP hippocampuspara, HIPP parahippocampal, PrG precentral gyrus, BLA basolateral amygdala, ACC anterior cingulate cortex, IC insular cortex, INS Insular, PFC prefrontal cortex, CRD colorectal dilatation, PCG Posterior Cingulate Gyrus, PCC posterior cingulate cortex, MCC middle cingulate cortex, PoG postcentral gyrus, DMN Default Mode Network, FC functional constipation, fALFF/ALFF fractional amplitude of low frequency fluctuations/amplitude of low frequency fluctuation, rsFC resting-state functional connectivity; a, greater than baseline; b, lower than baseline; c, greater than control group; d, lower than control group