Fig. 3

Dot plot analysis comparing the estimated blood volume lost (%) between the standard packing and the Floseal™ hemostatic agent (Flowable). The estimated percentage of total blood volume per animal lost (VBL) was calculated according to the formula: VBL= (V/Ve) × 100. “V” was the volume of blood lost (mL), and “Ve” was the estimated volume of blood (mL) according to the weight of the pig. Statistical significance was calculated by Mann-Whitney U test. M 12: Hodges-Lehmann median difference: 13.3%; 95% CI: -6.2–24.6%, p = 0.1228. M 60: Hodges-Lehmann median difference: 18.9%; 95% CI: 13.1–23.1%, p = 0.0002. M120: Hodges-Lehmann median difference:8.8%; 95% CI: 0.3–16.1%, p = 0.0431. Total: Hodges-Lehmann median difference: 41.1%; 95% CI: 18.9–58.0%, p = 0.0034. M12: VBL from injury to minute 12; M60: VBL from minute 12 to minute 60; M120: VBL from minute 60 to minute 120; Total: Total of VBL from injury to minute 120