Table 1 Baseline patient demographics and characteristics according to treatment group
HIP1601 (n = 103) | HGP1705 (n = 100) | P-value | |
|---|---|---|---|
Age (mean ± SD), year | 52.5 ± 13.5 | 51.3 ± 13.9 | 0.499 |
Male | 73 (70.9%) | 73 (73.0%) | 0.736 |
Height (mean ± SD), cm | 166.8 ± 8.6 | 166.1 ± 8.5 | 0.572 |
Weight (mean ± SD), kg | 71.3 ± 12.5 | 70.3 ± 13.0 | 0.333 |
Smoker | 21 (20.4%) | 23 (23.0%) | 0.652 |
Alcohol | 60 (58.3%) | 62 (62.0%) | 0.586 |
LA Classification | 0.369 | ||
Grade A | 70 (68.0%) | 63 (63.0%) | |
Grade B | 27 (26.2%) | 34 (34.0%) | |
Grade C | 6 (5.8%) | 3 (3.0%) | |
Grade D | 0 (0%) | 0 (0%) | |
GERD-related symptoms | |||
Heartburn | 86 (83.5%) | 81 (81.0%) | 0.585 |
Acid regurgitation | 83 (80.6%) | 81 (81.0%) | 0.563 |
Dysphagia | 12 (11.7%) | 20 (20%) | 0.207 |
Epigastric pain | 42 (40.8%) | 46 (46.0%) | 0.878 |
Heartburn (night) | 42 (40.8%) | 47 (47.0%) | 0.372 |
Acid regurgitation (night) | 38 (36.9%) | 41 (41.0%) | 0.549 |
Dysphagia (night) | 3 (2.9%) | 11 (11.0%) | 0.023 |
Epigastric pain (night) | 24 (23.3%) | 21 (21.0%) | 0.693 |
H. pylori infection | 19 (18.5) | 16 (16.0) | 0.645 |
Treatment compliance (mean ± SD) | 97.2 ± 5.5 | 98.1 ± 4.7 | 0.220 |
Number of rescue medication administered (mean ± SD) | 7.8 ± 8.9 | 9.3 ± 12.0 | 0.917 |