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Table 1 Results of sensitivity tests for forward Mendelian randomization analysis

From: Exploration of the causal effects of leukocyte telomere length and four gastrointestinal diseases: a two-sample bidirectional Mendelian randomization study

Exposure

Outcome

N.snp

heterogeneity

pleiotropy

MR Egger

IVW

MR-Egger regression

MR-PRESSO

Q

p-value

Q

p-value

Intercept

p-value

RSSobs

p-value

LTL

IBS

126

141.15

0.14

141.45

0.15

0.00

0.61

143.92

0.15

LTL

GERD

116

113.81

0.49

113.94

0.51

0.00

0.72

115.84

0.51

LTL

PUL

136

100.75

0.99

104.34

0.98

0.00

0.06

106.59

0.97

LTL

NAFLD

120

100.81

0.87

101.88

0.87

-0.01

0.30

104.32

0.88