Biological Arm | Conventional arm | P | |
---|---|---|---|
Population included | 49 | 154 | – |
Observation time (months) | 4646 | 6972 | 0.03* |
Observed events (surgery) | 6 | 23 | |
Incidence rate (events\year) | 0,02 | 0,04 | |
Sex (male: n; %) | 24 (49%) | 97 (63%) | 0.08* |
Age at enrolment (median; range) | 42 (20–78) | 40 (15–85) | 0.71† |
Age at diagnosis (median; range) | 36 (9–78) | 34 (11–66) | 0.43+ |
Disease duration (median; range) | 72 (2–290) | 36 (12–432) | < 0.01† |
Early systemic steroid use | 0.73* | ||
‐ First year ‐ No use in the first year | 27 (56%) 21 (44%) | 91 (59%) 63 (41%) | |
Disease pattern | 0.24* | ||
‐ Penetrating and structuring disease ‐ Non penetrating nor structuring disease | 21 (43%) 28 (57%) | 81 (53%) 73 (47%) | |
Early onset | 0.74* | ||
‐ Before 17-year-old ‐ 17–40-year-old ‐ After 40-year-old | 3 (6%) 30 (61%) 16 (33%) | 15 (10%) 92 (60%) 47 (30%) | |
Ileal or jejunum involvement | 0.39* | ||
‐ Yes ‐ No | 41 (84%) 8 (16%) | 136 (88%) 18 (12%) | |
Active smokers | 0.62* | ||
‐ Yes ‐ No | 17 (39%) 27 (61%) | 66 (43%) 88 (57%) |