Table 4 Effect of different antibiotic use strategies on the prognosis of AP
From: Effect of early antibiotic treatment strategy on prognosis of acute pancreatitis
Antibiotics | None | |||||
|---|---|---|---|---|---|---|
Carbapenem | Third generation cephalosporin | Quinolones | ||||
Biliary Pancreatitis | ||||||
SAP | n = 88 | n = 17 | n = 11 | |||
Laparotomy,(%) | 16(18.2) | 5(31.6) | 8(72.7)*â–´ | |||
Length of hospital stay, days | 45.8 ± 29.5 | 71.1 ± 45.5# | 91.0 ± 49.4* | |||
In-hospital mortality,(%) | 9 (10.2) | 5 (26.3)# | 2(18.2) | |||
AKI,n(%) | 39(44.3) | 8(42.1) | 6(54.5) | |||
CRRT,n(%) | 9(10.2) | 1(5.3) | 3(27.3) | |||
MV,n(%) | 41(46.6) | 11(57.9) | 10(90.9)* | |||
MSAP | n = 10 | n = 187 | n = 15 | n = 51 | ||
Length of hospital stay, days | 32.6 ± 14.6 | 17.8 ± 10.9 | 14.2 ± 5.9 | 36.6 ± 18.4*▴▪ | ||
In-hospital mortality,(%) | 0 | 1(0.5) | 0 | 2(3.9)â–´ | ||
AKI,n(%) | 1(10.0) | 11(5.9) | 1(0.5) | 5(9.8) | ||
MAP | n = 2 | n = 50 | n = 17 | n = 204 | ||
Length of hospital stay, days | 7.0 ± 1.4 | 9.3 ± 4.0 | 8.5 ± 3.2 | 12.2 ± 5.0▪ | ||
Hyperlipidemic pancreatitis | SAP | n = 20 | n = 65 | n = 5 | ||
Laparotomy,(%) | 3 (15.0) | 4 (6.2) | 1(20.0) | |||
Length of hospital stay, days | 47.1 ± 25.2 | 43.5 ± 23.8 | 54.0 ± 39.1 | |||
In-hospital mortality,(%) | 1(5.0) | 5(7.7) | 0 | |||
AKI, n(%) | 11(55.0) | 24(36.9) | 0* | |||
CRRT,n(%) | 15(17.6) | 10(15.4) | 0 | |||
MV,n(%) | 41(46.6) | 11(57.9) | 10(90.9)* | |||
MSAP | n = 7 | n = 66 | n = 5 | n = 46 | ||
Length of hospital stay, days | 41.6 ± 21.0 | 30.1 ± 15.3 | 25.8 ± 10.0 | 21.3 ± 9.9▴ | ||
In-hospital mortality,(%) | 0 | 1(1.4) | 0 | 0 | ||
AKI, n(%) | 1(14.3) | 3(4.5) | 0 | 3(6.5) | ||
MAP | n = 1 | n = 42 | n = 5 | n = 90 | ||
Length of hospital stay, days | – | 8.5 ± 3.2 | 14.0 ± 4.1 | 11.1 ± 4.4 | ||
Alcoholic pancreatitis | SAP | n = 9 | n = 4 | n = 2 | ||
Laparotomy,(%) | 2(22.2) | 0 | 0(0) | |||
Length of hospital stay, days | 65.6 ± 65.1 | 29.2 ± 10.9 | 52.5 ± 26.1▴ | |||
In-hospital mortality,(%) | 3(33.3) | 0 | 0(0) | |||
AKI, n(%) | 4(44.4) | 1(25.0) | 2(100) | |||
CRRT,n(%) | 2(22.2) | 0 | 0(0) | |||
MV,n(%) | 7(83.3) | 2(50.0) | 1(50.0) | |||
MSAP | n = 0 | n = 13 | n = 2 | n = 10 | ||
Length of hospital stay, days | – | 28.0 ± 12.4 | 23.0 ± 15.5 | 0.333 | ||
In-hospital mortality,(%) | – | 1(7.6) | 1(50.0) | 1 | ||
AKI, n(%) | – | 1(7.6) | 1(50.0) | 1 | ||
MAP | n = 1 | n = 7 | n = 1 | n = 22 | ||
Length of hospital stay, days | – | 18.0 ± 5.7 | – | 12.2 ± 5.0 | ||
Other | SAP | n = 10 | n = 12 | n = 1 | ||
Laparotomy,(%) | 3(33.3) | 1(8.3%) | 0(0) | |||
Length of hospital stay, days | 47.25 ± 40.49 | 45.69 ± 27.16 | – | |||
In-hospital mortality,(%) | 0(0.0) | 1(8.3%) | 0(0) | |||
AKI, n(%) | 7(70.0) | 6(50.0) | 2(100) | |||
CRRT,n(%) | 2(20.2) | 0 | 0(0.0) | |||
MV,n(%) | 8(80.0) | 9(75.0) | 1(50) | |||
MSAP | n = 0 | n = 17 | n = 0 | n = 0 | ||
Length of hospital stay, days | – | – | – | – | ||
In-hospital mortality,(%) | – | – | – | – | ||
AKI, n(%) | – | – | – | – | ||
MAP | n = 3 | n = 2 | n = 1 | n = 10 | ||
Length of hospital stay, days | 21.3 ± 6.0 | 18.0 ± 5.7 | – | 12.0 ± 5.3 | ||