Table 4 Multivariable Analyses on the Risk for Advanced Neoplasia and Nonadvanced Adenoma Stratified by Age Groups

Variable

Adjusted OR^a

P

Adjusted OR^a

P

Adjusted OR^a

P

(95% CI)

(95% CI)

(95% CI)

For advanced neoplasia

 Sex (vs. female)

  Male

2.50 (1.05–5.98)

0.039

2.24 (1.72–2.92)

 < 0.001

2.09 (1.86–2.34)

 < 0.001

 Smoking status (vs. never)

  Former

NA^b

0.991

1.13 (0.62–2.07)

0.686

1.09 (0.89–1.34)

0.407

  Current

1.53 (0.60–3.95)

0.375

1.48 (1.09–2.02)

0.012

1.51 (1.32–1.72)

 < 0.001

 Alcohol drinking (vs. never)

  Ever drinker

0.80 (0.20–3.15)

0.753

1.81 (1.28–2.57)

 < 0.001

1.23 (1.05–1.43)

0.009

 Physical activity (vs. irregular exercise)

  Regular exercise

0.87 (0.33–2.29)

0.777

1.07 (0.84–1.37)

0.580

1.01 (0.92–1.12)

0.806

 BMI, kg/m2 (vs. < 25)

  25–29.9

1.03 (0.46–2.26)

0.950

1.11 (0.88–1.40)

0.386

1.26 (1.14–1.40)

 < 0.001

   ≥ 30

1.44 (0.31–6.76)

0.645

1.35 (0.85–2.15)

0.209

1.47 (1.22–1.78)

 < 0.001

For nonadvanced neoplasia

  Sex (vs. female)

  Male

1.92 (1.46–2.52)

 < 0.001

1.91 (1.71–2.14)

 < 0.001

1.66 (1.55–1.77)

 < 0.001

 Smoking status (vs. never)

  Former

0.62 (0.16–2.32)

0.477

0.81 (0.60–1.10)

0.181

1.13 (1.00–1.28)

0.058

  Current

1.21 (0.86–1.69)

0.275

1.27 (1.10–1.46)

0.001

1.40 (1.29–1.52)

 < 0.001

 Alcohol drinking (vs. never)

  Ever drinker

1.15 (0.73–1.81)

0.536

1.22 (1.01–1.47)

0.040

1.14 (1.03–1.26)

0.010

 Physical activity (vs. irregular exercise)

  Regular exercise

1.22 (0.91–1.65)

0.185

1.05 (0.94–1.17)

0.374

0.98 (0.93–1.04)

0.543

 BMI, kg/m2 (vs. < 25)

  25–29.9

1.20 (0.93–1.56)

0.160

1.08 (0.98–1.20)

0.117

1.22 (1.15–1.30)

 < 0.001

  ≥ 30

1.40 (0.79–2.48)

0.250

1.23 (0.99–1.52)

0.058

1.49 (1.33–1.67)

 < 0.001