Characteristic | Total participants (n = 4,117,897) | High-risk participants (n = 217,164) | P value |
---|---|---|---|
Age (years), mean (SD) | 60.80 (8.35) | 63.51 (7.59) |  < 0.001 |
40–44 | 74,832 (1.8) | 1456 (0.7) |  < 0.001 |
45–49 | 384,721 (9.3) | 9521 (4.4) | |
50–54 | 600,919 (14.6) | 19,817 (9.1) | |
55–59 | 732,385 (17.8) | 33,446 (15.4) | |
60–64 | 735,745 (17.9) | 41,960 (19.3) | |
65–69 | 866,164 (21.0) | 56,502 (26.0) | |
70–74 | 723,131 (17.6) | 54,462 (25.1) | |
Sex, n (%) | Â | Â | Â |
Male | 1,927,100 (46.8) | 89,371 (41.2) |  < 0.001 |
Female | 2,190,797 (53.2) | 127,793 (58.8) | |
Marital status, n (%) | Â | Â | Â |
Married | 3,929,779 (95.4) | 181,399 (83.5) |  < 0.001 |
Unmarried | 47,734 (1.2) | 1826 (0.8) | |
Divorced | 29,129 (0.7) | 5740 (2.6) | |
Widowed | 91,535 (2.2) | 27,966 (12.9) | |
Unknown | 19,720 (0.5) | 233 (0.1) | |
Educational level, n (%) | Â | Â | Â |
Primary school or below | 1,046,679 (25.4) | 62,378 (28.7) |  < 0.001 |
Middle school | 2,615,698 (63.5) | 134,673 (62.0) | |
College or above | 411,378 (10.0) | 19,454 (9.0) | |
Unknown | 44,142 (1.1) | 659 (0.3) | |
Factors for risk stratification, n (%) | Â | Â | Â |
Chronic diarrhoea | 116,248 (2.8) | 44,888 (20.7) |  < 0.001 |
Chronic constipation | 185,216 (4.5) | 56,691 (26.1) |  < 0.001 |
Mucus bloody stool | 40,839 (1.0) | 26,900 (12.4) |  < 0.001 |
Chronic appendicitis/appendectomy | 76,864 (1.9) | 27,485 (12.7) |  < 0.001 |
Chronic cholecystitis/cholecystectomy | 61,156 (1.5) | 24,808 (11.4) |  < 0.001 |
Psychiatric trauma | 132,984 (3.2) | 48,719 (22.4) |  < 0.001 |
Personal history of any cancer | 12,192 (0.3) | 12,192 (5.6) |  < 0.001 |
Personal history of colorectal polyps | 11,618 (0.3) | 11,618 (5.3) |  < 0.001 |
Family history of CRC in FDR | 21,415 (0.5) | 21,415 (9.9) |  < 0.001 |
FIT positive | 88,459 (2.1) | 88,459 (40.7) |  < 0.001 |