Fig. 1
From: Macrophage polarization toward M1 phenotype in T cell transfer colitis model
Development of colitis in the T cell transfer colitis model. (A–C) Representative colonoscopic pictures of the colon tissues of sham-treated mice (A) 3 (B) and 5 (C) weeks after T cell transfer. (D) Colonoscopic scores of sham-treated mice 3 and 5 weeks after T cell transfer. (E–G) Representative microphotographs of the colon tissues of sham-treated mice (E) 3 (F) and 5 (G) weeks after T cell transfer. Scale bar, 100 μm. Results are expressed as the mean ± SD. **p < 0.01 and *p < 0.05 via Steel’s test vs. sham-treated group. n = 5–8 animals per group. Immune cell infiltration (asterisk), goblet cell and crypt loss (arrowhead) and crypt abscess (arrow). (H–K) Histological scores of sham-treated mice 3 and 5 weeks after T cell transfer. Epithelial hyperplasia (H), goblet cell and crypt loss (I), inflammatory infiltration (J), and total histological score (K)