A meta-analysis of the prognostic impact of tissue golgi protein 73 (tGP73) in hepatocellular carcinoma

BMC Gastroenterology

Table 3 Results of subgroup analysis for the effect of tGP73 on HCC overall survival

Parameter	N of studies	Effect model	Amalgamative HR(95% CI)	P value	Heterogeneity test
Parameter	N of studies		Amalgamative HR(95% CI)	P value	I² (%)	P value
Overall	11	Random	1.87(1.41–2.48)	0.000	58	0.008
HR extraction method
report	2	Random	1.35 (0.95, 1.92)	0.090	90	0.002
survival curve	9	Fixed	1.93 (1.63, 2.27)	0.000	14	0.320
Sample size
≥ 100	5	Fixed	2.09 (1.73, 2.53)	0.000	48	0.100
<100	6	Random	2.16 (1.82, 2.56)	0.020	62	0.020
Duration of follow-up(months)
≥ 80	4	Fixed	1.72(1.38, 2.14)	0.000	0	0.990
<80	7	Random	2.23 (1.74, 2.88)	0.000	72	0.001

CI – confidence interval, tGP73 – tissue Golgi protein 73, HCC – hepatocellular carcinoma, HR – hazard ratio, N – number

ISSN: 1471-230X