Table 2 Association between high tGP73 expression and clinicopathological features
Parameter | N of studies | N of patients | Effect model | OR (95% CI) | P value | Heterogeneity test | |
|---|---|---|---|---|---|---|---|
I2 (%) | P value | ||||||
HBV (+/-) | 5 | 451 | Random | 1.31(0.55,3.14) | 0.540 | 58 | 0.050 |
AFP value (>400/≤400) | 6 | 648 | Random | 0.88(0.60,1.28) | 0.510 | 64 | 0.020 |
Edmondson grade (III-IV/I-II) | 3 | 448 | Random | 3.03(2.01,4.57) | 0.000 | 89 | 0.000 |
Vascular invasion (+/-) | 4 | 491 | Fixed | 1.72(1.12,2.64) | 0.010 | 0 | 0.400 |
TNM Stage (III–IV/I–II) | 2 | 163 | Fixed | 5.89(2.31,14.99) | 0.000 | 0 | 0.770 |
Liver cirrhosis | 3 | 453 | Fixed | 1.03(0.68, 1.55) | 0.900 | 6 | 0.350 |
Tumour number (multiple/single) | 4 | 399 | Fixed | 2.44(1.37, 3.68) | 0.001 | 44 | 0.150 |
Tumour size (≥ 3 cm/< 3 cm) | 3 | 311 | Fixed | 0.92(0.55, 1.53) | 0.750 | 0 | 0.690 |
Recurrence status | 3 | 311 | Random | 1.92(1.10, 3.38) | 0.020 | 62 | 0.070 |