Table 1 The basic characteristics of the enrolled studies
Author | Year | Study region | Sample size | Treatment | differentiation(Edmondson grade) | stage of tumour(TNM stage) | Cut-off value | OS HR(95% CI) | DFS HR(95% CI) | Method of extraction | follow-up periods(months) | NOS score |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bao et al. [8] | 2013 | China | 75 | Hepatectomy | I-IV | I-IV | 20% | 3.53(1.39–8.57) | NA | survival curve | 20 | 6 |
Sai et al. [17] | 2015 | China | 88 | Hepatectomy | G1-G3 | I-IV | 25% | 1.65(0.66–4.16) | NA | survival curve | 60 | 7 |
Jiang et al. [10] | 2016 | China | 90 | Hepatectomy | I-II | NA | 25% | 1.7(0.92–3.16) | NA | survival curve | 96 | 8 |
Yang et al. [11] | 2017 | China | 64 | Hepatectomy | G1-G3 | NA | NA | NA | 1.63(0.44–6.10) | survival curve | 83 | 7 |
Mao et al. [12] | 2018 | China | 54 | Hepatectomy | G1-G3 | NA | 1.6 relative units | 1.14(0.03–37.86) | 1.2(0.30–4.87) | survival curve | 67 | 8 |
Chen et al. [13] | 2013 | Taiwan | 193 | Hepatectomy | NA | I-III | 150 scores | 1.696(1.160–2.479) | 1.765(1.100–2.026) | report | 172 | 7 |
Shan et al. [14] | 2013 | China | 62 | Hepatectomy | NA | I-IV | NA | 0.338(0.132–0.855) | 0.485(0.242–0.972) | report | 30 | 6 |
Dai(1) et al. [9] | 2015 | China | 217 | Hepatectomy | NA | NA | NA | 2.52(1.56–4.09) | NA | survival curve | 68 | 7 |
Dai(2) et al. [9] | 2015 | China | 173 | Hepatectomy | NA | NA | NA | 3.76(2.26–6.27) | NA | survival curve | 68 | 7 |
Ye(1) et al. [18] | 2016 | China | 91 | Hepatectomy | G1、G3 | I-III | 2 scores | 1.59(0.84–3.02) | 2.28(1.30-4.00) | survival curve | 140 | 7 |
Ye(2) et al. [18] | 2016 | China | 282 | Hepatectomy | G1、G3 | I-III | 2 scores | 1.79(1.28–2.50) | 1.68(1.21–2.23) | survival curve | 120 | 7 |
Li et al. [19] | 2015 | China | 180 | Hepatectomy | I-IV | NA | 25% | 1.96(1.18–3.27) | NA | survival curve | 60 | 6 |