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Table 2 Clinical trials comprising patients with HCC and developing pulmonary metastases after TIPS placement

From: Risks and benefits of TIPS in HCC and other liver malignancies: a literature review

Author

Study type

Enrolled patients

Liver malignancy

Shunts traversing the tumour

Cases with pulmonary metastases post TIPS

Time between TIPS placement and diagnosis of pulmonary metastases (months)

Tsauo J, et al. 2021 [17]

Retrospective, single-centre

126

HCC (n = 126)

8

3, amongst them no shunt traversing the tumour

3.9–32.9

Zhao H, et al. 2018 [39]

Systematic review

280

HCC (n = 280)

35

2

5 and 72

Wallace M, et al. 2003 [67]

Case series

9

HCC (n = 7)

Pancreatic neuroendocrine metastases (n = 1)

Metastatic gastrointestinal stroma tumour (n = 1)

9

2

5 and 10

  1. TIPS: transjugular intrahepatic portosystemic shunt; HCC: hepatocellular carcinoma